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2B4S
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BU of 2b4s by Molmil
Crystal structure of a complex between PTP1B and the insulin receptor tyrosine kinase
Descriptor: Insulin receptor, SULFATE ION, Tyrosine-protein phosphatase, ...
Authors:Li, S, Depetris, R.S, Barford, D, Chernoff, J, Hubbard, S.R.
Deposit date:2005-09-26
Release date:2005-11-15
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of a Complex between Protein Tyrosine Phosphatase 1B and the Insulin Receptor Tyrosine Kinase.
Structure, 13, 2005
4EQC
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BU of 4eqc by Molmil
Crystal structure of PAK1 kinase domain in complex with FRAX597 inhibitor
Descriptor: 6-[2-chloro-4-(1,3-thiazol-5-yl)phenyl]-8-ethyl-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one, CHLORIDE ION, Serine/threonine-protein kinase PAK 1
Authors:Maksimoska, J, Marmorstein, R.
Deposit date:2012-04-18
Release date:2013-08-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas.
J.Biol.Chem., 288, 2013

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