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1LPH
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BU of 1lph by Molmil
LYS(B28)PRO(B29)-HUMAN INSULIN
Descriptor: CHLORIDE ION, INSULIN, PHENOL, ...
Authors:Ciszak, E, Beals, J.M, Frank, B.H, Baker, J.C, Carter, N.D, Smith, G.D.
Deposit date:1995-04-19
Release date:1996-06-20
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Role of C-terminal B-chain residues in insulin assembly: the structure of hexameric LysB28ProB29-human insulin.
Structure, 3, 1995
1THC
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BU of 1thc by Molmil
CRYSTAL STRUCTURE DETERMINATION AT 2.3A OF HUMAN TRANSTHYRETIN-3',5'-DIBROMO-2',4,4',6-TETRA-HYDROXYAURONE COMPLEX
Descriptor: 3',5'-DIBROMO-2',4,4',6'-TETRAHYDROXY AURONE, TRANSTHYRETIN
Authors:Ciszak, E, Cody, V, Luft, J.R.
Deposit date:1992-04-20
Release date:1993-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure determination at 2.3-A resolution of human transthyretin-3',5'-dibromo-2',4,4',6-tetrahydroxyaurone complex.
Proc.Natl.Acad.Sci.USA, 89, 1992
1TRZ
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BU of 1trz by Molmil
CRYSTALLOGRAPHIC EVIDENCE FOR DUAL COORDINATION AROUND ZINC IN THE T3R3 HUMAN INSULIN HEXAMER
Descriptor: CHLORIDE ION, INSULIN, SODIUM ION, ...
Authors:Ciszak, E, Smith, G.D.
Deposit date:1993-11-19
Release date:1994-01-31
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic evidence for dual coordination around zinc in the T3R3 human insulin hexamer.
Biochemistry, 33, 1994
1BEN
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BU of 1ben by Molmil
INSULIN COMPLEXED WITH 4-HYDROXYBENZAMIDE
Descriptor: 4-HYDROXYBENZAMIDE, CHLORIDE ION, HUMAN INSULIN, ...
Authors:Smith, G.D, Ciszak, E, Pangborn, W.
Deposit date:1996-02-15
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A novel complex of a phenolic derivative with insulin: structural features related to the T-->R transition.
Protein Sci., 5, 1996
1TYL
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BU of 1tyl by Molmil
THE STRUCTURE OF A COMPLEX OF HEXAMERIC INSULIN AND 4'-HYDROXYACETANILIDE
Descriptor: CHLORIDE ION, INSULIN, N-(4-HYDROXYPHENYL)ACETAMIDE (TYLENOL), ...
Authors:Smith, G.D, Ciszak, E.
Deposit date:1994-06-21
Release date:1994-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of a complex of hexameric insulin and 4'-hydroxyacetanilide.
Proc.Natl.Acad.Sci.USA, 91, 1994
1TYM
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BU of 1tym by Molmil
THE STRUCTURE OF A COMPLEX OF HEXAMERIC INSULIN AND 4'-HYDROXYACETANILIDE
Descriptor: CHLORIDE ION, INSULIN, N-(4-HYDROXYPHENYL)ACETAMIDE (TYLENOL), ...
Authors:Smith, G.D, Ciszak, E.
Deposit date:1994-06-21
Release date:1994-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of a complex of hexameric insulin and 4'-hydroxyacetanilide.
Proc.Natl.Acad.Sci.USA, 91, 1994
1EV3
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BU of 1ev3 by Molmil
Structure of the rhombohedral form of the M-cresol/insulin R6 hexamer
Descriptor: CHLORIDE ION, INSULIN, M-CRESOL, ...
Authors:Smith, G.D, Ciszak, E, Magrum, L.A, Pangborn, W.A, Blessing, R.H.
Deposit date:2000-04-19
Release date:2000-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:R6 hexameric insulin complexed with m-cresol or resorcinol.
Acta Crystallogr.,Sect.D, 56, 2000
1EV6
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Structure of the monoclinic form of the M-cresol/insulin R6 hexamer
Descriptor: CHLORIDE ION, INSULIN, M-CRESOL, ...
Authors:Smith, G.D, Ciszak, E, Magrum, L.A, Pangborn, W.A, Blessing, R.H.
Deposit date:2000-04-19
Release date:2000-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:R6 Hexameric Insulin Complexed with m-Cresol or Resorcinol
Biochem.Biophys.Res.Commun., 56, 2000
1EVR
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BU of 1evr by Molmil
The structure of the resorcinol/insulin R6 hexamer
Descriptor: CHLORIDE ION, INSULIN, RESORCINOL, ...
Authors:Smith, G.D, Ciszak, E, Magrum, L.A, Pangborn, W.A, Blessing, R.H.
Deposit date:2000-04-20
Release date:2000-12-04
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:R6 hexameric insulin complexed with m-cresol or resorcinol.
Acta Crystallogr.,Sect.D, 56, 2000
1NI4
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BU of 1ni4 by Molmil
HUMAN PYRUVATE DEHYDROGENASE
Descriptor: MAGNESIUM ION, POTASSIUM ION, Pyruvate dehydrogenase E1 component: Alpha subunit, ...
Authors:Ciszak, E, Korotchkina, L.G, Dominiak, P.M, Sidhu, S, Patel, M.S.
Deposit date:2002-12-20
Release date:2003-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Basis for Flip-Flop Action of Thiamin Pyrophosphate-Dependent Enzymes Revealed by Human Pyruvate Dehydrogenase
J.Biol.Chem., 278, 2003
1CD2
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BU of 1cd2 by Molmil
LIGAND INDUCED CONFORMATIONAL CHANGES IN THE CRYSTAL STRUCTURES OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE COMPLEXES WITH FOLATE AND NADP+
Descriptor: DIHYDROFOLATE REDUCTASE, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Blakley, R.L, Gangjee, A.
Deposit date:1999-03-05
Release date:2000-03-06
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Ligand-induced conformational changes in the crystal structures of Pneumocystis carinii dihydrofolate reductase complexes with folate and NADP+.
Biochemistry, 38, 1999
1G7B
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BU of 1g7b by Molmil
1.3 A STRUCTURE OF T3R3 HUMAN INSULIN AT 100 K
Descriptor: ACETONE, CHLORIDE ION, GLYCEROL, ...
Authors:Smith, G.D, Pangborn, W.A, Blessing, R.H.
Deposit date:2000-11-09
Release date:2001-08-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Phase changes in T(3)R(3)(f) human insulin: temperature or pressure induced?
Acta Crystallogr.,Sect.D, 57, 2001
1G7A
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BU of 1g7a by Molmil
1.2 A structure of T3R3 human insulin at 100 K
Descriptor: ACETONE, CHLORIDE ION, GLYCEROL, ...
Authors:Smith, G.D, Pangborn, W.A, Blessing, R.H.
Deposit date:2000-11-09
Release date:2001-08-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Phase changes in T(3)R(3)(f) human insulin: temperature or pressure induced?
Acta Crystallogr.,Sect.D, 57, 2001
1TLM
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BU of 1tlm by Molmil
STRUCTURAL ASPECTS OF INOTROPIC BIPYRIDINE BINDING: CRYSTAL STRUCTURE DETERMINATION TO 1.9 ANGSTROMS OF THE HUMAN SERUM TRANSTHYRETIN-MILRINONE COMPLEX
Descriptor: MILRINONE, TRANSTHYRETIN
Authors:Wojtczak, A, Luft, J, Cody, V.
Deposit date:1992-12-22
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural aspects of inotropic bipyridine binding. Crystal structure determination to 1.9 A of the human serum transthyretin-milrinone complex.
J.Biol.Chem., 268, 1993
1ZEI
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BU of 1zei by Molmil
CROSS-LINKED B28 ASP INSULIN
Descriptor: CHLORIDE ION, INSULIN, M-CRESOL, ...
Authors:Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G.
Deposit date:1998-07-14
Release date:1999-02-16
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37, 1998
1ZEG
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BU of 1zeg by Molmil
STRUCTURE OF B28 ASP INSULIN IN COMPLEX WITH PHENOL
Descriptor: CHLORIDE ION, INSULIN, PHENOL, ...
Authors:Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G.
Deposit date:1998-05-01
Release date:1998-07-15
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37, 1998
1ZEH
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BU of 1zeh by Molmil
STRUCTURE OF INSULIN
Descriptor: CHLORIDE ION, INSULIN, M-CRESOL, ...
Authors:Whittingham, J.L, Edwards, E.J, Antson, A.A, Clarkson, J.M, Dodson, G.G.
Deposit date:1998-05-01
Release date:1998-12-09
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37, 1998
1HFP
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BU of 1hfp by Molmil
COMPARISON OF TERNARY CRYSTAL COMPLEXES OF HUMAN DIHYDROFOLATE REDUCTASE WITH NADPH AND A CLASSICAL ANTITUMOR FUROPYRIMDINE
Descriptor: DIHYDROFOLATE REDUCTASE, N-[4-[(2,4-DIAMINOFURO[2,3D]PYRIMIDIN-5-YL)METHYL]METHYLAMINO]-BENZOYL]-L-GLUTAMATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Blakley, R.L, Gangjee, A.
Deposit date:1997-11-04
Release date:1998-01-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Comparison of ternary crystal complexes of F31 variants of human dihydrofolate reductase with NADPH and a classical antitumor furopyrimidine.
Anti-Cancer Drug Des., 13, 1998
1HFQ
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BU of 1hfq by Molmil
COMPARISON OF TERNARY CRYSTAL COMPLEXES OF HUMAN DIHYDROFOLATE REDUCTASE WITH NADPH AND A CLASSICAL ANTITUMOR FUROPYRIMDINE
Descriptor: DIHYDROFOLATE REDUCTASE, N-[4-[(2,4-DIAMINOFURO[2,3D]PYRIMIDIN-5-YL)METHYL]METHYLAMINO]-BENZOYL]-L-GLUTAMATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Blakley, R.L, Gangjee, A.
Deposit date:1997-11-04
Release date:1998-01-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Comparison of ternary crystal complexes of F31 variants of human dihydrofolate reductase with NADPH and a classical antitumor furopyrimidine.
Anti-Cancer Drug Des., 13, 1998
1HFR
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BU of 1hfr by Molmil
COMPARISON OF TERNARY CRYSTAL COMPLEXES OF HUMAN DIHYDROFOLATE REDUCTASE WITH NADPH AND A CLASSICAL ANTITUMOR FUROPYRIMDINE
Descriptor: DIHYDROFOLATE REDUCTASE, N-[4-[(2,4-DIAMINOFURO[2,3D]PYRIMIDIN-5-YL)METHYL]METHYLAMINO]-BENZOYL]-L-GLUTAMATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Blakley, R.L, Gangjee, A.
Deposit date:1997-11-04
Release date:1998-01-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Comparison of ternary crystal complexes of F31 variants of human dihydrofolate reductase with NADPH and a classical antitumor furopyrimidine.
Anti-Cancer Drug Des., 13, 1998
1TYR
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BU of 1tyr by Molmil
TRANSTHYRETIN COMPLEX WITH RETINOIC ACID
Descriptor: (9cis)-retinoic acid, TRANSTHYRETIN
Authors:Zanotti, G, D'Acunto, M.R, Malpeli, G, Folli, C, Berni, R.
Deposit date:1995-05-12
Release date:1995-09-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the transthyretin--retinoic-acid complex
Eur.J.Biochem., 234, 1995
1OHJ
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BU of 1ohj by Molmil
HUMAN DIHYDROFOLATE REDUCTASE, MONOCLINIC (P21) CRYSTAL FORM
Descriptor: DIHYDROFOLATE REDUCTASE, N-(4-CARBOXY-4-{4-[(2,4-DIAMINO-PTERIDIN-6-YLMETHYL)-AMINO]-BENZOYLAMINO}-BUTYL)-PHTHALAMIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Cody, V, Galitsky, N, Luft, J.R, Pangborn, W.
Deposit date:1997-09-17
Release date:1998-04-29
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Comparison of two independent crystal structures of human dihydrofolate reductase ternary complexes reduced with nicotinamide adenine dinucleotide phosphate and the very tight-binding inhibitor PT523.
Biochemistry, 36, 1997
1OHK
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BU of 1ohk by Molmil
HUMAN DIHYDROFOLATE REDUCTASE, ORTHORHOMBIC (P21 21 21) CRYSTAL FORM
Descriptor: DIHYDROFOLATE REDUCTASE, N-(4-CARBOXY-4-{4-[(2,4-DIAMINO-PTERIDIN-6-YLMETHYL)-AMINO]-BENZOYLAMINO}-BUTYL)-PHTHALAMIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Cody, V, Galitsky, N, Luft, J.R, Pangborn, W.
Deposit date:1997-09-17
Release date:1998-05-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Comparison of two independent crystal structures of human dihydrofolate reductase ternary complexes reduced with nicotinamide adenine dinucleotide phosphate and the very tight-binding inhibitor PT523.
Biochemistry, 36, 1997
1RWE
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BU of 1rwe by Molmil
Enhancing the activity of insulin at receptor edge: crystal structure and photo-cross-linking of A8 analogues
Descriptor: CHLORIDE ION, Insulin, PHENOL, ...
Authors:Wan, Z, Xu, B, Chu, Y.C, Li, B, Nakagawa, S.H, Qu, Y, Hu, S.Q, Katsoyannis, P.G, Weiss, M.A.
Deposit date:2003-12-16
Release date:2005-02-15
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues.
Biochemistry, 43, 2004
2R35
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BU of 2r35 by Molmil
Crystal structure of RB human arg-insulin
Descriptor: Insulin, RUBIDIUM ION, SODIUM ION
Authors:Sreekanth, R, Pattabhi, V, Rajan, S.S.
Deposit date:2007-08-29
Release date:2008-09-02
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Metal induced structural changes observed in hexameric insulin
Int.J.Biol.Macromol., 44, 2009

 

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