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2RAP
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BU of 2rap by Molmil
THE SMALL G PROTEIN RAP2A IN COMPLEX WITH GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RAP2A
Authors:Cherfils, J, Menetrey, J, Lebras, G.
Deposit date:1998-05-06
Release date:1998-06-17
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS.
EMBO J., 16, 1997
1KAO
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BU of 1kao by Molmil
CRYSTAL STRUCTURE OF THE SMALL G PROTEIN RAP2A WITH GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAP2A
Authors:Cherfils, J, Menetrey, J, Le Bras, G.
Deposit date:1997-08-01
Release date:1997-12-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS.
EMBO J., 16, 1997
1NDC
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BU of 1ndc by Molmil
X-RAY STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE COMPLEXED WITH DTDP AND MG2+ AT 2 A RESOLUTION
Descriptor: MAGNESIUM ION, NUCLEOSIDE DIPHOSPHATE KINASE, THYMIDINE-5'-DIPHOSPHATE
Authors:Cherfils, J, Morera, S, Janin, J.
Deposit date:1994-04-27
Release date:1994-06-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray structure of nucleoside diphosphate kinase complexed with thymidine diphosphate and Mg2+ at 2-A resolution.
Biochemistry, 33, 1994
1PBV
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BU of 1pbv by Molmil
SEC7 DOMAIN OF THE EXCHANGE FACTOR ARNO
Descriptor: ARNO
Authors:Cherfils, J, Menetrey, J, Mathieu, M, Le Bras, G, Robineau, S, Beraud-Dufour, S, Antonny, B, Chardin, P.
Deposit date:1998-01-15
Release date:1999-03-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Sec7 domain of the Arf exchange factor ARNO.
Nature, 392, 1998
5N6O
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BU of 5n6o by Molmil
Wild type human Rac1-GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1
Authors:Cherfils, J, Ferrandez, Y.
Deposit date:2017-02-15
Release date:2017-12-27
Last modified:2020-11-18
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Allosteric inhibition of the guanine nucleotide exchange factor DOCK5 by a small molecule.
Sci Rep, 7, 2017
1KDN
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BU of 1kdn by Molmil
STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
Authors:Cherfils, J, Xu, Y.W, Morera, S, Janin, J.
Deposit date:1996-09-10
Release date:1997-04-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:AlF3 mimics the transition state of protein phosphorylation in the crystal structure of nucleoside diphosphate kinase and MgADP.
Proc.Natl.Acad.Sci.USA, 94, 1997
4Z68
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BU of 4z68 by Molmil
Hybrid structural analysis of the Arp2/3 regulator Arpin identifies its acidic tail as a primary binding epitope
Descriptor: GLU-ILE-ARG-GLU-GLN-GLY-ASP-GLY-ALA-GLU-ASP-GLU, SULFATE ION, Tankyrase-2
Authors:Fetics, S.K, Campanacci, V, Dang, I, Gautreau, A, Cherfils, J.
Deposit date:2015-04-04
Release date:2015-12-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.859 Å)
Cite:Hybrid Structural Analysis of the Arp2/3 Regulator Arpin Identifies Its Acidic Tail as a Primary Binding Epitope.
Structure, 24, 2016
3RAP
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BU of 3rap by Molmil
The small G protein Rap2 in a non catalytic complex with GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PROTEIN (G protein RAP2A)
Authors:Menetrey, J, Cherfils, J.
Deposit date:1999-05-31
Release date:1999-12-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the small G protein Rap2 in a non-catalytic complex with GTP.
Proteins, 37, 1999
5NLV
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BU of 5nlv by Molmil
Brag2 Sec7-PH (390-763)
Descriptor: IQ motif and SEC7 domain-containing protein 1
Authors:Nawrotek, A, Cherfils, J.
Deposit date:2017-04-05
Release date:2017-09-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3LTL
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BU of 3ltl by Molmil
Crystal structure of human BIG1 Sec7 domain
Descriptor: ACETIC ACID, Brefeldin A-inhibited guanine nucleotide-exchange protein 1, CALCIUM ION
Authors:Simister, P.C, Joubert, A, Cherfils, J, Biou, V.
Deposit date:2010-02-16
Release date:2011-04-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Sec7 domain structures of human BIG1 and Cytohesin1 Arf nucleotide exchange factors
To be Published
3N5C
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BU of 3n5c by Molmil
Crystal Structure of Arf6DELTA13 complexed with GDP
Descriptor: ADP-ribosylation factor 6, CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Aizel, K, Biou, V, Cherfils, J.
Deposit date:2010-05-25
Release date:2010-08-18
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:SAXS and X-ray crystallography suggest an unfolding model for the GDP/GTP conformational switch of the small GTPase Arf6.
J.Mol.Biol., 402, 2010
2J5X
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BU of 2j5x by Molmil
STRUCTURE OF THE SMALL G PROTEIN ARF6 IN COMPLEX WITH GTPGAMMAS
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ADP-RIBOSYLATION FACTOR 6, MAGNESIUM ION
Authors:Pasqualato, S, Menetrey, J, Franco, M, Cherfils, J.
Deposit date:2006-09-20
Release date:2006-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structural Gdp-GTP Cycle of Human Arf6.
Embo Rep., 2, 2001
6HJM
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BU of 6hjm by Molmil
Myxococcus xanthus MglB
Descriptor: MglB
Authors:Varela, P.F, Navaza, J, Trapani, S, Cherfils, J.
Deposit date:2018-09-04
Release date:2019-12-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus.
Nat Commun, 10, 2019
5NLY
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BU of 5nly by Molmil
Brag2 Sec7-PH (390-763), P212121
Descriptor: IQ motif and SEC7 domain-containing protein 1, PHOSPHATE ION
Authors:Nawrotek, A, Cherfils, J.
Deposit date:2017-04-05
Release date:2017-09-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6H35
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BU of 6h35 by Molmil
Myxococcus xanthus MglA bound to GDP and Pi with mixed inactive and active switch region conformations
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, GUANOSINE-5'-DIPHOSPHATE, Mutual gliding-motility protein MglA, ...
Authors:Varela, P.F, Galicia, C, Cherfils, J.
Deposit date:2018-07-17
Release date:2019-12-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus.
Nat Commun, 10, 2019
6H17
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BU of 6h17 by Molmil
Myxococcus xanthus MglA bound to GTPgammaS
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Mutual gliding-motility protein MglA, ...
Authors:Galicia, C, Cherfils, J.
Deposit date:2018-07-11
Release date:2019-11-27
Last modified:2020-11-11
Method:X-RAY DIFFRACTION (1.275 Å)
Cite:MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus.
Nat Commun, 10, 2019
6H5B
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BU of 6h5b by Molmil
Myxococcus xanthus MglA in complex with its GAP MglB and GTPgammaS
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
Authors:Galicia, C, Cherfils, J.
Deposit date:2018-07-24
Release date:2019-11-27
Last modified:2020-11-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus.
Nat Commun, 10, 2019
6HJO
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BU of 6hjo by Molmil
Myxococcus xanthus MglA bound to GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Mutual gliding-motility protein MglA
Authors:Varela, P.F, Cherfils, J.
Deposit date:2018-09-04
Release date:2019-12-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus.
Nat Commun, 10, 2019
6HJH
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BU of 6hjh by Molmil
Myxococcus xanthus MglA bound to GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Mutual gliding-motility protein MglA
Authors:Varela, P.F, Cherfils, J.
Deposit date:2018-09-03
Release date:2019-12-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus.
Nat Commun, 10, 2019
1E7Z
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BU of 1e7z by Molmil
Crystal structure of the EMAP2/RNA binding domain of the p43 protein from human aminoacyl-tRNA synthetase complex
Descriptor: ENDOTHELIAL-MONOCYTE ACTIVATING POLYPEPTIDE II, MERCURY (II) ION
Authors:Pasqualato, S, Kerjan, P, Renault, L, Menetrey, J, Mirande, M, Cherfils, J.
Deposit date:2000-09-13
Release date:2000-11-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure of the Emapii Domain of Human Aminoacyl-tRNA Synthetase Complex Reveals Evolutionary Dimeric Mimicry
Embo J., 20, 2001
1FL0
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BU of 1fl0 by Molmil
CRYSTAL STRUCTURE OF THE EMAP2/RNA-BINDING DOMAIN OF THE P43 PROTEIN FROM HUMAN AMINOACYL-TRNA SYNTHETASE COMPLEX
Descriptor: ENDOTHELIAL-MONOCYTE ACTIVATING POLYPEPTIDE II
Authors:Renault, L, Kerjan, P, Pasqualato, S, Menetrey, J, Robinson, J.-C, Kawaguchi, S, Vassylyev, D.G, Yokoyama, S, Mirande, M, Cherfils, J.
Deposit date:2000-08-11
Release date:2000-12-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the EMAPII domain of human aminoacyl-tRNA synthetase complex reveals evolutionary dimer mimicry.
EMBO J., 20, 2001
1KU1
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BU of 1ku1 by Molmil
Crystal Structure of the Sec7 Domain of Yeast GEA2
Descriptor: ARF guanine-nucleotide exchange factor 2
Authors:Renault, L, Christova, P, Guibert, B, Pasqualato, S, Cherfils, J.
Deposit date:2002-01-20
Release date:2002-03-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Mechanism of domain closure of Sec7 domains and role in BFA sensitivity.
Biochemistry, 41, 2002
2F3T
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BU of 2f3t by Molmil
Crystal Structure Of E.coli Guanylate Kinase In Complex With Ganciclovir monophosphate
Descriptor: Guanylate kinase, N9-1-HYDROXY-PROP-2-OXYMETHYL-GUANINE-3'-MONOPHOSPHATE
Authors:Hible, G, Cherfils, J.
Deposit date:2005-11-22
Release date:2006-05-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Crystal structures of GMP kinase in complex with ganciclovir monophosphate and Ap5G.
Biochimie, 88, 2006
2F3R
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BU of 2f3r by Molmil
Crystal Structure Of E.coli Guanylate Kinase In Complex With Ap5G
Descriptor: Guanylate kinase, P1-(5'-ADENOSYL)-P5-(5'-GUANOSYL) PENTAPHOSPHATE
Authors:Hible, G, Cherfils, J.
Deposit date:2005-11-22
Release date:2006-05-30
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of GMP kinase in complex with ganciclovir monophosphate and Ap5G.
Biochimie, 88, 2006
1E0S
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BU of 1e0s by Molmil
small G protein Arf6-GDP
Descriptor: ADP-ribosylation factor 6, AMMONIUM ION, BETA-MERCAPTOETHANOL, ...
Authors:Menetrey, J, Cherfils, J.
Deposit date:2000-04-06
Release date:2000-04-18
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structure of Arf6-Gdp Suggests a Basis for Guanine Nucleotide Exchange Factors Specificity
Nat.Struct.Biol., 7, 2000

 

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