Author results

6OWM
  • Download 6owm
  • View 6owm
Molmil generated image of 6owm
HORSE LIVER F93W ALCOHOL DEHYDROGENASE COMPLEXED WITH NAD AND PENTAFLUOROBENZYL ALCOHOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V.
Deposit date:2019-05-10
Release date:2019-05-22
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Substitutions of amino acid residues in the substrate binding site of horse liver alcohol dehydrogenase have small effects on structure but significantly affect catalysis of hydrogen transfer.
To Be Published
6OWP
  • Download 6owp
  • View 6owp
Molmil generated image of 6owp
HORSE LIVER F93W ALCOHOL DEHYDROGENASE COMPLEXED WITH NAD AND TRIFLUOROETHANOL
Descriptor:Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ...
Authors:Plapp, B.V.
Deposit date:2019-05-10
Release date:2019-05-22
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Substitutions of amino acid residues in the substrate binding site of horse liver alcohol dehydrogenase have small effects on structure but significantly affect catalysis of hydrogen transfer.
To Be Published
1A71
  • Download 1a71
  • View 1a71
Molmil generated image of 1a71
TERNARY COMPLEX OF AN ACTIVE SITE DOUBLE MUTANT OF HORSE LIVER ALCOHOL DEHYDROGENASE, PHE93=>TRP, VAL203=>ALA WITH NAD AND TRIFLUOROETHANOL
Descriptor:LIVER ALCOHOL DEHYDROGENASE, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Colby, T.D., Bahnson, B.J., Chin, J.K., Klinman, J.P., Goldstein, B.M.
Deposit date:1998-03-19
Release date:1998-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes.
Biochemistry, 37, 1998
1AXE
  • Download 1axe
  • View 1axe
Molmil generated image of 1axe
CRYSTAL STRUCTURE OF THE ACTIVE-SITE MUTANT PHE93->TRP OF HORSE LIVER ALCOHOL DEHYDROGENASE IN COMPLEX WITH NAD AND INHIBITOR TRIFLUOROETHANOL
Descriptor:ALCOHOL DEHYDROGENASE, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Colby, T.D., Chin, J.K., Goldstein, B.M.
Deposit date:1997-10-15
Release date:1998-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A link between protein structure and enzyme catalyzed hydrogen tunneling.
Proc.Natl.Acad.Sci.USA, 94, 1997
1AXG
  • Download 1axg
  • View 1axg
Molmil generated image of 1axg
CRYSTAL STRUCTURE OF THE VAL203->ALA MUTANT OF LIVER ALCOHOL DEHYDROGENASE COMPLEXED WITH COFACTOR NAD AND INHIBITOR TRIFLUOROETHANOL SOLVED TO 2.5 ANGSTROM RESOLUTION
Descriptor:ALCOHOL DEHYDROGENASE, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Colby, T.D., Chin, J.K., Bahnson, B.J., Goldstein, B.M., Klinman, J.P.
Deposit date:1997-10-15
Release date:1998-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A link between protein structure and enzyme catalyzed hydrogen tunneling.
Proc.Natl.Acad.Sci.USA, 94, 1997
1A72
  • Download 1a72
  • View 1a72
Molmil generated image of 1a72
AN ACTIVE-SITE DOUBLE MUTANT (PHE93->TRP, VAL203->ALA) OF HORSE LIVER ALCOHOL DEHYDROGENASE IN COMPLEX WITH THE ISOSTERIC NAD ANALOG CPAD
Descriptor:HORSE LIVER ALCOHOL DEHYDROGENASE, ZINC ION, 5-BETA-D-RIBOFURANOSYLPICOLINAMIDE ADENINE-DINUCLEOTIDE
Authors:Colby, T.D., Bahnson, B.J., Chin, J.K., Klinman, J.P., Goldstein, B.M.
Deposit date:1998-03-19
Release date:1998-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes.
Biochemistry, 37, 1998
1B3O
  • Download 1b3o
  • View 1b3o
Molmil generated image of 1b3o
TERNARY COMPLEX OF HUMAN TYPE-II INOSINE MONOPHOSPHATE DEHYDROGENASE WITH 6-CL-IMP AND SELENAZOLE ADENINE DINUCLEOTIDE
Descriptor:PROTEIN (INOSINE MONOPHOSPHATE DEHYDROGENASE 2), 6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE, ...
Authors:Colby, T.D., Vanderveen, K., Strickler, M.D., Goldstein, B.M.
Deposit date:1998-12-14
Release date:1999-04-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design.
Proc.Natl.Acad.Sci.USA, 96, 1999