6YOA
| Lig v 1 structure and the inflammatory response to the Ole e 1 protein family | Descriptor: | Major pollen allergen Lig v 1, NICKEL (II) ION | Authors: | Robledo-Retana, T, Bradley-Clark, J, Croll, T, Rose, R, Stagg, A, Villalba, M, Pickersgill, R. | Deposit date: | 2020-04-14 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Lig v 1 structure and the inflammatory response to the Ole e 1 protein family. Allergy, 75, 2020
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5UZB
| Cryo-EM structure of the MAL TIR domain filament | Descriptor: | Toll/interleukin-1 receptor domain-containing adapter protein | Authors: | Ve, T, Vajjhala, P.R, Hedger, A, Croll, T, DiMaio, F, Horsefield, S, Yu, X, Lavrencic, P, Hassan, Z, Morgan, G.P, Mansell, A, Mobli, M, O'Carrol, A, Chauvin, B, Gambin, Y, Sierecki, E, Landsberg, M.J, Stacey, K.J, Egelman, E.H, Kobe, B. | Deposit date: | 2017-02-25 | Release date: | 2017-07-26 | Last modified: | 2020-01-15 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling. Nat. Struct. Mol. Biol., 24, 2017
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7Z6M
| Crystal structure of Zn2+-transporter BbZIP in a cadmium bound state | Descriptor: | CADMIUM ION, Putative membrane protein | Authors: | Wiuf, A, Steffen, J.H, Becares, E.R, Groenberg, C, Mahato, D.R, Rasmussen, S.G.F, Andersson, M, Croll, T, Gotfryd, K, Gourdon, P. | Deposit date: | 2022-03-13 | Release date: | 2022-08-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | The two-domain elevator-type mechanism of zinc-transporting ZIP proteins. Sci Adv, 8, 2022
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7Z6N
| Crystal structure of Zn2+-transporter BbZIP in a metal-stripped state | Descriptor: | Putative membrane protein, SULFATE ION | Authors: | Wiuf, A, Steffen, J.H, Becares, E.R, Groenberg, C, Mahato, D.R, Rasmussen, S.G.F, Andersson, M, Croll, T, Gotfryd, K, Gourdon, P. | Deposit date: | 2022-03-13 | Release date: | 2022-08-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | The two-domain elevator-type mechanism of zinc-transporting ZIP proteins. Sci Adv, 8, 2022
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7FII
| luteinizing hormone/choriogonadotropin receptor-chorionic gonadotropin-Gs complex | Descriptor: | Choriogonadotropin subunit beta 3, Engineered Guanine nucleotide-binding protein G(s) subunit alpha, Glycoprotein hormones alpha chain, ... | Authors: | Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E. | Deposit date: | 2021-07-31 | Release date: | 2021-09-29 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structures of full-length glycoprotein hormone receptor signalling complexes. Nature, 598, 2021
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7FIJ
| luteinizing hormone/choriogonadotropin receptor | Descriptor: | Lutropin-choriogonadotropic hormone receptor | Authors: | Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E. | Deposit date: | 2021-07-31 | Release date: | 2021-09-29 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of full-length glycoprotein hormone receptor signalling complexes. Nature, 598, 2021
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7FIG
| luteinizing hormone/choriogonadotropin receptor(S277I)-chorionic gonadotropin-Gs complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Camelid antibody VHH fragment Nb35, Choriogonadotropin subunit beta 3, ... | Authors: | Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E. | Deposit date: | 2021-07-31 | Release date: | 2021-09-29 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structures of full-length glycoprotein hormone receptor signalling complexes. Nature, 598, 2021
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7FIH
| luteinizing hormone/choriogonadotropin receptor(S277I)-chorionic gonadotropin-Gs-Org43553 complex | Descriptor: | 5-azanyl-N-tert-butyl-2-methylsulfanyl-4-[3-(2-morpholin-4-ylethanoylamino)phenyl]thieno[2,3-d]pyrimidine-6-carboxamide, Choriogonadotropin subunit beta 3, Engineered Guanine nucleotide-binding protein G(s) subunit alpha, ... | Authors: | Duan, J, Xu, P, Cheng, X, Mao, C, Croll, T, He, X, Shi, J, Luan, X, Yin, W, You, E, Liu, Q, Zhang, S, Jiang, H, Zhang, Y, Jiang, Y, Xu, H.E. | Deposit date: | 2021-07-31 | Release date: | 2021-09-29 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of full-length glycoprotein hormone receptor signalling complexes. Nature, 598, 2021
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4ZXB
| Structure of the human insulin receptor ectodomain, IRDeltabeta construct, in complex with four Fab molecules | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Croll, T, Smith, B.J, Margetts, M.B, Whittaker, J, Weiss, M.A, Ward, C.W, Lawrence, M.C. | Deposit date: | 2015-05-20 | Release date: | 2016-02-24 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain. Structure, 24, 2016
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5KSD
| Crystal Structure of a Plasma Membrane Proton Pump | Descriptor: | ATPase 2, plasma membrane-type, DODECYL-BETA-D-MALTOSIDE, ... | Authors: | Croll, T, Pedersen, B.P, Nissen, P. | Deposit date: | 2016-07-08 | Release date: | 2016-08-10 | Last modified: | 2017-05-17 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Improved Model of Proton Pump Crystal Structure Obtained by Interactive Molecular Dynamics Flexible Fitting Expands the Mechanistic Model for Proton Translocation in P-Type ATPases. Front Physiol, 8, 2017
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5TEB
| Crystal Structure of the TIR domain from the Arabidopsis Thaliana disease resistance protein RPP1 | Descriptor: | Recognition of Peronospora parasitica 1 | Authors: | Bentham, A.R, Zhang, X, Croll, T, Williams, S, Kobe, B. | Deposit date: | 2016-09-20 | Release date: | 2017-02-01 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2.796 Å) | Cite: | Multiple functional self-association interfaces in plant TIR domains. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2NCG
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6U9D
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6WO1
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6U9H
| Arabidopsis thaliana acetohydroxyacid synthase complex | Descriptor: | Acetolactate synthase small subunit 2, chloroplastic, Acetolactate synthase, ... | Authors: | Guddat, L.W, Low, Y.S, Rao, Z. | Deposit date: | 2019-09-08 | Release date: | 2020-07-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of fungal and plant acetohydroxyacid synthases. Nature, 586, 2020
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6VZ8
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8CKP
| X-ray structure of the crystallization-prone form of subfamily III haloalkane dehalogenase DhmeA from Haloferax mediterranei | Descriptor: | Alpha/beta fold hydrolase, CHLORIDE ION | Authors: | Marek, M, Chmelova, K, Schenkmayerova, A, Croll, T, Read, R.J, Diederichs, K. | Deposit date: | 2023-02-16 | Release date: | 2023-08-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Multimeric structure of a subfamily III haloalkane dehalogenase-like enzyme solved by combination of cryo-EM and x-ray crystallography. Protein Sci., 32, 2023
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6BNJ
| Human hypoxanthine guanine phosphoribosyltransferase in complex with [3R,4R]-4-guanin-9-yl-3-((R)-2-hydroxy-2-phosphonoethyl)oxy-1-N-(phosphonopropionyl)pyrrolidine | Descriptor: | (3-{(3R,4R)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-[(2R)-2-hydroxy-2-phosphonoethoxy]pyrrolidin-1-yl}-3-oxopropy l)phosphonic acid, Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION | Authors: | Keough, D.T, Rejman, D, Guddat, L.W. | Deposit date: | 2017-11-16 | Release date: | 2017-12-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.909 Å) | Cite: | Design of Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitors as Potential Antimalarial Therapeutics. ACS Chem. Biol., 13, 2018
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6BO7
| Crystal structure of Plasmodium vivax hypoxanthine guanine phosphoribosyltransferase in complex with [3R,4R]-4-guanin-9-yl-3-((S)-2-hydroxy-2-phosphonoethyl)oxy-1-N-(phosphonopropionyl)pyrrolidine | Descriptor: | Hypoxanthine phosphoribosyltransferase, MAGNESIUM ION, [3-[(3~{R},4~{R})-3-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-[(2~{S})-2-oxidanyl-2-phosphono-ethoxy]pyrrolidin-1-y l]-3-oxidanylidene-propyl]phosphonic acid | Authors: | Guddat, L.W, Keough, D.T, Rejman, D. | Deposit date: | 2017-11-18 | Release date: | 2017-12-13 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.856 Å) | Cite: | Design of Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitors as Potential Antimalarial Therapeutics. ACS Chem. Biol., 13, 2018
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5HIA
| Human hypoxanthine-guanine phosphoribosyltransferase in complex with [3R,4R]-4-guanin-9-yl-3-((S)-2-hydroxy-2-phosphonoethyl)oxy-1-N-(phosphonopropionyl)pyrrolidine | Descriptor: | Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION, [3-[(3~{R},4~{R})-3-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-[(2~{S})-2-oxidanyl-2-phosphono-ethoxy]pyrrolidin-1-y l]-3-oxidanylidene-propyl]phosphonic acid | Authors: | Guddat, L.W, Keough, D.T, Rejman, D. | Deposit date: | 2016-01-11 | Release date: | 2017-01-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.773 Å) | Cite: | Design of Plasmodium vivax Hypoxanthine-Guanine Phosphoribosyltransferase Inhibitors as Potential Antimalarial Therapeutics. ACS Chem. Biol., 2017
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5T1Y
| MLA10 coiled-coil fragment | Descriptor: | MLA10, TRIETHYLENE GLYCOL | Authors: | Williams, S.J, Kobe, B, Bentham, A, Ericsson, D.J. | Deposit date: | 2016-08-22 | Release date: | 2016-11-02 | Last modified: | 2016-11-23 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The CC domain structure from the wheat stem rust resistance protein Sr33 challenges paradigms for dimerization in plant NLR proteins. Proc.Natl.Acad.Sci.USA, 2016
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7EMY
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7EN1
| Pyochelin synthetase, a dimeric nonribosomal peptide synthetase elongation module-after-condensation | Descriptor: | (4S)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid, 2-HYDROXYBENZOIC ACID, 4'-PHOSPHOPANTETHEINE, ... | Authors: | Wang, J.L, Wang, Z.J. | Deposit date: | 2021-04-15 | Release date: | 2021-12-22 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Catalytic trajectory of a dimeric nonribosomal peptide synthetase subunit with an inserted epimerase domain. Nat Commun, 13, 2022
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7EN2
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7QBZ
| Crystal structure Cadmium translocating P-type ATPase | Descriptor: | Cadmium translocating P-type ATPase, MAGNESIUM ION, TETRAFLUOROALUMINATE ION | Authors: | Groenberg, C, Hu, Q, Wang, K, Gourdon, P. | Deposit date: | 2021-11-21 | Release date: | 2022-03-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structure and ion-release mechanism of P IB-4 -type ATPases. Elife, 10, 2021
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