Author results

1P9M
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CRYSTAL STRUCTURE OF THE HEXAMERIC HUMAN IL-6/IL-6 ALPHA RECEPTOR/GP130 COMPLEX
Descriptor:Interleukin-6 receptor beta chain, Interleukin-6, Interleukin-6 receptor alpha chain
Authors:Boulanger, M.J., Chow, D.C., Brevnova, E.E., Garcia, K.C.
Deposit date:2003-05-12
Release date:2003-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Hexameric Structure and Assembly of the Interleukin-6/IL-6 alpha-Receptor/gp130 Complex
Science, 300, 2003
1R5V
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EVIDENCE THAT STRUCTURAL REARRANGEMENTS AND/OR FLEXIBILITY DURING TCR BINDING CAN CONTRIBUTE TO T-CELL ACTIVATION
Descriptor:H-2 class II histocompatibility antigen, E-K alpha chain, artificial peptide, ...
Authors:Krogsgaard, M., Prado, N., Adams, E.J., He, X.L., Chow, D.C., Wilson, D.B., Garcia, K.C., Davis, M.M.
Deposit date:2003-10-13
Release date:2004-02-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation.
Mol.Cell, 12, 2003
1R5W
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EVIDENCE THAT STRUCTURAL REARRANGEMENTS AND/OR FLEXIBILITY DURING TCR BINDING CAN CONTRIBUTE TO T-CELL ACTIVATION
Descriptor:H-2 class II histocompatibility antigen, E-K alpha chain, MHC H2-IE-beta, ...
Authors:Krogsgaard, M., Prado, N., Adams, E., He, X., Chow, D.C., Wilson, D.B., Garcia, K.C., Davis, M.M.
Deposit date:2003-10-13
Release date:2004-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation
Mol.Cell, 12, 2003
3QHY
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STRUCTURAL, THERMODYNAMIC AND KINETIC ANALYSIS OF THE PICOMOLAR BINDING AFFINITY INTERACTION OF THE BETA-LACTAMASE INHIBITOR PROTEIN-II (BLIP-II) WITH CLASS A BETA-LACTAMASES
Descriptor:Beta-lactamase, Beta-lactamase inhibitory protein II
Authors:Brown, N.G., Chow, D.C., Sankaran, B., Zwart, P., Prasad, B.V.V., Palzkill, T., Berkeley Structural Genomics Center (BSGC)
Deposit date:2011-01-26
Release date:2011-07-20
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Analysis of the binding forces driving the tight interactions between beta-lactamase inhibitory protein-II (BLIP-II) and class A beta-lactamases.
J.Biol.Chem., 286, 2011
3QI0
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STRUCTURAL, THERMODYNAMIC AND KINETIC ANALYSIS OF THE PICOMOLAR BINDING AFFINITY INTERACTION OF THE BETA-LACTAMASE INHIBITOR PROTEIN-II (BLIP-II) WITH CLASS A BETA-LACTAMASES
Descriptor:Beta-lactamase inhibitory protein II, SULFATE ION
Authors:Brown, N.G., Chow, D.C., Sankaran, B., Zwart, P., Prasad, B.V.V., Palzkill, T.
Deposit date:2011-01-26
Release date:2011-07-20
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Analysis of the binding forces driving the tight interactions between beta-lactamase inhibitory protein-II (BLIP-II) and class A beta-lactamases.
J.Biol.Chem., 286, 2011
1JDN
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CRYSTAL STRUCTURE OF HORMONE RECEPTOR
Descriptor:ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, BETA-D-MANNOSE, ...
Authors:He, X.-L., Chow, D.-C., Martick, M.M., Garcia, K.C.
Deposit date:2001-06-14
Release date:2001-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone.
Science, 293, 2001
1JDP
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CRYSTAL STRUCTURE OF HORMONE/RECEPTOR COMPLEX
Descriptor:ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR, C-TYPE NATRIURETIC PEPTIDE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:He, X.-L., Chow, D.-C., Martick, M.M., Garcia, K.C.
Deposit date:2001-06-14
Release date:2001-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone.
Science, 293, 2001
3C7U
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STRUCTURAL INSIGHT INTO THE KINETICS AND CP OF INTERACTIONS BETWEEN TEM-1-LACTAMASE AND BLIP
Descriptor:Beta-lactamase, Beta-lactamase inhibitory protein
Authors:Wang, J., Chow, D.-C.
Deposit date:2008-02-08
Release date:2008-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural insight into the kinetics and DeltaCp of interactions between TEM-1 beta-lactamase and beta-lactamase inhibitory protein (BLIP)
J.Biol.Chem., 284, 2009
3C7V
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STRUCTURAL INSIGHT INTO THE KINETICS AND DELTA-CP OF INTERACTIONS BETWEEN TEM-1 BETA-LACTAMASE AND BLIP
Descriptor:Beta-lactamase, Beta-lactamase inhibitory protein
Authors:Wang, J., Chow, D.-C.
Deposit date:2008-02-08
Release date:2008-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural insight into the kinetics and DeltaCp of interactions between TEM-1 beta-lactamase and beta-lactamase inhibitory protein (BLIP)
J.Biol.Chem., 284, 2009
4RVA
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A TRIPLE MUTANT IN THE OMEGA-LOOP OF TEM-1 BETA-LACTAMASE CHANGES THE SUBSTRATE PROFILE VIA A LARGE CONFORMATIONAL CHANGE AND AN ALTERED GENERAL BASE FOR DEACYLATION
Descriptor:Beta-lactamase TEM, BICARBONATE ION
Authors:Stojanoski, V., Chow, D.-C., Hu, L., Sankaran, B., Gilbert, H., Prasad, B.V.V., Palzkill, T.
Deposit date:2014-11-25
Release date:2015-03-04
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (1.4397 Å)
Cite:A Triple Mutant in the Omega-loop of TEM-1 beta-Lactamase Changes the Substrate Profile via a Large Conformational Change and an Altered General Base for Catalysis.
J.Biol.Chem., 290, 2015
4RX2
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A TRIPLE MUTANT IN THE OMEGA-LOOP OF TEM-1 BETA-LACTAMASE CHANGES THE SUBSTRATE PROFILE VIA A LARGE CONFORMATIONAL CHANGE AND AN ALTERED GENERAL BASE FOR CATALYSIS
Descriptor:Beta-lactamase TEM, SULFATE ION
Authors:Stojanoski, V., Chow, D., Hu, L., Sankaran, B., Gilbert, H., Prasad, B.V.V., Palzkill, T.
Deposit date:2014-12-08
Release date:2015-03-04
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (2.315 Å)
Cite:A Triple Mutant in the Omega-loop of TEM-1 beta-Lactamase Changes the Substrate Profile via a Large Conformational Change and an Altered General Base for Catalysis.
J.Biol.Chem., 290, 2015
4RX3
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A TRIPLE MUTANT IN THE OMEGA-LOOP OF TEM-1 BETA-LACTAMASE CHANGES THE SUBSTRATE PROFILE VIA A LARGE CONFORMATIONAL CHANGE AND AN ALTERED GENERAL BASE FOR CATALYSIS
Descriptor:Beta-lactamase TEM, CITRATE ANION
Authors:Stojanoski, V., Chow, D., Hu, L., Sankaran, B., Gilbert, H., Prasad, B.V.V., Palzkill, T.
Deposit date:2014-12-08
Release date:2015-03-04
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:A Triple Mutant in the Omega-loop of TEM-1 beta-Lactamase Changes the Substrate Profile via a Large Conformational Change and an Altered General Base for Catalysis.
J.Biol.Chem., 290, 2015
2LJL
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NMR STRUCTURE OF HSP12 IN THE PRESENCE OF DPC
Descriptor:12 kDa heat shock protein
Authors:Singarapu, K., Markley, J., Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2011-09-20
Release date:2011-10-12
Last modified:2012-10-10
Method:SOLUTION NMR
Cite:Structural characterization of Hsp12, the heat shock protein from Saccharomyces cerevisiae, in aqueous solution where it is intrinsically disordered and in detergent micelles where it is locally alpha-helical.
J.Biol.Chem., 286, 2011
3OCP
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CRYSTAL STRUCTURE OF CAMP BOUND CGMP-DEPENDENT PROTEIN KINASE(92-227)
Descriptor:PRKG1 protein, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
Authors:Kim, J.J., Huang, G., Kwon, T.K., Zwart, P., Headd, J., Kim, C.
Deposit date:2010-08-10
Release date:2011-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Co-Crystal Structures of PKG Ibeta (92-227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding
Plos One, 6, 2011
3OD0
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CRYSTAL STRUCTURE OF CGMP BOUND CGMP-DEPENDENT PROTEIN KINASE(92-227)
Descriptor:PRKG1 protein, CYCLIC GUANOSINE MONOPHOSPHATE
Authors:Kim, J.J., Huang, G., Kwon, T.K., Zwart, P., Headd, J., Kim, C.
Deposit date:2010-08-10
Release date:2011-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Co-Crystal Structures of PKG Ibeta (92-227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding
Plos One, 6, 2011
3OGJ
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CRYSTAL STRUCTURE OF PARTIAL APO (92-227) OF CGMP-DEPENDENT PROTEIN KINASE
Descriptor:PRKG1 protein, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, PHOSPHATE ION
Authors:Kim, J.J., Huang, G., Kwon, T.K., Zwart, P., Headd, J., Kim, C.
Deposit date:2010-08-16
Release date:2011-05-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.751 Å)
Cite:Co-Crystal Structures of PKG Ibeta (92-227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding
Plos One, 6, 2011
4G0A
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CRYSTALLOGRAPHIC ANALYSIS OF ROTAVIRUS NSP2-RNA COMPLEX REVEALS SPECIFIC RECOGNITION OF 5'-GG SEQUENCE FOR RTPASE ACTIVITY
Descriptor:Non-structural protein 2, RNA (5'-R(P*GP*GP*U)-3'), CHLORIDE ION, ...
Authors:Hu, L., Prasad, B.V.V.
Deposit date:2012-07-09
Release date:2012-08-22
Last modified:2012-09-26
Method:X-RAY DIFFRACTION (2.0995 Å)
Cite:Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity.
J.Virol., 86, 2012
4G0J
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CRYSTALLOGRAPHIC ANALYSIS OF ROTAVIRUS NSP2-RNA COMPLEX REVEALS SPECIFIC RECOGNITION OF 5'-GG SEQUENCE FOR RTPASE ACTIVITY
Descriptor:Non-structural protein 2
Authors:Hu, L., Prasad, B.V.V.
Deposit date:2012-07-09
Release date:2012-08-22
Last modified:2012-09-26
Method:X-RAY DIFFRACTION (3.398 Å)
Cite:Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity.
J.Virol., 86, 2012
4S2L
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CRYSTAL STRUCTURE OF OXA-163 BETA-LACTAMASE
Descriptor:Beta-lactamase, SODIUM ION
Authors:Stojanoski, V., Liya, H., Palzkill, T.G., Prasad, B., Sankaran, B.
Deposit date:2015-01-21
Release date:2015-07-22
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structural Basis for Different Substrate Profiles of Two Closely Related Class D beta-Lactamases and Their Inhibition by Halogens.
Biochemistry, 54, 2015
4S2M
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CRYSTAL STRUCTURE OF OXA-163 COMPLEXED WITH IODIDE IN THE ACTIVE SITE
Descriptor:Beta-lactamase, IODIDE ION
Authors:Stojanoski, V., Hu, L., Palzkill, T.G., Prasad, B.
Deposit date:2015-01-21
Release date:2015-07-22
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structural Basis for Different Substrate Profiles of Two Closely Related Class D beta-Lactamases and Their Inhibition by Halogens.
Biochemistry, 54, 2015