7RAF
 
 | | AncAR1-Rev - progesterone - Tif2 | | Descriptor: | Ancestral androgen receptor, GLYCEROL, PROGESTERONE, ... | | Authors: | Colucci, J.K. | | Deposit date: | 2021-07-01 | | Release date: | 2022-07-27 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.551 Å) | | Cite: | AncAR1-Rev - progesterone - Tif2
To Be Published
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4LTW
 | | Ancestral Ketosteroid Receptor-Progesterone-Mifepristone Complex | | Descriptor: | 11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE, Ancestral Steroid Receptor 2, GLYCEROL, ... | | Authors: | Ortlund, E.A, Colucci, J.K. | | Deposit date: | 2013-07-24 | | Release date: | 2013-12-25 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.045 Å) | | Cite: | X-ray crystal structure of the ancestral 3-ketosteroid receptor-progesterone-mifepristone complex shows mifepristone bound at the coactivator binding interface.
Plos One, 8, 2013
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4FN9
 | | X-ray Crystal structure of the Ancestral 3-keto steroid receptor - Progesterone complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, GLYCEROL, ... | | Authors: | Colucci, J.K, Ortlund, E.A, Thornton, J.W. | | Deposit date: | 2012-06-19 | | Release date: | 2012-12-26 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Evolution of minimal specificity and promiscuity in steroid hormone receptors.
PLoS Genet., 8, 2012
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4FNE
 | | X-ray Crystal structure of the Ancestral 3-keto steroid receptor - DOC complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, DESOXYCORTICOSTERONE, ... | | Authors: | Ortlund, E.A, Colucci, J.K, Thornton, J, Eick, G, Harms, M. | | Deposit date: | 2012-06-19 | | Release date: | 2012-12-12 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.78 Å) | | Cite: | Evolution of minimal specificity and promiscuity in steroid hormone receptors.
PLoS Genet, 8, 2012
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8F8M
 | | LRH-1 bound to small molecule Tet and fragment of coactivator Tif2 | | Descriptor: | (1~{R},3~{a}~{R},6~{a}~{R})-4-phenyl-3~{a}-(1-phenylethenyl)-5-[9-(1~{H}-1,2,3,4-tetrazol-5-yl)nonyl]-2,3,6,6~{a}-tetrahydro-1~{H}-pentalen-1-ol, Nuclear receptor coactivator 2, Nuclear receptor subfamily 5 group A member 2 | | Authors: | Cato, M.L, Ortlund, E.A. | | Deposit date: | 2022-11-22 | | Release date: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Isosteric improvements to liver receptor homolog-1 small molecule modulators
To Be Published
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5UFS
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