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4A3J
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BU of 4a3j by Molmil
RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid and soaked with GMPCPP
Descriptor: 5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*TP*CP*BRUP*AP*CP*CP *TP*GP*AP*AP*CP*AP*AP*CP*TP*AP*AP*CP)-3', 5'-D(*GP*TP*AP*GP*AP*AP*AP*GP*CP*TP*AP*GP*CP*TP)-3', 5'-R(*CP*AP)-3', ...
Authors:Cheung, A.C.M, Sainsbury, S, Cramer, P.
Deposit date:2011-09-30
Release date:2011-12-07
Last modified:2011-12-14
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural Basis of Initial RNA Polymerase II Transcription.
Embo J., 30, 2011
4A3K
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BU of 4a3k by Molmil
RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid
Descriptor: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*DTP *TP*TP*CP*CP*BRU*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP)-3', 5'-R(*AP*CP*CP*AP*GP*GP*AP)-3', ...
Authors:Cheung, A.C.M, Sainsbury, S, Cramer, P.
Deposit date:2011-09-30
Release date:2011-12-07
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural Basis of Initial RNA Polymerase II Transcription.
Embo J., 30, 2011
6ZGA
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BU of 6zga by Molmil
COPII on membranes, inner coat
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, PRO-PRO-PRO, ...
Authors:Zanetti, G, Hutchings, J, Cheung, A.C.M.
Deposit date:2020-06-18
Release date:2021-02-17
Last modified:2021-04-14
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network.
Nat Commun, 12, 2021
7OQ4
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BU of 7oq4 by Molmil
Cryo-EM structure of the ATV RNAP Inhibitory Protein (RIP) bound to the DNA-binding channel of the host's RNA polymerase
Descriptor: Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ...
Authors:Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F.
Deposit date:2021-06-02
Release date:2021-08-25
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
7OQY
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BU of 7oqy by Molmil
Cryo-EM structure of the cellular negative regulator TFS4 bound to the archaeal RNA polymerase
Descriptor: Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ...
Authors:Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F.
Deposit date:2021-06-04
Release date:2021-08-25
Last modified:2021-11-03
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
7OK0
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BU of 7ok0 by Molmil
Cryo-EM structure of the Sulfolobus acidocaldarius RNA polymerase at 2.88 A
Descriptor: Conserved protein, DNA-directed RNA polymerase subunit A', DNA-directed RNA polymerase subunit A'', ...
Authors:Pilotto, S, Fouqueau, T, Lukoyanova, N, Sheppard, C, Lucas-Staat, S, Diaz-Santin, L.M, Matelska, D, Prangishvili, D, Cheung, A.C.M, Werner, F.
Deposit date:2021-05-17
Release date:2021-08-25
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of RNA polymerase inhibition by viral and host factors.
Nat Commun, 12, 2021
3HOV
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BU of 3hov by Molmil
Complete RNA polymerase II elongation complex II
Descriptor: 5'-D(*AP*GP*CP*TP*CP*AP*A*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*T*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*CP*A)-3', ...
Authors:Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P.
Deposit date:2009-06-03
Release date:2009-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
Mol.Cell, 34, 2009
3HOW
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BU of 3how by Molmil
Complete RNA polymerase II elongation complex III with a T-U mismatch and a frayed RNA 3'-uridine
Descriptor: 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*U)-3', ...
Authors:Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P.
Deposit date:2009-06-03
Release date:2009-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
Mol.Cell, 34, 2009
3HOY
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BU of 3hoy by Molmil
Complete RNA polymerase II elongation complex VI
Descriptor: 5'-D(*CP*CP*AP*AP*GP*CP*TP*CP*AP*AP*G*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*TP*AP*CP*TP*AP*GP*TP*AP*CP*TP*GP*CP*C)-3', 5'-D(*CP*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*AP*GP*TP*AP*AP*AP*CP*TP*AP*GP*TP*AP*TP*T*GP*AP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP*T)-3', 5'-R(*UP*AP*UP*AP*UP*GP*CP*A*UP*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*A)-3', ...
Authors:Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P.
Deposit date:2009-06-03
Release date:2009-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
Mol.Cell, 34, 2009
3HOX
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BU of 3hox by Molmil
Complete RNA polymerase II elongation complex V
Descriptor: 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*AP*AP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*U)-3', ...
Authors:Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P.
Deposit date:2009-06-03
Release date:2009-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
Mol.Cell, 34, 2009
3HOZ
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BU of 3hoz by Molmil
Complete RNA polymerase II elongation complex IV with a T-U mismatch and a frayed RNA 3'-guanine
Descriptor: 5'-D(*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*C*AP*AP*GP*TP*AP*GP*TP*TP*CP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*UP*U*CP*AP*AP*CP*CP*AP*GP*GP*CP*UP*G)-3', ...
Authors:Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P.
Deposit date:2009-06-03
Release date:2009-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
Mol.Cell, 34, 2009
3HOU
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BU of 3hou by Molmil
Complete RNA polymerase II elongation complex I with a T-U mismatch
Descriptor: 5'-D(*A*AP*CP*TP*AP*CP*TP*TP*GP*AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*CP*A*AP*GP*TP*AP*GP*TP*TP*AP*TP*GP*CP*CP*(BRU)P*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*UP*GP*CP*AP*UP*U*UP*CP*GP*AP*CP*CP*AP*GP*GP*CP*U)-3', ...
Authors:Sydow, J.F, Brueckner, F, Cheung, A.C.M, Damsma, G.E, Dengl, S, Lehmann, E, Vassylyev, D, Cramer, P.
Deposit date:2009-06-03
Release date:2009-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
Mol.Cell, 34, 2009
3PO3
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BU of 3po3 by Molmil
Arrested RNA Polymerase II reactivation intermediate
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, DNA non-template strand, ...
Authors:Cheung, A.C.M, Cramer, P.
Deposit date:2010-11-21
Release date:2011-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of RNA polymerase II backtracking, arrest and reactivation.
Nature, 471, 2011
3PO2
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BU of 3po2 by Molmil
Arrested RNA Polymerase II elongation complex
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Cheung, A.C.M, Cramer, P.
Deposit date:2010-11-21
Release date:2011-03-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of RNA polymerase II backtracking, arrest and reactivation.
Nature, 471, 2011
4A3D
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BU of 4a3d by Molmil
RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid
Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
Authors:Cheung, A.C.M, Sainsbury, S, Cramer, P.
Deposit date:2011-09-30
Release date:2011-12-07
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
4A3F
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BU of 4a3f by Molmil
RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid and soaked with AMPCPP
Descriptor: 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*DTP *TP*TP*CP*C BRU*GP*GP*TP*CP*AP*TP*T)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, ...
Authors:Cheung, A.C.M, Sainsbury, S, Cramer, P.
Deposit date:2011-09-30
Release date:2011-12-07
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
4A3G
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BU of 4a3g by Molmil
RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid
Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
Authors:Cheung, A.C.M, Sainsbury, S, Cramer, P.
Deposit date:2011-09-30
Release date:2012-02-08
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
4A3I
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BU of 4a3i by Molmil
RNA Polymerase II binary complex with DNA
Descriptor: 5'-D(*GP*GP*CP*AP*CP*AP*AP*CP*TP*GP*CP*GP*GP*CP*T)-3', DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ...
Authors:Cheung, A.C.M, Sainsbury, S, Cramer, P.
Deposit date:2011-09-30
Release date:2012-02-08
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
4A3L
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BU of 4a3l by Molmil
RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid and soaked with AMPCPP
Descriptor: 5'-D(*AP*AP*GP*TP*AP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP *TP*TP*CP*CP*BRU*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*AP*CP*CP*AP*GP*GP*AP)-3', ...
Authors:Cheung, A.C.M, Sainsbury, S, Cramer, P.
Deposit date:2011-09-30
Release date:2011-12-07
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
4A3M
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BU of 4a3m by Molmil
RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid and soaked with AMPCPP
Descriptor: 5'-D(*AP*AP*GP*TP*AP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP* TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*AP*GP*GP*A)-3', ...
Authors:Cheung, A.C.M, Sainsbury, S, Cramer, P.
Deposit date:2011-09-30
Release date:2011-12-07
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
4A3E
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BU of 4a3e by Molmil
RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid and soaked with AMPCPP
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ...
Authors:Cheung, A.C.M, Sainsbury, S, Cramer, P.
Deposit date:2011-09-30
Release date:2011-12-07
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
4A3B
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BU of 4a3b by Molmil
RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid
Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
Authors:Cheung, A.C.M, Sainsbury, S, Cramer, P.
Deposit date:2011-09-30
Release date:2011-12-07
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
4A3C
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BU of 4a3c by Molmil
RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid
Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
Authors:Cheung, A.C.M, Sainsbury, S, Cramer, P.
Deposit date:2011-09-30
Release date:2011-11-16
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
5OJS
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BU of 5ojs by Molmil
Cryo-EM structure of the SAGA and NuA4 coactivator subunit Tra1
Descriptor: Transcription-associated protein 1
Authors:Diaz-Santin, L.M, Lukoyanova, N, Aciyan, E, Cheung, A.C.M.
Deposit date:2017-07-24
Release date:2017-08-09
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structure of the SAGA and NuA4 coactivator subunit Tra1 at 3.7 angstrom resolution.
Elife, 6, 2017
6T9K
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BU of 6t9k by Molmil
SAGA Core module
Descriptor: Protein SPT3, SAGA-associated factor 73, Transcription factor SPT20, ...
Authors:Wang, H, Cheung, A, Cramer, P.
Deposit date:2019-10-28
Release date:2020-01-29
Last modified:2020-02-19
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the transcription coactivator SAGA.
Nature, 577, 2020

 

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