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3C6Q
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BU of 3c6q by Molmil
Apo and ligand-bound form of a thermophilic glucose/xylose binding protein
Descriptor: Sugar ABC transporter, periplasmic sugar-binding protein, beta-D-xylopyranose
Authors:Cuneo, M.J, Hellinga, H.W.
Deposit date:2008-02-05
Release date:2008-02-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Open to closed transition of a thermophilic glucose binding protein
To be Published
8DWV
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BU of 8dwv by Molmil
Full-length wild type SPOP
Descriptor: Speckle-type POZ protein
Authors:Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H.
Deposit date:2022-08-02
Release date:2023-01-18
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.
Mol.Cell, 83, 2023
2B3B
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BU of 2b3b by Molmil
Thermus thermophilus Glucose/Galactose Binding Protein With Bound Glucose
Descriptor: alpha-D-glucopyranose, beta-D-glucopyranose, glucose-binding protein
Authors:Cuneo, M.J, Changela, A, Warren, J.J, Beese, L.S, Hellinga, H.W.
Deposit date:2005-09-20
Release date:2006-07-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The crystal structure of a thermophilic glucose binding protein reveals adaptations that interconvert mono and di-saccharide binding sites.
J.Mol.Biol., 362, 2006
2B3F
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BU of 2b3f by Molmil
Thermus thermophilus Glucose/Galactose Binding Protein Bound With Galactose
Descriptor: beta-D-galactopyranose, glucose-binding protein
Authors:Cuneo, M.J, Changela, A, Warren, J.J, Beese, L.S, Hellinga, H.W.
Deposit date:2005-09-20
Release date:2006-07-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:The crystal structure of a thermophilic glucose binding protein reveals adaptations that interconvert mono and di-saccharide binding sites.
J.Mol.Biol., 362, 2006
2O7I
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BU of 2o7i by Molmil
The X-ray crystal structure of a thermophilic cellobiose binding protein bound with cellobiose
Descriptor: Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose
Authors:Cuneo, M.J, Hellinga, H.W.
Deposit date:2006-12-11
Release date:2007-03-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Analysis of Semi-specific Oligosaccharide Recognition by a Cellulose-binding Protein of Thermotoga maritima Reveals Adaptations for Functional Diversification of the Oligopeptide Periplasmic Binding Protein Fold.
J.Biol.Chem., 284, 2009
8DWT
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BU of 8dwt by Molmil
SPOP W22R Form 2
Descriptor: Speckle-type POZ protein
Authors:Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H.
Deposit date:2022-08-02
Release date:2023-01-18
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.
Mol.Cell, 83, 2023
8DWU
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BU of 8dwu by Molmil
SPOP W22R Form 1
Descriptor: Speckle-type POZ protein
Authors:Cuneo, M.J, Mittag, T, O'Flynn, B.
Deposit date:2022-08-02
Release date:2023-01-18
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.
Mol.Cell, 83, 2023
8DWS
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BU of 8dws by Molmil
Full-length E47K SPOP
Descriptor: Speckle-type POZ protein
Authors:Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H.
Deposit date:2022-08-02
Release date:2023-01-18
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.
Mol.Cell, 83, 2023
3I5O
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BU of 3i5o by Molmil
The X-ray crystal structure of a thermophilic cellobiose binding protein bound with cellopentaose
Descriptor: Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose
Authors:Cuneo, M.J, Hellinga, H.W.
Deposit date:2009-07-06
Release date:2009-07-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Analysis of Semi-specific Oligosaccharide Recognition by a Cellulose-binding Protein of Thermotoga maritima Reveals Adaptations for Functional Diversification of the Oligopeptide Periplasmic Binding Protein Fold.
J.Biol.Chem., 284, 2009
3K75
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BU of 3k75 by Molmil
X-ray crystal structure of reduced XRCC1 bound to DNA pol beta catalytic domain
Descriptor: DNA polymerase beta, DNA repair protein XRCC1
Authors:Cuneo, M.J, London, R.E.
Deposit date:2009-10-12
Release date:2010-04-28
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity.
Proc.Natl.Acad.Sci.USA, 107, 2010
3K77
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BU of 3k77 by Molmil
X-ray crystal structure of XRCC1
Descriptor: DNA repair protein XRCC1
Authors:Cuneo, M.J, London, R.E.
Deposit date:2009-10-12
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.597 Å)
Cite:Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LQC
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BU of 3lqc by Molmil
X-ray crystal structure of oxidized XRCC1 bound to DNA pol beta Palm thumb domain
Descriptor: CARBONATE ION, DNA polymerase beta, DNA repair protein XRCC1, ...
Authors:Cuneo, M.J, Krahn, J.M, London, R.E.
Deposit date:2010-02-09
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.349 Å)
Cite:Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity.
Proc.Natl.Acad.Sci.USA, 107, 2010
3PC7
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BU of 3pc7 by Molmil
X-ray crystal structure of the DNA ligase III-alpha BRCT domain.
Descriptor: DNA ligase 3
Authors:Cuneo, M.J, Krahn, J.M, London, R.E.
Deposit date:2010-10-21
Release date:2011-06-15
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The structural basis for partitioning of the XRCC1/DNA ligase III-{alpha} BRCT-mediated dimer complexes.
Nucleic Acids Res., 39, 2011
3PC6
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BU of 3pc6 by Molmil
X-ray crystal structure of the second XRCC1 BRCT domain.
Descriptor: DNA repair protein XRCC1
Authors:Cuneo, M.J, Krahn, J.M, London, R.E.
Deposit date:2010-10-21
Release date:2011-06-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structural basis for partitioning of the XRCC1/DNA ligase III-{alpha} BRCT-mediated dimer complexes.
Nucleic Acids Res., 39, 2011
3PC8
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BU of 3pc8 by Molmil
X-ray crystal structure of the heterodimeric complex of XRCC1 and DNA ligase III-alpha BRCT domains.
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA ligase 3, DNA repair protein XRCC1, ...
Authors:Cuneo, M.J, Krahn, J.M, London, R.E.
Deposit date:2010-10-21
Release date:2011-06-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:The structural basis for partitioning of the XRCC1/DNA ligase III-{alpha} BRCT-mediated dimer complexes.
Nucleic Acids Res., 39, 2011
3QVG
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BU of 3qvg by Molmil
XRCC1 bound to DNA ligase
Descriptor: DNA ligase 3, DNA repair protein XRCC1
Authors:Cuneo, M.J, Krahn, J.M, London, R.E.
Deposit date:2011-02-25
Release date:2011-06-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The structural basis for partitioning of the XRCC1/DNA ligase III-{alpha} BRCT-mediated dimer complexes.
Nucleic Acids Res., 39, 2011
2FN9
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BU of 2fn9 by Molmil
Thermotoga maritima Ribose Binding Protein Unliganded Form
Descriptor: ribose ABC transporter, periplasmic ribose-binding protein
Authors:Cuneo, M.J, Changela, A, Tian, Y, Beese, L.S, Hellinga, H.W.
Deposit date:2006-01-10
Release date:2007-01-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Ligand-induced conformational changes in a thermophilic ribose-binding protein.
Bmc Struct.Biol., 8, 2008
2FN8
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BU of 2fn8 by Molmil
Thermotoga maritima Ribose Binding Protein Ribose Bound Form
Descriptor: beta-D-ribopyranose, ribose ABC transporter, periplasmic ribose-binding protein
Authors:Cuneo, M.J, Changela, A.
Deposit date:2006-01-10
Release date:2007-01-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Ligand-induced conformational changes in a thermophilic ribose-binding protein.
Bmc Struct.Biol., 8, 2008
2FNC
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BU of 2fnc by Molmil
Thermotoga maritima maltotriose binding protein bound with maltotriose.
Descriptor: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose ABC transporter, periplasmic maltose-binding protein
Authors:Cuneo, M.J, Changela, A.
Deposit date:2006-01-10
Release date:2007-01-16
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of redundant maltotriose binding proteins from the thermophile Thermotoga maritima
To be Published
2GH9
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BU of 2gh9 by Molmil
Thermus thermophilus maltotriose binding protein bound with maltotriose
Descriptor: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose/maltodextrin-binding protein
Authors:Cuneo, M.J, Changela, A, Beese, L.S, Hellinga, H.W.
Deposit date:2006-03-27
Release date:2007-02-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural adaptations that modulate monosaccharide, disaccharide, and trisaccharide specificities in periplasmic maltose-binding proteins.
J.Mol.Biol., 389, 2009
2GHB
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BU of 2ghb by Molmil
Thermotoga maritima maltotriose binding protein, ligand free form
Descriptor: maltose ABC transporter, periplasmic maltose-binding protein
Authors:Cuneo, M.J, Changela, A, Hocker, B, Beese, L.S, Hellinga, H.W.
Deposit date:2006-03-27
Release date:2007-02-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:T. maritima maltotriose binding protein open form
To be Published
2GHA
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BU of 2gha by Molmil
Thermotoga maritima maltotriose binding protein bound with maltotriose
Descriptor: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, maltose ABC transporter, periplasmic maltose-binding protein
Authors:Cuneo, M.J, Changela, A, Hocker, B, Beese, L.S, Hellinga, H.W.
Deposit date:2006-03-27
Release date:2007-02-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:T. maritima maltotriose binding protein
To be Published
2HPH
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BU of 2hph by Molmil
High resolution structure of E. coli glucose/galactose binding protein bound with glucose
Descriptor: CALCIUM ION, D-galactose-binding periplasmic protein, beta-D-glucopyranose
Authors:Cuneo, M.J, Hellinga, H.W.
Deposit date:2006-07-17
Release date:2007-03-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:High resolution structure of E. coli glucose/galactose binding protein bound with glucose
To be Published
2HPG
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BU of 2hpg by Molmil
The crystal structure of a thermophilic TRAP periplasmic binding protein
Descriptor: ABC transporter, periplasmic substrate-binding protein
Authors:Cuneo, M.J, Hellinga, H.W.
Deposit date:2006-07-17
Release date:2007-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of a periplasmic binding protein in the tripartite ATP-independent transporter family reveals a tetrameric assembly that may have a role in ligand transport.
J.Biol.Chem., 283, 2008
2IPM
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BU of 2ipm by Molmil
Crystal structure of a disulfide mutant glucose binding protein
Descriptor: CALCIUM ION, D-galactose-binding periplasmic protein, beta-D-glucopyranose
Authors:Cuneo, M.J, Hellinga, H.W.
Deposit date:2006-10-12
Release date:2007-03-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:The free energy cost of domain reorganization in E. coli glucose binding protein
To be Published

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