Author results

2RH1
  • Download 2rh1
  • View 2rh1
Molmil generated image of 2rh1
HIGH RESOLUTION CRYSTAL STRUCTURE OF HUMAN B2-ADRENERGIC G PROTEIN-COUPLED RECEPTOR.
分子名称:beta-2-adrenergic receptor/T4-lysozyme chimera, MALTOSE, SULFATE ION, ...
著者Cherezov, V., Rosenbaum, D.M., Hanson, M.A., Rasmussen, S.G.F., Thian, F.S., Kobilka, T.S., Choi, H.J., Kuhn, P., Weis, W.I., Kobilka, B.K., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
登録日2007-10-05
公開日2007-10-30
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.
Science, 318, 2007
2VDF
  • Download 2vdf
  • View 2vdf
Molmil generated image of 2vdf
STRUCTURE OF THE OPCA ADHESION FROM NEISSERIA MENINGITIDIS DETERMINED BY CRYSTALLIZATION FROM THE CUBIC MESOPHASE
分子名称:OUTER MEMBRANE PROTEIN, N-OCTANE, SULFATE ION
著者Cherezov, V., Liu, W., Derrick, J.P., Luan, B., Aksimentiev, A., Katritch, V., Caffrey, M.
登録日2007-10-05
公開日2007-10-23
最終更新日2019-09-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin.
Proteins, 71, 2008
3BYP
  • Download 3byp
  • View 3byp
Molmil generated image of 3byp
MODE OF ACTION OF A PUTATIVE ZINC TRANSPORTER CZRB
分子名称:CzrB protein, SULFATE ION
著者Cherezov, V., Srinivasan, V., Szebenyi, D.M.E., Caffrey, M.
登録日2008-01-16
公開日2008-09-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Insights into the Mode of Action of a Putative Zinc Transporter CzrB in Thermus thermophilus
Structure, 16, 2008
3BYR
  • Download 3byr
  • View 3byr
Molmil generated image of 3byr
MODE OF ACTION OF A PUTATIVE ZINC TRANSPORTER CZRB (ZN FORM)
分子名称:CzrB protein, ZINC ION
著者Cherezov, V., Srinivasan, V., Szebenyi, D.M.E., Caffrey, M.
登録日2008-01-16
公開日2008-09-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insights into the Mode of Action of a Putative Zinc Transporter CzrB in Thermus thermophilus
Structure, 16, 2008
2FKW
  • Download 2fkw
  • View 2fkw
Molmil generated image of 2fkw
STRUCTURE OF LH2 FROM RPS. ACIDOPHILA CRYSTALLIZED IN LIPIDIC MESOPHASES
分子名称:Light-harvesting protein B-800/850, alpha chain, beta chain, ...
著者Papiz, M.Z., Cherezov, V., Clogston, J., Caffrey, M.
登録日2006-01-05
公開日2006-03-28
最終更新日2016-03-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Room to Move: Crystallizing Membrane Proteins in Swollen Lipidic Mesophases
J.Mol.Biol., 357, 2006
2GUF
  • Download 2guf
  • View 2guf
Molmil generated image of 2guf
IN MESO CRYSTAL STRUCTURE OF THE COBALAMIN TRANSPORTER, BTUB
分子名称:Vitamin B12 transporter btuB, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate, FORMIC ACID, ...
著者Caffrey, M., Cherezov, V., Yamashita, E., Cramer, W.A.
登録日2006-04-29
公開日2006-12-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献In Meso Structure of the Cobalamin Transporter, BtuB, at 1.95 A Resolution.
J.Mol.Biol., 364, 2006
5JTB
  • Download 5jtb
  • View 5jtb
Molmil generated image of 5jtb
CRYSTAL STRUCTURE OF THE CHIMERIC PROTEIN OF A2AAR-BRIL WITH BOUND IODIDE IONS
分子名称:Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, CHOLESTEROL, ...
著者Melnikov, I., Polovinkin, V., Shevtsov, M., Borshchevskiy, V., Cherezov, V., Popov, A., Gordeliy, V.
登録日2016-05-09
公開日2017-05-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Fast iodide-SAD phasing for high-throughput membrane protein structure determination.
Sci Adv, 3, 2017
6RZ4
  • Download 6rz4
  • View 6rz4
Molmil generated image of 6rz4
CRYSTAL STRUCTURE OF CYSTEINYL LEUKOTRIENE RECEPTOR 1 IN COMPLEX WITH PRANLUKAST
分子名称:Cysteinyl leukotriene receptor 1,Soluble cytochrome b562,Cysteinyl leukotriene receptor 1, pranlukast, SODIUM ION, ...
著者Luginina, A., Gusach, A., Marin, E., Mishin, A., Brouillette, R., Popov, P., Shiryaeva, A., Besserer-Offroy, E., Longpre, J.M., Lyapina, E., Ishchenko, A., Patel, N., Polovinkin, V., Safronova, N., Bogorodskiy, A., Edelweiss, E., Liu, W., Batyuk, A., Gordeliy, V., Han, G.W., Sarret, P., Katritch, V., Borshchevskiy, V., Cherezov, V.
登録日2019-06-12
公開日2019-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs.
Sci Adv, 5, 2019
6RZ5
  • Download 6rz5
  • View 6rz5
Molmil generated image of 6rz5
XFEL CRYSTAL STRUCTURE OF THE HUMAN CYSTEINYL LEUKOTRIENE RECEPTOR 1 IN COMPLEX WITH ZAFIRLUKAST
分子名称:Cysteinyl leukotriene receptor 1,Soluble cytochrome b562,Cysteinyl leukotriene receptor 1, zafirlukast, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ...
著者Luginina, A., Gusach, A., Marin, E., Mishin, A., Brouillette, R., Popov, P., Shiryaeva, A., Besserer-Offroy, E., Longpre, J.M., Lyapina, E., Ishchenko, A., Patel, N., Polovinkin, V., Safronova, N., Bogorodskiy, A., Edelweiss, E., Liu, W., Batyuk, A., Gordeliy, V., Han, G.W., Sarret, P., Katritch, V., Borshchevskiy, V., Cherezov, V.
登録日2019-06-12
公開日2019-10-30
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs.
Sci Adv, 5, 2019
3NY8
  • Download 3ny8
  • View 3ny8
Molmil generated image of 3ny8
CRYSTAL STRUCTURE OF THE HUMAN BETA2 ADRENERGIC RECEPTOR IN COMPLEX WITH THE INVERSE AGONIST ICI 118,551
分子名称:Beta-2 adrenergic receptor, Lysozyme, CHOLESTEROL, ...
著者Wacker, D., Fenalti, G., Brown, M.A., Katritch, V., Abagyan, R., Cherezov, V., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
登録日2010-07-14
公開日2010-08-11
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Conserved Binding Mode of Human beta(2) Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography
J.Am.Chem.Soc., 132, 2010
3NY9
  • Download 3ny9
  • View 3ny9
Molmil generated image of 3ny9
CRYSTAL STRUCTURE OF THE HUMAN BETA2 ADRENERGIC RECEPTOR IN COMPLEX WITH A NOVEL INVERSE AGONIST
分子名称:Beta-2 adrenergic receptor, Lysozyme, CHOLESTEROL, ...
著者Fenalti, G., Wacker, D., Brown, M.A., Katritch, V., Abagyan, R., Cherezov, V., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
登録日2010-07-14
公開日2010-08-11
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Conserved Binding Mode of Human beta(2) Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography
J.Am.Chem.Soc., 132, 2010
3NYA
  • Download 3nya
  • View 3nya
Molmil generated image of 3nya
CRYSTAL STRUCTURE OF THE HUMAN BETA2 ADRENERGIC RECEPTOR IN COMPLEX WITH THE NEUTRAL ANTAGONIST ALPRENOLOL
分子名称:Beta-2 adrenergic receptor, Lysozyme, CHOLESTEROL, ...
著者Brown, M.A., Wacker, D., Fenalti, G., Katritch, V., Abagyan, R., Cherezov, V., Stevens, R.C., GPCR Network (GPCR)
登録日2010-07-14
公開日2010-08-11
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Conserved Binding Mode of Human beta(2) Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography
J.Am.Chem.Soc., 132, 2010
3ODU
  • Download 3odu
  • View 3odu
Molmil generated image of 3odu
THE 2.5 A STRUCTURE OF THE CXCR4 CHEMOKINE RECEPTOR IN COMPLEX WITH SMALL MOLECULE ANTAGONIST IT1T
分子名称:C-X-C chemokine receptor type 4, Lysozyme Chimera, (6,6-dimethyl-5,6-dihydroimidazo[2,1-b][1,3]thiazol-3-yl)methyl N,N'-dicyclohexylimidothiocarbamate, ...
著者Wu, B., Mol, C.D., Han, G.W., Katritch, V., Chien, E.Y.T., Liu, W., Cherezov, V., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
登録日2010-08-11
公開日2010-10-27
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists.
Science, 330, 2010
3OE0
  • Download 3oe0
  • View 3oe0
Molmil generated image of 3oe0
CRYSTAL STRUCTURE OF THE CXCR4 CHEMOKINE RECEPTOR IN COMPLEX WITH A CYCLIC PEPTIDE ANTAGONIST CVX15
分子名称:C-X-C chemokine receptor type 4, Lysozyme Chimera, Polyphemusin analog, ...
著者Wu, B., Mol, C.D., Han, G.W., Katritch, V., Chien, E.Y.T., Liu, W., Cherezov, V., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
登録日2010-08-12
公開日2010-10-27
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists.
Science, 330, 2010
3OE6
  • Download 3oe6
  • View 3oe6
Molmil generated image of 3oe6
CRYSTAL STRUCTURE OF THE CXCR4 CHEMOKINE RECEPTOR IN COMPLEX WITH A SMALL MOLECULE ANTAGONIST IT1T IN I222 SPACEGROUP
分子名称:C-X-C chemokine receptor type 4, Lysozyme Chimera, (6,6-dimethyl-5,6-dihydroimidazo[2,1-b][1,3]thiazol-3-yl)methyl N,N'-dicyclohexylimidothiocarbamate, ...
著者Wu, B., Mol, C.D., Han, G.W., Katritch, V., Chien, E.Y.T., Liu, W., Cherezov, V., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
登録日2010-08-12
公開日2010-10-27
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists.
Science, 330, 2010
3OE8
  • Download 3oe8
  • View 3oe8
Molmil generated image of 3oe8
CRYSTAL STRUCTURE OF THE CXCR4 CHEMOKINE RECEPTOR IN COMPLEX WITH A SMALL MOLECULE ANTAGONIST IT1T IN P1 SPACEGROUP
分子名称:C-X-C chemokine receptor type 4, Lysozyme Chimera, (6,6-dimethyl-5,6-dihydroimidazo[2,1-b][1,3]thiazol-3-yl)methyl N,N'-dicyclohexylimidothiocarbamate
著者Wu, B., Mol, C.D., Han, G.W., Katritch, V., Chien, E.Y.T., Liu, W., Cherezov, V., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
登録日2010-08-12
公開日2010-10-27
最終更新日2018-06-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists.
Science, 330, 2010
3OE9
  • Download 3oe9
  • View 3oe9
Molmil generated image of 3oe9
CRYSTAL STRUCTURE OF THE CHEMOKINE CXCR4 RECEPTOR IN COMPLEX WITH A SMALL MOLECULE ANTAGONIST IT1T IN P1 SPACEGROUP
分子名称:C-X-C chemokine receptor type 4, Lysozyme Chimera, (6,6-dimethyl-5,6-dihydroimidazo[2,1-b][1,3]thiazol-3-yl)methyl N,N'-dicyclohexylimidothiocarbamate
著者Wu, B., Mol, C.D., Han, G.W., Katritch, V., Chien, E.Y.T., Liu, W., Cherezov, V., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
登録日2010-08-12
公開日2010-10-27
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists.
Science, 330, 2010
3PBL
  • Download 3pbl
  • View 3pbl
Molmil generated image of 3pbl
STRUCTURE OF THE HUMAN DOPAMINE D3 RECEPTOR IN COMPLEX WITH ETICLOPRIDE
分子名称:D(3) dopamine receptor, Lysozyme chimera, 3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide, ...
著者Chien, E.Y.T., Liu, W., Han, G.W., Katritch, V., Zhao, Q., Cherezov, V., Stevens, R.C., Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
登録日2010-10-20
公開日2010-11-03
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Structure of the human dopamine d3 receptor in complex with a d2/d3 selective antagonist.
Science, 330, 2010
3QAK
  • Download 3qak
  • View 3qak
Molmil generated image of 3qak
AGONIST BOUND STRUCTURE OF THE HUMAN ADENOSINE A2A RECEPTOR
分子名称:Adenosine receptor A2a,lysozyme chimera, 6-(2,2-diphenylethylamino)-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-oxolan-2-yl]-N-[2-[(1-pyridin-2-ylpiperidin-4-yl)carbamoylamino]ethyl]purine-2-carboxamide, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
著者Xu, F., Wu, H., Katritch, V., Han, G.W., Cherezov, V., Stevens, R., GPCR Network (GPCR)
登録日2011-01-11
公開日2011-03-09
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structure of an agonist-bound human A2A adenosine receptor.
Science, 332, 2011
3RZE
  • Download 3rze
  • View 3rze
Molmil generated image of 3rze
STRUCTURE OF THE HUMAN HISTAMINE H1 RECEPTOR IN COMPLEX WITH DOXEPIN
分子名称:Histamine H1 receptor, Lysozyme chimera, (3E)-3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine, ...
著者Shimamura, T., Han, G.W., Shiroishi, M., Weyand, S., Tsujimoto, H., Winter, G., Katritch, V., Abagyan, R., Cherezov, V., Liu, W., Kobayashi, T., Stevens, R., Iwata, S., GPCR Network (GPCR)
登録日2011-05-11
公開日2011-06-15
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the human histamine H1 receptor complex with doxepin.
Nature, 475, 2011
3S8F
  • Download 3s8f
  • View 3s8f
Molmil generated image of 3s8f
1.8 A STRUCTURE OF BA3 CYTOCHROME C OXIDASE FROM THERMUS THERMOPHILUS IN LIPID ENVIRONMENT
分子名称:Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide 2A, ...
著者Tiefenbrunn, T., Liu, W., Chen, Y., Katritch, V., Stout, C.D., Fee, J.A., Cherezov, V.
登録日2011-05-27
公開日2011-08-03
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High resolution structure of the ba3 cytochrome c oxidase from Thermus thermophilus in a lipidic environment.
Plos One, 6, 2011
3S8G
  • Download 3s8g
  • View 3s8g
Molmil generated image of 3s8g
1.8 A STRUCTURE OF BA3 CYTOCHROME C OXIDASE MUTANT (A120F) FROM THERMUS THERMOPHILUS IN LIPID ENVIRONMENT
分子名称:Cytochrome c oxidase subunit 1, Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide 2A, ...
著者Tiefenbrunn, T., Liu, W., Chen, Y., Katritch, V., Stout, C.D., Fee, J.A., Cherezov, V.
登録日2011-05-27
公開日2011-08-03
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High resolution structure of the ba3 cytochrome c oxidase from Thermus thermophilus in a lipidic environment.
Plos One, 6, 2011
4DJH
  • Download 4djh
  • View 4djh
Molmil generated image of 4djh
STRUCTURE OF THE HUMAN KAPPA OPIOID RECEPTOR IN COMPLEX WITH JDTIC
分子名称:Kappa-type opioid receptor, Lysozyme, (3R)-7-hydroxy-N-{(2S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]-3-methylbutan-2-yl}-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, ...
著者Wu, H., Wacker, D., Katritch, V., Mileni, M., Han, G.W., Vardy, E., Liu, W., Thompson, A.A., Huang, X.P., Carroll, F.I., Mascarella, S.W., Westkaemper, R.B., Mosier, P.D., Roth, B.L., Cherezov, V., Stevens, R.C., GPCR Network (GPCR)
登録日2012-02-01
公開日2012-03-21
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献tructure of the human kappa-opioid receptor in complex with JDTic
Nature, 485, 2012
4EA3
  • Download 4ea3
  • View 4ea3
Molmil generated image of 4ea3
STRUCTURE OF THE N/OFQ OPIOID RECEPTOR IN COMPLEX WITH A PEPTIDE MIMETIC
分子名称:Fusion protein of Nociceptin receptor and cytochrome b562, 1-benzyl-N-[3-(1'H,3H-spiro[2-benzofuran-1,4'-piperidin]-1'-yl)propyl]-D-prolinamide, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ...
著者Thompson, A.A., Liu, W., Chun, E., Katritch, V., Wu, H., Vardy, E., Huang, X.P., Trapella, C., Guerrini, R., Calo, G., Roth, B.L., Cherezov, V., Stevens, R.C., GPCR Network (GPCR)
登録日2012-03-22
公開日2012-04-25
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3.013 Å)
主引用文献Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic.
Nature, 485, 2012
4EIY
  • Download 4eiy
  • View 4eiy
Molmil generated image of 4eiy
CRYSTAL STRUCTURE OF THE CHIMERIC PROTEIN OF A2AAR-BRIL IN COMPLEX WITH ZM241385 AT 1.8A RESOLUTION
分子名称:Adenosine receptor A2a/Soluble cytochrome b562 chimera, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, SODIUM ION, ...
著者Liu, W., Chun, E., Thompson, A.A., Chubukov, P., Xu, F., Katritch, V., Han, G.W., Heitman, L.H., Ijzerman, A.P., Cherezov, V., Stevens, R.C., GPCR Network (GPCR)
登録日2012-04-06
公開日2012-07-25
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for allosteric regulation of GPCRs by sodium ions.
Science, 337, 2012