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6NB8
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CRYSTAL STRUCTURE OF ANTI- SARS-COV HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT
Descriptor:S230 antigen-binding (Fab) fragment, heavy chain, light chain
Authors:Walls, A.J., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, J., Quispe, J., Cameroni, E., Gopal, R., Dai, M., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB7
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SARS-COV COMPLEX WITH HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT (STATE 2)
Descriptor:Spike glycoprotein, S230 heavy chain, S230 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB6
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SARS-COV COMPLEX WITH HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT (STATE 1)
Descriptor:Spike glycoprotein, S230 heavy chain, S230 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB5
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CRYSTAL STRUCTURE OF ANTI- MERS-COV HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT
Descriptor:LCA60 antigen-binding (Fab) fragment, heavy chain, light chain
Authors:Walls, A.J., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, J., Quispe, J., Cameroni, E., Gopal, R., Dai, M., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB4
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MERS-COV S COMPLEX WITH HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT (STATE 2)
Descriptor:Spike glycoprotein, LCA60 heavy chain, LCA60 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB3
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MERS-COV COMPLEX WITH HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT (STATE 1)
Descriptor:Spike glycoprotein, LCA60 light chain, LCA60 heavy chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6MJZ
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CRYO-EM STRUCTURE OF HUMAN PARAINFLUENZA VIRUS TYPE 3 (HPIV3) IN COMPLEX WITH ANTIBODY PIA174
Descriptor:Fusion glycoprotein F0, PIA174 Fab Heavy chain, PIA174 Fab Light chain
Authors:Acharya, P., Stewart-Jones, G., Carragher, B., Potter, C.S., Kwong, P.D.
Deposit date:2018-09-24
Release date:2018-11-14
Last modified:2018-12-12
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HKG
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STRUCTURE OF FISW84 FAB FRAGMENT
Descriptor:FISW84 Fab Fragment Heavy Chain, FISW84 Fab Fragment Light Chain, SULFATE ION
Authors:Benton, D.J., Rosenthal, P.B.
Deposit date:2018-09-06
Release date:2018-09-26
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Influenza hemagglutinin membrane anchor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HJR
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STRUCTURE OF FULL-LENGTH INFLUENZA HEMAGGLUTININ WITH TILTED TRANSMEMBRANE (A/DUCK/ALBERTA/35/76[H1N1])
Descriptor:Hemagglutinin, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Benton, D.J., Rosenthal, P.B.
Deposit date:2018-09-04
Release date:2018-09-26
Last modified:2018-10-10
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Influenza hemagglutinin membrane anchor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HJQ
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STRUCTURE OF FULL-LENGTH INFLUENZA HEMAGGLUTININ (A/DUCK/ALBERTA/35/76) IN COMPLEX WITH FISW84 FAB FRAGMENT
Descriptor:Hemagglutinin, Heavy chain of FISW84 Fab, Light chain of FISW84 Fab, ...
Authors:Benton, D.J., Rosenthal, P.B.
Deposit date:2018-09-04
Release date:2018-09-26
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Influenza hemagglutinin membrane anchor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HJP
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STRUCTURE OF INFLUENZA HEMAGGLUTININ ECTODOMAIN (A/DUCK/ALBERTA/35/76) IN COMPLEX WITH FISW84 FAB FRAGMENT
Descriptor:Hemagglutinin, Heavy chain of FISW84 Fab Fragment, Light chain of FISW84 Fab Fragment, ...
Authors:Benton, D.J., Rosenthal, P.B.
Deposit date:2018-09-04
Release date:2018-09-26
Last modified:2018-10-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Influenza hemagglutinin membrane anchor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HJN
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STRUCTURE OF INFLUENZA HEMAGGLUTININ ECTODOMAIN (A/DUCK/ALBERTA/35/76)
Descriptor:Hemagglutinin, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Benton, D.J., Rosenthal, P.B.
Deposit date:2018-09-04
Release date:2018-09-26
Last modified:2018-10-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Influenza hemagglutinin membrane anchor.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5Y0A
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CRYO-EM STRUCTURE OF ZIKA VIRUS COMPLEXED WITH FAB OF ZKA190 AT PH 8.0 AND 37 CELSIUS DEGREE
Descriptor:protein E, variable region of Fab ZKA190 heavy chain, variable region of Fab ZKA190 light chain
Authors:Wang, J.Q., Lok, S.M.
Deposit date:2017-07-15
Release date:2017-10-04
Method:ELECTRON MICROSCOPY (22 Å)
Cite:A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.
Cell, 171, 2017
5TDL
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CRYSTAL STRUCTURE OF PREFUSION-STABILIZED BOVINE RSV FUSION GLYCOPROTEIN (SINGLE-CHAIN DS2-V1 VARIANT: STRAIN 391-2 SC9 DS-CAV1 Q98C Q361C)
Descriptor:Bovine prefusion RSV F glycoprotein, N-ACETYL-D-GLUCOSAMINE
Authors:Chen, L., Zhang, B., Kwong, P.D.
Deposit date:2016-09-19
Release date:2017-08-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Protection of calves by a prefusion-stabilized bovine RSV F vaccine.
NPJ Vaccines, 2, 2017
5TDG
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CRYSTAL STRUCTURE OF PREFUSION-STABILIZED BOVINE RSV F (DS-CAV1 VARIANT: STRAIN ATUE51908)
Descriptor:Fusion glycoprotein F0,Fibritin, N-ACETYL-D-GLUCOSAMINE
Authors:Chen, L., Zhang, B., Kwong, P.D.
Deposit date:2016-09-19
Release date:2017-08-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Protection of calves by a prefusion-stabilized bovine RSV F vaccine.
NPJ Vaccines, 2, 2017
5OMZ
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SOLUTION STRUCTURE OF DOMAIN III (DIII)OF ZIKA VIRUS ENVELOPE PROTEIN
Descriptor:Envelope Protein
Authors:Zerbe, O., Bardelli, M.
Deposit date:2017-08-02
Release date:2017-10-04
Method:SOLUTION NMR
Cite:A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.
Cell, 171, 2017
5JW5
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STRUCTURE OF MEDI8852 FAB FRAGMENT
Descriptor:MEDI8852 Heavy chain, MEDI8852 Light chain, PHOSPHATE ION
Authors:Neu, U., Collins, P.J., Walker, P.A., Vorlaender, M.K., Ogrodowicz, R.W., Martin, S.R., Gamblin, S.J., Skehel, J.J.
Deposit date:2016-05-11
Release date:2016-08-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
5JW4
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STRUCTURE OF MEDI8852 FAB FRAGMENT IN COMPLEX WITH H5 HA
Descriptor:Hemagglutinin, MEDI8852 heavy chain, MEDI8852 light chain, ...
Authors:Neu, U., Collins, P.J., Walker, P.A., Vorlaender, M.K., Ogrodowicz, R.W., Martin, S.R., Gamblin, S.J., Skehel, J.J.
Deposit date:2016-05-11
Release date:2016-08-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
5JW3
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STRUCTURE OF MEDI8852 FAB FRAGMENT IN COMPLEX WITH H7 HA
Descriptor:Hemagglutinin, MEDI8852 heavy chain, MEDI8852 light chain, ...
Authors:Collins, P.J., Neu, U., Walker, P.A., Vorlaender, M.K., Ogrodowicz, R.W., Martin, S.R., Gamblin, S.J., Skehel, J.J.
Deposit date:2016-05-11
Release date:2016-08-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
5FHC
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CRYSTAL STRUCTURE OF PROTECTIVE HUMAN ANTIBODIES 100 AND 114 IN COMPLEX WITH EBOLA VIRUS FUSION GLYCOPROTEIN (GP)
Descriptor:Envelope glycoprotein, Envelope glycoprotein,Envelope glycoprotein, Antibody 100 Fab heavy chain, ...
Authors:Gilman, M.S.A., McLellan, J.S.
Deposit date:2015-12-21
Release date:2016-03-16
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (6.704 Å)
Cite:Structural and molecular basis for Ebola virus neutralization by protective human antibodies.
Science, 351, 2016
5FHB
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CRYSTAL STRUCTURE OF PROTECTIVE EBOLA VIRUS ANTIBODY 100
Descriptor:Antibody 100 Fab heavy chain, Antibody 100 Fab light chain, 1,2-ETHANEDIOL, ...
Authors:Gilman, M.S.A., McLellan, J.S.
Deposit date:2015-12-21
Release date:2016-03-16
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.973 Å)
Cite:Structural and molecular basis for Ebola virus neutralization by protective human antibodies.
Science, 351, 2016
5FHA
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CRYSTAL STRUCTURE OF PROTECTIVE EBOLA VIRUS ANTIBODY 114
Descriptor:Antibody 114 Fab heavy chain, Antibody 114 Fab light chain
Authors:Gilman, M.S.A., McLellan, J.S.
Deposit date:2015-12-21
Release date:2016-03-16
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.973 Å)
Cite:Structural and molecular basis for Ebola virus neutralization by protective human antibodies.
Science, 351, 2016
5A3I
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CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN FLD194 FAB AND TRANSMISSIBLE MUTANT H5 HAEMAGGLUTININ
Descriptor:HEMAGGLUTININ, ANTI-HAEMAGGLUTININ HA1 FAB HEAVY CHAIN, ANTI-HAEMAGGLUTININ HA1 FAB LIGHT CHAIN, ...
Authors:Xiong, X., Corti, D., Liu, J., Pinna, D., Foglierini, M., Calder, L.J., Martin, S.R., Lin, Y.P., Walker, P.A., Collins, P.J., Monne, I., Suguitan Jr, A.L., Santos, C., Temperton, N.J., Subbarao, K., Lanzavecchia, A., Gamblin, S.J., Skehel, J.J.
Deposit date:2015-06-01
Release date:2015-07-22
Last modified:2015-09-09
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structures of Complexes Formed by H5 Influenza Hemagglutinin with a Potent Broadly Neutralizing Human Monoclonal Antibody.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YFL
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CRYSTAL STRUCTURE OF VH1-46 GERMLINE-DERIVED CD4-BINDING SITE-DIRECTED ANTIBODY 1B2530 IN COMPLEX WITH HIV-1 CLADE A/E 93TH057 GP120
Descriptor:Envelope glycoprotein gp160,Envelope glycoprotein gp160,Envelope glycoprotein gp160, 1B2530 heavy chain, 1B2530 Light chain, ...
Authors:Acharya, P., Zhou, T., Moquin, S., Kwong, P.D.
Deposit date:2015-02-25
Release date:2015-06-03
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (3.387 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
4YDL
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY C38-VRC18.02 IN COMPLEX WITH HIV-1 CLADE AE STRAIN 93TH057GP120
Descriptor:Envelope glycoprotein gp160,Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY C38-VRC18.02, LIGHT CHAIN OF ANTIBODY C38-VRC18.02, ...
Authors:Zhou, T., Srivatsan, S., Kwong, P.D.
Deposit date:2015-02-22
Release date:2015-06-03
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
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