Author results

2BUG
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SOLUTION STRUCTURE OF THE TPR DOMAIN FROM PROTEIN PHOSPHATASE 5 IN COMPLEX WITH HSP90 DERIVED PEPTIDE
Descriptor:SERINE/THREONINE PROTEIN PHOSPHATASE 5, HSP90
Authors:Cliff, M.J., Harris, R., Barford, D., Ladbury, J.E., Williams, M.A.
Deposit date:2005-06-13
Release date:2006-03-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Conformational Diversity in the Tpr Domain-Mediated Interaction of Protein Phosphatase 5 with Hsp90.
Structure, 14, 2006
2WZB
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THE CATALYTICALLY ACTIVE FULLY CLOSED CONFORMATION OF HUMAN PHOSPHOGLYCERATE KINASE IN COMPLEX WITH ADP, 3PG AND MAGNESIUM TRIFLUORIDE
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Bowler, M.W., Cliff, M.J., Marston, J.P.M., Baxter, N.J., Hownslow, A.M.H., Varga, A.V., Szabo, J., Vas, M., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-11-27
Release date:2010-04-14
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Transition State Analogue Structures of Human Phosphoglycerate Kinase Establish the Importance of Charge Balance in Catalysis.
J.Am.Chem.Soc., 132, 2010
2WZC
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THE CATALYTICALLY ACTIVE FULLY CLOSED CONFORMATION OF HUMAN PHOSPHOGLYCERATE KINASE IN COMPLEX WITH ADP, 3PG AND ALUMINIUM TETRAFLUORIDE
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Bowler, M.W., Cliff, M.J., Marston, J.P.M., Baxter, N.J., Hownslow, A.M.H., Varga, A.V., Szabo, J., Vas, M., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-11-27
Release date:2010-04-14
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Transition State Analogue Structures of Human Phosphoglycerate Kinase Establish the Importance of Charge Balance in Catalysis.
J.Am.Chem.Soc., 132, 2010
2WZD
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THE CATALYTICALLY ACTIVE FULLY CLOSED CONFORMATION OF HUMAN PHOSPHOGLYCERATE KINASE K219A MUTANT IN COMPLEX WITH ADP, 3PG AND ALUMINIUM TRIFLUORIDE
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Bowler, M.W., Cliff, M.J., Marston, J.P.M., Baxter, N.J., Hownslow, A.M.H., Varga, A.V., Szabo, J., Vas, M., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-11-27
Release date:2010-04-14
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Transition State Analogue Structures of Human Phosphoglycerate Kinase Establish the Importance of Charge Balance in Catalysis.
J.Am.Chem.Soc., 132, 2010
2WF5
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STRUCTURE OF BETA-PHOSPHOGLUCOMUTASE INHIBITED WITH GLUCOSE-6-PHOSPHATE AND TRIFLUOROMAGNESATE
Descriptor:BETA-PHOSPHOGLUCOMUTASE, BETA-D-GLUCOSE-6-PHOSPHATE, MAGNESIUM ION, ...
Authors:Bowler, M.W., Baxter, N.J., Webster, C.E., Hounslow, A.M., Cliff, M.J., Williams, N.H., Hollfelder, F., Gamblin, S., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-04-03
Release date:2009-09-15
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by MgF-3 rather than by phosphoranes.
Proc. Natl. Acad. Sci. U.S.A., 107, 2010
2WF6
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STRUCTURE OF BETA-PHOSPHOGLUCOMUTASE INHIBITED WITH GLUCOSE-6-PHOSPHATE AND ALUMINIUM TETRAFLUORIDE
Descriptor:BETA-PHOSPHOGLUCOMUTASE, TETRAFLUOROALUMINATE ION, MAGNESIUM ION, ...
Authors:Bowler, M.W., Baxter, N.J., Webster, C.E., Pollard, S., Alizadeh, T., Hounslow, A.M., Cliff, M.J., Bermel, W., Williams, N.H., Hollfelder, F., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-04-03
Release date:2010-05-26
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Atomic details of near-transition state conformers for enzyme phosphoryl transfer revealed by MgF-3 rather than by phosphoranes.
Proc. Natl. Acad. Sci. U.S.A., 107, 2010
2WF7
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STRUCTURE OF BETA-PHOSPHOGLUCOMUTASE INHIBITED WITH GLUCOSE-6- PHOSPHONATE AND ALUMINIUM TETRAFLUORIDE
Descriptor:BETA-PHOSPHOGLUCOMUTASE, TETRAFLUOROALUMINATE ION, MAGNESIUM ION, ...
Authors:Bowler, M.W., Baxter, N.J., Webster, C.E., Pollard, S., Alizadeh, T., Hounslow, A.M., Cliff, M.J., Bermel, W., Williams, N.H., Hollfelder, F., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-04-03
Release date:2010-05-19
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Alpha-Fluorophosphonates Reveal How a Phosphomutase Conserves Transition State Conformation Over Hexose Recognition in its Two-Step Reaction.
Proc.Natl.Acad.Sci.USA, 111, 2014
2WF8
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STRUCTURE OF BETA-PHOSPHOGLUCOMUTASE INHIBITED WITH GLUCOSE-6- PHOSPHATE, GLUCOSE-1-PHOSPHATE AND BERYLLIUM TRIFLUORIDE
Descriptor:BETA-PHOSPHOGLUCOMUTASE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Bowler, M.W., Baxter, N.J., Webster, C.E., Pollard, S., Alizadeh, T., Hounslow, A.M., Cliff, M.J., Bermel, W., Williams, N.H., Hollfelder, F., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-04-03
Release date:2010-05-26
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Near attack conformers dominate beta-phosphoglucomutase complexes where geometry and charge distribution reflect those of substrate.
Proc. Natl. Acad. Sci. U.S.A., 109, 2012
2WF9
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STRUCTURE OF BETA-PHOSPHOGLUCOMUTASE INHIBITED WITH GLUCOSE-6- PHOSPHATE, AND BERYLLIUM TRIFLUORIDE, CRYSTAL FORM 2
Descriptor:BETA-PHOSPHOGLUCOMUTASE, MAGNESIUM ION, ALPHA-D-GLUCOSE-6-PHOSPHATE, ...
Authors:Bowler, M.W., Baxter, N.J., Webster, C.E., Pollard, S., Alizadeh, T., Hounslow, A.M., Cliff, M.J., Bermel, W., Williams, N.H., Hollfelder, F., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-04-03
Release date:2010-05-26
Last modified:2012-05-16
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Near Attack Conformers Dominate Beta-Phosphoglucomutase Complexes Where Geometry and Charge Distribution Reflect Those of Substrate.
Proc.Natl.Acad.Sci.USA, 109, 2012
2WFA
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STRUCTURE OF BETA-PHOSPHOGLUCOMUTASE INHIBITED WITH BERYLLIUM TRIFLUORIDE, IN AN OPEN CONFORMATION.
Descriptor:BETA-PHOSPHOGLUCOMUTASE, MAGNESIUM ION, BERYLLIUM TRIFLUORIDE ION
Authors:Bowler, M.W., Baxter, N.J., Webster, C.E., Pollard, S., Alizadeh, T., Hounslow, A.M., Cliff, M.J., Bermel, W., Williams, N.H., Hollfelder, F., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-04-03
Release date:2010-05-26
Last modified:2012-05-16
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Near Attack Conformers Dominate Beta-Phosphoglucomutase Complexes Where Geometry and Charge Distribution Reflect Those of Substrate.
Proc.Natl.Acad.Sci.USA, 109, 2012
2WHE
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STRUCTURE OF NATIVE BETA-PHOSPHOGLUCOMUTASE IN AN OPEN CONFORMATION WITHOUT BOUND LIGANDS.
Descriptor:BETA-PHOSPHOGLUCOMUTASE, MAGNESIUM ION
Authors:Bowler, M.W., Baxter, N.J., Webster, C.E., Pollard, S., Alizadeh, T., Hounslow, A.M., Cliff, M.J., Bermel, W., Williams, N.H., Hollfelder, F., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-05-04
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Atomic Details of Near-Transition State Conformers for Enzyme Phosphoryl Transfer Revealed by Mgf-3 Rather Than by Phosphoranes.
Proc.Natl.Acad.Sci.USA, 107, 2010
2X13
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THE CATALYTICALLY ACTIVE FULLY CLOSED CONFORMATION OF HUMAN PHOSPHOGLYCERATE KINASE IN COMPLEX WITH ADP AND 3PHOSPHOGLYCERATE
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, 3-PHOSPHOGLYCERIC ACID, ...
Authors:Bowler, M.W., Cliff, M.J., Marston, J.P.M., Baxter, N.J., Hownslow, A.M.H., Varga, A.V., Szabo, J., Vas, M., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-12-21
Release date:2010-12-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:The Structure of Human Phosphoglycerate Kinase in its Fully Active Conformation with Ground State Analogues
To be Published
2X14
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THE CATALYTICALLY ACTIVE FULLY CLOSED CONFORMATION OF HUMAN PHOSPHOGLYCERATE KINASE K219A MUTANT IN COMPLEX WITH AMP-PCP AND 3PG
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, 3-PHOSPHOGLYCERIC ACID, ...
Authors:Bowler, M.W., Cliff, M.J., Marston, J.P.M., Baxter, N.J., Hownslow, A.M.H., Varga, A.V., Szabo, J., Vas, M., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-12-21
Release date:2010-12-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Structure of Human Phosphoglycerate Kinase in its Fully Active Conformation in Complex with Ground State Analogues
To be Published
2X15
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THE CATALYTICALLY ACTIVE FULLY CLOSED CONFORMATION OF HUMAN PHOSPHOGLYCERATE KINASE IN COMPLEX WITH ADP AND 1,3- BISPHOSPHOGLYCERATE
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Bowler, M.W., Cliff, M.J., Marston, J.P.M., Baxter, N.J., Hounslow, A.M.H., Varga, A.V., Szabo, J., Vas, M., Blackburn, G.M., Waltho, J.P.
Deposit date:2009-12-21
Release date:2011-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Structure of Human Phosphoglycerate Kinase in its Fully Active Conformation in Complex with Ground State Analoges
To be Published
5M0A
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SOLUTION STRUCTURE OF ISOLATED 15TH FIBRONECTIN III DOMAIN FROM HUMAN FIBRONECTIN
Descriptor:Fibronectin
Authors:Waltho, J.P., Cliff, M.J., Blumson, E., Humphries, M.
Deposit date:2016-10-04
Release date:2017-11-29
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Solution structure of isolated 15th Fibronectin III domain from human fibronectin
To Be Published
2XE6
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THE COMPLETE REACTION CYCLE OF HUMAN PHOSPHOGLYCERATE KINASE: THE OPEN BINARY COMPLEX WITH 3PG
Descriptor:PHOSPHOGLYCERATE KINASE 1, 3-PHOSPHOGLYCERIC ACID
Authors:Cliff, M.J., Baxter, N.J., Blackburn, G.M., Merli, A., Vas, M., Waltho, J.P., Bowler, M.W.
Deposit date:2010-05-11
Release date:2011-01-19
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:A Spring Loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase.
J.Biol.Chem., 286, 2011
2XE7
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THE COMPLETE REACTION CYCLE OF HUMAN PHOSPHOGLYCERATE KINASE: THE OPEN TERNARY COMPLEX WITH 3PG AND ADP
Descriptor:PHOSPHOGLYCERATE KINASE 1, 3-PHOSPHOGLYCERIC ACID, ADENOSINE-5'-DIPHOSPHATE
Authors:Cliff, M.J., Baxter, N.J., Blackburn, G.M., Merli, A., Vas, M., Waltho, J.P., Bowler, M.W.
Deposit date:2010-05-11
Release date:2011-01-19
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Spring Loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase.
J.Biol.Chem., 286, 2011
2XE8
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THE COMPLETE REACTION CYCLE OF HUMAN PHOSPHOGLYCERATE KINASE: THE OPEN TERNARY COMPLEX WITH 3PG AND AMP-PNP
Descriptor:PHOSPHOGLYCERATE KINASE 1, 3-PHOSPHOGLYCERIC ACID, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
Authors:Cliff, M.J., Baxter, N.J., Blackburn, G.M., Merli, A., Vas, M., Waltho, J.P., Bowler, M.W.
Deposit date:2010-05-11
Release date:2011-01-19
Last modified:2011-10-26
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:A Spring Loaded Release Mechanism Regulates Domain Movement and Catalysis in Phosphoglycerate Kinase.
J.Biol.Chem., 286, 2011
1Q31
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CRYSTAL STRUCTURE OF THE TOBACCO ETCH VIRUS PROTEASE C151A MUTANT
Descriptor:Nuclear inclusion protein A, BETA-MERCAPTOETHANOL
Authors:Nunn, C.M., Djordjevic, S., George, R.R., Urquhart, G.T., Chao, L.H., Tsuchiya, Y.
Deposit date:2003-07-28
Release date:2004-11-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of tobacco etch virus protease shows the protein C terminus bound within the active site.
J.Mol.Biol., 350, 2005
1WAO
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PP5 STRUCTURE
Descriptor:SERINE/THREONINE PROTEIN PHOSPHATASE 5, MANGANESE (II) ION
Authors:Barford, D.
Deposit date:2004-10-27
Release date:2005-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular Basis for Tpr Domain-Mediated Regulation of Protein Phosphatase 5
Embo J., 24, 2005
4AXX
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THE CATALYTICALLY ACTIVE FULLY CLOSED CONFORMATION OF HUMAN PHOSPHOGLYCERATE KINASE IN COMPLEX WITH ADP 3-PHOSPHOGLYCERATE AND BERYLLIUM TRIFLUORIDE
Descriptor:PHOSPHOGLYCERATE KINASE 1, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Bowler, M.W.
Deposit date:2012-06-15
Release date:2013-06-26
Last modified:2013-10-02
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Catalytic Activity in the Transitions State Analogue Stabilised Conformation of a Phosphoryl Transfer Enzyme
To be Published
4C4R
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STRUCTURE OF BETA-PHOSPHOGLUCOMUTASE IN COMPLEX WITH A PHOSPHONATE ANALOGUE OF BETA-GLUCOSE-1-PHOSPHATE AND MAGNESIUM TRIFLUORIDE
Descriptor:BETA-PHOSPHOGLUCOMUTASE, MAGNESIUM ION, Beta-1 phosphonomethylene-D-glucopyranose, ...
Authors:Pellegrini, E., Bowler, M.W.
Deposit date:2013-09-09
Release date:2014-07-16
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Alpha-Fluorophosphonates Reveal How a Phosphomutase Conserves Transition State Conformation Over Hexose Recognition in its Two-Step Reaction.
Proc.Natl.Acad.Sci.USA, 111, 2014
4C4S
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STRUCTURE OF BETA-PHOSPHOGLUCOMUTASE IN COMPLEX WITH AN ALPHA- FLUOROPHOSPHONATE ANALOGUE OF BETA-GLUCOSE-1-PHOSPHATE AND MAGNESIUM TRIFLUORIDE
Descriptor:BETA-PHOSPHOGLUCOMUTASE, (S)-1-beta-phosphonofluoromethylene-1-deoxy-D-glucopyranose, TRIFLUOROMAGNESATE, ...
Authors:Pellegrini, E., Bowler, M.W.
Deposit date:2013-09-09
Release date:2014-07-16
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Alpha-Fluorophosphonates Reveal How a Phosphomutase Conserves Transition State Conformation Over Hexose Recognition in its Two-Step Reaction.
Proc.Natl.Acad.Sci.USA, 111, 2014
4C4T
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STRUCTURE OF BETA-PHOSPHOGLUCOMUTASE IN COMPLEX WITH A PHOSPHONATE ANALOGUE OF BETA-GLUCOSE-1-PHOSPHATE AND ALUMINIUM TETRAFLUORIDE
Descriptor:BETA-PHOSPHOGLUCOMUTASE, (S)-1-beta-phosphonofluoromethylene-1-deoxy-D-glucopyranose, TETRAFLUOROALUMINATE ION, ...
Authors:Pellegrini, E., Bowler, M.W.
Deposit date:2013-09-09
Release date:2014-07-16
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Alpha-Fluorophosphonates Reveal How a Phosphomutase Conserves Transition State Conformation Over Hexose Recognition in its Two-Step Reaction.
Proc.Natl.Acad.Sci.USA, 111, 2014
4JB0
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RHODOPSEUDOMONAS PALUSTRIS (STRAIN CGA009) RP1789 TRANSPORT PROTEIN
Descriptor:branched-chain amino acid transport system substrate-binding protein, 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, ...
Authors:Salmon, R.
Deposit date:2013-02-19
Release date:2013-04-17
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:The CouPSTU and TarPQM Transporters in Rhodopseudomonas palustris: Redundant, Promiscuous Uptake Systems for Lignin-Derived Aromatic Substrates.
Plos One, 8, 2013
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