Author results

3Q3J
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CRYSTAL STRUCTURE OF PLEXIN A2 RBD IN COMPLEX WITH RND1
Descriptor:Plexin-A2, Rho-related GTP-binding protein Rho6, UNKNOWN ATOM OR ION, ...
Authors:Wang, H., Tempel, W., Tong, Y., Guan, X., Shen, L., Buren, L., Zhang, N., Wernimont, A.K., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2010-12-21
Release date:2011-01-12
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.971 Å)
Cite:Crystal structure of plexin A2 RBD in complex with Rnd1
to be published
2QNR
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HUMAN SEPTIN 2 IN COMPLEX WITH GDP
Descriptor:Septin-2, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION
Authors:Rabeh, W.M., Nedyalkova, L., Tempel, W., Landry, R., Crombet, L., Kozieradzki, I., Senisterra, G., Vedadi, M., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2007-07-19
Release date:2007-07-31
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human septin 2 in complex with GDP.
To be Published
3IEZ
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CRYSTAL STRUCTURE OF THE RASGAP C-TERMINAL (RGC) DOMAIN OF IQGAP2
Descriptor:Ras GTPase-activating-like protein IQGAP2, UNKNOWN ATOM OR ION
Authors:Nedyalkova, L., Tempel, W., Tong, Y., Zhong, N., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2009-07-23
Release date:2009-11-03
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the RasGAP C-terminal (RGC) domain of IQGAP2
To be Published
3ISU
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CRYSTAL STRUCTURE OF THE RGC DOMAIN OF IQGAP3
Descriptor:Ras GTPase-activating-like protein IQGAP3
Authors:Nedyalkova, L., Tempel, W., Tong, Y., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2009-08-27
Release date:2009-09-22
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structure of the RGC domain of IQGAP3
to be published
3L43
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CRYSTAL STRUCTURE OF THE DYNAMIN 3 GTPASE DOMAIN BOUND WITH GDP
Descriptor:Dynamin-3, GUANOSINE-5'-DIPHOSPHATE, UNKNOWN ATOM OR ION
Authors:Yang, S., Tempel, W., Tong, Y., Nedyalkova, L., Guan, X., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2009-12-18
Release date:2010-01-19
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of the dynamin 3 GTPase domain bound with GDP
to be published
3L46
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CRYSTAL STRUCTURE OF THE SECOND BRCT DOMAIN OF EPITHELIAL CELL TRANSFORMING 2 (ECT2)
Descriptor:Protein ECT2, UNKNOWN ATOM OR ION
Authors:Nedyalkova, L., Tempel, W., Tong, Y., Crombet, L., Wang, H., Guan, X., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2009-12-18
Release date:2010-01-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.482 Å)
Cite:Crystal structure of the second BRCT domain of epithelial cell transforming 2 (ECT2)
to be published
3LLU
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CRYSTAL STRUCTURE OF THE NUCLEOTIDE-BINDING DOMAIN OF RAS-RELATED GTP-BINDING PROTEIN C
Descriptor:Ras-related GTP-binding protein C, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ...
Authors:Nedyalkova, L., Tempel, W., Tong, Y., Crombet, L., Zhong, N., Guan, X., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2010-01-29
Release date:2010-02-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of the nucleotide-binding domain of Ras-related GTP-binding protein C
to be published
3MPX
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CRYSTAL STRUCTURE OF THE DH AND PH-1 DOMAINS OF HUMAN FGD5
Descriptor:FYVE, RhoGEF and PH domain-containing protein 5, UNKNOWN ATOM OR ION
Authors:Shen, Y., Nedyalkova, L., Tong, Y., Tempel, W., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2010-04-27
Release date:2010-06-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of the DH and PH-1 domains of human FGD5
TO BE PUBLISHED
3N0T
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HUMAN DIPEPTIDIL PEPTIDASE DPP7 COMPLEXED WITH INHIBITOR GSK237826A
Descriptor:Dipeptidyl peptidase 2, (3S)-4-oxo-4-piperidin-1-ylbutane-1,3-diamine
Authors:Dobrovetsky, E., Khutoreskaya, G., Seitova, A., Crombet, L., Cossar, D., Pagannon, S., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Hassell, A., Shewchuk, L., Haffner, C., Bochkarev, A., Structural Genomics Consortium (SGC)
Deposit date:2010-05-14
Release date:2010-07-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Human dipeptidyl peptidase DPP7
To be Published
3O47
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CRYSTAL STRUCTURE OF ARFGAP1-ARF1 FUSION PROTEIN
Descriptor:ADP-ribosylation factor GTPase-activating protein 1, ADP-ribosylation factor 1, ZINC ION, ...
Authors:Wang, H., Tong, Y., Nedyalkova, L., Tempel, W., Guan, X., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2010-07-26
Release date:2010-08-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of ARFGAP1-ARF1 fusion protein
to be published
3RPX
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CRYSTAL STRUCTURE OF COMPLEMENT COMPONENT 1, Q SUBCOMPONENT BINDING PROTEIN, C1QBP
Descriptor:Complement component 1 Q subcomponent-binding protein, UNKNOWN ATOM OR ION
Authors:Tempel, W., Tong, Y., Crombet, L., Shen, Y., Guan, X., Nedyalkova, L., Walker, J.R., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2011-04-27
Release date:2011-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of complement component 1, q subcomponent binding protein, C1QBP
to be published
2P0K
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CRYSTAL STRUCTURE OF SCMH1
Descriptor:Polycomb protein SCMH1, CHLORIDE ION, PHOSPHATE ION
Authors:Herzanych, N., Senisterra, G., Liu, Y., Crombet, L., Loppnau, P., Kozieradzki, I., Vedadi, M., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2007-02-28
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of SCMH1
To be Published
3KH0
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CRYSTAL STRUCTURE OF THE RAS-ASSOCIATION (RA) DOMAIN OF RALGDS
Descriptor:Ral guanine nucleotide dissociation stimulator, UNKNOWN ATOM OR ION
Authors:Shen, Y., Tempel, W., Wang, H., Tong, Y., Guan, X., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2009-10-29
Release date:2009-11-17
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the Ras-association (RA) domain of RALGDS
to be published
3KUZ
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CRYSTAL STRUCTURE OF THE UBIQUITIN LIKE DOMAIN OF PLXNC1
Descriptor:Plexin-C1, UNKNOWN ATOM OR ION
Authors:Wang, H., Li, B., Tempel, W., Tong, Y., Guan, X., Zhong, N., Crombet, L., MacKenzie, F., Buck, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2009-11-28
Release date:2009-12-08
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the ubiquitin like domain of PLXNC1
to be published
3LWE
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THE CRYSTAL STRUCTURE OF MPP8
Descriptor:M-phase phosphoprotein 8
Authors:Li, Z., Li, Z., Ruan, J., Xu, C., Tong, Y., Pan, P.W., Tempel, W., Crombet, L., Min, J., Zang, J., Structural Genomics Consortium (SGC)
Deposit date:2010-02-23
Release date:2010-03-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9.
Plos One, 6, 2011
3PFY
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THE CATALYTIC DOMAIN OF HUMAN OTUD5
Descriptor:OTU domain-containing protein 5, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL, ...
Authors:Walker, J.R., Asinas, A.E., Crombet, L., Dong, A., Weigelt, J., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2010-10-29
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:The catalytic domain of human OTUD5
To be Published
3PM8
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CAD DOMAIN OF PFF0520W, CALCIUM DEPENDENT PROTEIN KINASE
Descriptor:Calcium-dependent protein kinase 2, CALCIUM ION, SODIUM ION, ...
Authors:Wernimont, A.K., Hutchinson, A., Lew, J., Chamberlain, K., MacKenzie, F., Loppnau, P., Cossar, D., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2010-11-16
Release date:2010-12-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:CAD domain of PFF0520w, Calcium dependent protein kinase
TO BE PUBLISHED
3Q5I
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CRYSTAL STRUCTURE OF PBANKA_031420
Descriptor:Protein kinase, CALCIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Wernimont, A.K., Hutchinson, A., Sullivan, H., Panico, E., Crombet, L., Cossar, D., Hassani, A., Vedadi, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Neculai, A.M., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2010-12-28
Release date:2011-06-01
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of CDPK1 from Plasmodium Bergheii, PBANKA_031420
To be Published
3R93
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CRYSTAL STRUCTURE OF THE CHROMO DOMAIN OF M-PHASE PHOSPHOPROTEIN 8 BOUND TO H3K9ME3 PEPTIDE
Descriptor:M-phase phosphoprotein 8, H3K9Me3 peptide, UNKNOWN ATOM OR ION
Authors:Li, J., Li, Z., Ruan, J., Xu, C., Tong, Y., Pan, P.W., Tempel, W., Crombet, L., Min, J., Zang, J., Structural Genomics Consortium (SGC)
Deposit date:2011-03-24
Release date:2011-04-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.057 Å)
Cite:Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9.
Plos One, 6, 2011
3RP9
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CRYSTAL STRUCTURE OF THE APO MAPK FROM TOXOPLASMA GONDII, 25.M01780 OR TGME49_007820
Descriptor:Mitogen-activated protein kinase, SULFATE ION
Authors:Wernimont, A.K., Crombet, L., Pizarro, J.C., Crowther, G.J., Van Voorhis, W.C., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Hui, R., Lin, Y.H., Structural Genomics Consortium (SGC)
Deposit date:2011-04-26
Release date:2011-06-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the apo MapK from Toxoplasma Gondii, 25.m01780 or TGME49_007820
To be Published
3S6B
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CRYSTAL STRUCTURE OF METHIONINE AMINOPEPTIDASE 1B FROM PLASMODIUM FALCIPARUM, PF10_0150
Descriptor:Methionine aminopeptidase, GLYCEROL, FE (III) ION
Authors:Wernimont, A.K., Artz, J.D., Crombet, L., Lew, J., Weadge, J., Tempel, W., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Hui, R., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2011-05-25
Release date:2011-06-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of methionine aminopeptidase 1b from Plasmodium Falciparum, PF10_0150
To be Published
3SM9
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CRYSTAL STRUCTURE OF METABOTROPIC GLUTAMATE RECEPTOR 3 PRECURSOR IN PRESENCE OF LY341495 ANTAGONIST
Descriptor:Metabotropic glutamate receptor 3, SULFATE ION, 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, ...
Authors:Wernimont, A.K., Dong, A., Seitova, A., Crombet, L., Khutoreskaya, G., Edwards, A.M., Arrowsmith, C.H., Bountra, C., Weigelt, J., Cossar, D., Dobrovetsky, E., Structural Genomics Consortium (SGC)
Deposit date:2011-06-27
Release date:2011-07-27
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystal Structure of Metabotropic glutamate receptor 3 precursor in presence of LY341495 antagonist
TO BE PUBLISHED
3TLX
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CRYSTAL STRUCTURE OF PF10_0086, ADENYLATE KINASE FROM PLASMODIUM FALCIPARUM
Descriptor:Adenylate kinase 2, MAGNESIUM ION, ADENOSINE MONOPHOSPHATE, ...
Authors:Wernimont, A.K., Loppnau, P., Crombet, L., Weadge, J., Perieteanu, A., Edwards, A.M., Arrowsmith, C.H., Park, H., Bountra, C., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2011-08-30
Release date:2011-10-26
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal Structure of PF10_0086, adenylate kinase from plasmodium falciparum
TO BE PUBLISHED
4EZA
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CRYSTAL STRUCTURE OF THE ATYPICAL PHOSPHOINOSITIDE (API) BINDING DOMAIN OF IQGAP2
Descriptor:Ras GTPase-activating-like protein IQGAP2
Authors:Van Aalten, D.M.F., Dixon, M.J., Gray, A., Schenning, M., Agacan, M., Leslie, N.R., Downes, C.P., Batty, I.H., Nedyalkova, L., Tempel, W., Tong, Y., Zhong, N., Crombet, L., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2012-05-02
Release date:2012-05-16
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:IQGAP Proteins Reveal an Atypical Phosphoinositide (aPI) Binding Domain with a Pseudo C2 Domain Fold.
J.Biol.Chem., 287, 2012
3L11
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CRYSTAL STRUCTURE OF THE RING DOMAIN OF RNF168
Descriptor:E3 ubiquitin-protein ligase RNF168, ZINC ION, MALONATE ION
Authors:Neculai, D., Yermekbayeva, L., Crombet, L., Weigelt, J., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2009-12-10
Release date:2010-01-19
Last modified:2012-09-26
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation.
J.Biol.Chem., 287, 2012
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