1XGK
 
 | | CRYSTAL STRUCTURE OF N12G AND A18G MUTANT NMRA | | Descriptor: | CHLORIDE ION, GLYCEROL, NITROGEN METABOLITE REPRESSION REGULATOR NMRA, ... | | Authors: | Lamb, H.K, Ren, J, Park, A, Johnson, C, Leslie, K, Cocklin, S, Thompson, P, Mee, C, Cooper, A, Stammers, D.K, Hawkins, A.R. | | Deposit date: | 2004-09-17 | | Release date: | 2004-12-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Modulation of the ligand binding properties of the transcription repressor NmrA by GATA-containing DNA and site-directed mutagenesis
Protein Sci., 13, 2004
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1K6X
 | | Crystal structure of Nmra, a negative transcriptional regulator in complex with NAD at 1.5 A resolution (Trigonal form) | | Descriptor: | CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, NmrA | | Authors: | Stammers, D.K, Ren, J, Leslie, K, Nichols, C.E, Lamb, H.K, Cocklin, S, Dodds, A, Hawkins, A.R. | | Deposit date: | 2001-10-17 | | Release date: | 2002-02-20 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases.
EMBO J., 20, 2002
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1K6J
 | | Crystal structure of Nmra, a negative transcriptional regulator (Monoclinic form) | | Descriptor: | CHLORIDE ION, NmrA | | Authors: | Stammers, D.K, Ren, J, Leslie, K, Nichols, C.E, Lamb, H.K, Cocklin, S, Dodds, A, Hawkins, A.R. | | Deposit date: | 2001-10-16 | | Release date: | 2002-02-20 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases.
EMBO J., 20, 2001
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1K6I
 | | Crystal structure of Nmra, a negative transcriptional regulator (Trigonal form) | | Descriptor: | CHLORIDE ION, NmrA | | Authors: | Stammers, D.K, Ren, J, Leslie, K, Nichols, C.E, Lamb, H.K, Cocklin, S, Dodds, A, Hawkins, A.R. | | Deposit date: | 2001-10-16 | | Release date: | 2001-12-05 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases.
EMBO J., 20, 2001
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8TQP
 | | HIV-CA Disulfide linked Hexamer bound to Quinazolin-4-one Scaffold inhibitor | | Descriptor: | 2-[4-(4-aminobenzene-1-sulfonyl)-2-oxopiperazin-1-yl]-N-{(1R)-2-(3,5-difluorophenyl)-1-[3-(4-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]ethyl}acetamide, Gag polyprotein | | Authors: | Goldstone, D.C, Barnett, M.J, Taka, J.R.H. | | Deposit date: | 2023-08-08 | | Release date: | 2023-12-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Discovery, Crystallographic Studies, and Mechanistic Investigations of Novel Phenylalanine Derivatives Bearing a Quinazolin-4-one Scaffold as Potent HIV Capsid Modulators.
J.Med.Chem., 66, 2023
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8TOV
 | | HIV-CA Disulfide linked Hexamer bound to Quinazolin-4-one Scaffold inhibitor | | Descriptor: | 2-[4-(4-aminobenzene-1-sulfonyl)-2-oxopiperazin-1-yl]-N-[(1R)-2-(3,5-difluorophenyl)-1-{3-[4-(morpholine-4-sulfonyl)phenyl]-4-oxo-3,4-dihydroquinazolin-2-yl}ethyl]acetamide, Matrix protein p17 | | Authors: | Goldstone, D.C, Barnett, M.J, Taka, J.R.H. | | Deposit date: | 2023-08-04 | | Release date: | 2023-12-20 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Discovery, Crystallographic Studies, and Mechanistic Investigations of Novel Phenylalanine Derivatives Bearing a Quinazolin-4-one Scaffold as Potent HIV Capsid Modulators.
J.Med.Chem., 66, 2023
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4K7T
 | | Structure of the ternary complex of bacitracin, zinc, and geranyl-pyrophosphate | | Descriptor: | GERANYL DIPHOSPHATE, SODIUM ION, ZINC ION, ... | | Authors: | Economou, N.J, Loll, P.J. | | Deposit date: | 2013-04-17 | | Release date: | 2013-08-14 | | Last modified: | 2013-10-16 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | High-resolution crystal structure reveals molecular details of target recognition by bacitracin.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4M6E
 | | The high resolution structure of tyrocidine A reveals an amphipathic dimer | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, METHANOL, tyrocidine A | | Authors: | Loll, P.J, Economou, N.J, Nahoum, V. | | Deposit date: | 2013-08-09 | | Release date: | 2014-03-19 | | Method: | X-RAY DIFFRACTION (0.95 Å) | | Cite: | The high resolution structure of tyrocidine A reveals an amphipathic dimer.
Biochim.Biophys.Acta, 1838, 2014
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3RUM
 | | New strategy to analyze structures of glycopeptide antibiotic-target complexes | | Descriptor: | 3-amino-2,3,6-trideoxy-alpha-L-ribo-hexopyranose, ISOPROPYL ALCOHOL, Maltose-binding periplasmic protein, ... | | Authors: | Economou, N.J, Weeks, S.D, Grasty, K.C, Nahoum, V, Loll, P.J. | | Deposit date: | 2011-05-05 | | Release date: | 2012-06-06 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.851 Å) | | Cite: | A carrier protein strategy yields the structure of dalbavancin.
J.Am.Chem.Soc., 134, 2012
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3RUL
 | | New strategy to analyze structures of glycopeptide-target complexes | | Descriptor: | 10-METHYLUNDECANOIC ACID, 2-amino-2-deoxy-beta-D-glucopyranuronic acid, CHLORIDE ION, ... | | Authors: | Economou, N.J, Nahoum, V, Weeks, S.D, Grasty, K.C, Loll, P.J. | | Deposit date: | 2011-05-05 | | Release date: | 2012-06-06 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A carrier protein strategy yields the structure of dalbavancin.
J.Am.Chem.Soc., 134, 2012
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3RUN
 | | New strategy to analyze structures of glycopeptide antibiotic-target complexes | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | Authors: | Economou, N.J, Townsend, T.M, Loll, P.J. | | Deposit date: | 2011-05-05 | | Release date: | 2012-06-06 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | A carrier protein strategy yields the structure of dalbavancin.
J.Am.Chem.Soc., 134, 2012
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3VFK
 | | The structure of monodechloro-teicoplanin in complex with its ligand, using ubiquitin as a ligand carrier | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, 8-METHYLNONANOIC ACID, ... | | Authors: | Economou, N.J, Weeks, S.D, Grasty, K.C, Loll, P.J. | | Deposit date: | 2012-01-09 | | Release date: | 2013-01-09 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of the complex between teicoplanin and a bacterial cell-wall peptide: use of a carrier-protein approach.
Acta Crystallogr.,Sect.D, 69, 2013
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3VFJ
 | | The structure of monodechloro-teicoplanin in complex with its ligand, using MBP as a ligand carrier | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, 8-METHYLNONANOIC ACID, ... | | Authors: | Economou, N.J, Weeks, S.D, Grasty, K.C, Loll, P.J. | | Deposit date: | 2012-01-09 | | Release date: | 2013-01-09 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structure of the complex between teicoplanin and a bacterial cell-wall peptide: use of a carrier-protein approach.
Acta Crystallogr.,Sect.D, 69, 2013
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