Author results

1J97
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PHOSPHO-ASPARTYL INTERMEDIATE ANALOGUE OF PHOSPHOSERINE PHOSPHATASE
Descriptor:Phosphoserine Phosphatase, MAGNESIUM ION, PHOSPHATE ION
Authors:Cho, H., Wang, W., Kim, R., Yokota, H., Damo, S., Kim, S.-H., Wemmer, D., Kustu, S., Yan, D., Berkeley Structural Genomics Center (BSGC)
Deposit date:2001-05-24
Release date:2001-07-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:BeF(3)(-) acts as a phosphate analog in proteins phosphorylated on aspartate: structure of a BeF(3)(-) complex with phosphoserine phosphatase.
Proc.Natl.Acad.Sci.USA, 98, 2001
1NP3
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CRYSTAL STRUCTURE OF CLASS I ACETOHYDROXY ACID ISOMEROREDUCTASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:Ketol-acid reductoisomerase
Authors:Ahn, H.J., Eom, S.J., Yoon, H.-J., Lee, B.I., Cho, H., Suh, S.W.
Deposit date:2003-01-17
Release date:2003-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Class I Acetohydroxy Acid Isomeroreductase from Pseudomonas aeruginosa
J.Mol.Biol., 328, 2003
3HSF
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HEAT SHOCK TRANSCRIPTION FACTOR (HSF)
Descriptor:HEAT SHOCK TRANSCRIPTION FACTOR
Authors:Damberger, F.F., Pelton, J.G., Liu, C., Cho, H., Harrison, C.J., Nelson, H.C.M., Wemmer, D.E.
Deposit date:1995-08-07
Release date:1995-11-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Refined solution structure and dynamics of the DNA-binding domain of the heat shock factor from Kluyveromyces lactis.
J.Mol.Biol., 254, 1995
1BTO
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HORSE LIVER ALCOHOL DEHYDROGENASE COMPLEXED TO NADH AND (1S,3R)3-BUTYLTHIOLANE 1-OXIDE
Descriptor:LIVER ALCOHOL DEHYDROGENASE, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Ramaswamy, S., Plapp, B.V.
Deposit date:1996-11-08
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Flexibility of liver alcohol dehydrogenase in stereoselective binding of 3-butylthiolane 1-oxides.
Biochemistry, 36, 1997
3BTO
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HORSE LIVER ALCOHOL DEHYDROGENASE COMPLEXED TO NADH AND (1S,3S)3-BUTYLTHIOLANE 1-OXIDE
Descriptor:LIVER ALCOHOL DEHYDROGENASE, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Ramaswamy, S., Plapp, B.V.
Deposit date:1996-11-08
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Flexibility of liver alcohol dehydrogenase in stereoselective binding of 3-butylthiolane 1-oxides.
Biochemistry, 36, 1997
5ZXB
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CRYSTAL STRUCTURE OF ACK1 WITH COMPOUND 10D
Descriptor:Activated CDC42 kinase 1, N-{3-[7-{[6-(4-acetylpiperazin-1-yl)pyridin-3-yl]amino}-1-methyl-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl}-3-(trifluoromethyl)benzamide
Authors:Hong, E.M., Kim, H.L., Sim, T.B.
Deposit date:2018-05-18
Release date:2018-09-26
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:First SAR Study for Overriding NRAS Mutant Driven Acute Myeloid Leukemia.
J. Med. Chem., 61, 2018
5UFP
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CRYSTAL STRUCTURE OF PT2399 BOUND TO HIF2A-B*:ARNT-B* COMPLEX
Descriptor:Endothelial PAS domain-containing protein 1, Aryl hydrocarbon receptor nuclear translocator, 3-({(1S)-7-[(difluoromethyl)sulfonyl]-2,2-difluoro-1-hydroxy-2,3-dihydro-1H-inden-4-yl}oxy)-5-fluorobenzonitrile
Authors:Du, X.
Deposit date:2017-01-05
Release date:2017-01-25
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:On-target efficacy of a HIF-2 alpha antagonist in preclinical kidney cancer models.
Nature, 539, 2016
6D0Y
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X-RAY CRYSTAL STRUCTURE OF PGC-1BETA C-TERMINUS BOUND TO THE CBP80-CBP20 CAP BINDING COMPLEX
Descriptor:Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, Peroxisome proliferator-activated receptor gamma coactivator 1-beta, ...
Authors:Gleghorn, M.L., Maquat, L.E.
Deposit date:2018-04-11
Release date:2018-04-25
Last modified:2018-05-09
Method:X-RAY DIFFRACTION (2.676 Å)
Cite:Transcriptional coactivator PGC-1 alpha contains a novel CBP80-binding motif that orchestrates efficient target gene expression.
Genes Dev., 32, 2018
4UIP
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THE COMPLEX STRUCTURE OF EXTRACELLULAR DOMAIN OF EGFR WITH REPEBODY (RAC1).
Descriptor:EPIDERMAL GROWTH FACTOR RECEPTOR, REPEBODY (RAC1), N-ACETYL-D-GLUCOSAMINE
Authors:Kang, Y.J., Cha, Y.J., Cho, H.S., Lee, J.J., Kim, H.S.
Deposit date:2015-03-31
Release date:2015-11-25
Last modified:2017-03-15
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Enzymatic Prenylation and Oxime Ligation for the Synthesis of Stable and Homogeneous Protein-Drug Conjugates for Targeted Therapy.
Angew.Chem.Int.Ed.Engl., 54, 2015
4ZG0
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CRYSTAL STRUCTURE OF MOUSE SYNDESMOS PROTEIN
Descriptor:Protein syndesmos
Authors:Lee, I., Kim, H., Yoo, J., Cho, H., Lee, W.
Deposit date:2015-04-22
Release date:2016-04-20
Last modified:2016-06-01
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:Crystal structure of syndesmos and its interaction with Syndecan-4 proteoglycan
Biochem.Biophys.Res.Commun., 463, 2015
5G28
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THE CRYSTAL STRUCTURE OF LIGHT-DRIVEN CHLORIDE PUMP CLR AT PH 6.0.
Descriptor:CHLORIDE PUMPING RHODOPSIN, CHLORIDE ION, RETINAL, ...
Authors:Kim, K.L., Kwon, S.K., Jun, S.H., Cha, J.S., Kim, H.Y., Kim, J.H., Cho, H.S.
Deposit date:2016-04-07
Release date:2016-10-19
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Crystal Structure and Functional Characterization of a Light-Driven Chloride Pump Having an Ntq Motif.
Nat.Commun., 7, 2016
5G2A
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THE CRYSTAL STRUCTURE OF LIGHT-DRIVEN CHLORIDE PUMP CLR AT PH 6.0 WITH BROMIDE ION.
Descriptor:CHLORIDE PUMPING RHODOPSIN, BROMIDE ION, RETINAL
Authors:Kim, K.L., Kwon, S.K., Jun, S.H., Cha, J.S., Kim, H.Y., Kim, J.H., Cho, H.S.
Deposit date:2016-04-07
Release date:2016-10-19
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Crystal Structure and Functional Characterization of a Light-Driven Chloride Pump Having an Ntq Motif.
Nat.Commun., 7, 2016
5G2C
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THE CRYSTAL STRUCTURE OF LIGHT-DRIVEN CHLORIDE PUMP CLR (T102D) MUTANT AT PH 4.5.
Descriptor:CHLORIDE PUMPING RHODOPSIN, OLEIC ACID, CHLORIDE ION, ...
Authors:Kim, K.L., Kwon, S.K., Jun, S.H., Cha, J.S., Kim, H.Y., Kim, J.H., Cho, H.S.
Deposit date:2016-04-07
Release date:2016-10-19
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystal Structure and Functional Characterization of a Light-Driven Chloride Pump Having an Ntq Motif.
Nat.Commun., 7, 2016
5G2D
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THE CRYSTAL STRUCTURE OF LIGHT-DRIVEN CHLORIDE PUMP CLR (T102N) MUTANT AT PH 4.5.
Descriptor:CHLORIDE PUMP RHODOPSIN, OLEIC ACID, RETINAL, ...
Authors:Kim, K.L., Kwon, S.K., Jun, S.H., Cha, J.S., Kim, H.Y., Kim, J.H., Cho, H.S.
Deposit date:2016-04-07
Release date:2016-10-19
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure and Functional Characterization of a Light-Driven Chloride Pump Having an Ntq Motif.
Nat.Commun., 7, 2016
5G54
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THE CRYSTAL STRUCTURE OF LIGHT-DRIVEN CHLORIDE PUMP CLR AT PH 4.5
Descriptor:CHLORIDE PUMP RHODOPSIN, CHLORIDE ION, OLEIC ACID, ...
Authors:Kim, K.L., Kwon, S.K., Jun, S.H., Cha, J.S., Kim, H.Y., Kim, J.H., Cho, H.S.
Deposit date:2016-05-19
Release date:2016-10-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure and Functional Characterization of a Light-Driven Chloride Pump Having an Ntq Motif.
Nat.Commun., 7, 2016
2NA1
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ULD COMPLEX
Descriptor:Polycomb complex protein BMI-1, Polyhomeotic-like 2
Authors:Cierpicki, T., Gray, F., Cho, H.
Deposit date:2015-12-17
Release date:2016-11-16
Last modified:2018-01-31
Method:SOLUTION NMR
Cite:BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerization.
Nat Commun, 7, 2016
4B18
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THE CRYSTAL STRUCTURE OF HUMAN IMPORTIN ALPHA 5 WITH TERT NLS PEPTIDE
Descriptor:IMPORTIN SUBUNIT ALPHA-1, TELOMERASE REVERSE TRANSCRIPTASE
Authors:Kim, K.L., Yoo, J.H., Cho, H.S.
Deposit date:2012-07-08
Release date:2013-09-04
Last modified:2015-07-01
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Akt-Mediated Phosphorylation Increases the Binding Affinity of Htert for Importin Alpha to Promote Nuclear Translocation.
J.Cell.Sci., 128, 2015
4XV1
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B-RAF KINASE V600E ONCOGENIC MUTANT IN COMPLEX WITH PLX7904
Descriptor:Serine/threonine-protein kinase B-raf, N'-(3-{[5-(2-cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)-N-ethyl-N-methylsulfuric diamide
Authors:Zhang, Y., Zhang, C.
Deposit date:2015-01-26
Release date:2015-10-28
Last modified:2015-11-04
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:RAF inhibitors that evade paradoxical MAPK pathway activation.
Nature, 526, 2015
4XV2
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B-RAF KINASE V600E ONCOGENIC MUTANT IN COMPLEX WITH DABRAFENIB
Descriptor:Serine/threonine-protein kinase B-raf, Dabrafenib
Authors:zhang, Y., zhang, c.
Deposit date:2015-01-26
Release date:2015-10-28
Last modified:2015-11-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:RAF inhibitors that evade paradoxical MAPK pathway activation.
Nature, 526, 2015
4XV3
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B-RAF KINASE V600E ONCOGENIC MUTANT IN COMPLEX WITH PLX7922
Descriptor:Serine/threonine-protein kinase B-raf, N'-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-N-ethyl-N-methylsulfuric diamide
Authors:Zhang, Y., Zhang, C.
Deposit date:2015-01-26
Release date:2015-10-28
Last modified:2015-11-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:RAF inhibitors that evade paradoxical MAPK pathway activation.
Nature, 526, 2015
4XV9
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B-RAF KINASE DOMAIN IN COMPLEX WITH PLX5568
Descriptor:Serine/threonine-protein kinase B-raf, N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}-4-(trifluoromethyl)benzenesulfonamide, SULFATE ION
Authors:zhang, Y., zhang, c., wang, w.
Deposit date:2015-01-26
Release date:2015-10-28
Last modified:2015-11-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:RAF inhibitors that evade paradoxical MAPK pathway activation.
Nature, 526, 2015
4B6H
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STRUCTURE OF HDCP1A IN COMPLEX WITH PROLINE RICH SEQUENCE OF PNRC2
Descriptor:MRNA-DECAPPING ENZYME 1A, PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR 2
Authors:Lai, T., Song, H.
Deposit date:2012-08-13
Release date:2013-03-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis of the Pnrc2-Mediated Link between Mrna Surveillance and Decapping.
Structure, 20, 2012
4HQM
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THE CRYSTAL STRUCTURE OF QSRR-MENADIONE COMPLEX
Descriptor:QsrR protein, 2-methylnaphthalene-1,4-diol
Authors:Ji, Q., Zhang, L., Jones, M.B., Sun, F., Deng, X., Liang, H., Brugarolas, P., Gao, N., Peterson, S.N., Lan, L., Bae, T., He, C.
Deposit date:2012-10-25
Release date:2013-03-06
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR.
Proc.Natl.Acad.Sci.USA, 110, 2013
3C4C
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B-RAF KINASE IN COMPLEX WITH PLX4720
Descriptor:B-Raf proto-oncogene serine/threonine-protein kinase, N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide
Authors:Zhang, K.Y.J., Wang, W.
Deposit date:2008-01-29
Release date:2008-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
Proc.Natl.Acad.Sci.Usa, 105, 2008
3C4E
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PIM-1 KINASE DOMAIN IN COMPLEX WITH 3-AMINOPHENYL-7-AZAINDOLE
Descriptor:Proto-oncogene serine/threonine-protein kinase Pim-1, IMIDAZOLE, N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine
Authors:Zhang, K.Y.J., Wang, W.
Deposit date:2008-01-29
Release date:2008-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
Proc.Natl.Acad.Sci.Usa, 105, 2008
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