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2C9Y
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STRUCTURE OF HUMAN ADENYLATE KINASE 2
Descriptor:ADENYLATE KINASE ISOENZYME 2, MITOCHONDRIAL, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, ...
Authors:Bunkoczi, G., Filippakopoulos, P., Debreczeni, J.E., Turnbull, A., Papagrigoriou, E., Savitsky, P., Colebrook, S., von Delft, F., Arrowsmith, C., Edwards, A., Sundstrom, M., Weigelt, J., Knapp, S.
Deposit date:2005-12-15
Release date:2006-01-04
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of Human Adenylate Kinase 2
To be Published
2JC6
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CRYSTAL STRUCTURE OF HUMAN CALMODULIN-DEPENDENT PROTEIN KINASE 1D
Descriptor:CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1D, N-(5-METHYL-1H-PYRAZOL-3-YL)-2-PHENYLQUINAZOLIN-4-AMINE
Authors:Debreczeni, J.E., Rellos, P., Fedorov, O., Niesen, F.H., Bhatia, C., Shrestha, L., Salah, E., Smee, C., Colebrook, S., Berridge, G., Gileadi, O., Bunkoczi, G., Ugochukwu, E., Pike, A.C.W., von Delft, F., Knapp, S., Sundstrom, M., Weigelt, J., Arrowsmith, C.H., Edwards, A.
Deposit date:2006-12-19
Release date:2007-02-13
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Human Calmodulin-Dependent Protein Kinase 1D
To be Published
2BP1
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STRUCTURE OF THE AFLATOXIN ALDEHYDE REDUCTASE IN COMPLEX WITH NADPH
Descriptor:AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CITRATE ANION
Authors:Debreczeni, J.E., Lukacik, P., Kavanagh, K., Dubinina, E., Bray, J., Colebrook, S., Haroniti, A., Edwards, A., Arrowsmith, C., Sundstrom, M., von Delft, F., Gileadi, O., Oppermann, U.
Deposit date:2005-04-17
Release date:2005-05-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the Aflatoxin Aldehyde Reductase in Complex with Nadph
To be Published
2C2H
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CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP
Descriptor:RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 3, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
Authors:Debreczeni, J.E., Yang, X., Zao, Y., Elkins, J., Gileadi, C., Burgess, N., Colebrook, S., Gileadi, O., Fedorov, O., Bunkoczi, G., von Delft, F., Doyle, D., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A.
Deposit date:2005-09-29
Release date:2005-10-13
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of the Human Rac3 in Complex with Gdp
To be Published
2CLS
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THE CRYSTAL STRUCTURE OF THE HUMAN RND1 GTPASE IN THE ACTIVE GTP BOUND STATE
Descriptor:RHO-RELATED GTP-BINDING PROTEIN RHO6, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Pike, A.C.W., Yang, X., Colebrook, S., Gileadi, O., Sobott, F., Bray, J., Wen Hwa, L., Marsden, B., Zhao, Y., Schoch, G., Elkins, J., Debreczeni, J.E., Turnbull, A.P., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D.
Deposit date:2006-04-28
Release date:2006-05-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:The Crystal Structure of the Human Rnd1 Gtpase in the Active GTP Bound State
To be Published
2F5Y
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN FROM HUMAN RGS-3
Descriptor:regulator of G-protein signalling 3 isoform 1, SULFATE ION
Authors:Ugochukwu, E., Berridge, G., Johansson, C., Smee, C., Savitsky, P., Burgess, N., Colebrook, S., Yang, X., Elkins, J., Doyle, D., Turnbull, A., Papagrigoriou, E., Debreczeni, J., Bunkoczi, G., Gorrec, F., von Delft, F., Arrowsmith, C., Sundstrom, M., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)
Deposit date:2005-11-28
Release date:2005-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Crystal Structure of the PDZ Domain from Human RGS-3
To be Published
2FE5
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THE CRYSTAL STRUCTURE OF THE SECOND PDZ DOMAIN OF HUMAN DLG3
Descriptor:Presynaptic protein SAP102, SULFATE ION, GLYCEROL
Authors:Ugochukwu, E., Phillips, C., Schoch, G., Berridge, G., Salah, E., Colebrook, S., Smee, C., Savitsky, P., Bray, J., Elkins, J., Doyle, D., Bunkoczi, G., Debreczeni, J., Turnbull, A., Gorrec, F., von Delft, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)
Deposit date:2005-12-15
Release date:2005-12-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:The Crystal Structure of the Second PDZ Domain of Human DLG3
To be Published
2G0N
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THE CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP AND CHLORIDE
Descriptor:Ras-related C3 botulinum toxin substrate 3, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Ugochukwu, E., Yang, X., Zao, Y., Elkins, J., Gileadi, C., Burgess, N., Colebrook, S., Gileadi, O., Fedorov, O., Bunkoczi, G., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2006-02-13
Release date:2006-05-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Crystal Structure of the Human RAC3 in complex with GDP and Chloride
To be Published
2IZZ
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CRYSTAL STRUCTURE OF HUMAN PYRROLINE-5-CARBOXYLATE REDUCTASE
Descriptor:PYRROLINE-5-CARBOXYLATE REDUCTASE 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 1,2-ETHANEDIOL
Authors:Pike, A.C.W., Guo, K., Kavanagh, K., Pilka, E.S., Berridge, G., Colebrook, S., Bray, J., Salah, E., Savitsky, P., Papagrigoriou, E., Turnbull, A.P., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Oppermann, U.
Deposit date:2006-07-31
Release date:2006-08-01
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of Human Pyrroline-5-Carboxylate Reductase
To be Published
2OZF
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THE CRYSTAL STRUCTURE OF THE 2ND PDZ DOMAIN OF THE HUMAN NHERF-1 (SLC9A3R1)
Descriptor:Ezrin-radixin-moesin-binding phosphoprotein 50
Authors:Phillips, C., Papagrigoriou, E., Gileadi, C., Fedorov, O., Elkins, J., Berridge, G., Turnbull, A.P., Gileadi, O., Schoch, G., Smee, C., Bray, J., Savitsky, P., Uppenberg, J., von Delft, F., Gorrec, F., Umeano, C., Salah, E., Colebrook, S., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2007-02-26
Release date:2007-03-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of the 2nd PDZ domain of the human NHERF-1 (SLC9A3R1)
To be Published
2C30
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CRYSTAL STRUCTURE OF THE HUMAN P21-ACTIVATED KINASE 6
Descriptor:SERINE/THREONINE-PROTEIN KINASE PAK 6, PHOSPHATE ION, CHLORIDE ION
Authors:Filippakopoulos, P., Berridge, G., Bray, J., Burgess, N., Colebrook, S., Das, S., Eswaran, J., Gileadi, O., Papagrigoriou, E., Savitsky, P., Smee, C., Turnbull, A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Knapp, S.
Deposit date:2005-10-02
Release date:2006-02-08
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structures of the P21-Activated Kinases Pak4, Pak5, and Pak6 Reveal Catalytic Domain Plasticity of Active Group II Paks.
Structure, 15, 2007
2FCF
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THE CRYSTAL STRUCTURE OF THE 7TH PDZ DOMAIN OF MPDZ (MUPP-1)
Descriptor:Multiple PDZ domain protein
Authors:Papagrigoriou, E., Berridge, G., Johansson, C., Colebrook, S., Salah, E., Burgess, N., Smee, C., Savitsky, P., Bray, J., Schoch, G., Phillips, C., Gileadi, C., Soundarajan, M., Yang, X., Elkins, J.M., Gorrec, F., Turnbull, A., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2005-12-12
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2FNE
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THE CRYSTAL STRUCTURE OF THE 13TH PDZ DOMAIN OF MPDZ
Descriptor:Multiple PDZ domain protein
Authors:Papagrigoriou, E., Berridge, G., Johansson, C., Colebrook, S., Salah, E., Burgess, N., Smee, C., Savitsky, P., Bray, J., Schoch, G., Phillips, C., Gileadi, C., Soundarajan, M., Yang, X., Elkins, J.M., Gorrec, F., Turnbull, A., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2006-01-11
Release date:2006-01-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2GZV
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THE CYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMAN PICK1
Descriptor:PRKCA-binding protein
Authors:Debreczeni, J.E., Elkins, J.M., Yang, X., Berridge, G., Bray, J., Colebrook, S., Smee, C., Savitsky, P., Gileadi, O., Turnbull, A., von Delft, F., Doyle, D.A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)
Deposit date:2006-05-12
Release date:2006-07-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2HE4
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THE CRYSTAL STRUCTURE OF THE SECOND PDZ DOMAIN OF HUMAN NHERF-2 (SLC9A3R2) INTERACTING WITH A MODE 1 PDZ BINDING MOTIF
Descriptor:Na(+)/H(+) exchange regulatory cofactor NHE-RF2, 1,2-ETHANEDIOL
Authors:Papagrigoriou, E., Elkins, J.M., Berridge, G., Gileady, O., Colebrook, S., Gileadi, C., Salah, E., Savitsky, P., Pantic, N., Gorrec, F., Bunkoczi, G., Weigelt, J., Arrowsmith, C., Sundstrom, M., Edwards, A., Doyle, D.A., Structural Genomics Consortium (SGC)
Deposit date:2006-06-21
Release date:2006-07-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2IC5
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CRYSTAL STRUCTURE OF HUMAN RAC3 GROWN IN THE PRESENCE OF GPP(NH)P.
Descriptor:Ras-related C3 botulinum toxin substrate 3, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Ugochukwu, E., Yang, X., Zao, Y., Elkins, J., Gileadi, C., Burgess, N., Colebrook, S., Gileadi, O., Fedorov, O., Bunkoczi, G., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Doyle, D., Structural Genomics Consortium (SGC)
Deposit date:2006-09-12
Release date:2006-10-10
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of human RAC3 grown in the presence of Gpp(NH)p.
To be Published