Author results

1RNH
  • Download 1rnh
  • View 1rnh
Molmil generated image of 1rnh
STRUCTURE OF RIBONUCLEASE H PHASED AT 2 ANGSTROMS RESOLUTION BY MAD ANALYSIS OF THE SELENOMETHIONYL PROTEIN
Descriptor:RIBONUCLEASE HI, SULFATE ION
Authors:Yang, W., Hendrickson, W.A., Crouch, R.J., Satow, Y.
Deposit date:1990-07-11
Release date:1991-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of ribonuclease H phased at 2 A resolution by MAD analysis of the selenomethionyl protein.
Science, 249, 1990
1ZBF
  • Download 1zbf
  • View 1zbf
Molmil generated image of 1zbf
CRYSTAL STRUCTURE OF B. HALODURANS RNASE H CATALYTIC DOMAIN MUTANT D132N
Descriptor:ribonuclease H-related protein, SULFATE ION
Authors:Nowotny, M., Gaidamakov, S.A., Crouch, R.J., Yang, W.
Deposit date:2005-04-08
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structures of RNase H Bound to an RNA/DNA Hybrid: Substrate Specificity and Metal-Dependent Catalysis.
Cell(Cambridge,Mass.), 121, 2005
1ZBI
  • Download 1zbi
  • View 1zbi
Molmil generated image of 1zbi
BACILLUS HALODURANS RNASE H CATALYTIC DOMAIN MUTANT D132N IN COMPLEX WITH 12-MER RNA/DNA HYBRID
Descriptor:5'-R(*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*C)-3', 5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3', ribonuclease H-related protein, ...
Authors:Nowotny, M., Gaidamakov, S.A., Crouch, R.J., Yang, W.
Deposit date:2005-04-08
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structures of RNase H Bound to an RNA/DNA Hybrid: Substrate Specificity and Metal-Dependent Catalysis.
Cell(Cambridge,Mass.), 121, 2005
1ZBL
  • Download 1zbl
  • View 1zbl
Molmil generated image of 1zbl
BACILLUS HALODURANS RNASE H CATALYTIC DOMAIN MUTANT D192N IN COMPLEX WITH 12-MER RNA/DNA HYBRID
Descriptor:5'-R(*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*C)-3', 5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3', ribonuclease H-related protein, ...
Authors:Nowotny, M., Gaidamakov, S.A., Crouch, R.J., Yang, W.
Deposit date:2005-04-08
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of RNase H Bound to an RNA/DNA Hybrid: Substrate Specificity and Metal-Dependent Catalysis.
Cell(Cambridge,Mass.), 121, 2005
2QK9
  • Download 2qk9
  • View 2qk9
Molmil generated image of 2qk9
HUMAN RNASE H CATALYTIC DOMAIN MUTANT D210N IN COMPLEX WITH 18-MER RNA/DNA HYBRID
Descriptor:5'-R(*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3', 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*T)-3', Ribonuclease H1, ...
Authors:Nowotny, M., Gaidamakov, S.A., Ghirlando, R., Cerritelli, S.M., Crouch, R.J., Yang, W.
Deposit date:2007-07-10
Release date:2007-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription
Mol.Cell, 28, 2007
2QKB
  • Download 2qkb
  • View 2qkb
Molmil generated image of 2qkb
HUMAN RNASE H CATALYTIC DOMAIN MUTANT D210N IN COMPLEX WITH 20-MER RNA/DNA HYBRID
Descriptor:5'-R(*GP*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3'), 5'-D(*DGP*DGP*DAP*DAP*DTP*DCP*DAP*DGP*DGP*DTP*DGP*DTP*DCP*DGP*DCP*DAP*DCP*DTP*DCP*DT)-3', Ribonuclease H1, ...
Authors:Nowotny, M., Gaidamakov, S.A., Ghirlando, R., Cerritelli, S.M., Crouch, R.J., Yang, W.
Deposit date:2007-07-10
Release date:2007-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription
Mol.Cell, 28, 2007
2QKK
  • Download 2qkk
  • View 2qkk
Molmil generated image of 2qkk
HUMAN RNASE H CATALYTIC DOMAIN MUTANT D210N IN COMPLEX WITH 14-MER RNA/DNA HYBRID
Descriptor:5'-R(*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3', 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*G)-3', Ribonuclease H1, ...
Authors:Nowotny, M., Gaidamakov, S.A., Ghirlando, R., Cerritelli, S.M., Crouch, R.J., Yang, W.
Deposit date:2007-07-11
Release date:2007-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription
Mol.Cell, 28, 2007
3BSU
  • Download 3bsu
  • View 3bsu
Molmil generated image of 3bsu
HYBRID-BINDING DOMAIN OF HUMAN RNASE H1 IN COMPLEX WITH 12-MER RNA/DNA
Descriptor:RNA (5'-R(*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*C)-3'), DNA (5'-D(*DGP*DAP*DAP*DTP*DCP*DAP*DGP*DGP*(5IU)P*DGP*DTP*DC)-3'), Ribonuclease H1, ...
Authors:Nowotny, M., Cerritelli, S.M., Ghirlando, R., Gaidamakov, S.A., Crouch, R.J., Yang, W.
Deposit date:2007-12-26
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD.
Embo J., 27, 2008
3O3F
  • Download 3o3f
  • View 3o3f
Molmil generated image of 3o3f
T. MARITIMA RNASE H2 D107N IN COMPLEX WITH NUCLEIC ACID SUBSTRATE AND MAGNESIUM IONS
Descriptor:Ribonuclease HII, DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), ...
Authors:Rychlik, M.P., Chon, H., Cerritelli, S.M., Klimek, P., Crouch, R.J., Nowotny, M.
Deposit date:2010-07-24
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage.
Mol.Cell, 40, 2010
3O3G
  • Download 3o3g
  • View 3o3g
Molmil generated image of 3o3g
T. MARITIMA RNASE H2 IN COMPLEX WITH NUCLEIC ACID SUBSTRATE AND CALCIUM IONS
Descriptor:Ribonuclease HII, DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), ...
Authors:Rychlik, M.P., Chon, H., Cerritelli, S.M., Klimek, P., Crouch, R.J., Nowotny, M.
Deposit date:2010-07-24
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage.
Mol.Cell, 40, 2010
3O3H
  • Download 3o3h
  • View 3o3h
Molmil generated image of 3o3h
T. MARITIMA RNASE H2 D107N IN COMPLEX WITH NUCLEIC ACID SUBSTRATE AND MANGANESE IONS
Descriptor:Ribonuclease HII, DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), ...
Authors:Rychlik, M.P., Chon, H., Cerritelli, S.M., Klimek, P., Crouch, R.J., Nowotny, M.
Deposit date:2010-07-24
Release date:2010-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage.
Mol.Cell, 40, 2010
3PUF
  • Download 3puf
  • View 3puf
Molmil generated image of 3puf
CRYSTAL STRUCTURE OF HUMAN RNASE H2 COMPLEX
Descriptor:Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C
Authors:Figiel, M., Chon, H., Cerritelli, S.M., Cybulska, M., Crouch, R.J., Nowotny, M.
Deposit date:2010-12-04
Release date:2010-12-22
Last modified:2012-08-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The structural and biochemical characterization of human RNase H2 complex reveals the molecular basis for substrate recognition and Aicardi-Goutieres syndrome defects.
J.Biol.Chem., 286, 2011
4HHT
  • Download 4hht
  • View 4hht
Molmil generated image of 4hht
T. MARITIMA RNASE H2 G21S IN COMPLEX WITH NUCLEIC ACID SUBSTRATE AND CALCIUM IONS
Descriptor:Ribonuclease HII, DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), ...
Authors:Rychlik, M.P., Nowotny, M.
Deposit date:2012-10-10
Release date:2013-02-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:RNase H2 roles in genome integrity revealed by unlinking its activities.
Nucleic Acids Res., 41, 2013
1ASW
  • Download 1asw
  • View 1asw
Molmil generated image of 1asw
AVIAN SARCOMA VIRUS INTEGRASE CATALYTIC CORE DOMAIN CRYSTALLIZED FROM 20% PEG 4000, 10% ISOPROPANOL, HEPES PH 7.5 USING SELENOMETHIONINE SUBSTITUTED PROTEIN; DATA COLLECTED AT-165 DEGREES C
Descriptor:AVIAN SARCOMA VIRUS INTEGRASE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ISOPROPYL ALCOHOL
Authors:Bujacz, G., Jaskolski, M., Alexandratos, J., Wlodawer, A.
Deposit date:1995-08-25
Release date:1995-11-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High-resolution structure of the catalytic domain of avian sarcoma virus integrase.
J.Mol.Biol., 253, 1995
1KVA
  • Download 1kva
  • View 1kva
Molmil generated image of 1kva
E. COLI RIBONUCLEASE HI D134A MUTANT
Descriptor:RIBONUCLEASE H
Authors:Kashiwagi, T., Jeanteur, D., Haruki, M., Katayanagi, K., Kanaya, S., Morikawa, K.
Deposit date:1996-10-04
Release date:1997-03-12
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Proposal for new catalytic roles for two invariant residues in Escherichia coli ribonuclease HI.
Protein Eng., 9, 1996
1KVB
  • Download 1kvb
  • View 1kvb
Molmil generated image of 1kvb
E. COLI RIBONUCLEASE HI D134H MUTANT
Descriptor:RIBONUCLEASE H
Authors:Kashiwagi, T., Jeanteur, D., Haruki, M., Katayanagi, K., Kanaya, S., Morikawa, K.
Deposit date:1996-10-04
Release date:1997-03-12
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Proposal for new catalytic roles for two invariant residues in Escherichia coli ribonuclease HI.
Protein Eng., 9, 1996
1KVC
  • Download 1kvc
  • View 1kvc
Molmil generated image of 1kvc
E. COLI RIBONUCLEASE HI D134N MUTANT
Descriptor:RIBONUCLEASE H
Authors:Kashiwagi, T., Jeanteur, D., Haruki, M., Katayanagi, K., Kanaya, S., Morikawa, K.
Deposit date:1996-10-04
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Proposal for new catalytic roles for two invariant residues in Escherichia coli ribonuclease HI.
Protein Eng., 9, 1996