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5WOE
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SOLUTION STRUCTURE OF THE SORTING NEXIN 25 PHOX-HOMOLOGY DOMAIN
Descriptor:Sorting nexin-25
Authors:Chin, Y.K.Y., Mas, C., Mobli, M., Collins, B.M.
Deposit date:2017-08-01
Release date:2018-08-08
Method:SOLUTION NMR
Cite:Solution structure of the sorting nexin 25 phox-homology domain reveals a novel phosphoinositide binding mechanism
To Be Published
5WLX
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SOLUTION STRUCTURE OF KAPPA-THERAPHOTOXIN-AA1A
Descriptor:Kappa-theraphotoxin-Aa1a
Authors:Chin, Y.K.Y., Ma, L., King, G.F.
Deposit date:2017-07-28
Release date:2018-08-01
Last modified:2019-02-27
Method:SOLUTION NMR
Cite:Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target.
Biochem. Pharmacol., 158, 2018
6A90
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COMPLEX OF VOLTAGE-GATED SODIUM CHANNEL NAVPAS FROM AMERICAN COCKROACH PERIPLANETA AMERICANA AND DC1A
Descriptor:Sodium channel protein PaFPC1, Mu-diguetoxin-Dc1a, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Shen, H.Z., li, Z.Q., Jiang, Y., Pan, X.J., Wu, J.P., Cristofori-Armstrong, B., Smith, J.J., Chin, Y.K.Y., Lei, J.L., Zhou, Q., King, G.F., Yan, N.
Deposit date:2018-07-11
Release date:2018-08-08
Last modified:2018-12-26
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis for the modulation of voltage-gated sodium channels by animal toxins.
Science, 362, 2018
6A91
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COMPLEX OF VOLTAGE-GATED SODIUM CHANNEL NAVPAS FROM AMERICAN COCKROACH PERIPLANETA AMERICANA BOUND WITH SAXITOXIN AND DC1A
Descriptor:Sodium channel protein PaFPC1, Mu-diguetoxin-Dc1a, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Shen, H.Z., li, Z.Q., Jiang, Y., Pan, X.J., Wu, J.P., Cristofori-Armstrong, B., Smith, J.J., Chin, Y.K.Y., Lei, J.L., Zhou, Q., King, G.F., Yan, N.
Deposit date:2018-07-11
Release date:2018-08-08
Last modified:2018-12-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for the modulation of voltage-gated sodium channels by animal toxins.
Science, 362, 2018
6A95
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COMPLEX OF VOLTAGE-GATED SODIUM CHANNEL NAVPAS FROM AMERICAN COCKROACH PERIPLANETA AMERICANA BOUND WITH TETRODOTOXIN AND DC1A
Descriptor:Sodium channel protein PaFPC1, Mu-diguetoxin-Dc1a, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Shen, H.Z., li, Z.Q., Jiang, Y., Pan, X.J., Wu, J.P., Cristofori-Armstrong, B., Smith, J.J., Chin, Y.K.Y., Lei, J.L., Zhou, Q., King, G.F., Yan, N.
Deposit date:2018-07-11
Release date:2018-08-08
Last modified:2018-12-26
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis for the modulation of voltage-gated sodium channels by animal toxins.
Science, 362, 2018
2MQF
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NMR STRUCTURE OF SPIDER TOXIN-TRTX-HHN2B
Descriptor:Mu-theraphotoxin-Hhn2b
Authors:Klint, J.K., Chin, Y.K.Y., Mobli, M.
Deposit date:2014-06-19
Release date:2015-07-15
Last modified:2015-12-23
Method:SOLUTION NMR
Cite:Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7
Mol.Pharmacol., 88, 2015
2MXO
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NMR STRUCTURE OF SPIDER TOXIN- G7W/N24S MUTANT OF TRTX-HHN2B
Descriptor:Mu-theraphotoxin-Hhn2b
Authors:Klint, J.K., Chin, Y.K.Y., Mobli, M.
Deposit date:2015-01-08
Release date:2015-12-23
Method:SOLUTION NMR
Cite:Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7
Mol.Pharmacol., 88, 2015
6AZA
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NMR STRUCTURE OF SEA ANEMONE TOXIN KAPPA-ACTITOXIN-ATE1A
Descriptor:ARG-CYS-LYS-THR-CYS-SER-LYS-GLY-ARG-CYS-ARG-PRO-LYS-PRO-ASN-CYS-GLY-NH2
Authors:Chin, Y.K.-Y., Madio, B., King, G.F., Undheim, E.A.B.
Deposit date:2017-09-10
Release date:2018-09-12
Last modified:2018-11-14
Method:SOLUTION NMR
Cite:PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold.
Cell. Mol. Life Sci., 75, 2018