Author results

1ZUC
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PROGESTERONE RECEPTOR LIGAND BINDING DOMAIN IN COMPLEX WITH THE NONSTEROIDAL AGONIST TANAPROGET
分子名称:Progesterone receptor, 5-(4,4-DIMETHYL-2-THIOXO-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-6-YL)-1-METHYL-1H-PYRROLE-2-CARBONITRILE, SULFATE ION
著者Zhang, Z., Olland, A.M., Zhu, Y., Cohen, J., Berrodin, T., Chippari, S., Appavu, C., Li, S., Wilhem, J., Chopra, R., Fensome, A., Zhang, P., Wrobel, J., Unwalla, R.J., Lyttle, C.R., Winneker, R.C.
登録日2005-05-30
公開日2005-07-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular and pharmacological properties of a potent and selective novel nonsteroidal progesterone receptor agonist tanaproget
J.Biol.Chem., 280, 2005
1N94
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ARYL TETRAHYDROPYRIDINE INHBITORS OF FARNESYLTRANSFERASE: GLYCINE, PHENYLALANINE AND HISTIDINE DERIVATES
分子名称:Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID, ...
著者Gwaltney II, S.L., O'Connor, S.J., Nelson, L.T., Sullivan, G.M., Imade, H., Wang, W., Hasvold, L., Li, Q., Cohen, J., Gu, W.Z.
登録日2002-11-22
公開日2003-01-07
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives.
Bioorg.Med.Chem.Lett., 13, 2003
1N95
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ARYL TETRAHYDROPHYRIDINE INHBITORS OF FARNESYLTRANFERASE: GLYCINE, PHENYLALANINE AND HISTIDINE DERIVATIVES
分子名称:Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ZINC ION, ...
著者Gwaltney II, S.L., O'Conner, S.J., Nelson, L.T., Sullivan, G.M., Imade, H., Wang, W., Hasvold, L., Li, Q., Cohen, J., Gu, W.Z.
登録日2002-11-22
公開日2003-01-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives.
Bioorg.Med.Chem.Lett., 13, 2003
1N9A
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FARNESYLTRANSFERASE COMPLEX WITH TETRAHYDROPYRIDINE INHIBITORS
分子名称:Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ZINC ION, ...
著者Gwaltney II, S.L., O'Conner, S.J., Nelson, L.T., Sullivan, G.M., Imade, H., Wang, W., Hasvold, L., Li, Q., Cohen, J., Gu, W.Z.
登録日2002-11-22
公開日2003-01-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Aryl tetrahydropyridine inhibitors of farnesyltransferase: bioavailable analogues with improved cellular potency.
Bioorg.Med.Chem.Lett., 13, 2003
1NI1
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IMIDAZOLE AND CYANOPHENYL FARNESYL TRANSFERASE INHIBITORS
分子名称:Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ZINC ION, ...
著者Tong, Y., Lin, N.H., Wang, L., Hasvold, L., Wang, W., Leonard, N., Li, T., Li, Q., Cohen, J., Gu, W.Z., Zhang, H., Stoll, V., Bauch, J., Marsh, K., Rosenberg, S.H., Sham, H.L.
登録日2002-12-20
公開日2004-04-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability.
Bioorg.Med.Chem.Lett., 13, 2003
1NL4
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CRYSTAL STRUCTURE OF RAT FARNESYL TRANSFERASE IN COMPLEX WITH A POTENT BIPHENYL INHIBITOR
分子名称:Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ZINC ION, ...
著者Curtin, M.L., Florjancic, A.S., Cohen, J., Gu, W.-J., Frost, D.J., Muchmore, S.W., Sham, H.L.
登録日2003-01-06
公開日2003-02-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Novel and Selective Imidazole-containing Biphenyl Inhibitors of Protein Farnesyltransferase
BIOORG.MED.CHEM.LETT., 13, 2003
1X81
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FARNESYL TRANSFERASE STRUCTURE OF JANSEN COMPOUND
分子名称:Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, Protein farnesyltransferase beta subunit, ZINC ION, ...
著者Li, Q., Claiborne, A., Li, T., Hasvold, L., Stoll, V.S., Muchmore, S., Jakob, C.G., Gu, W., Cohen, J., Hutchins, C., Frost, D., Rosenberg, S.H., Sham, H.L.
登録日2004-08-16
公開日2004-12-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors.
Bioorg.Med.Chem.Lett., 14, 2004
3G46
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LIGAND MIGRATION AND CAVITIES WITHIN SCAPHARCA DIMERIC HEMOGLOBIN: WILD TYPE WITH CO BOUND TO HEME AND CHLOROFORM BOUND TO THE XE4 CAVITY
分子名称:Globin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ...
著者Knapp, J.E., Pahl, R., Cohen, J., Nichols, J.C., Schulten, K., Gibson, Q.H., Srajer, V., Royer Jr., W.E.
登録日2009-02-03
公開日2009-12-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (0.91 Å)
主引用文献Ligand migration and cavities within Scapharca Dimeric HbI: studies by time-resolved crystallo-graphy, Xe binding, and computational analysis.
Structure, 17, 2009
3G4Q
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LIGAND MIGRATION AND CAVITIES WITHIN SCAPHARCA DIMERIC HEMOGLOBIN: WILD TYPE WITH CO BOUND TO HEME AND CHLOROFORM BOUND TO THE XE4 CAVITY
分子名称:Globin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ...
著者Knapp, J.E., Pahl, R., Cohen, J., Nichols, J.C., Schulten, K., Gibson, Q.H., Srajer, V., Royer Jr., W.E.
登録日2009-02-04
公開日2009-12-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Ligand migration and cavities within Scapharca Dimeric HbI: studies by time-resolved crystallo-graphy, Xe binding, and computational analysis.
Structure, 17, 2009
3G4R
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LIGAND MIGRATION AND CAVITIES WITHIN SCAPHARCA DIMERIC HEMOGLOBIN: WILD TYPE WITH CO BOUND TO HEME AND DICHLOROETHANE BOUND TO THE XE4 CAVITY
分子名称:Globin-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ...
著者Knapp, J.E., Pahl, R., Cohen, J., Nichols, J.C., Schulten, K., Gibson, Q.H., Srajer, V., Royer Jr., W.E.
登録日2009-02-04
公開日2009-12-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Ligand migration and cavities within Scapharca Dimeric HbI: studies by time-resolved crystallo-graphy, Xe binding, and computational analysis.
Structure, 17, 2009
3G4U
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LIGAND MIGRATION AND CAVITIES WITHIN SCAPHARCA DIMERIC HEMOGLOBIN: WILD TYPE WITH CO BOUND TO HEME AND DICHLOROPROPANE BOUND TO THE XE4 CAVITY
分子名称:GLOBIN-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ...
著者Knapp, J.E., Pahl, R., Cohen, J., Nichols, J.C., Schulten, K., Gibson, Q.H., Srajer, V., Royer Jr., W.E.
登録日2009-02-04
公開日2009-12-01
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Ligand migration and cavities within Scapharca Dimeric HbI: studies by time-resolved crystallo-graphy, Xe binding, and computational analysis.
Structure, 17, 2009
3G4V
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LIGAND MIGRATION AND CAVITIES WITHIN SCAPHARCA DIMERIC HEMOGLOBIN: WILD TYPE WITH CO BOUND TO HEME AND CHLOROPENTANE BOUND TO THE XE4 CAVITY
分子名称:GLOBIN-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ...
著者Knapp, J.E., Pahl, R., Cohen, J., Nichols, J.C., Schulten, K., Gibson, Q.H., Srajer, V., Royer Jr., W.E.
登録日2009-02-04
公開日2009-12-01
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Ligand migration and cavities within Scapharca Dimeric HbI: studies by time-resolved crystallo-graphy, Xe binding, and computational analysis.
Structure, 17, 2009
3G4W
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LIGAND MIGRATION AND CAVITIES WITHIN SCAPHARCA DIMERIC HEMOGLOBIN: WILD TYPE WITH CO BOUND TO HEME AND CHLOROBENZENE BOUND TO THE XE4 CAVITY
分子名称:GLOBIN-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ...
著者Knapp, J.E., Pahl, R., Cohen, J., Nichols, J.C., Schulten, K., Gibson, Q.H., Srajer, V., Royer Jr., W.E.
登録日2009-02-04
公開日2009-12-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Ligand migration and cavities within Scapharca Dimeric HbI: studies by time-resolved crystallo-graphy, Xe binding, and computational analysis.
Structure, 17, 2009
3G4Y
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LIGAND MIGRATION AND CAVITIES WITHIN SCAPHARCA DIMERIC HEMOGLOBIN: WILD TYPE WITH CO BOUND TO HEME AND CHLOROMETHYL BENZENE BOUND TO THE XE4 CAVITY
分子名称:GLOBIN-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ...
著者Knapp, J.E., Pahl, R., Cohen, J., Nichols, J.C., Schulten, K., Gibson, Q.H., Srajer, V., Royer Jr., W.E.
登録日2009-02-04
公開日2009-12-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Ligand migration and cavities within Scapharca Dimeric HbI: studies by time-resolved crystallo-graphy, Xe binding, and computational analysis.
Structure, 17, 2009
3G52
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LIGAND MIGRATION AND CAVITIES WITHIN SCAPHARCA DIMERIC HEMOGLOBIN: WILD TYPE WITH CO BOUND TO HEME AND CHLOROETHYL BENZENE BOUND TO THE XE4 CAVITY
分子名称:GLOBIN-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ...
著者Knapp, J.E., Pahl, R., Cohen, J., Nichols, J.C., Schulten, K., Gibson, Q.H., Srajer, V., Royer Jr., W.E.
登録日2009-02-04
公開日2009-12-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Ligand migration and cavities within Scapharca Dimeric HbI: studies by time-resolved crystallo-graphy, Xe binding, and computational analysis.
Structure, 17, 2009
3G53
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LIGAND MIGRATION AND CAVITIES WITHIN SCAPHARCA DIMERIC HEMOGLOBIN: WILD TYPE WITH CO BOUND TO HEME AND CHLOROPROPYL BENZENE BOUND TO THE XE4 CAVITY
分子名称:GLOBIN-1, PROTOPORPHYRIN IX CONTAINING FE, CARBON MONOXIDE, ...
著者Knapp, J.E., Pahl, R., Cohen, J., Nichols, J.C., Schulten, K., Gibson, Q.H., Srajer, V., Royer Jr., W.E.
登録日2009-02-04
公開日2009-12-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Ligand migration and cavities within Scapharca Dimeric HbI: studies by time-resolved crystallo-graphy, Xe binding, and computational analysis.
Structure, 17, 2009
1QHD
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CRYSTAL STRUCTURE OF VP6, THE MAJOR CAPSID PROTEIN OF GROUP A ROTAVIRUS
分子名称:VIRAL CAPSID VP6, ZINC ION, CHLORIDE ION, ...
著者Mathieu, M., Petitpas, I., Rey, F.A.
登録日1999-04-29
公開日2001-04-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Atomic structure of the major capsid protein of rotavirus: implications for the architecture of the virion.
EMBO J., 20, 2001
2OOV
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CRYSTAL STRUCTURE OF HANSENULA POLYMORPHA AMINE OXIDASE TO 1.7 ANGSTROMS
分子名称:Peroxisomal copper amine oxidase, COPPER (II) ION, GLYCEROL, ...
著者Johnson, B.J., Wilmot, C.M.
登録日2007-01-26
公開日2007-04-10
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Exploring molecular oxygen pathways in Hansenula polymorpha copper-containing amine oxidase
J.Biol.Chem., 282, 2007
2OQE
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CRYSTAL STRUCTURE OF HANSENULA POLYMORPHA AMINE OXIDASE IN COMPLEX WITH XE TO 1.6 ANGSTROMS
分子名称:Peroxisomal copper amine oxidase, COPPER (II) ION, XENON, ...
著者Johnson, B.J., Wilmot, C.M.
登録日2007-01-31
公開日2007-04-10
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Exploring molecular oxygen pathways in Hansenula polymorpha copper-containing amine oxidase
J.Biol.Chem., 282, 2007