6DSX
| Bst DNA polymerase I post-chemistry (n+1 with dATP soak) structure | Descriptor: | DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... | Authors: | Chim, N, Jackson, L.N, Chaput, J.C. | Deposit date: | 2018-06-14 | Release date: | 2018-10-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway. Elife, 7, 2018
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6DSV
| Bst DNA polymerase I post-chemistry (n+2) structure | Descriptor: | DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... | Authors: | Chim, N, Jackson, L.N, Chaput, J.C. | Deposit date: | 2018-06-14 | Release date: | 2018-10-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway. Elife, 7, 2018
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6DSW
| Bst DNA polymerase I pre-chemistry (n) structure | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*G)-3'), DNA (5'-D(P*AP*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ... | Authors: | Chim, N, Jackson, L.N, Chaput, J.C. | Deposit date: | 2018-06-14 | Release date: | 2018-10-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.589 Å) | Cite: | Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway. Elife, 7, 2018
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6DSY
| Bst DNA polymerase I post-chemistry (n+1) structure | Descriptor: | DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... | Authors: | Chim, N, Jackson, L.N, Chaput, J.C. | Deposit date: | 2018-06-14 | Release date: | 2018-10-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway. Elife, 7, 2018
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6DSU
| Bst DNA polymerase I pre-insertion complex structure | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ... | Authors: | Chim, N, Jackson, L.N, Chaput, J.C. | Deposit date: | 2018-06-14 | Release date: | 2018-10-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway. Elife, 7, 2018
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1PGY
| Solution structure of the UBA domain in Saccharomyces cerevisiae protein, Swa2p | Descriptor: | Swa2p | Authors: | Chim, N, Gall, W.E, Xiao, J, Harris, M.P, Graham, T.R, Krezel, A.M. | Deposit date: | 2003-05-28 | Release date: | 2004-03-23 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of the ubiquitin-binding domain in Swa2p from Saccharomyces cerevisiae. PROTEINS: STRUCT.,FUNCT.,GENET., 54, 2004
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5VU5
| TNA polymerase, apo | Descriptor: | DNA polymerase | Authors: | Chim, N, Chaput, J.C. | Deposit date: | 2017-05-18 | Release date: | 2017-12-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5VU7
| TNA polymerase, open ternary complex | Descriptor: | 5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXYTETRAHYDROFURAN-3-YL DIHYDROGEN PHOSPHATE, DNA polymerase, DNA template, ... | Authors: | Chim, N, Chaput, J.C. | Deposit date: | 2017-05-18 | Release date: | 2017-12-06 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5VU9
| TNA polymerase, translocated product | Descriptor: | DNA polymerase, DNA template, DNA/TNA hybrid primer | Authors: | Chim, N, Chaput, J.C. | Deposit date: | 2017-05-18 | Release date: | 2017-12-06 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5VU8
| TNA polymerase, closed ternary complex | Descriptor: | DNA polymerase, DNA template, DNA/TNA hybrid primer, ... | Authors: | Chim, N, Chaput, J.C. | Deposit date: | 2017-05-18 | Release date: | 2017-12-06 | Last modified: | 2017-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for TNA synthesis by an engineered TNA polymerase. Nat Commun, 8, 2017
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5VU6
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3HX9
| Structure of heme-degrader, MhuD (Rv3592), from Mycobacterium tuberculosis with two hemes bound in its active site | Descriptor: | CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, Protein Rv3592 | Authors: | Chim, N, Nguyen, T.Q, Iniguez, A, Goulding, C.W. | Deposit date: | 2009-06-19 | Release date: | 2009-12-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Unusual Diheme Conformation of the Heme-Degrading Protein from Mycobacterium tuberculosis J.Mol.Biol., 395, 2009
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3IOS
| Structure of MTB dsbF in its mixed oxidized and reduced forms | Descriptor: | Disulfide bond forming protein (DsbF) | Authors: | Chim, N, Goulding, C.W. | Deposit date: | 2009-08-14 | Release date: | 2010-01-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | An extracellular disulfide bond forming protein (DsbF) from Mycobacterium tuberculosis: structural, biochemical, and gene expression analysis. J.Mol.Biol., 396, 2010
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7K5U
| Bst DNA polymerase I time-resolved structure, 48 hr post dATP and dCTP addition | Descriptor: | DNA (5'-D(P*CP*GP*AP*TP*CP*AP*CP*GP*TP*AP*C)-3'), DNA (5'-D(P*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*C)-3'), DNA polymerase I, ... | Authors: | Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. | Deposit date: | 2020-09-17 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
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7K5P
| Bst DNA polymerase I time-resolved structure, 4 min post dATP addition | Descriptor: | DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... | Authors: | Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. | Deposit date: | 2020-09-17 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
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7K5R
| Bst DNA polymerase I time-resolved structure, 120 min post dATP addition | Descriptor: | DNA (5'-D(P*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... | Authors: | Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. | Deposit date: | 2020-09-17 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
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7K5S
| Bst DNA polymerase I time-resolved structure, 4 hr post dATP and dCTP addition | Descriptor: | DNA (5'-D(*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*AP*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*C)-3'), DNA polymerase I, ... | Authors: | Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. | Deposit date: | 2020-09-17 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
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7K5O
| Bst DNA polymerase I time-resolved structure, 1 min post dATP addition | Descriptor: | DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... | Authors: | Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. | Deposit date: | 2020-09-17 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
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7K5Q
| Bst DNA polymerase I time-resolved structure, 8 min post dATP addition | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(P*G*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ... | Authors: | Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. | Deposit date: | 2020-09-17 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
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7K5T
| Bst DNA polymerase I time-resolved structure, 25.5 hr post dATP and dCTP addition | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*C)-3'), ... | Authors: | Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C. | Deposit date: | 2020-09-17 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Following replicative DNA synthesis by time-resolved X-ray crystallography. Nat Commun, 12, 2021
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4Y0L
| Mycobacterial membrane protein MmpL11D2 | Descriptor: | IODIDE ION, Putative membrane protein mmpL11, SULFATE ION | Authors: | Torres, R, Chim, N, Goulding, C.W. | Deposit date: | 2015-02-06 | Release date: | 2015-08-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The Structure and Interactions of Periplasmic Domains of Crucial MmpL Membrane Proteins from Mycobacterium tuberculosis. Chem.Biol., 22, 2015
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6MU4
| Bst DNA polymerase I FANA/DNA binary complex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(P*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA polymerase I, ... | Authors: | Jackson, L.N, Chim, N, Chaput, J.C. | Deposit date: | 2018-10-22 | Release date: | 2019-06-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase. Nucleic Acids Res., 47, 2019
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6MU5
| Bst DNA polymerase I TNA/DNA binary complex | Descriptor: | DNA (5'-D(P*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA polymerase I, SULFATE ION, ... | Authors: | Jackson, L.N, Chim, N, Chaput, J.C. | Deposit date: | 2018-10-22 | Release date: | 2019-06-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.912 Å) | Cite: | Crystal structures of a natural DNA polymerase that functions as an XNA reverse transcriptase. Nucleic Acids Res., 47, 2019
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2QH3
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2QH2
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