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3ZTN
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STRUCTURE OF INFLUENZA A NEUTRALIZING ANTIBODY SELECTED FROM CULTURES OF SINGLE HUMAN PLASMA CELLS IN COMPLEX WITH HUMAN H1 INFLUENZA HAEMAGGLUTININ.
Descriptor:HAEMAGGLUTININ, FI6V3 ANTIBODY LIGHT CHAIN, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Hubbard, P.A., Ritchie, A.J., Corti, D., Voss, J.E., Gamblin, S.J., Codoni, G., Macagno, A., Jarrossay, D., Pinna, D., Minola, A., Vanzetta, F., Silacci, C., Fernandez-Rodriguez, B.M., Agatic, G., Giacchetto-Sasselli, I., Vachieri, S.G., Sallusto, F., Collins, P.J., Haire, L.F., Temperton, N., Langedijk, J.P.M., Skehel, J.J., Lanzavecchia, A.
Deposit date:2011-07-12
Release date:2011-08-10
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:A Neutralizing Antibody Selected from Plasma Cells that Binds to Group 1 and Group 2 Influenza a Hemagglutinins.
Science, 333, 2011
6NB3
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MERS-COV COMPLEX WITH HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT (STATE 1)
Descriptor:Spike glycoprotein, LCA60 light chain, LCA60 heavy chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB4
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MERS-COV S COMPLEX WITH HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT (STATE 2)
Descriptor:Spike glycoprotein, LCA60 heavy chain, LCA60 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB6
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SARS-COV COMPLEX WITH HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT (STATE 1)
Descriptor:Spike glycoprotein, S230 heavy chain, S230 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB7
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SARS-COV COMPLEX WITH HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT (STATE 2)
Descriptor:Spike glycoprotein, S230 heavy chain, S230 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
2XRA
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CRYSTAL STRUCTURE OF THE HK20 FAB IN COMPLEX WITH A GP41 MIMETIC 5- HELIX
Descriptor:TRANSMEMBRANE PROTEIN GP41, HK20, HUMAN MONOCLONAL ANTIBODY HEAVY CHAIN, ...
Authors:Sabin, C., Corti, D., Buzon, V., Seaman, M.S., Lutje Hulsik, D., Hinz, A., Vanzetta, F., Agatic, G., Silacci, C., Langedijk, J.P.M., Mainetti, L., Scarlatti, G., Sallusto, F., Weiss, R., Lanzavecchia, A., Weissenhorn, W.
Deposit date:2010-09-13
Release date:2010-12-15
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and size-dependent neutralization properties of HK20, a human monoclonal antibody binding to the highly conserved heptad repeat 1 of gp41.
PLoS Pathog., 6, 2010
5A3I
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CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN FLD194 FAB AND TRANSMISSIBLE MUTANT H5 HAEMAGGLUTININ
Descriptor:HEMAGGLUTININ, ANTI-HAEMAGGLUTININ HA1 FAB HEAVY CHAIN, ANTI-HAEMAGGLUTININ HA1 FAB LIGHT CHAIN, ...
Authors:Xiong, X., Corti, D., Liu, J., Pinna, D., Foglierini, M., Calder, L.J., Martin, S.R., Lin, Y.P., Walker, P.A., Collins, P.J., Monne, I., Suguitan Jr, A.L., Santos, C., Temperton, N.J., Subbarao, K., Lanzavecchia, A., Gamblin, S.J., Skehel, J.J.
Deposit date:2015-06-01
Release date:2015-07-22
Last modified:2015-09-09
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structures of Complexes Formed by H5 Influenza Hemagglutinin with a Potent Broadly Neutralizing Human Monoclonal Antibody.
Proc.Natl.Acad.Sci.USA, 112, 2015
6NB5
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CRYSTAL STRUCTURE OF ANTI- MERS-COV HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT
Descriptor:LCA60 antigen-binding (Fab) fragment, heavy chain, light chain
Authors:Walls, A.J., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, J., Quispe, J., Cameroni, E., Gopal, R., Dai, M., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB8
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CRYSTAL STRUCTURE OF ANTI- SARS-COV HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT
Descriptor:S230 antigen-binding (Fab) fragment, heavy chain, light chain
Authors:Walls, A.J., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, J., Quispe, J., Cameroni, E., Gopal, R., Dai, M., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
3ZTJ
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STRUCTURE OF INFLUENZA A NEUTRALIZING ANTIBODY SELECTED FROM CULTURES OF SINGLE HUMAN PLASMA CELLS IN COMPLEX WITH HUMAN H3 INFLUENZA HAEMAGGLUTININ.
Descriptor:HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN, FI6V3 ANTIBODY HEAVY CHAIN, ...
Authors:Voss, J.E., Vachieri, S.G., Gamblin, S.J., Collins, P.J., Haire, L.F., Skehel, J.J.
Deposit date:2011-07-08
Release date:2011-08-10
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:A Neutralizing Antibody Selected from Plasma Cells that Binds to Group 1 and Group 2 Influenza a Hemagglutinins.
Science, 333, 2011
4RWY
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CRYSTAL STRUCTURE OF VH1-46 GERMLINE-DERIVED CD4-BINDING SITE-DIRECTED ANTIBODY 8ANC131 IN COMPLEX WITH HIV-1 CLADE B YU2 GP120
Descriptor:HIV-1 YU2 gp120, Antibody 8ANC131 Heavy chain, Antibody 8ANC131 Light chain, ...
Authors:Acharya, P., Luongo, T.S., Kwong, P.D.
Deposit date:2014-12-08
Release date:2015-07-01
Method:X-RAY DIFFRACTION (2.128 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell(Cambridge,Mass.), 161, 2015
4RX4
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CRYSTAL STRUCTURE OF VH1-46 GERMLINE-DERIVED CD4-BINDING SITE-DIRECTED ANTIBODY 8ANC134 IN COMPLEX WITH HIV-1 CLADE A Q842.D12 GP120
Descriptor:HIV-1 Clade A Q842.d12 gp120, 8ANC134 Heavy chain, 8ANC134 Light Chain, ...
Authors:Zhou, T., Acharya, P., Moquin, S., Kwong, P.D.
Deposit date:2014-12-08
Release date:2015-07-01
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell(Cambridge,Mass.), 161, 2015
4YDI
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CRYSTAL STRUCTURE OF BROAD AND POTENTLY NEUTRALIZING VRC01-CLASS ANTIBODY Z258-VRC27.01, ISOLATED FROM HUMAN DONOR Z258, IN COMPLEX WITH HIV-1 GP120 FROM CLADE A STRAIN Q23.17
Descriptor:Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY Z258-VRC27.01, LIGHT CHAIN OF ANTIBODY Z258-VRC27.01, ...
Authors:Zhou, T., Srivatsan, S., Kwong, P.D.
Deposit date:2015-02-22
Release date:2015-06-03
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (3.452 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
4YDJ
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY 44-VRC13.01 IN COMPLEX WITH HIV-1 CLADE AE STRAIN 93TH057 GP120
Descriptor:Envelope glycoprotein gp160,Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY 44-VRC13.01, LIGHT CHAIN OF ANTIBODY 44-VRC13.01, ...
Authors:Zhou, T., Moquin, S., Kwong, P.D.
Deposit date:2015-02-22
Release date:2015-06-03
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2.308 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
4YDK
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY C38-VRC16.01 IN COMPLEX WITH HIV-1 CLADE AE STRAIN 93TH057 GP120
Descriptor:Envelope glycoprotein gp160,Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY C38-VRC16.01, LIGHT CHAIN OF ANTIBODY C38-VRC16.01, ...
Authors:Zhou, T., Moquin, S., Zheng, A., Kwong, P.D.
Deposit date:2015-02-22
Release date:2015-06-03
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (2.051 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
4YDL
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CRYSTAL STRUCTURE OF BROADLY AND POTENTLY NEUTRALIZING ANTIBODY C38-VRC18.02 IN COMPLEX WITH HIV-1 CLADE AE STRAIN 93TH057GP120
Descriptor:Envelope glycoprotein gp160,Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY C38-VRC18.02, LIGHT CHAIN OF ANTIBODY C38-VRC18.02, ...
Authors:Zhou, T., Srivatsan, S., Kwong, P.D.
Deposit date:2015-02-22
Release date:2015-06-03
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
4YFL
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CRYSTAL STRUCTURE OF VH1-46 GERMLINE-DERIVED CD4-BINDING SITE-DIRECTED ANTIBODY 1B2530 IN COMPLEX WITH HIV-1 CLADE A/E 93TH057 GP120
Descriptor:Envelope glycoprotein gp160,Envelope glycoprotein gp160,Envelope glycoprotein gp160, 1B2530 heavy chain, 1B2530 Light chain, ...
Authors:Acharya, P., Zhou, T., Moquin, S., Kwong, P.D.
Deposit date:2015-02-25
Release date:2015-06-03
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (3.387 Å)
Cite:Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
5JW3
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STRUCTURE OF MEDI8852 FAB FRAGMENT IN COMPLEX WITH H7 HA
Descriptor:Hemagglutinin, MEDI8852 heavy chain, MEDI8852 light chain, ...
Authors:Collins, P.J., Neu, U., Walker, P.A., Vorlaender, M.K., Ogrodowicz, R.W., Martin, S.R., Gamblin, S.J., Skehel, J.J.
Deposit date:2016-05-11
Release date:2016-08-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
5JW4
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STRUCTURE OF MEDI8852 FAB FRAGMENT IN COMPLEX WITH H5 HA
Descriptor:Hemagglutinin, MEDI8852 heavy chain, MEDI8852 light chain, ...
Authors:Neu, U., Collins, P.J., Walker, P.A., Vorlaender, M.K., Ogrodowicz, R.W., Martin, S.R., Gamblin, S.J., Skehel, J.J.
Deposit date:2016-05-11
Release date:2016-08-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
5JW5
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STRUCTURE OF MEDI8852 FAB FRAGMENT
Descriptor:MEDI8852 Heavy chain, MEDI8852 Light chain, PHOSPHATE ION
Authors:Neu, U., Collins, P.J., Walker, P.A., Vorlaender, M.K., Ogrodowicz, R.W., Martin, S.R., Gamblin, S.J., Skehel, J.J.
Deposit date:2016-05-11
Release date:2016-08-03
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
5FHA
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CRYSTAL STRUCTURE OF PROTECTIVE EBOLA VIRUS ANTIBODY 114
Descriptor:Antibody 114 Fab heavy chain, Antibody 114 Fab light chain
Authors:Gilman, M.S.A., McLellan, J.S.
Deposit date:2015-12-21
Release date:2016-03-16
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.973 Å)
Cite:Structural and molecular basis for Ebola virus neutralization by protective human antibodies.
Science, 351, 2016
5FHB
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CRYSTAL STRUCTURE OF PROTECTIVE EBOLA VIRUS ANTIBODY 100
Descriptor:Antibody 100 Fab heavy chain, Antibody 100 Fab light chain, 1,2-ETHANEDIOL, ...
Authors:Gilman, M.S.A., McLellan, J.S.
Deposit date:2015-12-21
Release date:2016-03-16
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.973 Å)
Cite:Structural and molecular basis for Ebola virus neutralization by protective human antibodies.
Science, 351, 2016
5FHC
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CRYSTAL STRUCTURE OF PROTECTIVE HUMAN ANTIBODIES 100 AND 114 IN COMPLEX WITH EBOLA VIRUS FUSION GLYCOPROTEIN (GP)
Descriptor:Envelope glycoprotein, Envelope glycoprotein,Envelope glycoprotein, Antibody 100 Fab heavy chain, ...
Authors:Gilman, M.S.A., McLellan, J.S.
Deposit date:2015-12-21
Release date:2016-03-16
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (6.704 Å)
Cite:Structural and molecular basis for Ebola virus neutralization by protective human antibodies.
Science, 351, 2016
5OMZ
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SOLUTION STRUCTURE OF DOMAIN III (DIII)OF ZIKA VIRUS ENVELOPE PROTEIN
Descriptor:Envelope Protein
Authors:Zerbe, O., Bardelli, M.
Deposit date:2017-08-02
Release date:2017-10-04
Method:SOLUTION NMR
Cite:A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.
Cell, 171, 2017
5TDG
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CRYSTAL STRUCTURE OF PREFUSION-STABILIZED BOVINE RSV F (DS-CAV1 VARIANT: STRAIN ATUE51908)
Descriptor:Fusion glycoprotein F0,Fibritin, N-ACETYL-D-GLUCOSAMINE
Authors:Chen, L., Zhang, B., Kwong, P.D.
Deposit date:2016-09-19
Release date:2017-08-16
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Protection of calves by a prefusion-stabilized bovine RSV F vaccine.
NPJ Vaccines, 2, 2017
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