Author results

2FVN
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THE FIBRILLAR TIP COMPLEX OF THE AFA/DR ADHESINS FROM PATHOGEN E. COLI DISPLAYS SYNERGISTIC BINDING TO 5 1 AND V 3 INTEGRINS
Descriptor:Protein afaD
Authors:Cota, E., Simpson, P., Anderson, K.L., Matthews, S.J.
Deposit date:2006-01-31
Release date:2007-02-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of the invasive tip complex from Afa/Dr fibrils
Mol.Microbiol., 62, 2006
2IXQ
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THE SOLUTION STRUCTURE OF THE INVASIVE TIP COMPLEX FROM AFA-DR FIBRILS
Descriptor:Protein AfaD, Afimbrial adhesin AFA-III
Authors:Cota, E., Jones, C., Simpson, P., Altroff, H., Anderson, K.L., du Merle, L., Guignot, J., Servin, A., Le Bouguenec, C., Mardon, H., Matthews, S.
Deposit date:2006-07-10
Release date:2006-09-20
Last modified:2018-12-05
Method:SOLUTION NMR
Cite:The solution structure of the invasive tip complex from Afa/Dr fibrils.
Mol. Microbiol., 62, 2006
1USQ
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COMPLEX OF E. COLI DRAE ADHESIN WITH CHLORAMPHENICOL
Descriptor:DR HEMAGGLUTININ STRUCTURAL SUBUNIT, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Anderson, K.L., Billington, J., Pettigrew, D., Cota, E., Roversi, P., Simpson, P., Chen, H.A., Urvil, P., Dumerle, L., Barlow, P., Medof, E., Smith, R.A.G., Nowicki, B., Le Bouguenec, C., Lea, S.M., Matthews, S.
Deposit date:2003-11-27
Release date:2004-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:High Resolution Studies of the Afa/Dr Adhesin Drae and its Interaction with Chloramphenicol
J.Biol.Chem., 279, 2004
1USZ
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SEMET AFAE-3 ADHESIN FROM ESCHERICHIA COLI
Descriptor:AFIMBRIAL ADHESIN AFA-III, SULFATE ION, CHLORIDE ION
Authors:Anderson, K.L., Billington, J., Pettigrew, D., Cota, E., Roversi, P., Simpson, P., Chen, H.A., Urvil, P., Dumerle, L., Barlow, P., Medof, E., Smith, R.A.G., Nowicki, B., Le Bouguenec, C., Lea, S.M., Matthews, S.
Deposit date:2003-12-02
Release date:2004-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.28 Å)
Cite:High Resolution Studies of the Afa/Dr Adhesin Drae and its Interaction with Chloramphenicol
J.Biol.Chem., 279, 2004
1UT1
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DRAE ADHESIN FROM ESCHERICHIA COLI
Descriptor:DR HEMAGGLUTININ STRUCTURAL SUBUNIT, SULFATE ION, 1,2-ETHANEDIOL
Authors:Anderson, K.L., Billington, J., Pettigrew, D., Cota, E., Roversi, P., Simpson, P., Chen, H.A., Urvil, P., Dumerle, L., Barlow, P., Medof, E., Smith, R.A.G., Nowicki, B., Le Bouguenec, C., Lea, S.M., Matthews, S.
Deposit date:2003-12-02
Release date:2004-08-31
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:High Resolution Studies of the Afa/Dr Adhesin Drae and its Interaction with Chloramphenicol
J.Biol.Chem., 279, 2004
1UT2
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AFAE-3 ADHESIN FROM ESCHERICHIA COLI
Descriptor:AFIMBRIAL ADHESIN AFA-III, SULFATE ION
Authors:Anderson, K.L., Billington, J., Pettigrew, D., Cota, E., Roversi, P., Simpson, P., Chen, H.A., Urvil, P., Dumerle, L., Barlow, P., Medof, E., Smith, R.A.G., Nowicki, B., Le Bouguenec, C., Lea, S.M., Matthews, S.
Deposit date:2003-12-02
Release date:2004-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:High Resolution Studies of the Afa/Dr Adhesin Drae and its Interaction with Chloramphenicol
J.Biol.Chem., 279, 2004
2Y2T
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E. COLI CSGC IN REDUCED FORM
Descriptor:CURLI PRODUCTION PROTEIN CSGC
Authors:Taylor, J.D., Salgado, P.S., Cota, E., Matthews, S.J.
Deposit date:2010-12-16
Release date:2011-09-21
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Atomic Resolution Insights Into Curli Fiber Biogenesis.
Structure, 19, 2011
2Y2Y
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OXIDISED FORM OF E. COLI CSGC
Descriptor:CURLI PRODUCTION PROTEIN CSGC, ACETATE ION
Authors:Taylor, J.D., Salgado, P.S., Constable, S.C., Cota, E., Mathews, S.J.
Deposit date:2010-12-16
Release date:2011-09-21
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Atomic Resolution Insights Into Curli Fiber Biogenesis.
Structure, 19, 2011
2XSK
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E. COLI CURLI PROTEIN CSGC - SECYS
Descriptor:CSGC, ACETATE ION
Authors:Salgado, P.S., Taylor, J.D., Cota, E., Matthews, S.J.
Deposit date:2010-09-29
Release date:2010-12-29
Last modified:2014-01-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Extending the Usability of the Phasing Power of Diselenide Bonds: Secys Sad Phasing of Csgc Using a Non-Auxotrophic Strain.
Acta Crystallogr.,Sect.D, 67, 2011
1RXL
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SOLUTION STRUCTURE OF THE ENGINEERED PROTEIN AFAE-DSC
Descriptor:Afimbrial adhesin AFA-III
Authors:Anderson, K.L., Billington, J., Pettigrew, D., Cota, E., Roversi, P., Simpson, P., Chen, H.A., Urvil, P., du Merle, L., Barlow, P.N., Medof, M.E., Smith, R.A., Nowicki, B., Le Bouguenec, C., Lea, S.M., Matthews, S.
Deposit date:2003-12-18
Release date:2005-01-11
Last modified:2017-02-08
Method:SOLUTION NMR
Cite:An atomic resolution model for assembly, architecture, and function of the Dr adhesins.
Mol.Cell, 15, 2004
2BVB
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THE C-TERMINAL DOMAIN FROM MICRONEMAL PROTEIN 1 (MIC1) FROM TOXOPLASMA GONDII
Descriptor:MICRONEMAL PROTEIN 1
Authors:Saouros, S., Edwards-Jones, B., Reiss, M., Sawmynaden, K., Cota, E., Simpson, P., Dowse, T.J., Jakle, U., Ramboarina, S., Shivarattan, T., Matthews, S., Soldati-Favre, D.
Deposit date:2005-06-23
Release date:2005-10-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A Novel Galectin-Like Domain from Toxoplasma Gondll Micronemal Protein 1 Assists the Folding, Assembly,and Transport of a Cell-Adhesion Complex.
J.Biol.Chem., 280, 2005
2MPV
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STRUCTURAL INSIGHT INTO HOST RECOGNITION AND BIOFILM FORMATION BY AGGREGATIVE ADHERENCE FIMBRIAE OF ENTEROAGGREGATIVE ESHERICHIA COLI
Descriptor:Major fimbrial subunit of aggregative adherence fimbria II AafA
Authors:Matthews, S.J., Yang, Y., Berry, A.A., Pakharukova, N., Garnett, J.A., Lee, W., Cota, E., Liu, B., Roy, S., Tuittila, M., Marchant, J., Inman, K.G., Ruiz-Perez, F., Mandomando, I., Nataro, J.P., Zavialov, A.V.
Deposit date:2014-06-04
Release date:2014-10-29
Method:SOLUTION NMR
Cite:Structural insight into host recognition by aggregative adherence fimbriae of enteroaggregative Escherichia coli.
Plos Pathog., 10, 2014
2VER
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STRUCTURAL MODEL FOR THE COMPLEX BETWEEN THE DR ADHESINS AND CARCINOEMBRYONIC ANTIGEN (CEA)
Descriptor:AFIMBRIAL ADHESIN AFA-III, ARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 5, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate
Authors:Korotkova, N., Yang, Y., Le Trong, I., Cota, E., Demeler, B., Marchant, J., Thomas, W.E., Stenkamp, R.E., Moseley, S.L., Matthews, S.
Deposit date:2007-10-26
Release date:2008-01-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Binding of Dr Adhesins of Escherichia Coli to Carcinoembryonic Antigen Triggers Receptor Dissociation.
Mol.Microbiol., 67, 2008
2WNM
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SOLUTION STRUCTURE OF GP2
Descriptor:GENE 2
Authors:Camara, B., Liu, M., Shadrinc, A., Liu, B., Simpson, P., Weinzierl, R., Severinovc, K., Cota, E., Matthews, S., Wigneshweraraj, S.R.
Deposit date:2009-07-13
Release date:2010-02-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:T7 Phage Protein Gp2 Inhibits the Escherichia Coli RNA Polymerase by Antagonizing Stable DNA Strand Separation Near the Transcription Start Site.
Proc.Natl.Acad.Sci.USA, 107, 2010
2Y7L
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STRUCTURE OF N-TERMINAL DOMAIN OF CANDIDA ALBICANS ALS9-2 IN COMPLEX WITH HUMAN FIBRINOGEN GAMMA PEPTIDE
Descriptor:AGGLUTININ-LIKE ALS9 PROTEIN, FIBRINOGEN GAMMA CHAIN, ISOFORM CRA_A
Authors:Salgado, P.S., Cota, E.
Deposit date:2011-01-31
Release date:2011-10-05
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Structural Basis for the Broad Specificity to Host- Cell Ligands by the Pathogenic Fungus Candida Albicans.
Proc.Natl.Acad.Sci.USA, 108, 2011
2Y7M
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STRUCTURE OF N-TERMINAL DOMAIN OF CANDIDA ALBICANS ALS9-2 (PT DERIVATIVE)
Descriptor:AGGLUTININ-LIKE ALS9 PROTEIN
Authors:Salgado, P.S., Cota, E.
Deposit date:2011-01-31
Release date:2011-10-05
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural basis for the broad specificity to host-cell ligands by the pathogenic fungus Candida albicans.
Proc. Natl. Acad. Sci. U.S.A., 108, 2011
2Y7N
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STRUCTURE OF N-TERMINAL DOMAIN OF CANDIDA ALBICANS ALS9-2 - APO FORM
Descriptor:AGGLUTININ-LIKE ALS9 PROTEIN
Authors:Salgado, P.S., Cota, E.
Deposit date:2011-01-31
Release date:2011-10-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for the Broad Specificity to Host- Cell Ligands by the Pathogenic Fungus Candida Albicans.
Proc.Natl.Acad.Sci.USA, 108, 2011
2Y7O
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STRUCTURE OF N-TERMINAL DOMAIN OF CANDIDA ALBICANS ALS9-2 - G299W MUTANT
Descriptor:AGGLUTININ-LIKE ALS9 PROTEIN
Authors:Salgado, P.S., Burchell, L., Cota, E.
Deposit date:2011-01-31
Release date:2011-10-05
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis for the Broad Specificity to Host- Cell Ligands by the Pathogenic Fungus Candida Albicans.
Proc.Natl.Acad.Sci.USA, 108, 2011
2YLH
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STRUCTURE OF N-TERMINAL DOMAIN OF CANDIDA ALBICANS ALS9-2 G299W MUTANT
Descriptor:AGGLUTININ-LIKE PROTEIN
Authors:Salgado, P.S., Burchell, L., Cota, E.
Deposit date:2011-06-02
Release date:2011-10-05
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis for the Broad Specificity to Host- Cell Ligands by the Pathogenic Fungus Candida Albicans.
Proc.Natl.Acad.Sci.USA, 108, 2011
4AOM
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MTIP AND MYOA COMPLEX
Descriptor:MYOSIN A TAIL DOMAIN INTERACTING PROTEIN, MYOSIN-A
Authors:Salgado, P.S., Douse, C.H., Simpson, P.J., Thomas, J.C., Holder, A.A., Tate, E.W., Cota, E.
Deposit date:2012-03-29
Release date:2012-09-05
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.939 Å)
Cite:Regulation of the Plasmodium Motor Complex: Phosphorylation of Myosin a Tail Interacting Protein (Mtip) Loosens its Grip on Myoa
J.Biol.Chem., 287, 2012
4LE8
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STRUCTURE OF THE ALS3 ADHESIN FROM CANDIDA ALBICANS, RESIDUES 1-299 (MATURE SEQUENCE)
Descriptor:Agglutinin-like protein 3
Authors:Lin, J., Garnett, J.A., Cota, E.
Deposit date:2013-06-25
Release date:2014-09-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The peptide binding mechanism of Als3 mediates early attachment of Candida albicans to host cells
To be Published
4LEB
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STRUCTURE OF THE ALS3 ADHESIN FROM CANDIDA ALBICANS, RESIDUES 1-299 (MATURE SEQUENCE) IN COMPLEX WITH HEPTA-THREONINE
Descriptor:Agglutinin-like protein 3, hepta-threonine
Authors:Lin, J., Garnett, J.A., Cota, E.
Deposit date:2013-06-25
Release date:2014-05-14
Last modified:2014-07-16
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Peptide-binding Cavity Is Essential for Als3-mediated Adhesion of Candida albicans to Human Cells.
J.Biol.Chem., 289, 2014
4LEE
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STRUCTURE OF THE ALS3 ADHESIN FROM CANDIDA ALBICANS, RESIDUES 1-313 (MATURE SEQUENCE), TRIPLE MUTANT IN THE BINDING CAVITY: K59M, A116V, Y301F
Descriptor:Agglutinin-like protein 3
Authors:Lin, J., Garnett, J.A., Cota, E.
Deposit date:2013-06-25
Release date:2014-05-14
Last modified:2014-07-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Peptide-binding Cavity Is Essential for Als3-mediated Adhesion of Candida albicans to Human Cells.
J.Biol.Chem., 289, 2014
4MZJ
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CRYSTAL STRUCTURE OF MTIP FROM PLASMODIUM FALCIPARUM IN COMPLEX WITH PGLY[801,805], A STAPLED MYOA TAIL PEPTIDE
Descriptor:Myosin A tail domain interacting protein, Myosin-A
Authors:Douse, C.H., Garnett, J.A., Maas, S.J., Cota, E., Tate, E.W.
Deposit date:2013-09-30
Release date:2013-11-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.474 Å)
Cite:Crystal Structures of Stapled and Hydrogen Bond Surrogate Peptides Targeting a Fully Buried Protein-Helix Interaction.
Acs Chem.Biol., 8, 2014
4MZK
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CRYSTAL STRUCTURE OF MTIP FROM PLASMODIUM FALCIPARUM IN COMPLEX WITH PGLY[807,811], A STAPLED MYOA TAIL PEPTIDE
Descriptor:Myosin A tail domain interacting protein, pGly[807,811], a stapled myoA tail peptide
Authors:Douse, C.H., Garnett, J.A., Maas, S.J., Cota, E., Tate, E.W.
Deposit date:2013-09-30
Release date:2013-11-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal Structures of Stapled and Hydrogen Bond Surrogate Peptides Targeting a Fully Buried Protein-Helix Interaction.
Acs Chem.Biol., 8, 2014
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