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2MPM
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STRUCTURAL BASIS OF RECEPTOR SULFOTYROSINE RECOGNITION BY A CC CHEMOKINE: THE N-TERMINAL REGION OF CCR3 BOUND TO CCL11/EOTAXIN-1
Descriptor:Eotaxin, CCR3
Authors:Millard, C.J., Ludeman, J.P., Canals, M., Bridgford, J.L., Hinds, M.G., Clayton, D.J., Christopoulos, A., Payne, R.J., Stone, M.J.
Deposit date:2014-05-26
Release date:2014-12-10
Method:SOLUTION NMR
Cite:Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: The N-Terminal Region of CCR3 Bound to CCL11/Eotaxin-1.
Structure, 22, 2014
4DHL
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CRYSTAL STRUCTURE OF RED KIDNEY BEAN PURPLE ACID PHOSPHATASE IN COMPLEX WITH MAYBRIDGE FRAGMENT MO07123
Descriptor:Purple acid phosphatase, ZINC ION, FE (III) ION, ...
Authors:Feder, D., Clayton, D.J., Hussein, W.M., Schenk, G., McGeary, R., Guddat, L.W.
Deposit date:2012-01-29
Release date:2012-12-12
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics.
Chem.Biol.Drug Des., 80, 2012
4DSY
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CRYSTAL STRUCTURE OF RED KIDNEY BEAN PURPLE ACID PHOSPHATASE IN COMPLEX WITH MAYBRIDGE FRAGMENT CC24201
Descriptor:Purple acid phosphatase, ZINC ION, FE (III) ION, ...
Authors:Feder, D., Hussein, W.M., Clayton, D.J., Kan, M., Schenk, G., McGeary, R.P., Guddat, L.W.
Deposit date:2012-02-20
Release date:2012-09-19
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics.
Chem.Biol.Drug Des., 80, 2012
4DT2
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CRYSTAL STRUCTURE OF RED KIDNEY BEAN PURPLE ACID PHOSPHATASE IN COMPLEX WITH MAYBRIDGE FRAGMENT CC27209
Descriptor:Purple acid phosphatase, ZINC ION, FE (III) ION, ...
Authors:Feder, D., Hussein, W.M., Clayton, D.J., Kan, M., Schenk, G., McGeary, R.P., Guddat, L.W.
Deposit date:2012-02-20
Release date:2012-09-19
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics.
Chem.Biol.Drug Des., 80, 2012
1F8Z
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NMR STRUCTURE OF THE SIXTH LIGAND-BINDING MODULE OF THE LDL RECEPTOR
Descriptor:LOW-DENSITY LIPOPROTEIN RECEPTOR, CALCIUM ION
Authors:Clayton, D.J., Brereton, I.M., Kroon, P.A., Smith, R.
Deposit date:2000-07-05
Release date:2000-10-18
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional NMR structure of the sixth ligand-binding module of the human LDL receptor: comparison of two adjacent modules with different ligand binding specificities.
FEBS Lett., 479, 2000
2MG9
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TRUNCATED EGF-A
Descriptor:Low-density lipoprotein receptor, CALCIUM ION
Authors:Schroeder, C.I., Rosengren, K.
Deposit date:2013-10-30
Release date:2014-04-02
Method:SOLUTION NMR
Cite:Design and Synthesis of Truncated EGF-A Peptides that Restore LDL-R Recycling in the Presence of PCSK9 In Vitro.
Chem.Biol., 21, 2014
4NE9
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PCSK9 IN COMPLEX WITH LDLR PEPTIDE
Descriptor:Proprotein convertase subtilisin/kexin type 9, Low-density lipoprotein receptor, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Liu, S.
Deposit date:2013-10-28
Release date:2014-09-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro.
Chem.Biol., 21, 2014
3PQZ
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GRB7 SH2 WITH PEPTIDE
Descriptor:Growth factor receptor-bound protein 7, cyclic peptide
Authors:Wilce, J.A.
Deposit date:2010-11-29
Release date:2011-07-20
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (2.413 Å)
Cite:Structural basis of binding by cyclic nonphosphorylated Peptide antagonists of grb7 implicated in breast cancer progression
J.Mol.Biol., 412, 2011