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1CL1
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CYSTATHIONINE BETA-LYASE (CBL) FROM ESCHERICHIA COLI
Descriptor:CYSTATHIONINE BETA-LYASE, BICARBONATE ION
Authors:Clausen, T., Huber, R., Messerschmidt, A.
Deposit date:1997-09-02
Release date:1998-09-09
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Crystal structure of the pyridoxal-5'-phosphate dependent cystathionine beta-lyase from Escherichia coli at 1.83 A.
J.Mol.Biol., 262, 1996
1CL2
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CYSTATHIONINE BETA-LYASE (CBL) FROM ESCHERICHIA COLI IN COMPLEX WITH AMINOETHOXYVINYLGLYCINE
Descriptor:CYSTATHIONINE BETA-LYASE, (2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid
Authors:Clausen, T., Huber, R., Messerschmidt, A.
Deposit date:1997-09-04
Release date:1998-09-09
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Slow-binding inhibition of Escherichia coli cystathionine beta-lyase by L-aminoethoxyvinylglycine: a kinetic and X-ray study.
Biochemistry, 36, 1997
1CS1
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CYSTATHIONINE GAMMA-SYNTHASE (CGS) FROM ESCHERICHIA COLI
Descriptor:PROTEIN (CYSTATHIONINE GAMMA-SYNTHASE), 2,4-DIOXO-PENTANEDIOIC ACID
Authors:Clausen, T., Messerschmidt, A.
Deposit date:1998-09-23
Release date:1999-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of Escherichia coli cystathionine gamma-synthase at 1.5 A resolution.
EMBO J., 17, 1998
1D2F
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X-RAY STRUCTURE OF MALY FROM ESCHERICHIA COLI: A PYRIDOXAL-5'-PHOSPHATE-DEPENDENT ENZYME ACTING AS A MODULATOR IN MAL GENE EXPRESSION
Descriptor:MALY PROTEIN, PYRIDOXAL-5'-PHOSPHATE
Authors:Clausen, T.
Deposit date:1999-09-23
Release date:2000-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray structure of MalY from Escherichia coli: a pyridoxal 5'-phosphate-dependent enzyme acting as a modulator in mal gene expression.
EMBO J., 19, 2000
1ELQ
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CRYSTAL STRUCTURE OF THE CYSTINE C-S LYASE C-DES
Descriptor:L-CYSTEINE/L-CYSTINE C-S LYASE, POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Clausen, T., Kaiser, J.T., Steegborn, C., Huber, R., Kessler, D.
Deposit date:2000-03-14
Release date:2000-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the cystine C-S lyase from Synechocystis: stabilization of cysteine persulfide for FeS cluster biosynthesis.
Proc.Natl.Acad.Sci.USA, 97, 2000
1ELU
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COMPLEX BETWEEN THE CYSTINE C-S LYASE C-DES AND ITS REACTION PRODUCT CYSTEINE PERSULFIDE.
Descriptor:L-CYSTEINE/L-CYSTINE C-S LYASE, POTASSIUM ION, 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-PROPIONIC ACID, ...
Authors:Clausen, T., Kaiser, J.T., Steegborn, C., Huber, R., Kessler, D.
Deposit date:2000-03-14
Release date:2000-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of the cystine C-S lyase from Synechocystis: stabilization of cysteine persulfide for FeS cluster biosynthesis.
Proc.Natl.Acad.Sci.USA, 97, 2000
4I2W
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CRYSTAL STRUCTURE OF THE MYOSIN CHAPERONE UNC-45 FROM C.ELEGANS IN COMPLEX WITH A HSP70 PEPTIDE
Descriptor:Protein UNC-45, Heat shock 70 kDa protein A
Authors:Clausen, T., Gazda, L., Hellerschmied, D.
Deposit date:2012-11-23
Release date:2013-03-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The myosin chaperone UNC-45 is organized in tandem modules to support myofilament formation in C. elegans.
Cell(Cambridge,Mass.), 152, 2013
4I2Z
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CRYSTAL STRUCTURE OF THE MYOSIN CHAPERONE UNC-45 FROM C.ELEGANS IN COMPLEX WITH A HSP90 PEPTIDE
Descriptor:Protein UNC-45, Heat shock protein 90
Authors:Clausen, T., Gazda, L., Hellerschmied, D.
Deposit date:2012-11-23
Release date:2013-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The myosin chaperone UNC-45 is organized in tandem modules to support myofilament formation in C. elegans.
Cell(Cambridge,Mass.), 152, 2013
2R3U
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CRYSTAL STRUCTURE OF THE PDZ DELETION MUTANT OF DEGS
Descriptor:Protease degS
Authors:Clausen, T., Kurzbauer, R.
Deposit date:2007-08-30
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress.
Genes Dev., 21, 2007
2R3Y
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CRYSTAL STRUCTURE OF THE DEGS PROTEASE IN COMPLEX WITH THE YWF ACTIVATING PEPTIDE
Descriptor:Protease degS, Synthetic peptide YWF
Authors:Clausen, T., Hasselblatt, H.
Deposit date:2007-08-30
Release date:2007-11-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress.
Genes Dev., 21, 2007
3H0D
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CRYSTAL STRUCTURE OF CTSR IN COMPLEX WITH A 26BP DNA DUPLEX
Descriptor:CtsR, DNA (26-MER), PHOSPHATE ION
Authors:Clausen, T., Fuhrmann, J.
Deposit date:2009-04-09
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR
Science, 324, 2009
3HGO
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CRYSTAL STRUCTURE OF THE F74Y/H244Y OPR3 DOUBLE MUTANT FROM TOMATO
Descriptor:12-oxophytodienoate reductase 3, FLAVIN MONONUCLEOTIDE
Authors:Clausen, T., Breithaupt, C.
Deposit date:2009-05-14
Release date:2009-08-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of substrate specificity of plant 12-oxophytodienoate reductases.
J.Mol.Biol., 392, 2009
3HGR
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CRYSTAL STRUCTURE OF TOMATO OPR1 IN COMPLEX WITH PHB
Descriptor:12-oxophytodienoate reductase 1, FLAVIN MONONUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Clausen, T., Breithaupt, C.
Deposit date:2009-05-14
Release date:2009-08-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of substrate specificity of plant 12-oxophytodienoate reductases.
J.Mol.Biol., 392, 2009
3HGS
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CRYSTAL STRUCTURE OF TOMATO OPR3 IN COMPLEX WITH PHB
Descriptor:12-oxophytodienoate reductase 3, FLAVIN MONONUCLEOTIDE, P-HYDROXYBENZOIC ACID
Authors:Clausen, T., Breithaupt, C.
Deposit date:2009-05-14
Release date:2009-08-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of substrate specificity of plant 12-oxophytodienoate reductases.
J.Mol.Biol., 392, 2009
3QO6
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CRYSTAL STRUCTURE ANALYSIS OF THE PLANT PROTEASE DEG1
Descriptor:Protease Do-like 1, chloroplastic, peptide
Authors:Clausen, T.
Deposit date:2011-02-09
Release date:2011-05-04
Last modified:2012-09-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural adaptation of the plant protease Deg1 to repair photosystem II during light exposure.
Nat.Struct.Mol.Biol., 18, 2011
4PIC
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YWLE ARGININE PHOSPHATASE FROM GEOBACILLUS STEAROTHERMOPHILUS
Descriptor:Arginine phosphatase Ywle, PHOSPHATE ION, SULFATE ION
Authors:Clausen, T., Fuhrmann, J.
Deposit date:2014-05-08
Release date:2014-05-28
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Chasing phosphoarginine proteins: development of a selective enrichment method using a phosphatase trap.
Mol.Cell Proteomics, 2014
1IXN
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ENZYME-SUBSTRATE COMPLEX OF PYRIDOXINE 5'-PHOSPHATE SYNTHASE
Descriptor:Pyridoxine 5'-Phosphate Synthase, 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, SN-GLYCEROL-3-PHOSPHATE
Authors:Garrido-Franco, M., Laber, B., Huber, R., Clausen, T.
Deposit date:2002-06-28
Release date:2003-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis
J.MOL.BIOL., 321, 2002
1IXO
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ENZYME-ANALOGUE SUBSTRATE COMPLEX OF PYRIDOXINE 5'-PHOSPHATE SYNTHASE
Descriptor:Pyridoxine 5'-Phosphate synthase, SN-GLYCEROL-3-PHOSPHATE
Authors:Garrido-Franco, M., Laber, B., Huber, R., Clausen, T.
Deposit date:2002-06-28
Release date:2003-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis
J.MOL.BIOL., 321, 2002
1IXP
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ENZYME-PHOSPHATE COMPLEX OF PYRIDOXINE 5'-PHOSPHATE SYNTHASE
Descriptor:Pyridoxine 5'-Phosphate synthase, PHOSPHATE ION
Authors:Garrido-Franco, M., Laber, B., Huber, R., Clausen, T.
Deposit date:2002-06-28
Release date:2003-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis
J.MOL.BIOL., 321, 2002
1IXQ
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ENZYME-PHOSPHATE2 COMPLEX OF PYRIDOXINE 5'-PHOSPHATE SYNTHASE
Descriptor:Pyridoxine 5'-phosphate Synthase, PHOSPHATE ION
Authors:Garrido-Franco, M., Laber, B., Huber, R., Clausen, T.
Deposit date:2002-06-28
Release date:2003-02-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis
J.MOL.BIOL., 321, 2002
4A8D
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DEGP DODECAMER WITH BOUND OMP
Descriptor:PERIPLASMIC SERINE ENDOPROTEASE DEGP, OUTER MEMBRANE PROTEIN C
Authors:Malet, H., Krojer, T., Sawa, J., Schafer, E., Saibil, H.R., Ehrmann, M., Clausen, T.
Deposit date:2011-11-20
Release date:2012-01-11
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (28 Å)
Cite:Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
5MZU
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CRYSTAL STRUCTURE OF THE MYOSIN CHAPERONE UNC-45 FROM C. ELEGANS (ALTERNATIVE CONFORMATION)
Descriptor:UNC-45
Authors:Hellerschmied, D., Gazda, L., Clausen, T.
Deposit date:2017-02-01
Release date:2018-02-14
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:UFD-2 is an adaptor-assisted E3 ligase targeting unfolded proteins.
Nat Commun, 9, 2018
1KY9
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CRYSTAL STRUCTURE OF DEGP (HTRA)
Descriptor:PROTEASE DO
Authors:Krojer, T., Garrido-Franco, M., Huber, R., Ehrmann, M., Clausen, T.
Deposit date:2002-02-04
Release date:2002-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine.
Nature, 416, 2002
3CS0
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CRYSTAL STRUCTURE OF DEGP24
Descriptor:Protease do, pentapeptide
Authors:Krojer, T., Sawa, J., Schaefer, E., Saibil, H.R., Ehrmann, M., Clausen, T.
Deposit date:2008-04-08
Release date:2008-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the regulated protease and chaperone function of DegP
Nature, 453, 2008
3MH4
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HTRA PROTEASES ARE ACTIVATED BY A CONSERVED MECHANISM THAT CAN BE TRIGGERED BY DISTINCT MOLECULAR CUES
Descriptor:Protease do
Authors:Krojer, T., Sawa, J., Huber, R., Clausen, T.
Deposit date:2010-04-07
Release date:2010-06-30
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues
Nat.Struct.Mol.Biol., 17, 2010