Author results

5TGI
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STRUCTURE OF THE SNX5 PX DOMAIN IN COMPLEX WITH CHLAMYDIAL PROTEIN INCE IN SPACE GROUP P212121
Descriptor:Sorting nexin-5, IncE
Authors:Collins, B., Paul, B.
Deposit date:2016-09-28
Release date:2017-06-28
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structure of the SNX5 PX domain in complex with chlamydial protein IncE
To Be Published
5TGJ
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STRUCTURE OF THE SNX5 PX DOMAIN IN COMPLEX WITH CHLAMYDIAL PROTEIN INCE IN SPACE GROUP I2
Descriptor:Sorting nexin-5, IncE
Authors:Collins, B., Paul, B.
Deposit date:2016-09-28
Release date:2017-10-11
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the SNX5 PX domain in complex with chlamydial protein IncE
To Be Published
6E8R
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STRUCTURE OF THE SNX32 PX DOMAIN IN COMPLEX WITH CHLAMYDIAL PROTEIN INCE IN SPACE GROUP I121
Descriptor:Sorting nexin-32, IncE
Authors:Paul, B., Collins, B.
Deposit date:2018-07-31
Release date:2018-09-26
Method:X-RAY DIFFRACTION (2.268 Å)
Cite:Crystal structure of the SNX32 PX domain in complex with the Chlamydia trachomatis inclusion protein IncE
To be Published
3KEC
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CRYSTAL STRUCTURE OF HUMAN MMP-13 COMPLEXED WITH A PHENYL-2H-TETRAZOLE COMPOUND
Descriptor:Collagenase 3, ZINC ION, CALCIUM ION, ...
Authors:Shieh, H.-S., Pavlovsky, A.G., Collins, B., Schnute, M.E.
Deposit date:2009-10-25
Release date:2010-11-10
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis.
Bioorg.Med.Chem.Lett., 20, 2010
3KEJ
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CRYSTAL STRUCTURE OF HUMAN MMP-13 COMPLEXED WITH A (PYRIDIN-4-YL)-2H-TETRAZOLE COMPOUND
Descriptor:Collagenase 3, ZINC ION, CALCIUM ION, ...
Authors:Shieh, H.-S., Collins, B., Schnute, M.E.
Deposit date:2009-10-26
Release date:2010-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis.
Bioorg.Med.Chem.Lett., 20, 2010
3KEK
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CRYSTAL STRUCTURE OF HUMAN MMP-13 COMPLEXED WITH A (PYRIDIN-4-YL)-2H-TETRAZOLE COMPOUND
Descriptor:Collagenase 3, ZINC ION, CALCIUM ION, ...
Authors:Shieh, H.-S., Collins, B., Schnute, M.E.
Deposit date:2009-10-26
Release date:2010-11-10
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis.
Bioorg.Med.Chem.Lett., 20, 2009
3PSN
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CRYSTAL STRUCTURE OF MOUSE VPS29 COMPLEXED WITH MN2+
Descriptor:Vacuolar protein sorting-associated protein 29, MANGANESE (II) ION
Authors:Swarbrick, J., Shaw, D., Chhabra, S., Ghai, R., Valkov, E., Norwood, S., Collins, B.
Deposit date:2010-12-02
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Conformational dynamics and biomolecular interactions of VPS29 studied by NMR and X-ray crystallography
To be Published
3PSO
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CRYSTAL STRUCTURE OF MOUSE VPS29 COMPLEXED WITH ZN2+
Descriptor:Vacuolar protein sorting-associated protein 29, ZINC ION
Authors:Swarbrick, J., Shaw, D., Chhabra, S., Ghai, R., Valkov, E., Norwood, S., Collins, B.
Deposit date:2010-12-02
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Conformational dynamics and biomolecular interactions of VPS29 studied by NMR and X-ray crystallography
To be Published
5E7B
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STRUCTURE OF A NANOBODY (VHH) FROM CAMEL AGAINST PHAGE TUC2009 RBP (BPPL, ORF53)
Descriptor:nanobody nano-L06
Authors:Legrand, P., Collins, B., Blangy, S., Murphy, J., Spinelli, S., Gutierrez, C., Richet, N., Kellenberger, C., Desmyter, A., Mahony, J., van Sinderen, D., Cambillau, C.
Deposit date:2015-10-12
Release date:2015-12-30
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules.
Mbio, 7, 2016
5E7F
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COMPLEX BETWEEN LACTOCOCCAL PHAGE TUC2009 RBP HEAD DOMAIN AND A NANOBODY (L06)
Descriptor:nanobody L06, Major structural protein 1
Authors:Legrand, P., Collins, B., Blangy, S., Murphy, J., Spinelli, S., Gutierrez, C., Richet, N., Kellenberger, C., Desmyter, A., Mahony, J., van Sinderen, D., Cambillau, C.
Deposit date:2015-10-12
Release date:2015-12-30
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules.
Mbio, 7, 2016
5E7T
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STRUCTURE OF THE TRIPOD (BPPUCT-A-L) FROM THE BASEPLATE OF BACTERIOPHAGE TUC2009
Descriptor:Minor structural protein 4, Minor structural protein 5, Major structural protein 1, ...
Authors:Legrand, P., Collins, B., Blangy, S., Murphy, J., Spinelli, S., Gutierrez, C., Richet, N., Kellenberger, C., Desmyter, A., Mahony, J., van Sinderen, D., Cambillau, C.
Deposit date:2015-10-13
Release date:2015-12-30
Last modified:2016-05-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules.
Mbio, 7, 2016
6N5X
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CRYSTAL STRUCTURE OF THE SNX5 PX DOMAIN IN COMPLEX WITH THE CI-MPR (SPACE GROUP P212121 - FORM 1)
Descriptor:Sorting nexin-5,Cation-independent mannose-6-phosphate receptor, GLYCEROL, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500)
Authors:Collins, B., Paul, B., Weeratunga, S.
Deposit date:2018-11-22
Release date:2019-09-18
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.051 Å)
Cite:Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Nat.Cell Biol., 21, 2019
6N5Y
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CRYSTAL STRUCTURE OF THE SNX5 PX DOMAIN IN COMPLEX WITH THE CI-MPR (SPACE GROUP P212121 - FORM 1)
Descriptor:Sorting nexin-5,Cation-independent mannose-6-phosphate receptor
Authors:Collins, B., Paul, B., Weeratunga, S.
Deposit date:2018-11-22
Release date:2019-09-18
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Nat.Cell Biol., 21, 2019
6N5Z
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CRYSTAL STRUCTURE OF THE SNX5 PX DOMAIN IN COMPLEX WITH THE SEMA4C
Descriptor:Sorting nexin-5,Semaphorin-4C, CHLORIDE ION
Authors:Collins, B., Paul, B., Weeratunga, S.
Deposit date:2018-11-22
Release date:2019-09-18
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Molecular identification of a BAR domain-containing coat complex for endosomal recycling of transmembrane proteins.
Nat.Cell Biol., 21, 2019
5TGH
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STRUCTURE OF THE SNX5 PX DOMAIN IN COMPLEX WITH CHLAMYDIAL PROTEIN INCE IN SPACE GROUP P32
Descriptor:Sorting nexin-5, IncE
Authors:Collins, B., Paul, B.
Deposit date:2016-09-27
Release date:2017-05-03
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the hijacking of endosomal sorting nexin proteins byChlamydia trachomatis.
Elife, 6, 2017
3LH8
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CRYSTAL STRUCTURE OF MOUSE VPS26B IN SPACEGROUP P41 21 2
Descriptor:Vacuolar protein sorting-associated protein 26B
Authors:Collins, B., Shaw, D., Norwood, S.
Deposit date:2010-01-21
Release date:2010-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Assembly and solution structure of the core retromer protein complex.
Traffic, 12, 2011
3LH9
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CRYSTAL STRUCTURE OF MOUSE VPS26B(L197S/R199E) IN SPACEGROUP P41 21 2
Descriptor:Vacuolar protein sorting-associated protein 26B
Authors:Collins, B., Shaw, D., Norwood, S.
Deposit date:2010-01-21
Release date:2010-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Assembly and solution structure of the core retromer protein complex.
Traffic, 12, 2011
3LHA
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CRYSTAL STRUCTURE OF MOUSE VPS26B(R240S/G241A/E242S) IN SPACEGROUP P41 21 2
Descriptor:Vacuolar protein sorting-associated protein 26B
Authors:Collins, B., Shaw, D., Norwood, S.
Deposit date:2010-01-21
Release date:2010-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Assembly and solution structure of the core retromer protein complex.
Traffic, 12, 2011
4QDH
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF MOUSE TLR9
Descriptor:Variable lymphocyte receptor B, Toll-like receptor 9 chimera, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Collins, B.C., Wilson, I.A.
Deposit date:2014-05-13
Release date:2014-06-11
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Crystal structure of the C-terminal domain of mouse TLR9.
Proteins, 82, 2014
4K2Y
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CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH FRAGMENT INHIBITOR 6-CHLORO-1,3-DIHYDRO-2H-INDOL-2-ONE
Descriptor:Chymase, ZINC ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Collins, B.K., Padyana, A.K.
Deposit date:2013-04-09
Release date:2013-05-29
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies.
J.Med.Chem., 56, 2013
4K5Z
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CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH FRAGMENT INHIBITOR 6-CHLORO-2,3-DIHYDRO-1H-ISOINDOL-1-ONE
Descriptor:Chymase, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Collins, B.K., Padyana, A.K.
Deposit date:2013-04-15
Release date:2013-05-29
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies.
J.Med.Chem., 56, 2013
4K60
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CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH FRAGMENT 6-BROMO-1,3-DIHYDRO-2H-INDOL-2-ONE
Descriptor:Chymase, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
Authors:Collins, B.K., Padyana, A.K.
Deposit date:2013-04-15
Release date:2013-05-29
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies.
J.Med.Chem., 56, 2013
4K69
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CRYSTAL STRUCTURE OF HUMAN CHYMASE IN COMPLEX WITH FRAGMENT LINKED BENZIMIDAZOLONE INHIBITOR: (3S)-3-{3-[(6-BROMO-2-OXO-2,3-DIHYDRO-1H-INDOL-4-YL)METHYL]-2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOL-1-YL}HEXANOIC ACID
Descriptor:Chymase, ZINC ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Collins, B.K., Padyana, A.K.
Deposit date:2013-04-15
Release date:2013-05-29
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies.
J.Med.Chem., 56, 2013
4P2A
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STRUCTURE OF MOUSE VPS26A BOUND TO RAT SNX27 PDZ DOMAIN
Descriptor:Vacuolar protein sorting-associated protein 26A, Sorting nexin-27, MERCURY (II) ION
Authors:Clairfeuille, T., Gallon, M., Mas, C., Ghai, R., Teasdale, R., Cullen, P., Collins, B.
Deposit date:2014-03-03
Release date:2014-09-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.
Proc.Natl.Acad.Sci.USA, 111, 2014
4PQO
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STRUCTURE OF THE HUMAN SNX14 PX DOMAIN IN SPACE GROUP I41
Descriptor:Sorting nexin-14
Authors:Mas, C., Norwood, S., Bugarcic, A., Kinna, G., Leneva, N., Kovtun, O., Teasdale, R., Collins, B.
Deposit date:2014-03-03
Release date:2014-09-03
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural Basis for Different Phosphoinositide Specificities of the PX Domains of Sorting Nexins Regulating G-protein Signaling.
J.Biol.Chem., 289, 2014
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