7OFH
 
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8B3Q
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8B3P
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8B3O
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2PLX
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2QIH
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1U5A
 | | Plasmodium falciparum lactate dehydrogenase complexed with 3,5-dihydroxy-2-naphthoic acid | | Descriptor: | 3,7-DIHYDROXY-2-NAPHTHOIC ACID, L-lactate dehydrogenase | | Authors: | Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L. | | Deposit date: | 2004-07-27 | | Release date: | 2005-06-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
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1U4S
 | | Plasmodium falciparum lactate dehydrogenase complexed with 2,6-naphthalenedisulphonic acid | | Descriptor: | L-lactate dehydrogenase, NAPHTHALENE-2,6-DISULFONIC ACID | | Authors: | Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L. | | Deposit date: | 2004-07-26 | | Release date: | 2005-06-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
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1U4O
 | | Plasmodium falciparum lactate dehydrogenase complexed with 2,6-naphthalenedicarboxylic acid | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2,6-DICARBOXYNAPHTHALENE, L-lactate dehydrogenase | | Authors: | Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L. | | Deposit date: | 2004-07-26 | | Release date: | 2005-06-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
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1U5C
 | | Plasmodium falciparum lactate dehydrogenase complexed with 3,7-dihydroxynaphthalene-2-carboxylic acid and NAD+ | | Descriptor: | 3,7-DIHYDROXY-2-NAPHTHOIC ACID, L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Conners, R, Cameron, A, Read, J, Schambach, F, Sessions, R.B, Brady, R.L. | | Deposit date: | 2004-07-27 | | Release date: | 2005-06-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142, 2005
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1XIV
 | | Plasmodium falciparum lactate dehydrogenase complexed with 2-({4-chloro-[hydroxy(methoxy)methyl]cyclohexyl}amino)ethane-1,1,2-triol | | Descriptor: | 2-({4-CHLORO-2-[HYDROXY(METHOXY)METHYL]CYCLOHEXYL}AMINO)ETHANE-1,1,2-TRIOL, GLYCEROL, L-lactate dehydrogenase | | Authors: | Conners, R, Cameron, A, Read, J.A, Schambach, F, Sessions, R.B, Brady, R.L. | | Deposit date: | 2004-09-22 | | Release date: | 2005-06-21 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Mapping the binding site for gossypol-like inhibitors of Plasmodium
falciparum lactate dehydrogenase
MOL.BIOCHEM.PARASITOL., 142, 2005
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2A5C
 | | Structure of Avidin in complex with the ligand 8-oxodeoxyadenosine | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8-OXODEOXYADENOSINE, Avidin | | Authors: | Conners, R, Hooley, E, Thomas, S, Brady, R.L. | | Deposit date: | 2005-06-30 | | Release date: | 2006-05-23 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Recognition of oxidatively modified bases within the biotin-binding site of avidin.
J.Mol.Biol., 357, 2006
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2A8G
 | | Structure of Avidin in complex with the ligand deoxyguanosine | | Descriptor: | 2'-DEOXY-GUANOSINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin | | Authors: | Conners, R, Hooley, E, Thomas, S, Brady, R.L. | | Deposit date: | 2005-07-08 | | Release date: | 2006-05-23 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Recognition of oxidatively modified bases within the biotin-binding site of avidin.
J.Mol.Biol., 357, 2006
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2A5B
 | | Avidin complexed with 8-oxodeoxyguanosine | | Descriptor: | 2'-DEOXY-8-OXOGUANOSINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin | | Authors: | Conners, R, Hooley, E, Thomas, S, Brady, R.L. | | Deposit date: | 2005-06-30 | | Release date: | 2006-05-23 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Recognition of oxidatively modified bases within the biotin-binding site of avidin.
J.Mol.Biol., 357, 2006
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2CMY
 | | Crystal complex between bovine trypsin and Veronica hederifolia trypsin inhibitor | | Descriptor: | CALCIUM ION, CATIONIC TRYPSIN, GLYCEROL, ... | | Authors: | Conners, R, Yardley, J.L, Konarev, A, Shewry, P, Brady, R.L. | | Deposit date: | 2006-05-16 | | Release date: | 2007-05-22 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | An Unusual Helix-Turn-Helix Protease Inhibitory Motif in a Novel Trypsin Inhibitor from Seeds of Veronica (Veronica Hederifolia L.).
J.Biol.Chem., 282, 2007
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6SUZ
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6SV2
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3NTN
 | | Crystal Structure of UspA1 head and neck domain from Moraxella catarrhalis | | Descriptor: | CHLORIDE ION, NICKEL (II) ION, SULFATE ION, ... | | Authors: | Conners, R, Zaccai, N, Agnew, C, Burton, N, Brady, R.L. | | Deposit date: | 2010-07-05 | | Release date: | 2011-07-06 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Correlation of in situ mechanosensitive responses of the Moraxella catarrhalis adhesin UspA1 with fibronectin and receptor CEACAM1 binding.
Proc.Natl.Acad.Sci.USA, 108, 2011
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2WWR
 | | Crystal Structure of Human Glyoxylate Reductase Hydroxypyruvate Reductase | | Descriptor: | GLYOXYLATE REDUCTASE/HYDROXYPYRUVATE REDUCTASE, MAGNESIUM ION | | Authors: | Booth, M.P.S, Conners, R, Rumsby, G, Brady, R.L. | | Deposit date: | 2009-10-26 | | Release date: | 2010-10-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.82 Å) | | Cite: | Structural Basis of Substrate Specificity in Human Glyoxylate Reductase/Hydroxypyruvate Reductase.
J.Mol.Biol., 360, 2006
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8QOX
 | | Two-component assembly of SlaA and SlaB S-layer proteins of Sulfolobus acidocaldarius | | Descriptor: | Conserved membrane protein, S-layer protein A | | Authors: | Gambelli, L, McLaren, M, Isupov, M, Conners, R, Daum, B. | | Deposit date: | 2023-09-29 | | Release date: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (11.2 Å) | | Cite: | Structure of the two-component S-layer of the archaeon Sulfolobus acidocaldarius.
Elife, 13, 2024
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8QP0
 | | A hexamer pore in the S-layer of Sulfolobus acidocaldarius formed by SlaA protein | | Descriptor: | S-layer protein A | | Authors: | Gambelli, L, McLaren, M, Isupov, M, Conners, R, Daum, B. | | Deposit date: | 2023-09-29 | | Release date: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (11.2 Å) | | Cite: | Structure of the two-component S-layer of the archaeon Sulfolobus acidocaldarius.
Elife, 13, 2024
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7QCA
 | | Spraguea lophii ribosome | | Descriptor: | 40S Ribosomal protein S19, 40S ribosomal protein S0, 40S ribosomal protein S10, ... | | Authors: | Gil Diez, P, McLaren, M, Isupov, M.N, Daum, B, Conners, R, Williams, B. | | Deposit date: | 2021-11-22 | | Release date: | 2022-11-30 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (2.79 Å) | | Cite: | CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state
Nat Microbiol, 2023
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3IT5
 | | Crystal Structure of the LasA Virulence Factor from Pseudomonas aeruginosa | | Descriptor: | Protease lasA, ZINC ION | | Authors: | Spencer, J, Murphy, L.M, Conners, R, Sessions, R.B, Gamblin, S.J. | | Deposit date: | 2009-08-27 | | Release date: | 2009-11-17 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases.
J.Mol.Biol., 396, 2010
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3IT7
 | | Crystal Structure of the LasA virulence factor from Pseudomonas aeruginosa | | Descriptor: | GLYCEROL, L(+)-TARTARIC ACID, Protease lasA, ... | | Authors: | Spencer, J, Murphy, L.M, Conners, R, Sessions, R.B, Gamblin, S.J. | | Deposit date: | 2009-08-27 | | Release date: | 2009-11-17 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases.
J.Mol.Biol., 396, 2010
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2GCG
 | | Ternary Crystal Structure of Human Glyoxylate Reductase/Hydroxypyruvate Reductase | | Descriptor: | (2R)-2,3-DIHYDROXYPROPANOIC ACID, Glyoxylate reductase/hydroxypyruvate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Booth, M.P.S, Conners, R, Rumsby, G, Brady, R.L. | | Deposit date: | 2006-03-14 | | Release date: | 2006-07-18 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis of substrate specificity in human glyoxylate reductase/hydroxypyruvate reductase
J.Mol.Biol., 360, 2006
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