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2X9E
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BU of 2x9e by Molmil
HUMAN MPS1 IN COMPLEX WITH NMS-P715
Descriptor: DUAL SPECIFICITY PROTEIN KINASE TTK, N-(2,6-DIETHYLPHENYL)-1-METHYL-8-({4-[(1-METHYLPIPERIDIN-4-YL)CARBAMOYL]-2-(TRIFLUOROMETHOXY)PHENYL}AMINO)-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE
Authors:Colombo, R, Caldarelli, M, Mennecozzi, M, Giorgini, M.L, Sola, F, Cappella, P, Perrera, C, DePaolini, S.R, Rusconi, L, Cucchi, U, Avanzi, N, Bertrand, J.A, Bossi, R.T, Pesenti, E, Galvani, A, Isacchi, A, Colotta, F, Donati, D, Moll, J.
Deposit date:2010-03-17
Release date:2010-12-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Targeting the Mitotic Checkpoint for Cancer Therapy with Nms-P715, an Inhibitor of Mps1 Kinase.
Cancer Res., 70, 2010
2V7A
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BU of 2v7a by Molmil
Crystal structure of the T315I Abl mutant in complex with the inhibitor PHA-739358
Descriptor: MAGNESIUM ION, N-[(3E)-5-[(2R)-2-METHOXY-2-PHENYLACETYL]PYRROLO[3,4-C]PYRAZOL-3(5H)-YLIDENE]-4-(4-METHYLPIPERAZIN-1-YL)BENZAMIDE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1
Authors:Modugno, M, Casale, E, Soncini, C, Rosettani, P, Colombo, R, Lupi, R, Rusconi, L, Fancelli, D, Carpinelli, P, Cameron, A.D, Isacchi, A, Moll, J.
Deposit date:2007-07-27
Release date:2007-09-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the T315I Abl Mutant in Complex with the Aurora Kinases Inhibitor Pha-739358.
Cancer Res., 67, 2007
7ZT8
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BU of 7zt8 by Molmil
Structure of E8 TCR in complex in human MR1 bound to 3FBA
Descriptor: 1,2-ETHANEDIOL, 3-methylbenzoic acid, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ...
Authors:Karuppiah, V, Srikannathasan, V, Robinson, R.A.
Deposit date:2022-05-09
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
7ZT3
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BU of 7zt3 by Molmil
Structure of E8 TCR in complex in human MR1 K43A
Descriptor: Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, TCR alpha, ...
Authors:Karuppiah, V, Srikannathasan, V, Robinson, R.A.
Deposit date:2022-05-09
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
7ZT2
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BU of 7zt2 by Molmil
Structure of E8 TCR in complex with human MR1 bound to 5-OP-RU
Descriptor: 1,2-ETHANEDIOL, 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, ...
Authors:Karuppiah, V, Srikannathasan, V, Robinson, R.A.
Deposit date:2022-05-09
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
7ZT4
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BU of 7zt4 by Molmil
Structure of E8 TCR in complex with human MR1 bound to 6FP
Descriptor: 2-azanyl-6-methyl-3~{H}-pteridin-4-one, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ...
Authors:Karuppiah, V, Robinson, R.A.
Deposit date:2022-05-09
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
7ZT5
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BU of 7zt5 by Molmil
Structure of E8 TCR in complex in human MR1 bound to 3FSA
Descriptor: 3-methanoyl-2-oxidanyl-benzoic acid, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ...
Authors:Karuppiah, V, Robinson, R.A.
Deposit date:2022-05-09
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
7ZT9
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BU of 7zt9 by Molmil
Structure of E8 TCR in complex in human MR1 bound to 4FBA
Descriptor: 1,2-ETHANEDIOL, 4-METHYLBENZOIC ACID, Beta-2-microglobulin, ...
Authors:Karuppiah, V, Srikannathasan, V, Robinson, R.A.
Deposit date:2022-05-09
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023
7ZT7
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BU of 7zt7 by Molmil
Structure of E8 TCR in complex in human MR1 bound to 5FSA
Descriptor: 1,2-ETHANEDIOL, 2-hydroxy-5-methylbenzoic acid, Beta-2-microglobulin, ...
Authors:Karuppiah, V, Robinson, R.A.
Deposit date:2022-05-09
Release date:2023-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses.
J.Exp.Med., 220, 2023

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