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2M8D
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BU of 2m8d by Molmil
Structure of SRSF1 RRM2 in complex with the RNA 5'-UGAAGGAC-3'
Descriptor: RNA (5'-R(*UP*GP*AP*AP*GP*GP*AP*C)-3'), Serine/arginine-rich splicing factor 1
Authors:Clery, A, Sinha, R, Anczukow, O, Corrionero, A, Moursy, A, Daubner, G, Valcarcel, J, Krainer, A.R, Allain, F.H.T.
Deposit date:2013-05-17
Release date:2013-07-10
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
4A7C
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BU of 4a7c by Molmil
Crystal structure of PIM1 kinase with ETP46546
Descriptor: ACETATE ION, IMIDAZOLE, N-(piperidin-4-ylmethyl)-3-[3-(trifluoromethyloxy)phenyl]-[1,2,3]triazolo[4,5-b]pyridin-5-amine, ...
Authors:Mazzorana, M, Montoya, G.
Deposit date:2011-11-12
Release date:2012-02-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Hit to Lead Evaluation of 1,2,3-Triazolo[4,5-B]Pyridines as Pim Kinase Inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012

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