Author results

4E3D
  • Download 4e3d
  • View 4e3d
Molmil generated image of 4e3d
NUCLEOPHILE RECOGNITION AS AN ALTERNATIVE INHIBITION MODE FOR BENZOIC ACID BASED CARBONIC ANHYDRASE INHIBITORS
分子名称:Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ...
著者Cohen, S.M.
登録日2012-03-09
公開日2012-06-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors
Chem.Commun.(Camb.), 48, 2012
4E3F
  • Download 4e3f
  • View 4e3f
Molmil generated image of 4e3f
NUCLEOPHILE RECOGNITION AS AN ALTERNATIVE INHIBITION MODE FOR BENZOIC ACID BASED CARBONIC ANHYDRASE INHIBITORS
分子名称:Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ...
著者Cohen, S.M., Martin, D.P.
登録日2012-03-09
公開日2012-06-27
最終更新日2018-03-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors
Chem.Commun.(Camb.), 48, 2012
4E3G
  • Download 4e3g
  • View 4e3g
Molmil generated image of 4e3g
NUCLEOPHILE RECOGNITION AS AN ALTERNATIVE INHIBITION MODE FOR BENZOIC ACID BASED CARBONIC ANHYDRASE INHIBITORS
分子名称:Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ...
著者Cohen, S.M., Martin, D.P.
登録日2012-03-09
公開日2012-06-27
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors
Chem.Commun.(Camb.), 48, 2012
4E3H
  • Download 4e3h
  • View 4e3h
Molmil generated image of 4e3h
NUCLEOPHILE RECOGNITION AS AN ALTERNATIVE INHIBITION MODE FOR BENZOIC ACID BASED CARBONIC ANHYDRASE INHIBITORS
分子名称:Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ...
著者Cohen, S.M., Martin, D.P.
登録日2012-03-09
公開日2012-06-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors
Chem.Commun.(Camb.), 48, 2012
4E49
  • Download 4e49
  • View 4e49
Molmil generated image of 4e49
NUCLEOPHILE RECOGNITION AS AN ALTERNATIVE INHIBITION MODE FOR BENZOIC ACID BASED CARBONIC ANHYDRASE INHIBITORS
分子名称:Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ...
著者Cohen, S.M., Martin, D.P.
登録日2012-03-12
公開日2012-06-27
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors
Chem.Commun.(Camb.), 48, 2012
4E4A
  • Download 4e4a
  • View 4e4a
Molmil generated image of 4e4a
NUCLEOPHILE RECOGNITION AS AN ALTERNATIVE INHIBITION MODE FOR BENZOIC ACID BASED CARBONIC ANHYDRASE INHIBITORS
分子名称:Carbonic anhydrase 2, ZINC ION, 2-sulfanylbenzoic acid, ...
著者Cohen, S.M., Martin, D.P.
登録日2012-03-12
公開日2012-06-27
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors
Chem.Commun.(Camb.), 48, 2012
1LU5
  • Download 1lu5
  • View 1lu5
Molmil generated image of 1lu5
2.4 ANGSTROM CRYSTAL STRUCTURE OF THE ASYMMETRIC PLATINUM COMPLEX {PT(AMMINE)(CYCLOHEXYLAMINE)}2+ BOUND TO A DODECAMER DNA DUPLEX
分子名称:5'-D(*CP*CP*TP*CP*TP*GP*GP*TP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*AP*CP*CP*AP*GP*AP*GP*G)-3', CIS-(AMMINE)(CYCLOHEXYLAMINE)PLATINUM(II) COMPLEX
著者Silverman, A.P., Bu, W., Cohen, S.M., Lippard, S.J.
登録日2002-05-21
公開日2002-12-20
最終更新日2012-02-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献2.4-A Crystal Structure of the Asymmetric Platinum Complex {Pt(ammine)(cyclohexylamine)}2+ Bound to a Dodecamer DNA Duplex
J.Biol.Chem., 277, 2002
2J0A
  • Download 2j0a
  • View 2j0a
Molmil generated image of 2j0a
STRUCTURE OF THE CATALYTIC DOMAIN OF MOUSE MANIC FRINGE
分子名称:BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE MANIC FRINGE, SULFATE ION, POTASSIUM ION
著者Jinek, M., Chen, Y.-W., Clausen, H., Cohen, S.M., Conti, E.
登録日2006-08-01
公開日2006-09-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Insights Into the Notch-Modifying Glycosyltransferase Fringe
Nat.Struct.Mol.Biol., 13, 2006
2J0B
  • Download 2j0b
  • View 2j0b
Molmil generated image of 2j0b
STRUCTURE OF THE CATALYTIC DOMAIN OF MOUSE MANIC FRINGE IN COMPLEX WITH UDP AND MANGANESE
分子名称:BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE MANIC FRINGE, SULFATE ION, POTASSIUM ION, ...
著者Jinek, M., Chen, Y.-W., Clausen, H., Cohen, S.M., Conti, E.
登録日2006-08-01
公開日2006-09-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Insights Into the Notch-Modifying Glycosyltransferase Fringe
Nat.Struct.Mol.Biol., 13, 2006
3HRS
  • Download 3hrs
  • View 3hrs
Molmil generated image of 3hrs
CRYSTAL STRUCTURE OF THE MANGANESE-ACTIVATED REPRESSOR SCAR: APO FORM
分子名称:Metalloregulator ScaR, SULFATE ION
著者Stoll, K.E., Draper, W.E., Kliegman, J.I., Golynskiy, M.V., Brew-Appiah, R.A.T., Brown, H.K., Breyer, W.A., Jakubovics, N.S., Jenkinson, H.F., Brennan, R.B., Cohen, S.M., Glasfeld, A.
登録日2009-06-09
公開日2009-06-23
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Characterization and structure of the manganese-responsive transcriptional regulator ScaR.
Biochemistry, 48, 2009
3HRT
  • Download 3hrt
  • View 3hrt
Molmil generated image of 3hrt
CRYSTAL STRUCTURE OF SCAR WITH BOUND CD2+
分子名称:Metalloregulator ScaR, SULFATE ION, CADMIUM ION
著者Stoll, K.E., Draper, W.E., Kliegman, J.I., Golynskiy, M.V., Brew-Appiah, R.A.T., Brown, H.K., Breyer, W.A., Jakubovics, N.S., Jenkinson, H.F., Brennan, R.B., Cohen, S.M., Glasfeld, A.
登録日2009-06-09
公開日2009-06-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Characterization and structure of the manganese-responsive transcriptional regulator ScaR.
Biochemistry, 48, 2009
3HRU
  • Download 3hru
  • View 3hru
Molmil generated image of 3hru
CRYSTAL STRUCTURE OF SCAR WITH BOUND ZN2+
分子名称:Metalloregulator ScaR, ZINC ION, SULFATE ION
著者Stoll, K.E., Draper, W.E., Kliegman, J.I., Golynskiy, M.V., Brew-Appiah, R.A.T., Brown, H.K., Breyer, W.A., Jakubovics, N.S., Jenkinson, H.F., Brennan, R.B., Cohen, S.M., Glasfeld, A.
登録日2009-06-09
公開日2009-06-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Characterization and structure of the manganese-responsive transcriptional regulator ScaR.
Biochemistry, 48, 2009
4JS6
  • Download 4js6
  • View 4js6
Molmil generated image of 4js6
CRYSTAL STRUCTURE OF INHIBITOR-FREE HCAII H94D
分子名称:Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID
著者Martin, D.P., Hann, Z.S., Cohen, S.M.
登録日2013-03-22
公開日2013-06-19
最終更新日2013-11-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Metalloprotein-Inhibitor Binding: Human Carbonic Anhydrase II as a Model for Probing Metal-Ligand Interactions in a Metalloprotein Active Site.
Inorg.Chem., 52, 2013
4JSA
  • Download 4jsa
  • View 4jsa
Molmil generated image of 4jsa
BENZENESULFONAMIDE COMPLEXED WITH HCAII H94D
分子名称:Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ...
著者Martin, D.P., Hann, Z.S., Cohen, S.M.
登録日2013-03-22
公開日2013-06-19
最終更新日2013-11-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Metalloprotein-Inhibitor Binding: Human Carbonic Anhydrase II as a Model for Probing Metal-Ligand Interactions in a Metalloprotein Active Site.
Inorg.Chem., 52, 2013
4JSS
  • Download 4jss
  • View 4jss
Molmil generated image of 4jss
HUMAN CARBONIC ANHYDRASE II H94D BOUND TO A BIDENTATE INHIBITOR
分子名称:Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ...
著者Martin, D.P., Hann, Z.S., Cohen, S.M.
登録日2013-03-22
公開日2013-06-19
最終更新日2013-11-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Metalloprotein-Inhibitor Binding: Human Carbonic Anhydrase II as a Model for Probing Metal-Ligand Interactions in a Metalloprotein Active Site.
Inorg.Chem., 52, 2013
4JSW
  • Download 4jsw
  • View 4jsw
Molmil generated image of 4jsw
HUMAN CARBONIC ANHYDRASE II H94C
分子名称:Carbonic anhydrase 2, ZINC ION
著者Martin, D.P., Hann, Z.S., Cohen, S.M.
登録日2013-03-22
公開日2013-06-19
最終更新日2013-11-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Metalloprotein-Inhibitor Binding: Human Carbonic Anhydrase II as a Model for Probing Metal-Ligand Interactions in a Metalloprotein Active Site.
Inorg.Chem., 52, 2013
4JSZ
  • Download 4jsz
  • View 4jsz
Molmil generated image of 4jsz
BENZENESULFONAMIDE BOUND TO HCAII H94C
分子名称:Carbonic anhydrase 2, ZINC ION, benzenesulfonamide
著者Martin, D.P., Hann, Z.S., Cohen, S.M.
登録日2013-03-22
公開日2013-06-19
最終更新日2013-11-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Metalloprotein-Inhibitor Binding: Human Carbonic Anhydrase II as a Model for Probing Metal-Ligand Interactions in a Metalloprotein Active Site.
Inorg.Chem., 52, 2013
4MLT
  • Download 4mlt
  • View 4mlt
Molmil generated image of 4mlt
STRUCTURE OF A MONODENTATE 3-HYDROXY-4H-PYRAN-4-THIONE LIGAND BOUND TO HCAII
分子名称:Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ...
著者Martin, D.P., Cohen, S.M.
登録日2013-09-06
公開日2014-07-02
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献'Unconventional' coordination chemistry by metal chelating fragments in a metalloprotein active site.
J.Am.Chem.Soc., 136, 2014
4MLX
  • Download 4mlx
  • View 4mlx
Molmil generated image of 4mlx
STRUCTURE OF A BIDENTATE 3-HYDROXY-4H-PYRAN-4-THIONE LIGAND BOUND TO HCAII
分子名称:Carbonic anhydrase 2, ZINC ION, MERCURIBENZOIC ACID, ...
著者Martin, D.P., Cohen, S.M.
登録日2013-09-06
公開日2014-07-02
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献'Unconventional' coordination chemistry by metal chelating fragments in a metalloprotein active site.
J.Am.Chem.Soc., 136, 2014
4Q7P
  • Download 4q7p
  • View 4q7p
Molmil generated image of 4q7p
CRYSTAL STRUCTURE OF 1-HYDROXY-3-METHYLPYRIDINE-2(1H)-THIONE BOUND TO HCAII
分子名称:Carbonic anhydrase 2, ZINC ION, 1-hydroxy-3-methylpyridine-2(1H)-thione, ...
著者Martin, D.P., Cohen, S.M.
登録日2014-04-25
公開日2015-03-11
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Exploring the influence of the protein environment on metal-binding pharmacophores.
J.Med.Chem., 57, 2014
4Q7S
  • Download 4q7s
  • View 4q7s
Molmil generated image of 4q7s
CRYSTAL STRUCTURE OF 1-HYDROXY-4-METHYLPYRIDINE-2(1H)-THIONE BOUND TO HUMAN CARBONIC ANHYDRASE II
分子名称:Carbonic anhydrase 2, ZINC ION, 1-hydroxy-4-methylpyridine-2(1H)-thione, ...
著者Martin, D.P., Cohen, S.M.
登録日2014-04-25
公開日2015-03-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Exploring the influence of the protein environment on metal-binding pharmacophores.
J.Med.Chem., 57, 2014
4Q7V
  • Download 4q7v
  • View 4q7v
Molmil generated image of 4q7v
CRYSTAL STRUCTURE OF 1-HYDROXY-5-METHYLPYRIDINE-2(1H)-THIONE BOUND TO HUMAN CARBONIC ANHYDRASE II
分子名称:Carbonic anhydrase 2, ZINC ION, 1-hydroxy-5-methylpyridine-2(1H)-thione, ...
著者Martin, D.P., Cohen, S.M.
登録日2014-04-25
公開日2015-03-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Exploring the influence of the protein environment on metal-binding pharmacophores.
J.Med.Chem., 57, 2014
4Q7W
  • Download 4q7w
  • View 4q7w
Molmil generated image of 4q7w
CRYSTAL STRUCTURE OF 1-HYDROXY-6-METHYLPYRIDINE-2(1H)-THIONE BOUND TO HUMAN CARBONIC ANHYDRASE II
分子名称:Carbonic anhydrase 2, ZINC ION, 1-hydroxy-6-methylpyridine-2(1H)-thione, ...
著者Martin, D.P., Cohen, S.M.
登録日2014-04-25
公開日2015-03-11
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Exploring the influence of the protein environment on metal-binding pharmacophores.
J.Med.Chem., 57, 2014
4Q81
  • Download 4q81
  • View 4q81
Molmil generated image of 4q81
CRYSTAL STRUCTURE OF 1-HYDROXY-4,6-DIMETHYLPYRIDINE-2(1H)-THIONE BOUND TO HUMAN CARBONIC ANHYDRASE II
分子名称:Carbonic anhydrase 2, ZINC ION, DIMETHYL SULFOXIDE, ...
著者Martin, D.P., Cohen, S.M.
登録日2014-04-25
公開日2015-03-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Exploring the influence of the protein environment on metal-binding pharmacophores.
J.Med.Chem., 57, 2014
4Q83
  • Download 4q83
  • View 4q83
Molmil generated image of 4q83
CRYSTAL STRUCTURE OF 1-HYDROXY-3-(TRIFLUOROMETHYL)PYRIDINE-2(1H)-THIONE BOUND TO HUMAN CARBONIC ANHYDRASE II
分子名称:Carbonic anhydrase 2, ZINC ION, 1-hydroxy-3-(trifluoromethyl)pyridine-2(1H)-thione, ...
著者Martin, D.P., Cohen, S.M.
登録日2014-04-25
公開日2015-03-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Exploring the influence of the protein environment on metal-binding pharmacophores.
J.Med.Chem., 57, 2014
<12>