Author results

3W5K
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CRYSTAL STRUCTURE OF SNAIL1 AND IMPORTIN BETA COMPLEX
分子名称:Importin subunit beta-1, Zinc finger protein SNAI1, ZINC ION
著者Choi, S., Yamashita, E., Yasuhara, N., Song, J., Son, S.Y., Won, Y.H., Shin, Y.S., Sekimoto, T., Park, I.Y., Yoneda, Y., Lee, S.J.
登録日2013-01-30
公開日2014-03-05
最終更新日2014-05-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for the selective nuclear import of the C2H2 zinc-finger protein Snail by importin beta.
Acta Crystallogr.,Sect.D, 70, 2014
3OYY
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STRUCTURE OF PSEUDOMONAS AERUGINOSA ELONGATION FACTOR P
分子名称:Elongation factor P, PHOSPHATE ION
著者Choe, J., Choi, S.
登録日2010-09-24
公開日2011-03-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of elongation factor P from Pseudomonas aeruginosa at 1.75 A resolution
Proteins: Struct.,Funct.,Genet., 2011
1QXH
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI THIOL PEROXIDASE IN THE OXIDIZED STATE
分子名称:Thiol peroxidase
著者Choi, J., Choi, S., Choi, J., Shin, W.
登録日2003-09-06
公開日2004-01-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Escherichia coli thiol peroxidase in the oxidized state: insights into intramolecular disulfide formation and substrate binding in atypical 2-Cys peroxiredoxins
J.Biol.Chem., 278, 2003
2A4V
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CRYSTAL STRUCTURE OF A TRUNCATED MUTANT OF YEAST NUCLEAR THIOL PEROXIDASE
分子名称:Peroxiredoxin DOT5
著者Choi, J., Choi, S., Chon, J.-K., Choi, J., Cha, M.-K., Kim, I.-H., Shin, W.
登録日2005-06-29
公開日2006-03-14
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the C107S/C112S mutant of yeast nuclear 2-Cys peroxiredoxin
Proteins, 61, 2005
3NJ4
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FLUORO-NEPLANOCIN A IN HUMAN S-ADENOSYLHOMOCYSTEINE HYDROLASE
分子名称:Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, (4S,5S)-4-(6-amino-9H-purin-9-yl)-3-fluoro-5-hydroxy-2-(hydroxymethyl)cyclopent-2-en-1-one
著者Jeong, L.S., Lee, K.M., Hwang, K.Y., Choi, S., Heo, Y.S.
登録日2010-06-17
公開日2011-05-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献X-ray crystal structure and binding mode analysis of human S-adenosylhomocysteine hydrolase complexed with novel mechanism-based inhibitors, haloneplanocin A analogues.
J.Med.Chem., 54, 2011
3E4A
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HUMAN IDE-INHIBITOR COMPLEX AT 2.6 ANGSTROM RESOLUTION
分子名称:Insulin-degrading enzyme, HYDROXAMATE PEPTIDE II1, ZINC ION, ...
著者Malito, E., Leissring, M.A., Choi, S., Cuny, G.D., Tang, W.J.
登録日2008-08-11
公開日2009-05-19
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Designed inhibitors of insulin-degrading enzyme regulate the catabolism and activity of insulin.
Plos One, 5, 2010
3TVZ
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STRUCTURE OF BACILLUS SUBTILIS HMOB
分子名称:Putative uncharacterized protein yhgC
著者Choe, J., Choi, S., Park, S.
登録日2011-09-21
公開日2012-07-11
最終更新日2019-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Bacillus subtilis HmoB is a heme oxygenase with a novel structure.
Bmb Rep, 45, 2012
3WVZ
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CRYSTAL STRUCTURE OF HIKESHI, A NEW NUCLEAR TRANSPORT RECEPTOR OF HSP70
分子名称:Protein Hikeshi
著者Song, J., Kose, S., Watanabe, A., Son, S.Y., Choi, S., Hong, R.H., Yamashita, E., Park, I.Y., Imamoto, N., Lee, S.J.
登録日2014-06-12
公開日2015-03-25
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structural and functional analysis of Hikeshi, a new nuclear transport receptor of Hsp70s
Acta Crystallogr.,Sect.D, 71, 2015
3WW0
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CRYSTAL STRUCTURE OF F97A MUTANT, A NEW NUCLEAR TRANSPORT RECEPTOR OF HSP70
分子名称:Protein Hikeshi
著者Song, J., Kose, S., Watanabe, A., Son, S.Y., Choi, S., Hong, R.H., Yamashita, E., Park, I.Y., Imamoto, N., Lee, S.J.
登録日2014-06-12
公開日2015-03-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional analysis of Hikeshi, a new nuclear transport receptor of Hsp70s
Acta Crystallogr.,Sect.D, 71, 2015
4KY2
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TRANSTHYRETIN IN COMPLEX WITH THE FLUORESCENT FOLDING SENSOR (E)-7-HYDROXY-3-(4-HYDROXY-3,5-DIMETHYLSTYRYL)-4-METHYL-2H-CHROMEN-2-ONE
分子名称:Transthyretin, 7-hydroxy-3-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]-4-methyl-2H-chromen-2-one
著者Connelly, S., Wilson, I.A., Choi, S.
登録日2013-05-28
公開日2013-08-28
最終更新日2014-02-05
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Bifunctional coumarin derivatives that inhibit transthyretin amyloidogenesis and serve as fluorescent transthyretin folding sensors.
Chem.Commun.(Camb.), 49, 2013
5TZL
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STRUCTURE OF TRANSTHYRETIN IN COMPLEX WITH THE KINETIC STABILIZER 201
分子名称:Transthyretin, 4-(7-chloro-1,3-benzoxazol-2-yl)-2,6-diiodophenol
著者Connelly, S., Mortenson, D.E., Choi, S., Wilson, I.A., Powers, E.T., Kelly, J.W., Johnson, S.M.
登録日2016-11-21
公開日2017-06-28
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
6II0
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CRYSTAL STRUCTURE OF THE MAKES CATERPILLARS FLOPPY (MCF)-LIKE EFFECTOR OF VIBRIO VULNIFICUS MO6-24/O
分子名称:Putative RTX-toxin, GLYCEROL
著者Lee, Y., Kim, B.S., Choi, S., Lee, E.Y., Park, S., Hwang, J., Kwon, Y., Hyun, J., Lee, C., Eom, S.H., Kim, M.H.
登録日2018-10-03
公開日2019-08-07
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Crystal Structure of Pathogenic Bacterial Toxin A
To Be Published
6II2
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CRYSTAL STRUCTURE OF ALPHA-BETA HYDROLASE (ABH) AND MAKES CATERPILLARS FLOPPY (MCF)-LIKE EFFECTORS OF VIBRIO VULNIFICUS MO6-24/O
分子名称:Putative RTX-toxin
著者Lee, Y., Kim, B.S., Choi, S., Lee, E.Y., Park, S., Hwang, J., Kwon, Y., Hyung, J., Lee, C., Eom, S.H., Kim, M.H.
登録日2018-10-03
公開日2019-08-07
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal Structure of Pathogenic Bacterial Toxin AB
To Be Published
6II6
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CRYSTAL STRUCTURE OF THE MAKES CATERPILLARS FLOPPY (MCF)-LIKE EFFECTOR OF VIBRIO VULNIFICUS MO6-24/O IN COMPLEX WITH A HUMAN ADP-RIBOSYLATION FACTOR 3 (ARF3)
分子名称:Putative RTX-toxin, ADP-ribosylation factor 3, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Lee, Y., Kim, B.S., Choi, S., Lee, E.Y., Park, S., Hwang, J., Kwon, Y., Hyun, J., Lee, C., Eom, S.H., Kim, M.H.
登録日2018-10-03
公開日2019-08-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Pathogenic Bacterial Toxin A with a Host Protein
To Be Published
3B1F
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CRYSTAL STRUCTURE OF PREPHENATE DEHYDROGENASE FROM STREPTOCOCCUS MUTANS
分子名称:Putative prephenate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Ku, H.K., Do, N.H., Song, J.S., Choi, S., Shin, M.H., Kim, K.J., Lee, S.J.
登録日2011-07-02
公開日2011-10-26
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of prephenate dehydrogenase from Streptococcus mutans.
Int.J.Biol.Macromol., 49, 2011
4BGG
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CRYSTAL STRUCTURE OF THE ACVR1 KINASE IN COMPLEX WITH LDN-213844
分子名称:ACTIVIN RECEPTOR TYPE-1, 1-{4-[5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl}piperazine, CITRATE ANION, ...
著者Sanvitale, C., Canning, P., Cooper, C., Wang, Y., Mohedas, A.H., Choi, S., Yu, P.B., Cuny, G.D., Nowak, R., Coutandin, D., Vollmar, M., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A., Structural Genomics Consortium (SGC)
登録日2013-03-26
公開日2013-04-10
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structure-Activity Relationship of 3,5-Diaryl-2-Aminopyridine Alk2 Inhibitors Reveals Unaltered Binding Affinity for Fibrodysplasia Ossificans Progressiva Causing Mutants.
J.Med.Chem., 57, 2014
4LUB
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X-RAY STRUCTURE OF PREPHENATE DEHYDRATASE FROM STREPTOCOCCUS MUTANS
分子名称:Putative prephenate dehydratase
著者Shin, H.H., Ku, H.K., Song, J.S., Choi, S., Son, S.Y.
登録日2013-07-25
公開日2014-02-12
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray structure of prephenate dehydratase from Streptococcus mutans
TO BE PUBLISHED
3HJ0
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TRANSTHYRETIN IN COMPLEX WITH A COVALENT SMALL MOLECULE KINETIC STABILIZER
分子名称:Transthyretin, 4-fluorophenyl 3-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzoate
著者Connelly, S., Wilson, I.A., Kelly, J.W.
登録日2009-05-20
公開日2009-12-22
最終更新日2014-11-19
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma.
Nat.Chem.Biol., 6, 2010
3IMR
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TRANSTHYRETIN IN COMPLEX WITH (E)-2,6-DIBROMO-4-(2,6-DICHLOROSTYRYL)PHENOL
分子名称:Transthyretin, 2,6-dibromo-4-[(E)-2-(2,6-dichlorophenyl)ethenyl]phenol
著者Connelly, S., Wilson, I.A.
登録日2009-08-11
公開日2010-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
3IMS
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TRANSTHYRETIN IN COMPLEX WITH 2,6-DIBROMO-4-(2,6-DICHLOROPHENETHYL)PHENOL
分子名称:Transthyretin, 2,6-dibromo-4-[2-(2,6-dichlorophenyl)ethyl]phenol
著者Connelly, S., Wilson, I.A.
登録日2009-08-11
公開日2010-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
3IMT
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TRANSTHYRETIN IN COMPLEX WITH (E)-4-(4-AMINOSTYRYL)-2,6-DIBROMOPHENOL
分子名称:Transthyretin, 4-[(E)-2-(4-aminophenyl)ethenyl]-2,6-dibromophenol
著者Connelly, S., Wilson, I.
登録日2009-08-11
公開日2010-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
3IMU
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TRANSTHYRETIN IN COMPLEX WITH (E)-4-(3-AMINOSTYRYL)-2,6-DIBROMOANILINE
分子名称:Transthyretin, 4-[(E)-2-(3-aminophenyl)ethenyl]-2,6-dibromoaniline
著者Connelly, S., Wilson, I.A.
登録日2009-08-11
公開日2010-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
3IMV
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TRANSTHYRETIN IN COMPLEX WITH (E)-4-(4-AMINOSTYRYL)-2,6-DIBROMOANILINE
分子名称:Transthyretin, 4-[(E)-2-(4-aminophenyl)ethenyl]-2,6-dibromoaniline
著者Connelly, S., Wilson, I.A.
登録日2009-08-11
公開日2010-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
3IMW
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TRANSTHYRETIN IN COMPLEX WITH (E)-2,6-DIBROMO-4-(2,6-DIMETHOXYSTYRYL)ANILINE
分子名称:Transthyretin, 2,6-dibromo-4-[(E)-2-(2,6-dimethoxyphenyl)ethenyl]aniline
著者Connelly, S., Wilson, I.A.
登録日2009-08-11
公開日2010-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
4ZJ1
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CRYSTAL STRUCTURE OF P-ACRYLAMIDO-PHENYLALANINE MODIFIED TEM1 BETA-LACTAMASE FROM ESCHERICHIA COLI : V216ACRF MUTANT
分子名称:Beta-lactamase TEM, GLYCEROL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Xiao, H., Nasertorabi, F., Choi, S., Han, G.W., Reed, S.A., Stevens, R.C., Schultz, P.G.
登録日2015-04-28
公開日2015-05-20
最終更新日2016-07-20
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Exploring the potential impact of an expanded genetic code on protein function.
Proc.Natl.Acad.Sci.USA, 112, 2015
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