7EB6
 
 | | Crystal structure of GTP-binding protein-like domain of AGAP1 | | Descriptor: | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 | | Authors: | Cheng, N, Zhang, H, Zhang, S, Ma, X, Meng, G. | | Deposit date: | 2021-03-09 | | Release date: | 2021-04-21 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.014 Å) | | Cite: | Crystal structure of the GTP-binding protein-like domain of AGAP1.
Acta Crystallogr.,Sect.F, 77, 2021
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1IF0
 | | PSEUDO-ATOMIC MODEL OF BACTERIOPHAGE HK97 PROCAPSID (PROHEAD II) | | Descriptor: | PROTEIN (MAJOR CAPSID PROTEIN GP5) | | Authors: | Conway, J.F, Wikoff, W.R, Cheng, N, Duda, R.L, Hendrix, R.W, Johnson, J.E, Steven, A.C. | | Deposit date: | 2001-04-11 | | Release date: | 2001-05-02 | | Last modified: | 2024-02-07 | | Method: | ELECTRON MICROSCOPY (12 Å) | | Cite: | Virus maturation involving large subunit rotations and local refolding.
Science, 292, 2001
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2FTE
 | | Bacteriophage HK97 Expansion Intermediate IV | | Descriptor: | major capsid protein | | Authors: | Gan, L, Speir, J.A, Conway, J.F, Lander, G, Cheng, N, Firek, B.A, Hendrix, R.W, Duda, R.L, Liljas, L, Johnson, J.E. | | Deposit date: | 2006-01-24 | | Release date: | 2006-02-07 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY | | Cite: | Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM.
Structure, 14, 2006
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6UI7
 | | HBV T=4 149C3A | | Descriptor: | Core protein | | Authors: | Wu, W, Watts, N.R, Cheng, N, Huang, R, Steven, A, Wingfield, P.T. | | Deposit date: | 2019-09-30 | | Release date: | 2019-11-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Expression of quasi-equivalence and capsid dimorphism in the Hepadnaviridae.
Plos Comput.Biol., 16, 2020
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6UI6
 | | HBV T=3 149C3A | | Descriptor: | Core protein | | Authors: | Wu, W, Watts, N.R, Cheng, N, Huang, R, Steven, A, Wingfield, P.T. | | Deposit date: | 2019-09-30 | | Release date: | 2019-11-06 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.53 Å) | | Cite: | Expression of quasi-equivalence and capsid dimorphism in the Hepadnaviridae.
Plos Comput.Biol., 16, 2020
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1XYR
 | | Poliovirus 135S cell entry intermediate | | Descriptor: | Genome polyprotein, Coat protein VP1, Coat protein VP2, ... | | Authors: | Bubeck, D, Filman, D.J, Cheng, N, Steven, A.C, Hogle, J.M, Belnap, D.M. | | Deposit date: | 2004-11-10 | | Release date: | 2005-08-02 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (11 Å) | | Cite: | The structure of the poliovirus 135S cell entry intermediate at 10-angstrom resolution reveals the location of an externalized polypeptide that binds to membranes.
J.Virol., 79, 2005
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2FSY
 | | Bacteriophage HK97 Pepsin-treated Expansion Intermediate IV | | Descriptor: | major capsid protein | | Authors: | Gan, L, Speir, J.A, Conway, J.F, Lander, G, Cheng, N, Firek, B.A, Hendrix, R.W, Duda, R.L, Liljas, L, Johnson, J.E. | | Deposit date: | 2006-01-23 | | Release date: | 2006-02-07 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM.
Structure, 14, 2006
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2FRP
 | | Bacteriophage HK97 Expansion Intermediate IV | | Descriptor: | Major capsid protein | | Authors: | Gan, L, Speir, J.A, Conway, J.F, Lander, G, Cheng, N, Firek, B.A, Hendrix, R.W, Duda, R.L, Liljas, L, Johnson, J.E. | | Deposit date: | 2006-01-19 | | Release date: | 2006-02-07 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (7.5 Å) | | Cite: | Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM.
Structure, 14, 2006
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2FT1
 | | Bacteriophage HK97 Head II | | Descriptor: | major capsid protein | | Authors: | Gan, L, Speir, J.A, Conway, J.F, Lander, G, Cheng, N, Firek, B.A, Hendrix, R.W, Duda, R.L, Liljas, L, Johnson, J.E. | | Deposit date: | 2006-01-23 | | Release date: | 2006-02-07 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.9 Å) | | Cite: | Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM.
Structure, 14, 2006
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2FS3
 | | Bacteriophage HK97 K169Y Head I | | Descriptor: | Major capsid protein | | Authors: | Gan, L, Speir, J.A, Conway, J.F, Lander, G, Cheng, N, Firek, B.A, Hendrix, R.W, Duda, R.L, Liljas, L, Johnson, J.E. | | Deposit date: | 2006-01-20 | | Release date: | 2006-02-07 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (4.2 Å) | | Cite: | Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM.
Structure, 14, 2006
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4BTQ
 | | Coordinates of the bacteriophage phi6 capsid subunits fitted into the cryoEM map EMD-1206 | | Descriptor: | MAJOR INNER PROTEIN P1 | | Authors: | Nemecek, D, Boura, E, Wu, W, Cheng, N, Plevka, P, Qiao, J, Mindich, L, Heymann, J.B, Hurley, J.H, Steven, A.C. | | Deposit date: | 2013-06-18 | | Release date: | 2013-12-11 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (7.5 Å) | | Cite: | Subunit Folds and Maturation Pathway of a Dsrna Virus Capsid.
Structure, 21, 2013
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4BTG
 | | Coordinates of the bacteriophage phi6 capsid subunits (P1A and P1B) fitted into the cryoEM reconstruction of the procapsid at 4.4 A resolution | | Descriptor: | MAJOR INNER PROTEIN P1 | | Authors: | Nemecek, D, Boura, E, Wu, W, Cheng, N, Plevka, P, Qiao, J, Mindich, L, Heymann, J.B, Hurley, J.H, Steven, A.C. | | Deposit date: | 2013-06-17 | | Release date: | 2013-08-14 | | Last modified: | 2017-08-23 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Subunit Folds and Maturation Pathway of a Dsrna Virus Capsid.
Structure, 21, 2013
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7DW5
 | | Crystal structure of DUX4 HD1-HD2 domain complexed with ERG sites | | Descriptor: | BROMIDE ION, DNA (5'-D(P*CP*GP*AP*CP*TP*TP*GP*AP*TP*GP*AP*GP*AP*TP*TP*AP*GP*AP*CP*TP*G)-3'), Double homeobox protein 4-like protein 2 | | Authors: | Zhang, H, Cheng, N, Li, Z, Zhang, W, Dong, X, Huang, J, Meng, G. | | Deposit date: | 2021-01-15 | | Release date: | 2021-11-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.83 Å) | | Cite: | DNA crosslinking and recombination-activating genes 1/2 (RAG1/2) are required for oncogenic splicing in acute lymphoblastic leukemia.
Cancer Commun (Lond), 41, 2021
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6A8R
 | | Crystal structure of DUX4 HD2 domain associated with ERG DNA binding site | | Descriptor: | DNA (5'-D(P*AP*AP*TP*CP*TP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*TP*GP*AP*TP*GP*AP*GP*AP*TP*T)-3'), Double homeobox protein 4 | | Authors: | Dong, X, Zhang, H, Cheng, N, Meng, G. | | Deposit date: | 2018-07-10 | | Release date: | 2018-10-24 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | DUX4HD2-DNAERGstructure reveals new insight into DUX4-Responsive-Element.
Leukemia, 33, 2019
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6I9E
 | | Thermophage P23-45 empty expanded capsid | | Descriptor: | Auxiliary protein, Major head protein | | Authors: | Bayfield, O.W, Klimuk, E, Winkler, D.C, Hesketh, E.L, Chechik, M, Cheng, N, Dykeman, E.C, Minakhin, L, Ranson, N.A, Severinov, K, Steven, A.C, Antson, A.A. | | Deposit date: | 2018-11-23 | | Release date: | 2019-02-06 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (3.74 Å) | | Cite: | Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6IBC
 | | Thermophage P23-45 procapsid | | Descriptor: | Major head protein | | Authors: | Bayfield, O.W, Klimuk, E, Winkler, D.C, Hesketh, E.L, Chechik, M, Cheng, N, Dykeman, E.C, Minakhin, L, Ranson, N.A, Severinov, K, Steven, A.C, Antson, A.A. | | Deposit date: | 2018-11-29 | | Release date: | 2019-02-13 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (4.39 Å) | | Cite: | Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6IMQ
 | | Crystal structure of PML B1-box multimers | | Descriptor: | CHLORIDE ION, Protein PML, ZINC ION | | Authors: | Li, Y, Ma, X, Chen, Z, Wu, H, Wang, P, Wu, W, Cheng, N, Zeng, L, Zhang, H, Cai, X, Chen, S.J, Chen, Z, Meng, G. | | Deposit date: | 2018-10-23 | | Release date: | 2019-07-31 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis.
Nat Commun, 10, 2019
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6IBG
 | | Bacteriophage G20c portal protein crystal structure for construct with intact N-terminus | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Portal protein | | Authors: | Bayfield, O.W, Klimuk, E, Winkler, D.C, Hesketh, E.L, Chechik, M, Cheng, N, Dykeman, E.C, Minakhin, L, Ranson, N.A, Severinov, K, Steven, A.C, Antson, A.A. | | Deposit date: | 2018-11-30 | | Release date: | 2019-01-23 | | Last modified: | 2022-03-30 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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3IPZ
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3J6R
 | | Electron cryo-microscopy of Human Papillomavirus Type 16 capsid | | Descriptor: | Major capsid protein L1 | | Authors: | Cardone, G, Moyer, A.L, Cheng, N, Thompson, C.D, Dvoretzky, I, Lowy, D.R, Schiller, J.T, Steven, A.C, Buck, C.B, Trus, B.L. | | Deposit date: | 2014-03-20 | | Release date: | 2014-07-23 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (9.1 Å) | | Cite: | Maturation of the human papillomavirus 16 capsid.
MBio, 5, 2014
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3J3P
 | | Conformational Shift of a Major Poliovirus Antigen Confirmed by Immuno-Cryogenic Electron Microscopy: 135S Poliovirus and C3-Fab Complex | | Descriptor: | C3 antibody, heavy chain, light chain, ... | | Authors: | Lin, J, Cheng, N, Hogle, J.M, Steven, A.C, Belnap, D.M. | | Deposit date: | 2013-04-10 | | Release date: | 2013-07-03 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (9.1 Å) | | Cite: | Conformational shift of a major poliovirus antigen confirmed by immuno-cryogenic electron microscopy.
J.Immunol., 191, 2013
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3J8F
 | | Cryo-EM reconstruction of poliovirus-receptor complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein VP1, ... | | Authors: | Strauss, M, Filman, D.J, Belnap, D.M, Cheng, N, Noel, R.T, Hogle, J.M. | | Deposit date: | 2014-10-20 | | Release date: | 2015-02-11 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Nectin-Like Interactions between Poliovirus and Its Receptor Trigger Conformational Changes Associated with Cell Entry.
J.Virol., 89, 2015
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3J3O
 | | Conformational Shift of a Major Poliovirus Antigen Confirmed by Immuno-Cryogenic Electron Microscopy: 160S Poliovirus and C3-Fab Complex | | Descriptor: | C3 antibody, heavy chain, light chain, ... | | Authors: | Lin, J, Cheng, N, Hogle, J.M, Steven, A.C, Belnap, D.M. | | Deposit date: | 2013-04-10 | | Release date: | 2013-07-03 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (11.1 Å) | | Cite: | Conformational shift of a major poliovirus antigen confirmed by immuno-cryogenic electron microscopy.
J.Immunol., 191, 2013
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3J9F
 | | Poliovirus complexed with soluble, deglycosylated poliovirus receptor (Pvr) at 4 degrees C | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ... | | Authors: | Strauss, M, Filman, D.J, Belnap, D.M, Cheng, N, Noel, R.T, Hogle, J.M. | | Deposit date: | 2015-01-15 | | Release date: | 2015-02-11 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Nectin-Like Interactions between Poliovirus and Its Receptor Trigger Conformational Changes Associated with Cell Entry.
J.Virol., 89, 2015
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4WUU
 | | Structure of ESK1 in complex with HLA-A*0201/WT1 | | Descriptor: | ARG-MET-PHE-PRO-ASN-ALA-PRO-TYR-LEU, Beta-2-microglobulin, ESK1, ... | | Authors: | Ataie, N.J, Ng, H.L. | | Deposit date: | 2014-11-03 | | Release date: | 2015-12-30 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.047 Å) | | Cite: | Structure of a TCR-Mimic Antibody with Target Predicts Pharmacogenetics.
J.Mol.Biol., 428, 2016
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