Author results

2Y37
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THE DISCOVERY OF NOVEL, POTENT AND HIGHLY SELECTIVE INHIBITORS OF INDUCIBLE NITRIC OXIDE SYNTHASE (INOS)
分子名称:NITRIC OXIDE SYNTHASE, INDUCIBLE, SULFATE ION, ...
著者Cheshire, D.R., Andrews, G., Beaton, H.G., Birkinshaw, T.N., Boughton-Smith, N., Connolly, S., Cook, T.R., Cooper, A., Cooper, S.L., Cox, D., Dixon, J., Gensmantel, N., Hamley, P.J., Harrison, R., Hartopp, P., Kack, H., Luker, T., Mete, A., Millichip, I., Nicholls, D.J., Pimm, A.D., St-Gallay, S.A., Wallace, A.V.
登録日2010-12-19
公開日2011-04-13
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos).
Bioorg.Med.Chem.Lett., 21, 2011
4UX6
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THE DISCOVERY OF NOVEL, POTENT AND HIGHLY SELECTIVE INHIBITORS OF INDUCIBLE NITRIC OXIDE SYNTHASE (INOS)
分子名称:NITRIC OXIDE SYNTHASE, INDUCIBLE, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Cheshire, D.R., Andrews, G., Beaton, H.G., Birkinshaw, T., Boughton-Smith, N., Connolly, S., Cook, T.R., Cooper, A., Cooper, S.L., Cox, D., Dixon, J., Gensmantel, N., Hamley, P.J., Harrison, R., Hartopp, P., Kack, H., Luker, T., Mete, A., Millichip, I., Nicholls, D.J., Pimm, A.D., St-Gallay, S.A., Wallace, A.V.
登録日2014-08-19
公開日2014-10-08
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos).
Bioorg.Med.Chem.Lett., 21, 2011
5JH7
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TUBULIN-ERIBULIN COMPLEX
分子名称:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
著者Doodhi, H., Prota, A.E., Rodriguez-Garcia, R., Xiao, H., Custar, D.W., Bargsten, K., Katrukha, E.A., Hilbert, M., Hua, S., Jiang, K., Grigoriev, I., Yang, C.-P.H., Cox, D., Band Horwitz, S., Kapitein, L.C., Akhmanova, A., Steinmetz, M.O.
登録日2016-04-20
公開日2016-06-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes.
Curr.Biol., 26, 2016
4R36
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CRYSTAL STRUCTURE ANALYSIS OF LPXA, A UDP-N-ACETYLGLUCOSAMINE ACYLTRANSFERASE FROM BACTEROIDES FRAGILIS 9343
分子名称:Putative acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, 2-(2-METHOXYETHOXY)ETHANOL, ACETATE ION, ...
著者Ngo, A., Fong, K., Cox, D., Fisher, A., Chen, X.
登録日2014-08-14
公開日2015-05-06
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of Bacteroides fragilis uridine 5'-diphosphate-N-acetylglucosamine (UDP-GlcNAc) acyltransferase (BfLpxA).
Acta Crystallogr.,Sect.D, 71, 2015
1D5M
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X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH PEPTIDE AND SEB
分子名称:HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ENTEROTOXIN TYPE B, INHIBITOR, ...
著者Swain, A.L., Crowther, R., Kammlott, U.
登録日1999-10-07
公開日2000-06-28
最終更新日2018-10-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Peptide and peptide mimetic inhibitors of antigen presentation by HLA-DR class II MHC molecules. Design, structure-activity relationships, and X-ray crystal structures.
J.Med.Chem., 43, 2000
1D5X
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X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH DIPEPTIDE MIMETIC AND SEB
分子名称:HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ENTEROTOXIN TYPE B, DIPEPTIDE MIMETIC INHIBITOR
著者Swain, A., Crowther, R., Kammlott, U.
登録日1999-10-12
公開日2000-06-28
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Peptide and peptide mimetic inhibitors of antigen presentation by HLA-DR class II MHC molecules. Design, structure-activity relationships, and X-ray crystal structures.
J.Med.Chem., 43, 2000
1D5Z
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X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH PEPTIDOMIMETIC AND SEB
分子名称:PROTEIN (HLA CLASS II HISTOCOMPATIBILITY ANTIGEN), PROTEIN (ENTEROTOXIN TYPE B), PROTEIN (PEPTIDOMIMETIC INHIBITOR)
著者Swain, A., Crowther, R., Kammlott, U.
登録日1999-10-12
公開日2000-06-28
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Peptide and peptide mimetic inhibitors of antigen presentation by HLA-DR class II MHC molecules. Design, structure-activity relationships, and X-ray crystal structures.
J.Med.Chem., 43, 2000
1D6E
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CRYSTAL STRUCTURE OF HLA-DR4 COMPLEX WITH PEPTIDOMIMETIC AND SEB
分子名称:HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ENTEROTOXIN TYPE B, PEPTIDOMIMETIC INHIBITOR
著者Swain, A., Crowther, R., Kammlott, U.
登録日1999-10-13
公開日2000-06-28
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Peptide and peptide mimetic inhibitors of antigen presentation by HLA-DR class II MHC molecules. Design, structure-activity relationships, and X-ray crystal structures.
J.Med.Chem., 43, 2000
4M5S
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HUMAN ALPHAB CRYSTALLIN CORE DOMAIN IN COMPLEX WITH C-TERMINAL PEPTIDE
分子名称:Alpha-crystallin B chain, SUCCINIC ACID
著者Laganowsky, A., Cascio, D., Sawaya, M.R., Eisenberg, D.
登録日2013-08-08
公開日2014-04-09
最終更新日2014-05-14
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity.
Proc.Natl.Acad.Sci.USA, 111, 2014
4M5T
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DISULFIDE TRAPPED HUMAN ALPHAB CRYSTALLIN CORE DOMAIN IN COMPLEX WITH C-TERMINAL PEPTIDE
分子名称:Alpha-crystallin B chain, SULFATE ION
著者Laganowsky, A., Cascio, D., Hochberg, G., Sawaya, M.R., Benesch, J.L.P., Robinson, C.V., Eisenberg, D.
登録日2013-08-08
公開日2014-04-09
最終更新日2014-05-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity.
Proc.Natl.Acad.Sci.USA, 111, 2014
4MJH
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HUMAN HSP27 CORE DOMAIN IN COMPLEX WITH C-TERMINAL PEPTIDE
分子名称:Heat shock protein beta-1
著者Laganowsky, A., Cascio, D., Sawaya, M.R., Eisenberg, D.
登録日2013-09-03
公開日2014-04-09
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.599 Å)
主引用文献The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity.
Proc.Natl.Acad.Sci.USA, 111, 2014