Author results

2XGT
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ASPARAGINYL-TRNA SYNTHETASE FROM BRUGIA MALAYI COMPLEXED WITH THE SULPHAMOYL ANALOGUE OF ASPARAGINYL-ADENYLATE
分子名称:ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC, GLYCEROL, ...
著者Crepin, T., Haertlein, M., Kron, M., Cusack, S.
登録日2010-06-07
公開日2010-12-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Hybrid Structural Model of the Complete Brugia Malayi Cytoplasmic Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 405, 2011
2XTI
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ASPARAGINYL-TRNA SYNTHETASE FROM BRUGIA MALAYI COMPLEXED WITH ATP:MG AND L-ASP-BETA-NOH ADENYLATE:PPI:MG
分子名称:ASPARAGINYL-TRNA SYNTHETASE\, CYTOPLASMIC\, PUTATIVE, ...
著者Crepin, T., Haertlein, M., Kron, M., Cusack, S.
登録日2010-10-10
公開日2010-12-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Hybrid Structural Model of the Complete Brugia Malayi Cytoplasmic Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 405, 2011
1MKH
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C-TERMINAL DOMAIN OF METHIONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI
分子名称:C-terminal domain of Methionyl-tRNA synthetase
著者Crepin, T., Schmitt, E., Blanquet, S., Mechulam, Y.
登録日2002-08-29
公開日2003-02-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structure and function of the C-terminal domain of methionyl-tRNA synthetase
Biochemistry, 41, 2002
1P7P
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METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH METHIONINE PHOSPHONATE
分子名称:Methionyl-tRNA synthetase, ZINC ION, (1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHONIC ACID
著者Crepin, T., Schmitt, E., Mechulam, Y., Sampson, P.B., Vaughan, M.D., Honek, J.F., Blanquet, S.
登録日2003-05-05
公開日2004-02-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.
J.Mol.Biol., 332, 2003
1PFU
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METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH METHIONINE PHOSPHINATE
分子名称:Methionyl-tRNA synthetase, ZINC ION, (1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC ACID
著者Crepin, T., Schmitt, E., Mechulam, Y., Sampson, P.B., Vaughan, M.D., Honek, J.F., Blanquet, S.
登録日2003-05-27
公開日2004-02-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.
J.Mol.Biol., 332, 2003
1PFV
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METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH DIFLUOROMETHIONINE
分子名称:Methionyl-tRNA synthetase, ZINC ION, S-(DIFLUOROMETHYL)HOMOCYSTEINE
著者Crepin, T., Schmitt, E., Mechulam, Y., Sampson, P.B., Vaughan, M.D., Honek, J.F., Blanquet, S.
登録日2003-05-27
公開日2004-02-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.
J.Mol.Biol., 332, 2003
1PFW
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METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH TRIFLUOROMETHIONINE
分子名称:Methionyl-tRNA synthetase, ZINC ION, 2-AMINO-4-TRIFLUOROMETHYLSULFANYL-BUTYRIC ACID
著者Crepin, T., Schmitt, E., Mechulam, Y., Sampson, P.B., Vaughan, M.D., Honek, J.F., Blanquet, S.
登録日2003-05-27
公開日2004-02-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.
J.Mol.Biol., 332, 2003
1PFY
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METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH METHIONYL SULPHAMOYL ADENOSINE
分子名称:Methionyl-tRNA synthetase, ZINC ION, 5'-O-[(L-METHIONYL)-SULPHAMOYL]ADENOSINE
著者Crepin, T., Schmitt, E., Mechulam, Y., Sampson, P.B., Vaughan, M.D., Honek, J.F., Blanquet, S.
登録日2003-05-27
公開日2004-02-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.
J.Mol.Biol., 332, 2003
1PG0
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METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH METHIONINYL ADENYLATE
分子名称:Methionyl-tRNA synthetase, L-METHIONYL ADENYLATE
著者Crepin, T., Schmitt, E., Mechulam, Y., Sampson, P.B., Vaughan, M.D., Honek, J.F., Blanquet, S.
登録日2003-05-27
公開日2004-02-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.
J.Mol.Biol., 332, 2003
1PG2
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METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH METHIONINE AND ADENOSINE
分子名称:Methionyl-tRNA synthetase, ADENOSINE, METHIONINE
著者Crepin, T., Schmitt, E., Mechulam, Y., Sampson, P.B., Vaughan, M.D., Honek, J.F., Blanquet, S.
登録日2003-05-27
公開日2004-02-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase.
J.Mol.Biol., 332, 2003
1RQG
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METHIONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI
分子名称:Methionyl-tRNA synthetase, ZINC ION
著者Crepin, T., Schmitt, E., Blanquet, S., Mechulam, Y.
登録日2003-12-05
公開日2004-05-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Three-dimensional structure of methionyl-tRNA synthetase from Pyrococcus abyssi.
Biochemistry, 43, 2004
2I4L
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RHODOPSEUDOMONAS PALUSTRIS PROLYL-TRNA SYNTHETASE
分子名称:Proline-tRNA ligase
著者Crepin, T., Yaremchuk, A., Tukalo, M., Cusack, S.
登録日2006-08-22
公開日2006-10-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
2I4M
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RHODOPSEUDOMONAS PALUSTRIS PROLYL-TRNA SYNTHETASE IN COMPLEX WITH PROAMS
分子名称:Proline-tRNA ligase, 5'-O-[N-(PROLYL)-SULFAMOYL]ADENOSINE
著者Crepin, T., Yaremchuk, A., Tukalo, M., Cusack, S.
登録日2006-08-22
公開日2006-10-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
2I4N
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RHODOPSEUDOMONAS PALUSTRIS PROLYL-TRNA SYNTHETASE IN COMPLEX WITH CYSAMS
分子名称:Proline-tRNA ligase, 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE
著者Crepin, T., Yaremchuk, A., Tukalo, M., Cusack, S.
登録日2006-08-22
公開日2006-10-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
2I4O
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RHODOPSEUDOMONAS PALUSTRIS PROLYL-TRNA SYNTHETASE IN COMPLEX WITH ATP
分子名称:Proline-tRNA ligase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
著者Crepin, T., Yaremchuk, A., Tukalo, M., Cusack, S.
登録日2006-08-22
公開日2006-10-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
2J3L
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PROLYL-TRNA SYNTHETASE FROM ENTEROCOCCUS FAECALIS COMPLEXED WITH A PROLYL-ADENYLATE ANALOGUE ('5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE)
分子名称:PROLYL-TRNA SYNTHETASE, SULFATE ION, '5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE
著者Crepin, T., Yaremchuk, A., Tukalo, M., Cusack, S.
登録日2006-08-22
公開日2006-10-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a Cis-Editing Domain.
Structure, 14, 2006
2J3M
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PROLYL-TRNA SYNTHETASE FROM ENTEROCOCCUS FAECALIS COMPLEXED WITH ATP, MANGANESE AND PROLINOL
分子名称:PROLYL-TRNA SYNTHETASE, ADENOSINE-5'-TRIPHOSPHATE, PYRROLIDINE-2-CARBALDEHYDE, ...
著者Crepin, T., Yaremchuk, A., Tukalo, M., Cusack, S.
登録日2006-08-22
公開日2006-10-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a Cis-Editing Domain.
Structure, 14, 2006
4C0S
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MAMMALIAN TRANSLATION ELONGATION FACTOR EEF1A2
分子名称:ELONGATION FACTOR 1-ALPHA 2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Crepin, T., Shalak, V.F., Yaremchuk, A.D., Vlasenko, D.O., McCarthy, A.A., Negrutskii, B.S., Tukalo, M.A., El'skaya, A.V.
登録日2013-08-07
公開日2014-08-27
最終更新日2017-01-25
実験手法X-RAY DIFFRACTION (2.703 Å)
主引用文献Mammalian Translation Elongation Factor Eef1A2: X-Ray Structure and New Features of Gdp/GTP Exchange Mechanism in Higher Eukaryotes
Nucleic Acids Res., 42, 2014
2V0C
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LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A SULPHAMOYL ANALOGUE OF LEUCYL-ADENYLATE IN THE SYNTHETIC SITE AND AN ADDUCT OF AMP WITH 5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE (AN2690) IN THE EDITING SITE
分子名称:AMINOACYL-TRNA SYNTHETASE, LEUCINE, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDRO-2-FURANYL]METHYL SULFAMATE, ...
著者Rock, F., Mao, W., Yaremchuk, A., Tukalo, M., Crepin, T., Zhou, H., Zhang, Y., Hernandez, V., Akama, T., Baker, S., Plattner, J., Shapiro, L., Martinis, S.A., Benkovic, S.J., Cusack, S., Alley, M.R.K.
登録日2007-05-14
公開日2007-07-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site.
Science, 316, 2007
2V0G
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LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A TRNA(LEU) TRANSCRIPT WITH 5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1- BENZOXABOROLE (AN2690) FORMING AN ADDUCT TO THE RIBOSE OF ADENOSINE- 76 IN THE ENZYME EDITING SITE.
分子名称:AMINOACYL-TRNA SYNTHETASE, TRNALEU, LEUCINE, ...
著者Rock, F., Mao, W., Yaremchuk, A., Tukalo, M., Crepin, T., Zhou, H., Zhang, Y., Hernandez, V., Akama, T., Baker, S., Plattner, J., Shapiro, L., Martinis, S.A., Benkovic, S.J., Cusack, S., Alley, M.R.K.
登録日2007-05-14
公開日2007-07-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site.
Science, 316, 2007
3ZJT
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TERNARY COMPLEX OF E.COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU)574 AND THE BENZOXABOROLE AN3017 IN THE EDITING CONFORMATION
分子名称:LEUCYL-TRNA SYNTHETASE, TRNALEU5 UAA ISOACCEPTOR, MAGNESIUM ION
著者Cusack, S., Palencia, A., Crepin, T., Hernandez, V., Akama, T., Baker, S.J., Bu, W., Feng, L., Freund, Y.R., Liu, L., Meewan, M., Mohan, M., Mao, W., Rock, F.L., Sexton, H., Sheoran, A., Zhang, Y., Zhang, Y., Zhou, Y., Nieman, J.A., Anugula, M.R., Keramane, E.M., Savariraj, K., Reddy, D.S., Sharma, R., Subedi, R., Singh, R., OLeary, A., Simon, N.L., DeMarsh, P.L., Mushtaq, S., Warner, M., Livermore, D.M., Alley, M.R.K., Plattner, J.J.
登録日2013-01-18
公開日2013-04-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria.
Antimicrob.Agents Chemother., 57, 2013
3ZJU
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TERNARY COMPLEX OF E .COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) AND THE BENZOXABOROLE AN3016 IN THE EDITING CONFORMATION
分子名称:LEUCYL-TRNA SYNTHETASE, TRNALEU5 UAA ISOACCEPTOR, MAGNESIUM ION
著者Cusack, S., Palencia, A., Crepin, T., Hernandez, V., Akama, T., Baker, S.J., Bu, W., Feng, L., Freund, Y.R., Liu, L., Meewan, M., Mohan, M., Mao, W., Rock, F.L., Sexton, H., Sheoran, A., Zhang, Y., Zhang, Y., Zhou, Y., Nieman, J.A., Anugula, M.R., Keramane, E.M., Savariraj, K., Reddy, D.S., Sharma, R., Subedi, R., Singh, R., OLeary, A., Simon, N.L., DeMarsh, P.L., Mushtaq, S., Warner, M., Livermore, D.M., Alley, M.R.K., Plattner, J.J.
登録日2013-01-18
公開日2013-04-17
最終更新日2018-10-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria.
Antimicrob.Agents Chemother., 57, 2013
3ZJV
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TERNARY COMPLEX OF E .COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) AND THE BENZOXABOROLE AN3213 IN THE EDITING CONFORMATION
分子名称:LEUCINE--TRNA LIGASE, TRNALEU5 UAA ISOACCEPTOR
著者Cusack, S., Palencia, A., Crepin, T., Hernandez, V., Akama, T., Baker, S.J., Bu, W., Feng, L., Freund, Y.R., Liu, L., Meewan, M., Mohan, M., Mao, W., Rock, F.L., Sexton, H., Sheoran, A., Zhang, Y., Zhang, Y., Zhou, Y., Nieman, J.A., Anugula, M.R., Keramane, E.M., Savariraj, K., Reddy, D.S., Sharma, R., Subedi, R., Singh, R., OLeary, A., Simon, N.L., DeMarsh, P.L., Mushtaq, S., Warner, M., Livermore, D.M., Alley, M.R.K., Plattner, J.J.
登録日2013-01-18
公開日2013-04-17
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria.
Antimicrob.Agents Chemother., 57, 2013
4CGS
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF THE PA SUBUNIT OF DHORI VIRUS POLYMERASE
分子名称:POLYMERASE SUBUNIT PA, GLYCEROL
著者Guilligay, D., Kadlec, J., Crepin, T., Lunardi, T., Bouvier, D., Kochs, G., Ruigrok, R.W.H., Cusack, S.
登録日2013-11-26
公開日2014-02-05
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
4CGX
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF THE PA SUBUNIT OF THOGOTO VIRUS POLYMERASE (FORM 1)
分子名称:POLYMERASE ACIDIC PROTEIN
著者Guilligay, D., Kadlec, J., Crepin, T., Lunardi, T., Bouvier, D., Kochs, G., Ruigrok, R.W.H., Cusack, S.
登録日2013-11-27
公開日2014-02-05
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains.
Plos One, 9, 2014
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