Author results

1GG6
  • Download 1gg6
  • View 1gg6
Molmil generated image of 1gg6
CRYSTAL STRUCTURE OF GAMMA CHYMOTRYPSIN WITH N-ACETYL-PHENYLALANINE TRIFLUOROMETHYL KETONE BOUND AT THE ACTIVE SITE
Descriptor:GAMMA CHYMOTRYPSIN, SULFATE ION, N-(1-BENZYL-3,3,3-TRIFLUORO-2,2-DIHYDROXY-PROPYL)-ACETAMIDE, ...
Authors:Neidhart, D., Wei, Y., Cassidy, C., Lin, J., Cleland, W.W., Frey, P.A.
Deposit date:2000-07-31
Release date:2000-09-20
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Correlation of low-barrier hydrogen bonding and oxyanion binding in transition state analogue complexes of chymotrypsin.
Biochemistry, 40, 2001
1GGD
  • Download 1ggd
  • View 1ggd
Molmil generated image of 1ggd
CRYSTAL STRUCTURE OF GAMMA CHYMOTRYPSIN WITH N-ACETYL-LEUCIL-PHENYLALANINE ALDEHYDE BOUND AT THE ACTIVE SITE
Descriptor:GAMMA CHYMOTRYPSIN, SULFATE ION, 2-ACETYLAMINO-4-METHYL-PENTANOIC ACID (1-FORMYL-2-PHENYL-ETHYL)-AMIDE
Authors:Neidhart, D., Wei, Y., Cassidy, C., Lin, J., Cleland, W.W., Frey, P.A.
Deposit date:2000-08-14
Release date:2000-09-20
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Correlation of low-barrier hydrogen bonding and oxyanion binding in transition state analogue complexes of chymotrypsin.
Biochemistry, 40, 2000
1P43
  • Download 1p43
  • View 1p43
Molmil generated image of 1p43
REVERSE PROTONATION IS THE KEY TO GENERAL ACID-BASE CATALYSIS IN ENOLASE
Descriptor:Enolase 1, MAGNESIUM ION, 2-PHOSPHOGLYCERIC ACID
Authors:Sims, P.A., Larsen, T.M., Poyner, R.R., Cleland, W.W., Reed, G.H.
Deposit date:2003-04-21
Release date:2003-11-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Reverse protonation is the key to general acid-base catalysis in enolase
Biochemistry, 42, 2003
1P48
  • Download 1p48
  • View 1p48
Molmil generated image of 1p48
REVERSE PROTONATION IS THE KEY TO GENERAL ACID-BASE CATALYSIS IN ENOLASE
Descriptor:Enolase 1, MAGNESIUM ION, PHOSPHOENOLPYRUVATE
Authors:Sims, P.A., Larsen, T.M., Poyner, R.R., Cleland, W.W., Reed, G.H.
Deposit date:2003-04-21
Release date:2003-11-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Reverse protonation is the key to general acid-base catalysis in enolase
Biochemistry, 42, 2003
1R66
  • Download 1r66
  • View 1r66
Molmil generated image of 1r66
CRYSTAL STRUCTURE OF DESIV (DTDP-GLUCOSE 4,6-DEHYDRATASE) FROM STREPTOMYCES VENEZUELAE WITH NAD AND TYD BOUND
Descriptor:TDP-glucose-4,6-dehydratase, CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Allard, S.T.M., Cleland, W.W., Holden, H.M.
Deposit date:2003-10-14
Release date:2004-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:High Resolution X-ray Structure of dTDP-Glucose 4,6-Dehydratase from Streptomyces venezuelae
J.Biol.Chem., 279, 2004
1R6D
  • Download 1r6d
  • View 1r6d
Molmil generated image of 1r6d
CRYSTAL STRUCTURE OF DESIV DOUBLE MUTANT (DTDP-GLUCOSE 4,6-DEHYDRATASE) FROM STREPTOMYCES VENEZUELAE WITH NAD AND DAU BOUND
Descriptor:TDP-glucose-4,6-dehydratase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 2'DEOXY-THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE
Authors:Allard, S.T.M., Cleland, W.W., Holden, H.M.
Deposit date:2003-10-14
Release date:2004-01-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:High Resolution X-ray Structure of dTDP-Glucose 4,6-Dehydratase from Streptomyces venezuelae
J.Biol.Chem., 279, 2004
1WVC
  • Download 1wvc
  • View 1wvc
Molmil generated image of 1wvc
ALPHA-D-GLUCOSE-1-PHOSPHATE CYTIDYLYLTRANSFERASE COMPLEXED WITH CTP
Descriptor:Glucose-1-phosphate cytidylyltransferase, MAGNESIUM ION, NICKEL (II) ION, ...
Authors:Koropatkin, N.M., Cleland, W.W., Holden, H.M.
Deposit date:2004-12-14
Release date:2005-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Kinetic and structural analysis of alpha-D-Glucose-1-phosphate cytidylyltransferase from Salmonella typhi.
J.Biol.Chem., 280, 2005
3S0M
  • Download 3s0m
  • View 3s0m
Molmil generated image of 3s0m
A STRUCTURAL ELEMENT THAT MODULATES PROTON-COUPLED ELECTRON TRANSFER IN OXALATE DECARBOXYLASE
Descriptor:Oxalate decarboxylase oxdC, MANGANESE (II) ION, CARBONATE ION, ...
Authors:Saylor, B.T., Reinhardt, L.A., Lu, Z., Shukla, M.S., Cleland, W.W., Allen, K.N., Richards, N.G.J.
Deposit date:2011-05-13
Release date:2012-04-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:A structural element that facilitates proton-coupled electron transfer in oxalate decarboxylase.
Biochemistry, 51, 2012
4EA7
  • Download 4ea7
  • View 4ea7
Molmil generated image of 4ea7
X-RAY CRYSTAL STRUCTURE OF PERB FROM CAULOBACTER CRESCENTUS IN COMPLEX WITH COA AND GDP-PEROSAMINE AT 1.0 ANGSTROM RESOLUTION
Descriptor:Perosamine N-acetyltransferase, COENZYME A, GDP-perosamine, ...
Authors:Thoden, J.B., Reinhardt, L.A., Cook, P.D., Menden, P., Cleland, W.W., Holden, H.M.
Deposit date:2012-03-22
Release date:2012-04-04
Last modified:2012-12-26
Method:X-RAY DIFFRACTION (1 Å)
Cite:Catalytic Mechanism of Perosamine N-Acetyltransferase Revealed by High-Resolution X-ray Crystallographic Studies and Kinetic Analyses.
Biochemistry, 51, 2012
4EA8
  • Download 4ea8
  • View 4ea8
Molmil generated image of 4ea8
X-RAY CRYSTAL STRUCTURE OF PERB FROM CAULOBACTER CRESCENTUS IN COMPLEX WITH COENZYME A AND GDP-N-ACETYLPEROSAMINE AT 1 ANGSTROM RESOLUTION
Descriptor:Perosamine N-acetyltransferase, COENZYME A, GDP-N-acetylperosamine, ...
Authors:Thoden, J.B., Reinhardt, L.A., Cook, P.D., Menden, P., Cleland, W.W., Holden, H.M.
Deposit date:2012-03-22
Release date:2012-04-04
Last modified:2012-12-26
Method:X-RAY DIFFRACTION (1 Å)
Cite:Catalytic Mechanism of Perosamine N-Acetyltransferase Revealed by High-Resolution X-ray Crystallographic Studies and Kinetic Analyses.
Biochemistry, 51, 2012
4EA9
  • Download 4ea9
  • View 4ea9
Molmil generated image of 4ea9
X-RAY STRUCTURE OF GDP-PEROSAMINE N-ACETYLTRANSFERASE IN COMPLEX WITH TRANSITION STATE ANALOG AT 0.9 ANGSTROM RESOLUTION
Descriptor:Perosamine N-acetyltransferase, GDP-N-acetylperosamine-coenzyme A, CHLORIDE ION
Authors:Thoden, J.B., Reinhardt, L.A., Cook, P.D., Menden, P., Cleland, W.W., Holden, H.M.
Deposit date:2012-03-22
Release date:2012-04-04
Last modified:2012-12-26
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:Catalytic Mechanism of Perosamine N-Acetyltransferase Revealed by High-Resolution X-ray Crystallographic Studies and Kinetic Analyses.
Biochemistry, 51, 2012
4EAA
  • Download 4eaa
  • View 4eaa
Molmil generated image of 4eaa
X-RAY CRYSTAL STRUCTURE OF THE H141N MUTANT OF PEROSAMINE N-ACETYLTRANSFERASE FROM CAULOBACTER CRESCENTUS IN COMPLEX WITH COA AND GDP-PEROSAMINE
Descriptor:Perosamine N-acetyltransferase, GDP-perosamine, COENZYME A, ...
Authors:Thoden, J.B., Reinhardt, L.A., Cook, P.D., Menden, P., Cleland, W.W., Holden, H.M.
Deposit date:2012-03-22
Release date:2012-04-04
Last modified:2012-12-26
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Catalytic Mechanism of Perosamine N-Acetyltransferase Revealed by High-Resolution X-ray Crystallographic Studies and Kinetic Analyses.
Biochemistry, 51, 2012
4EAB
  • Download 4eab
  • View 4eab
Molmil generated image of 4eab
X-RAY CRYSTAL STRUCTURE OF THE H141A MUTANT OF GDP-PEROSAMINE N-ACETYL TRANSFERASE FROM CAULOBACTER CRESCENTUS IN COMPLEX WITH COA AND GDP-PEROSAMINE
Descriptor:Perosamine N-acetyltransferase, GDP-perosamine, COENZYME A, ...
Authors:Thoden, J.B., Reinhardt, L.A., Cook, P.D., Menden, P., Cleland, W.W., Holden, H.M.
Deposit date:2012-03-22
Release date:2012-04-04
Last modified:2012-12-26
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Catalytic Mechanism of Perosamine N-Acetyltransferase Revealed by High-Resolution X-ray Crystallographic Studies and Kinetic Analyses.
Biochemistry, 51, 2012
2QF7
  • Download 2qf7
  • View 2qf7
Molmil generated image of 2qf7
CRYSTAL STRUCTURE OF A COMPLETE MULTIFUNCTIONAL PYRUVATE CARBOXYLASE FROM RHIZOBIUM ETLI
Descriptor:Pyruvate carboxylase protein, MAGNESIUM ION, ZINC ION, ...
Authors:St Maurice, M., Surinya, K.H., Rayment, I.
Deposit date:2007-06-27
Release date:2007-09-04
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme
Science, 317, 2007
3TW6
  • Download 3tw6
  • View 3tw6
Molmil generated image of 3tw6
STRUCTURE OF RHIZOBIUM ETLI PYRUVATE CARBOXYLASE T882A WITH THE ALLOSTERIC ACTIVATOR, ACETYL COENZYME-A
Descriptor:Pyruvate carboxylase protein, CHLORIDE ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:St Maurice, M., Kumar, S., Lietzan, A.D.
Deposit date:2011-09-21
Release date:2011-10-19
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli.
Biochemistry, 50, 2011
3TW7
  • Download 3tw7
  • View 3tw7
Molmil generated image of 3tw7
STRUCTURE OF RHIZOBIUM ETLI PYRUVATE CARBOXYLASE T882A CRYSTALLIZED WITHOUT ACETYL COENZYME-A
Descriptor:Pyruvate carboxylase protein, MAGNESIUM ION, ZINC ION, ...
Authors:St Maurice, M., Kumar, S., Lietzan, A.D.
Deposit date:2011-09-21
Release date:2011-10-12
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli.
Biochemistry, 50, 2011
3V8E
  • Download 3v8e
  • View 3v8e
Molmil generated image of 3v8e
CRYSTAL STRUCTURE OF THE YEAST NICOTINAMIDASE PNC1P BOUND TO THE INHIBITOR NICOTINALDEHYDE
Descriptor:Nicotinamidase, ZINC ION, MAGNESIUM ION
Authors:Hoadley, K.A., Smith, B.C., Denu, J.M., Keck, J.L.
Deposit date:2011-12-22
Release date:2012-01-25
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structural and Kinetic Isotope Effect Studies of Nicotinamidase (Pnc1) from Saccharomyces cerevisiae.
Biochemistry, 51, 2012
1FNJ
  • Download 1fnj
  • View 1fnj
Molmil generated image of 1fnj
CRYSTAL STRUCTURE ANALYSIS OF CHORISMATE MUTASE MUTANT C88S/R90K
Descriptor:PROTEIN (CHORISMATE MUTASE)
Authors:Kast, P., Grisostomi, C., Chen, I.A., Li, S., Krengel, U., Xue, Y., Hilvert, D.
Deposit date:2000-08-22
Release date:2000-10-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A strategically positioned cation is crucial for efficient catalysis by chorismate mutase.
J.Biol.Chem., 275, 2000
1FNK
  • Download 1fnk
  • View 1fnk
Molmil generated image of 1fnk
CRYSTAL STRUCTURE ANALYSIS OF CHORISMATE MUTASE MUTANT C88K/R90S
Descriptor:PROTEIN (CHORISMATE MUTASE)
Authors:Kast, P., Grisostomi, C., Chen, I.A., Li, S., Krengel, U., Xue, Y., Hilvert, D.
Deposit date:2000-08-22
Release date:2000-10-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:A strategically positioned cation is crucial for efficient catalysis by chorismate mutase.
J.Biol.Chem., 275, 2000