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4YEB
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STRUCTURAL CHARACTERIZATION OF A SYNAPTIC ADHESION COMPLEX
Descriptor:Latrophilin-3, Fibronectin leucine rich transmembrane protein 3, CALCIUM ION, ...
Authors:Ranaivoson, F.M., Liu, Q., Martini, F., Bergami, F., von Daake, S., Li, S., Lee, D., Demeler, B., Hendrickson, W.A., Comoletti, D.
Deposit date:2015-02-23
Release date:2015-08-19
Last modified:2015-09-23
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development.
Structure, 23, 2015
5FTT
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OCTAMERIC COMPLEX OF LATROPHILIN 3 (LEC, OLF) , UNC5D (IG, IG2, TSP1) AND FLRT2 (LRR)
Descriptor:NETRIN RECEPTOR UNC5D, LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2, ADHESION G PROTEIN-COUPLED RECEPTOR L3, ...
Authors:Jackson, V.A., Mehmood, S., Chavent, M., Roversi, P., Carrasquero, M., del Toro, D., Seyit-Bremer, G., Ranaivoson, F.M., Comoletti, D., Sansom, M.S.P., Robinson, C.V., Klein, R., Seiradake, E.
Deposit date:2016-01-15
Release date:2016-05-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors
Nat.Commun., 7, 2016
5FTU
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TETRAMERIC COMPLEX OF LATROPHILIN 3, UNC5D AND FLRT2
Descriptor:NETRIN RECEPTOR UNC5D, LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2, ADHESION G PROTEIN-COUPLED RECEPTOR L3, ...
Authors:Jackson, V.A., Mehmood, S., Chavent, M., Roversi, P., Carrasquero, M., del Toro, D., Seyit-Bremer, G., Ranaivoson, F.M., Comoletti, D., Sansom, M.S.P., Robinson, C.V., Klein, R., Seiradake, E.
Deposit date:2016-01-15
Release date:2016-05-04
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (6.01 Å)
Cite:Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors
Nat.Commun., 7, 2016
4RMK
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CRYSTAL STRUCTURE OF THE OLFACTOMEDIN DOMAIN OF LATROPHILIN 3 IN P65 CRYSTAL FORM
Descriptor:Latrophilin-3, CALCIUM ION
Authors:Ranaivoson, F.M., Liu, Q., Martini, F., Bergami, F., Von daake, S., Li, S., Demeler, B., Hendrickson, W.A., Comoletti, D.
Deposit date:2014-10-21
Release date:2015-08-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.606 Å)
Cite:Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development.
Structure, 23, 2015
4RML
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CRYSTAL STRUCTURE OF THE OLFACTOMEDIN DOMAIN OF LATROPHILIN 3 IN C2221 CRYSTAL FORM
Descriptor:Latrophilin-3, MAGNESIUM ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Ranaivoson, F.M., Liu, Q., Martini, F., Bergami, F., Von daake, S., Li, S., Demeler, B., Hendrickson, W.A., Comoletti, D.
Deposit date:2014-10-21
Release date:2015-08-19
Last modified:2015-10-07
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development.
Structure, 23, 2015
2WQZ
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CRYSTAL STRUCTURE OF SYNAPTIC PROTEIN NEUROLIGIN-4 IN COMPLEX WITH NEUREXIN-BETA 1: ALTERNATIVE REFINEMENT
Descriptor:NEUROLIGIN 4, X-LINKED, NEUREXIN-1-BETA, ...
Authors:Fabrichny, I.P., Leone, P., Sulzenbacher, G., Comoletti, D., Miller, M.T., Taylor, P., Bourne, Y., Marchot, P.
Deposit date:2009-08-28
Release date:2009-09-08
Last modified:2016-08-24
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural Analysis of the Synaptic Protein Neuroligin and its Beta-Neurexin Complex: Determinants for Folding and Cell Adhesion.
Neuron, 56, 2007
2XB6
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REVISITED CRYSTAL STRUCTURE OF NEUREXIN1BETA-NEUROLIGIN4 COMPLEX
Descriptor:NEUROLIGIN-4, X-LINKED, NEUREXIN-1-BETA, ...
Authors:Leone, P., Comoletti, D., Ferracci, G., Conrod, S., Garcia, S.U., Taylor, P., Bourne, Y., Marchot, P.
Deposit date:2010-04-07
Release date:2010-06-23
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insights Into the Exquisite Selectivity of Neurexin-Neuroligin Synaptic Interactions
Embo J., 29, 2010
3BE8
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CRYSTAL STRUCTURE OF THE SYNAPTIC PROTEIN NEUROLIGIN 4
Descriptor:Neuroligin-4, X-linked, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Fabrichny, I.P., Leone, P., Sulzenbacher, G., Comoletti, D., Miller, M.T., Taylor, P., Bourne, Y., Marchot, P.
Deposit date:2007-11-16
Release date:2008-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Analysis of the Synaptic Protein Neuroligin and Its beta-Neurexin Complex: Determinants for Folding and Cell Adhesion
Neuron, 56, 2007
3POY
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CRYSTAL STRUCTURE OF THE ALPHA-NEUREXIN-1 ECTODOMAIN, LNS 2-6
Descriptor:Neurexin-1-alpha, BETA-D-GLUCOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Miller, M.T., Mileni, M., Comoletti, D., Stevens, R.C., Harel, M., Taylor, P.
Deposit date:2010-11-23
Release date:2011-06-08
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:The crystal structure of the alpha-neurexin-1 extracellular region reveals a hinge point for mediating synaptic adhesion and function.
Structure, 19, 2011
6DLD
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CRYSTAL STRUCTURE OF IGLON5/NEGR1 HETERODIMER
Descriptor:IgLON family member 5, Neuronal growth regulator 1, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Ranaivoson, F.M., Turk, L.S., Ozkan, E., Montelione, G.T., Comoletti, D.
Deposit date:2018-06-01
Release date:2019-04-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of a heterodimer of neuronal cell surface proteins
Structure, 2019
6DLE
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CRYSTAL STRUCTURE OF IGLON5 HOMODIMER
Descriptor:IgLON family member 5, N-ACETYL-D-GLUCOSAMINE
Authors:Ranaivoson, F.M., Turk, L.S., Ozkan, E., Montelione, G.T., Comoletti, D.
Deposit date:2018-06-01
Release date:2019-04-10
Method:X-RAY DIFFRACTION (3.994 Å)
Cite:Structure of a heterodimer of neuronal cell surface proteins
Structure, 2019
6DLF
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CRYSTAL STRUCTURE OF NTRI HOMODIMER
Descriptor:Neurotrimin, N-ACETYL-D-GLUCOSAMINE
Authors:Ranaivoson, F.M., Turk, L.S., Ozkan, E., Montelione, G.T., Comoletti, D.
Deposit date:2018-06-01
Release date:2019-04-10
Method:X-RAY DIFFRACTION (3.446 Å)
Cite:Structure of a heterodimer of neuronal cell surface proteins
Structure, 2019
6HKC
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SOLUTION STRUCTURE OF THE SUSHI 1 DOMAIN OF GABABR1A
Descriptor:Gamma-aminobutyric acid type B receptor subunit 1
Authors:Volkov, A.N., Buts, L., Van Molle, I.
Deposit date:2018-09-06
Release date:2019-01-23
Method:SOLUTION NMR
Cite:Secreted amyloid-beta precursor protein functions as a GABABR1a ligand to modulate synaptic transmission.
Science, 363, 2019