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5L6S
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CRYSTAL STRUCTURE OF E. COLI ADP-GLUCOSE PYROPHOSPHORYLASE (AGPASE) IN COMPLEX WITH A POSITIVE ALLOSTERIC REGULATOR BETA-FRUCTOSE-1,6-DIPHOSPHATE (FBP) - AGPASE*FBP
Descriptor:Glucose-1-phosphate adenylyltransferase, SULFATE ION, BETA-FRUCTOSE-1,6-DIPHOSPHATE
Authors:Cifuente, J.O., Albesa-Jove, D., Comino, N., Madariaga-Marcos, J., Agirre, J., Lopez-Fernandez, S., Garcia-Alija, M., Guerin, M.E.
Deposit date:2016-05-31
Release date:2016-09-07
Last modified:2016-09-14
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structural Basis of Glycogen Biosynthesis Regulation in Bacteria.
Structure, 24, 2016
5L6V
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CRYSTAL STRUCTURE OF E. COLI ADP-GLUCOSE PYROPHOSPHORYLASE (AGPASE) IN COMPLEX WITH A NEGATIVE ALLOSTERIC REGULATOR ADENOSINE MONOPHOSPHATE (AMP) - AGPASE*AMP
Descriptor:Glucose-1-phosphate adenylyltransferase, ADENOSINE MONOPHOSPHATE, SUCROSE, ...
Authors:Cifuente, J.O., Albesa-Jove, D., Comino, N., Madariaga-Marcos, J., Agirre, J., Lopez-Fernandez, S., Garcia-Alija, M., Guerin, M.E.
Deposit date:2016-05-31
Release date:2016-09-07
Last modified:2016-09-14
Method:X-RAY DIFFRACTION (2.667 Å)
Cite:Structural Basis of Glycogen Biosynthesis Regulation in Bacteria.
Structure, 24, 2016
5MNI
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ESCHERICHIA COLI AGPASE MUTANT R130A APO FORM
Descriptor:Glucose-1-phosphate adenylyltransferase
Authors:Cifuente, J.O., Comino, N., Marina, A., Orrantia, A., Eguskiza, A., Guerin, M.E.
Deposit date:2016-12-13
Release date:2017-03-01
Last modified:2017-04-26
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Mechanistic insights into the allosteric regulation of bacterial ADP-glucose pyrophosphorylases.
J. Biol. Chem., 292, 2017
3IYP
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THE INTERACTION OF DECAY-ACCELERATING FACTOR WITH ECHOVIRUS 7
Descriptor:Capsid protein, Polyprotein, Complement decay-accelerating factor, ...
Authors:Plevka, P., Hafenstein, S., Zhang, Y., Harris, K.G., Cifuente, J.O., Bowman, V.D., Chipman, P.R., Lin, F., Medof, D.E., Bator, C.M., Rossmann, M.G.
Deposit date:2010-04-07
Release date:2010-11-24
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Interaction of decay-accelerating factor with echovirus 7.
J.Virol., 84, 2010
3J3Z
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STRUCTURE OF MA28-7 NEUTRALIZING ANTIBODY FAB FRAGMENT FROM ELECTRON CRYO-MICROSCOPY OF ENTEROVIRUS 71 COMPLEXED WITH A FAB FRAGMENT
Descriptor:MA28-7 neutralizing antibody light chain, MA28-7 neutralizing antibody heavy chain
Authors:Lee, H., Cifuente, J.O., Ashley, R.E., Conway, J.F., Makhov, A.M., Tano, Y., Shimizu, H., Nishimura, Y., Hafenstein, S.
Deposit date:2013-05-21
Release date:2013-08-28
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (23.4 Å)
Cite:A strain-specific epitope of enterovirus 71 identified by cryo-electron microscopy of the complex with fab from neutralizing antibody.
J.Virol., 87, 2013
3J91
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CRYO-ELECTRON MICROSCOPY OF ENTEROVIRUS 71 (EV71) PROCAPSID IN COMPLEX WITH FAB FRAGMENTS OF NEUTRALIZING ANTIBODY 22A12
Descriptor:VP0, VP1, VP3
Authors:Shingler, K.L., Cifuente, J.O., Ashley, R.E., Makhov, A.M., Conway, J.F., Hafenstein, S.
Deposit date:2014-11-24
Release date:2014-12-10
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (8.8 Å)
Cite:The enterovirus 71 procapsid binds neutralizing antibodies and rescues virus infection in vitro.
J.Virol., 89, 2015
3J93
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FITTING OF FAB INTO THE CRYOEM DENSITY MAP OF EV71 PROCAPSID IN COMPLEX WITH FAB22A12
Descriptor:neutralizing antibody 22A12, light chain, heavy chain
Authors:Shingler, K.L., Cifuente, J.O., Ashley, R.E., Makhov, A.M., Conway, J.F., Hafenstein, S.
Deposit date:2014-12-02
Release date:2014-12-24
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (8.8 Å)
Cite:The enterovirus 71 procapsid binds neutralizing antibodies and rescues virus infection in vitro.
J.Virol., 89, 2015
4Y6N
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CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MN2+, URIDINE-DIPHOSPHATE-GLUCOSE (UDP-GLC) AND PHOSPHOGLYCERIC ACID (PGA) - GPGS MN2+ UDP-GLC PGA-1
Descriptor:Glucosyl-3-phosphoglycerate synthase, MANGANESE (II) ION, 3-PHOSPHOGLYCERIC ACID, ...
Authors:Albesa-Jove, D., Rodrigo-Unzueta, A., Cifuente, J.O., Urresti, S., Comino, N., Sancho-Vaello, E., Guerin, M.E.
Deposit date:2015-02-13
Release date:2015-07-15
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.348 Å)
Cite:A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase.
Angew.Chem.Int.Ed.Engl., 54, 2015
4Y6U
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MYCOBACTERIAL PROTEIN
Descriptor:Glucosyl-3-phosphoglycerate synthase, MANGANESE (II) ION, CHLORIDE ION, ...
Authors:Albesa-Jove, D., Rodrigo-Unzueta, A., Cifuente, J.O., Urresti, S., Comino, N., Sancho-Vaello, E., Guerin, M.E.
Deposit date:2015-02-13
Release date:2015-07-15
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.271 Å)
Cite:A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase.
Angew.Chem.Int.Ed.Engl., 54, 2015
4Y7F
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CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MN2+, URIDINE-DIPHOSPHATE-GLUCOSE (UDP-GLC) AND 3-(PHOSPHONOOXY)PROPANOIC ACID (PPA) - GPGS MN2+ UDP-GLC PPA
Descriptor:Glucosyl-3-phosphoglycerate synthase, MANGANESE (II) ION, 3-(phosphonooxy)propanoic acid, ...
Authors:Albesa-Jove, D., Rodrigo-Unzueta, A., Cifuente, J.O., Urresti, S., Comino, N., Sancho-Vaello, E., Guerin, M.E.
Deposit date:2015-02-14
Release date:2015-07-15
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (3.231 Å)
Cite:A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase.
Angew.Chem.Int.Ed.Engl., 54, 2015
4Y7G
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CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MN2+, URIDINE-DIPHOSPHATE-GLUCOSE (UDP-GLC) AND GLYCEROL 3-PHOSPHATE (G3P) - GPGS MN2+ UDP-GLC G3P
Descriptor:Glucosyl-3-phosphoglycerate synthase, MANGANESE (II) ION, SN-GLYCEROL-3-PHOSPHATE, ...
Authors:Albesa-Jove, D., Rodrigo-Unzueta, A., Cifuente, J.O., Urresti, S., Comino, N., Sancho-Vaello, E., Guerin, M.E.
Deposit date:2015-02-14
Release date:2015-07-15
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase.
Angew.Chem.Int.Ed.Engl., 54, 2015
4Y9X
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CRYSTAL STRUCTURE OF GLUCOSYL-3-PHOSPHOGLYCERATE SYNTHASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MN2+, URIDINE-DIPHOSPHATE-GLUCOSE (UDP-GLC) AND PHOSPHOGLYCERIC ACID (PGA) - GPGS MN2+ UDP-GLC PGA-3
Descriptor:Glucosyl-3-phosphoglycerate synthase, MANGANESE (II) ION, CHLORIDE ION, ...
Authors:Albesa-Jove, D., Rodrigo-Unzueta, A., Cifuente, J.O., Urresti, S., Comino, N., Sancho-Vaello, E., Guerin, M.E.
Deposit date:2015-02-17
Release date:2015-07-15
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.637 Å)
Cite:A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase.
Angew.Chem.Int.Ed.Engl., 54, 2015
5F2T
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CRYSTAL STRUCTURE OF MEMBRANE ASSOCIATED PATA FROM MYCOBACTERIUM SMEGMATIS IN COMPLEX WITH PALMITATE - C 2 SPACE GROUP
Descriptor:Phosphatidylinositol mannoside acyltransferase, PALMITIC ACID, MAGNESIUM ION
Authors:Albesa-Jove, D., Svetlikova, Z., Carreras-Gonzalez, A., Tersa, M., Sancho-Vaello, E., Cifuente, J.O., Mikusova, K., Guerin, M.E.
Deposit date:2015-12-02
Release date:2016-03-09
Last modified:2016-03-23
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA.
Nat Commun, 7, 2016
5F2Z
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CRYSTAL STRUCTURE OF MEMBRANE ASSOCIATED PATA FROM MYCOBACTERIUM SMEGMATIS IN COMPLEX WITH PALMITATE - P21 SPACE GROUP
Descriptor:Phosphatidylinositol mannoside acyltransferase, PALMITIC ACID
Authors:Albesa-Jove, D., Svetlikova, Z., Carreras-Gonzalez, A., Tersa, M., Sancho-Vaello, E., Cifuente, J.O., Mikusova, K., Guerin, M.E.
Deposit date:2015-12-02
Release date:2016-03-09
Last modified:2016-03-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA.
Nat Commun, 7, 2016
5F31
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CRYSTAL STRUCTURE OF MEMBRANE ASSOCIATED PATA FROM MYCOBACTERIUM SMEGMATIS IN COMPLEX WITH PALMITATE - P 42 21 2 SPACE GROUP
Descriptor:Phosphatidylinositol mannoside acyltransferase, PALMITIC ACID, ETHANOL, ...
Authors:Albesa-Jove, D., Svetlikova, Z., Carreras-Gonzalez, A., Tersa, M., Sancho-Vaello, E., Cifuente, J.O., Mikusova, K., Guerin, M.E.
Deposit date:2015-12-02
Release date:2016-03-09
Last modified:2016-03-23
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA.
Nat Commun, 7, 2016
5F34
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CRYSTAL STRUCTURE OF MEMBRANE ASSOCIATED PATA FROM MYCOBACTERIUM SMEGMATIS IN COMPLEX WITH S-HEXADECYL COENZYME A - P21 SPACE GROUP
Descriptor:Phosphatidylinositol mannoside acyltransferase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{S})-4-[[3-(2-hexadecylsulfanylethylamino)-3-oxidanylidene-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate
Authors:Albesa-Jove, D., Svetlikova, Z., Carreras-Gonzalez, A., Tersa, M., Sancho-Vaello, E., Cifuente, J.O., Mikusova, K., Guerin, M.E.
Deposit date:2015-12-02
Release date:2016-03-09
Last modified:2016-03-23
Method:X-RAY DIFFRACTION (3.281 Å)
Cite:Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA.
Nat Commun, 7, 2016
4GMP
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CRYSTAL STRUCTURE OF ENTEROVIRUS 71 STRAIN 1095 PROCAPSID
Descriptor:capsid protein VP0, capsid protein VP1, capsid protein VP3
Authors:Yoder, J.D., Hafenstein, S.
Deposit date:2012-08-16
Release date:2013-05-15
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structures of the procapsid and mature virion of enterovirus 71 strain 1095.
J.Virol., 87, 2013
2X5I
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CRYSTAL STRUCTURE ECHOVIRUS 7
Descriptor:VP1, VP2, VP3, ...
Authors:Plevka, P., Hafenstein, S., Zhang, Y., Bowman, V.D., Chipman, P.R., Bator, C.M., Rossmann, M.G.
Deposit date:2010-02-08
Release date:2010-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Interaction of Decay-Accelerating Factor with Echovirus 7.
J.Virol., 84, 2010
3J24
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CRYOEM RECONSTRUCTION OF COMPLEMENT DECAY-ACCELERATING FACTOR
Descriptor:Complement decay-accelerating factor
Authors:Yoder, J.D., Hafenstein, S.H.
Deposit date:2012-08-17
Release date:2012-09-26
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9 Å)
Cite:The Crystal Structure of a Coxsackievirus B3-RD Variant and a Refined 9-Angstrom Cryo-Electron Microscopy Reconstruction of the Virus Complexed with Decay-Accelerating Factor (DAF) Provide a New Footprint of DAF on the Virus Surface.
J.Virol., 86, 2012
4GB3
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HUMAN COXSACKIEVIRUS B3 STRAIN RD COAT PROTEIN
Descriptor:coat protein 1, coat protein 2, coat protein 3, ...
Authors:Yoder, J.D., Hafenstein, S.
Deposit date:2012-07-26
Release date:2012-09-26
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:The Crystal Structure of a Coxsackievirus B3-RD Variant and a Refined 9-Angstrom Cryo-Electron Microscopy Reconstruction of the Virus Complexed with Decay-Accelerating Factor (DAF) Provide a New Footprint of DAF on the Virus Surface.
J.Virol., 86, 2012