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1XSF
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BU of 1xsf by Molmil
Solution structure of a resuscitation promoting factor domain from Mycobacterium tuberculosis
Descriptor: Probable resuscitation-promoting factor rpfB
Authors:Cohen-Gonsaud, M, Barthe, P, Henderson, B, Ward, J, Roumestand, C, Keep, N.H.
Deposit date:2004-10-19
Release date:2005-02-15
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:The structure of a resuscitation-promoting factor domain from Mycobacterium tuberculosis shows homology to lysozymes
Nat.Struct.Mol.Biol., 12, 2005
1UZL
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BU of 1uzl by Molmil
MabA from Mycobacterium tuberculosis
Descriptor: 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE, CESIUM ION
Authors:Cohen-Gonsaud, M, Ducasse, S, Quemard, A, Labesse, G.
Deposit date:2004-03-14
Release date:2005-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Maba from Mycobacterium Tuberculosis, a Reductase Involved in Long-Chain Fatty Acid Biosynthesis.
J.Mol.Biol., 320, 2002
1UZN
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BU of 1uzn by Molmil
MabA from Mycobacterium tuberculosis
Descriptor: 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE, CESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Cohen-Gonsaud, M, Ducasse, S, Quemard, A, Labesse, G.
Deposit date:2004-03-14
Release date:2005-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Crystal Structure of Maba from Mycobacterium Tuberculosis, a Reductase Involved in Long-Chain Fatty Acid Biosynthesis.
J.Mol.Biol., 320, 2002
1UZM
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BU of 1uzm by Molmil
MabA from Mycobacterium tuberculosis
Descriptor: 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE, CESIUM ION
Authors:Cohen-Gonsaud, M, Ducasse, S, Quemard, A, Labesse, G.
Deposit date:2004-03-14
Release date:2005-03-23
Last modified:2020-03-25
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Crystal Structure of Maba from Mycobacterium Tuberculosis, a Reductase Involved in Long-Chain Fatty Acid Biosynthesis.
J.Mol.Biol., 320, 2002
7NHZ
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BU of 7nhz by Molmil
NMR structure of Rv1813c from Mycobacterium tuberculosis
Descriptor: Uncharacterized protein Rv1813c
Authors:Barthe, P, Cohen-Gonsaud, M.
Deposit date:2021-02-11
Release date:2021-03-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A Mycobacterium tuberculosis effector targets mitochondrion, controls energy metabolism and limits cytochrome c exit.
To Be Published
2KFS
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BU of 2kfs by Molmil
NMR structure of Rv2175c
Descriptor: Conserved hypothetical regulatory protein
Authors:Barthe, P, Cohen-Gonsaud, M, Roumestand, C, Molle, V.
Deposit date:2009-02-27
Release date:2009-05-19
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Mycobacterium tuberculosis Ser/Thr Kinase Substrate Rv2175c Is a DNA-binding Protein Regulated by Phosphorylation.
J.Biol.Chem., 284, 2009
4U77
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BU of 4u77 by Molmil
BTB domain from Drosophila CP190
Descriptor: Centrosome-associated zinc finger protein CP190, DIMETHYL SULFOXIDE, GLYCEROL
Authors:Allemand, F, Cohen-Gonsaud, M, Labesse, G, Nollmann, M.
Deposit date:2014-07-30
Release date:2014-08-13
Last modified:2014-10-15
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Chromatin Insulator Factors Involved in Long-Range DNA Interactions and Their Role in the Folding of the Drosophila Genome.
Plos Genet., 10, 2014
6QKQ
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BU of 6qkq by Molmil
NMR solution structure of LSR2-T112D binding domain.
Descriptor: Nucleoid-associated protein Lsr2
Authors:Barthe, P, Cohen-Gonsaud, M, Mukamolova, G.V.
Deposit date:2019-01-30
Release date:2019-07-17
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the transcriptional regulator Lsr2 at threonine 112.
Mol.Microbiol., 112, 2019
6QKP
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BU of 6qkp by Molmil
NMR solution structure of LSR2 binding domain.
Descriptor: Nucleoid-associated protein Lsr2
Authors:Barthe, P, Cohen-Gonsaud, M, Mukamolova, G.V.
Deposit date:2019-01-30
Release date:2019-07-17
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the transcriptional regulator Lsr2 at threonine 112.
Mol.Microbiol., 112, 2019
4OW1
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BU of 4ow1 by Molmil
Crystal Structure of Resuscitation Promoting Factor C
Descriptor: 1,2-ETHANEDIOL, Resuscitation-promoting factor RpfC
Authors:Chauviac, F.X, Quay, D.H.X, Cohen-Gonsaud, M, Keep, N.H.
Deposit date:2014-01-29
Release date:2014-06-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The RpfC (Rv1884) atomic structure shows high structural conservation within the resuscitation-promoting factor catalytic domain.
Acta Crystallogr.,Sect.F, 70, 2014
7OQH
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BU of 7oqh by Molmil
CryoEM structure of the transcription termination factor Rho from Mycobacterium tuberculosis
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Transcription termination factor Rho
Authors:Saridakis, E, Vishwakarma, R, Lai Kee Him, J, Martin, K, Simon, I, Cohen-Gonsaud, M, Coste, F, Bron, P, Margeat, E, Boudvillain, M.
Deposit date:2021-06-03
Release date:2022-02-09
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Cryo-EM structure of transcription termination factor Rho from Mycobacterium tuberculosis reveals bicyclomycin resistance mechanism.
Commun Biol, 5, 2022
2NC8
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BU of 2nc8 by Molmil
NMR structure of the Mycobacterium tuberculosis LppM (Rv2171) protein folded domain
Descriptor: Lipoprotein LppM
Authors:Barthe, P, Cohen-Gonsaud, M.
Deposit date:2016-03-22
Release date:2016-09-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Mycobacterium tuberculosis LppM Displays an Original Structure and Domain Composition Linked to a Dual Localization.
Structure, 24, 2016
7QA5
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BU of 7qa5 by Molmil
Solution structure of the C terminal domain of MgtC (PA4635) from Pseudomonas aeruginosa
Descriptor: Protein MgtC
Authors:Barthe, P, Cohen-Gonsaud, M.
Deposit date:2021-11-16
Release date:2022-05-04
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of the C terminal domain of MgtC (PA4635) from Pseudomonas aeruginosa
To Be Published
2NTN
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BU of 2ntn by Molmil
Crystal structure of MabA-C60V/G139A/S144L
Descriptor: 3-oxoacyl-[acyl-carrier-protein] reductase
Authors:Poncet-Montange, G, Ducasse-Cabanot, S, Quemard, A, Labesse, G, Cohen-Gonsaud, M.
Deposit date:2006-11-08
Release date:2006-11-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Lack of dynamics in the MabA active site kills the enzyme activity: practical consequences for drug-design studies
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
2KB3
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BU of 2kb3 by Molmil
NMR Structure of the phosphorylated form of OdhI, pOdhI.
Descriptor: Oxoglutarate dehydrogenase inhibitor
Authors:Barthe, P, Roumestand, C, Canova, M, Hurard, C, Molle, V, Cohen-Gonsaud, M.
Deposit date:2008-11-20
Release date:2009-05-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Dynamic and Structural Characterization of a Bacterial FHA Protein Reveals a New Autoinhibition Mechanism.
Structure, 17, 2009
2KB4
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BU of 2kb4 by Molmil
NMR structure of the unphosphorylated form of OdhI, OdhI.
Descriptor: Oxoglutarate dehydrogenase inhibitor
Authors:Barthe, P, Roumestand, C, Canova, M, Hurard, C, Molle, V, Cohen-Gonsaud, M.
Deposit date:2008-11-20
Release date:2009-05-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Dynamic and Structural Characterization of a Bacterial FHA Protein Reveals a New Autoinhibition Mechanism.
Structure, 17, 2009
2KUI
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BU of 2kui by Molmil
NMR structure of the PASTA domain of Mycobacterium tuberculosis of PknB
Descriptor: Serine/threonine-protein kinase pknB
Authors:Barthe, P, Mukamolova, G, Roumestand, C, Cohen-Gonsaud, M.
Deposit date:2010-02-17
Release date:2010-04-14
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:The structure of PknB extracellular PASTA domain from mycobacterium tuberculosis suggests a ligand-dependent kinase activation
Structure, 18, 2010
2KUE
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BU of 2kue by Molmil
NMR structure of the PASTA domain 2 and 3 of Mycobacterium tuberculosis of PknB
Descriptor: Serine/threonine-protein kinase pknB
Authors:Barthe, P, Mukamolova, G, Roumestand, C, Cohen-Gonsaud, M.
Deposit date:2010-02-17
Release date:2010-04-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The structure of PknB extracellular PASTA domain from mycobacterium tuberculosis suggests a ligand-dependent kinase activation
Structure, 18, 2010
2KUF
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BU of 2kuf by Molmil
NMR structure of the PASTA domain 3 and 4 of Mycobacterium tuberculosis of PknB
Descriptor: Serine/threonine-protein kinase pknB
Authors:Barthe, P, Mukamolova, G, Roumestand, C, Cohen-Gonsaud, M.
Deposit date:2010-02-17
Release date:2010-04-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The structure of PknB extracellular PASTA domain from mycobacterium tuberculosis suggests a ligand-dependent kinase activation
Structure, 18, 2010
2KUD
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BU of 2kud by Molmil
NMR structure of the PASTA domain 1 and 2 of Mycobacterium tuberculosis of PknB
Descriptor: Serine/threonine-protein kinase pknB
Authors:Barthe, P, Mukamolova, G, Roumestand, C, Cohen-Gonsaud, M.
Deposit date:2010-02-17
Release date:2010-04-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The structure of PknB extracellular PASTA domain from mycobacterium tuberculosis suggests a ligand-dependent kinase activation
Structure, 18, 2010
7P3V
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BU of 7p3v by Molmil
B-Raf V600E structure bound to a new inhibitor
Descriptor: Serine/threonine-protein kinase B-raf, ~{N}-[3-[5-(2-azanylpyrimidin-4-yl)-2-[(3~{S})-morpholin-3-yl]-1,3-thiazol-4-yl]-2-fluoranyl-phenyl]-2,5-bis(fluoranyl)benzenesulfonamide
Authors:Schneider, M, Gelin, M, Cohen-Gonsaud, M, Labesse, G.
Deposit date:2021-07-08
Release date:2021-11-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding.
J.Med.Chem., 65, 2022
2LC0
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BU of 2lc0 by Molmil
Rv0020c_Nter structure
Descriptor: Putative uncharacterized protein TB39.8
Authors:Barthe, P.P, Cohen-Gonsaud, M.M, Roumestand, C.
Deposit date:2011-04-11
Release date:2011-11-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Insight into the Mycobacterium tuberculosis Rv0020c Protein and Its Interaction with the PknB Kinase
Structure, 19, 2011
2LC1
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BU of 2lc1 by Molmil
Rv0020c_FHA Structure
Descriptor: Putative uncharacterized protein TB39.8
Authors:Barthe, P.P, Cohen-Gonsaud, M.M, Roumestand, C.C.
Deposit date:2011-04-11
Release date:2011-11-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Insight into the Mycobacterium tuberculosis Rv0020c Protein and Its Interaction with the PknB Kinase
Structure, 19, 2011
2LQJ
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BU of 2lqj by Molmil
Solution structure of the C-terminal domain of the MgtC protein from Mycobacterium tuberculosis
Descriptor: Mg2+ transport protein
Authors:Yang, M, Yang, Y, Labesse, G, Blanc-Potard, A.
Deposit date:2012-03-07
Release date:2012-03-21
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The C-Terminal Domain of the Virulence Factor MgtC Is a Divergent ACT Domain.
J.Bacteriol., 194, 2012
6QTL
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BU of 6qtl by Molmil
Caffeine recognizing nanobody
Descriptor: CAFFEINE, VHH
Authors:Lesne, J, Guichou, J.F, Labesse, G, Cohen-Gonsaud, M.
Deposit date:2019-02-25
Release date:2019-04-10
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for chemically-induced homodimerization of a single domain antibody
To Be Published

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