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4E18
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BU of 4e18 by Molmil
Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin
Descriptor: Catenin alpha-1, Vinculin
Authors:Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I.
Deposit date:2012-03-05
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.403 Å)
Cite:Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin
To be Published
4E17
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BU of 4e17 by Molmil
Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin
Descriptor: Catenin alpha-1, Vinculin
Authors:Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I.
Deposit date:2012-03-05
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.304 Å)
Cite:Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin
To be Published
6L6R
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BU of 6l6r by Molmil
Crystal structure of LRP6 E1E2-SOST complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Choi, H.-J, Kim, J.
Deposit date:2019-10-29
Release date:2020-10-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Sclerostin inhibits Wnt signaling through tandem interaction with two LRP6 ectodomains.
Nat Commun, 11, 2020
4R11
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BU of 4r11 by Molmil
A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo
Descriptor: Cadherin-related hmr-1, IODIDE ION, Protein humpback-2
Authors:Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I.
Deposit date:2014-08-03
Release date:2015-04-29
Method:X-RAY DIFFRACTION (2.789 Å)
Cite:A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
4R0Z
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BU of 4r0z by Molmil
A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo
Descriptor: FORMIC ACID, Protein humpback-2
Authors:Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I.
Deposit date:2014-08-03
Release date:2015-04-29
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
4R10
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BU of 4r10 by Molmil
A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo
Descriptor: 1,2-ETHANEDIOL, Cadherin-related hmr-1, Protein humpback-2, ...
Authors:Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I.
Deposit date:2014-08-03
Release date:2015-04-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
5DZZ
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BU of 5dzz by Molmil
Structural characterization of intermediate filaments binding domain of desmoplakin
Descriptor: Desmoplakin
Authors:Choi, H.-J, Weis, W.I.
Deposit date:2015-09-26
Release date:2016-03-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the Intermediate Filament-Binding Region of Desmoplakin.
Plos One, 11, 2016
1PRX
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BU of 1prx by Molmil
HORF6 A NOVEL HUMAN PEROXIDASE ENZYME
Descriptor: HORF6
Authors:Choi, H.-J, Kang, S.W, Yang, C.-H, Rhee, S.G, Ryu, S.-E.
Deposit date:1998-04-03
Release date:1998-06-17
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a novel human peroxidase enzyme at 2.0 A resolution.
Nat.Struct.Biol., 5, 1998
3IFQ
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BU of 3ifq by Molmil
Interction of plakoglobin and beta-catenin with desmosomal cadherins
Descriptor: E-cadherin, SULFATE ION, plakoglobin
Authors:Choi, H.-J, Gross, J.C, Pokutta, S, Weis, W.I.
Deposit date:2009-07-24
Release date:2009-09-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Interactions of plakoglobin and beta-catenin with desmosomal cadherins: basis of selective exclusion of alpha- and beta-catenin from desmosomes.
J.Biol.Chem., 284, 2009
3R6N
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BU of 3r6n by Molmil
Crystal structure of a rigid four spectrin repeat fragment of the human desmoplakin plakin domain
Descriptor: (4S,5S)-1,2-DITHIANE-4,5-DIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Desmoplakin
Authors:Choi, H.-J, Weis, W.I.
Deposit date:2011-03-22
Release date:2011-05-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal structure of a rigid four-spectrin-repeat fragment of the human desmoplakin plakin domain.
J.Mol.Biol., 409, 2011
8W77
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BU of 8w77 by Molmil
Human Consensus Olfactory Receptor OR52c in apo state, OR52c only
Descriptor: Human Consensus Olfactory Receptor OR52c in apo state, receptor only,Soluble cytochrome b562
Authors:Choi, C.W, Bae, J, Choi, H.-J, Kim, J.
Deposit date:2023-08-30
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family.
Nat Commun, 14, 2023
8HTI
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BU of 8hti by Molmil
Human Consensus Olfactory Receptor OR52c in Complex with Octanoic Acid (OCA) and G Protein
Descriptor: Consensus Olfactory Receptor OR52c, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Choi, C.W, Bae, J, Choi, H.-J, Kim, J.
Deposit date:2022-12-21
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family.
Nat Commun, 14, 2023
8J46
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BU of 8j46 by Molmil
Human Consensus Olfactory Receptor OR52c in apo state, OR52c-bRIL
Descriptor: Olfactory receptor OR52c,Soluble cytochrome b562
Authors:Choi, C.W, Bae, J, Choi, H.-J, Kim, J.
Deposit date:2023-04-19
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family.
Nat Commun, 14, 2023
1ATU
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BU of 1atu by Molmil
UNCLEAVED ALPHA-1-ANTITRYPSIN
Descriptor: ALPHA-1-ANTITRYPSIN
Authors:Ryu, S.-E, Choi, H.-J.
Deposit date:1997-05-11
Release date:1997-08-20
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved alpha1-antitrypsin at 2.7 A.
Structure, 4, 1996
8HTG
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BU of 8htg by Molmil
Crystal structure of Golf in complex with GTP-gamma S and Mg
Descriptor: 1,2-ETHANEDIOL, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Guanine nucleotide-binding protein G(olf) subunit alpha, ...
Authors:Kang, H, Choi, H.-J.
Deposit date:2022-12-21
Release date:2023-12-20
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family.
Nat Commun, 14, 2023
8JWU
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BU of 8jwu by Molmil
PHD Finger Protein 7 (PHF7) fused to UBE2D2 via a (GSGG)3 linker
Descriptor: PHD finger protein 7,Ubiquitin-conjugating enzyme E2 D2, ZINC ION
Authors:Lee, H.S, Bang, I, Choi, H.-J.
Deposit date:2023-06-29
Release date:2023-12-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Molecular basis for PHF7-mediated ubiquitination of histone H3.
Genes Dev., 37, 2023
8JWJ
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BU of 8jwj by Molmil
PHD Finger Protein 7 (PHF7) in complex with UBE2D2
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, PHD finger protein 7, ...
Authors:Lee, H.S, Bang, I, Choi, H.-J.
Deposit date:2023-06-29
Release date:2023-12-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Molecular basis for PHF7-mediated ubiquitination of histone H3.
Genes Dev., 37, 2023
8JWS
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BU of 8jws by Molmil
ePHD domain of PHD Finger Protein 7 (PHF7)
Descriptor: 1,2-ETHANEDIOL, PHD finger protein 7, ZINC ION
Authors:Bang, I, Lee, H.S, Choi, H.-J.
Deposit date:2023-06-29
Release date:2023-12-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for PHF7-mediated ubiquitination of histone H3.
Genes Dev., 37, 2023
5ZJD
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BU of 5zjd by Molmil
Lactate dehydrogenase with NADH and MLA
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase A chain, MALONATE ION
Authors:Han, C.W, Jang, S.B.
Deposit date:2018-03-20
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid.
Cancers (Basel), 11, 2019
5ZJE
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BU of 5zje by Molmil
LDHA-mla
Descriptor: L-lactate dehydrogenase A chain, MALONATE ION
Authors:Han, C.W, Jang, S.B.
Deposit date:2018-03-20
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.929 Å)
Cite:Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid.
Cancers (Basel), 11, 2019
5ZJF
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BU of 5zjf by Molmil
LDHA-MA
Descriptor: 5,5'-[(2R,3S)-2,3-dimethylbutane-1,4-diyl]bis(2H-1,3-benzodioxole), L-lactate dehydrogenase A chain
Authors:Han, C.W, Jang, S.B.
Deposit date:2018-03-20
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.602 Å)
Cite:Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid.
Cancers (Basel), 11, 2019
7YON
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BU of 7yon by Molmil
Complex structure of Neuropeptide Y Y2 receptor in complex with PYY(3-36) and Gi
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Kang, H, Park, C, Kim, J, Choi, H.-J.
Deposit date:2022-08-01
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling.
Structure, 31, 2023
7YOO
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BU of 7yoo by Molmil
Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ...
Authors:Kang, H, Park, C, Kim, J, Choi, H.-J.
Deposit date:2022-08-01
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling.
Structure, 31, 2023
4KRR
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BU of 4krr by Molmil
Crystal structure of Drosophila WntD N-terminal domain-linker (residues 31-240)
Descriptor: GLYCEROL, SODIUM ION, Wnt inhibitor of Dorsal protein
Authors:Chu, M.L.-H, Choi, H.-J, Ahn, V.E, Daniels, D.L, Nusse, R, Weis, W.I.
Deposit date:2013-05-16
Release date:2013-07-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.124 Å)
Cite:Structural Studies of Wnts and Identification of an LRP6 Binding Site.
Structure, 21, 2013
4ONS
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BU of 4ons by Molmil
Structural and thermodynamic characterization of cadherin-beta-catenin-alpha-catenin complex formation
Descriptor: Catenin alpha-2, Catenin beta-1
Authors:Pokutta, S, Choi, H.-J, Ahlsen, G, Hansen, S.D, Weis, W.I.
Deposit date:2014-01-29
Release date:2014-04-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and Thermodynamic Characterization of Cadherin beta-Catenin alpha-Catenin Complex Formation.
J.Biol.Chem., 289, 2014

 

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