Author results

4HJE
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CRYSTAL STRUCTURE OF P53 CORE DOMAIN IN COMPLEX WITH DNA
分子名称:Cellular tumor antigen p53, DNA (5'-D(*TP*CP*AP*CP*AP*AP*GP*TP*TP*AP*GP*AP*GP*AP*CP*AP*AP*GP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*CP*TP*TP*GP*TP*CP*TP*CP*TP*AP*AP*CP*TP*TP*GP*TP*GP*A)-3'), ...
著者Chen, Y., Chen, L.
登録日2012-10-12
公開日2013-07-17
最終更新日2013-10-09
実験手法X-RAY DIFFRACTION (1.907 Å)
主引用文献Structure of p53 binding to the BAX response element reveals DNA unwinding and compression to accommodate base-pair insertion.
Nucleic Acids Res., 41, 2013
4HC7
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CRYSTAL STRUCTURE OF THE FULL DNA BINDING DOMAIN OF GATA3-COMPLEX 2
分子名称:Trans-acting T-cell-specific transcription factor GATA-3, DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), ...
著者Chen, Y., Bates, D.L., Dey, R., Chen, L.
登録日2012-09-28
公開日2012-12-05
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
4HC9
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DNA BINDING BY GATA TRANSCRIPTION FACTOR-COMPLEX 3
分子名称:Trans-acting T-cell-specific transcription factor GATA-3, DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), ...
著者Chen, Y., Bates, D.L., Dey, R., Chen, L.
登録日2012-09-28
公開日2012-12-05
最終更新日2014-12-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
4HCA
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DNA BINDING BY GATA TRANSCRIPTION FACTOR-COMPLEX 1
分子名称:Trans-acting T-cell-specific transcription factor GATA-3, DNA (5'-D(*AP*AP*TP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*A)-3'), ...
著者Chen, Y., Bates, D.L., Dey, R., Chen, L.
登録日2012-09-28
公開日2012-12-05
最終更新日2013-01-02
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
4WK8
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FOXP3 FORMS A DOMAIN-SWAPPED DIMER TO BRIDGE DNA
分子名称:DNA (5'-D(*TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*G)-3'), DNA (5'-D(*AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*T)-3'), Forkhead box protein P3
著者Chen, Y., Chen, L.
登録日2014-10-01
公開日2015-01-21
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (3.4006 Å)
主引用文献DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions.
Nucleic Acids Res., 43, 2015
1J48
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CRYSTAL STRUCTURE OF APO-C1027
分子名称:Apoprotein of C1027
著者Chen, Y., Li, J., Liu, Y., Bartlam, M., Gao, Y., Jin, L., Tang, H., Shao, Y., Zhen, Y., Rao, Z.
登録日2001-07-30
公開日2003-06-03
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Apo-C1027 and Computer Modeling Analysis of C1027 Chromophore- Protein Complex
To be published
3KMD
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CRYSTAL STRUCTURE OF THE P53 CORE DOMAIN BOUND TO A FULL CONSENSUS SITE AS A SELF-ASSEMBLED TETRAMER
分子名称:Cellular tumor antigen p53, 5'-D(*GP*GP*GP*CP*AP*TP*GP*CP*CP*TP*AP*GP*GP*CP*AP*TP*GP*CP*C)-3', ZINC ION
著者Chen, Y., Dey, R., Chen, L.
登録日2009-11-10
公開日2010-02-23
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer.
Structure, 18, 2010
5GTD
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O-SUCCINYLBENZOATE COA SYNTHETASE (MENE) FROM BACILLUS SUBTILIS IN COMPLEX WITH THE ACYL-ADENYLATE INTERMEDIATE OSB-AMP
分子名称:2-succinylbenzoate--CoA ligase, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Chen, Y., Guo, Z.
登録日2016-08-20
公開日2017-01-04
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Mechanistic Insights from the Crystal Structure of Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase Complexed with the Adenylate Intermediate
Biochemistry, 55, 2016
3RSN
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CRYSTAL STRUCTURE OF THE N-TERMINAL REGION OF HUMAN ASH2L
分子名称:Set1/Ash2 histone methyltransferase complex subunit ASH2, ZINC ION
著者Chen, Y., Wan, B., Wang, K.C., Cao, F., Yang, Y., Protacio, A., Dou, Y., Chang, H.Y., Lei, M.
登録日2011-05-02
公開日2011-06-22
最終更新日2011-12-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding.
Embo Rep., 12, 2011
1CZ8
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VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH AN AFFINITY MATURED ANTIBODY
分子名称:Vascular endothelial growth factor A, LIGHT CHAIN OF NEUTRALIZING ANTIBODY, HEAVY CHAIN OF NEUTRALIZING ANTIBODY, ...
著者Chen, Y., Wiesmann, C., Fuh, G., Li, B., Christinger, H.W., McKay, P., de Vos, A.M., Lowman, H.B.
登録日1999-09-01
公開日2000-03-20
最終更新日2017-04-05
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen.
J.Mol.Biol., 293, 1999
2HKO
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CRYSTAL STRUCTURE OF LSD1
分子名称:Lysine-specific histone demethylase 1, FLAVIN-ADENINE DINUCLEOTIDE
著者Chen, Y., Yang, Y.T., Wang, F., Yanane, K., Zhang, Y., Lei, M.
登録日2006-07-05
公開日2006-08-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of human histone lysine-specific demethylase 1 (LSD1).
Proc.Natl.Acad.Sci.Usa, 103, 2006
3OWT
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CRYSTAL STRUCTURE OF S. CEREVISIAE RAP1-SIR3 COMPLEX
分子名称:DNA-binding protein RAP1, Regulatory protein SIR3
著者Chen, Y., Yang, Y., Lei, M.
登録日2010-09-20
公開日2011-01-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms.
Nat.Struct.Mol.Biol., 18, 2011
3BQO
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CRYSTAL STRUCTURE OF TRF1 TRFH DOMAIN AND TIN2 PEPTIDE COMPLEX
分子名称:Telomeric repeat-binding factor 1, TERF1-interacting nuclear factor 2
著者Chen, Y., Yang, Y., van Overbeek, M., Donigian, J.R., Baciu, P., de Lange, T., Lei, M.
登録日2007-12-20
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
3BU8
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CRYSTAL STRUCTURE OF TRF2 TRFH DOMAIN AND TIN2 PEPTIDE COMPLEX
分子名称:Telomeric repeat-binding factor 2, TERF1-interacting nuclear factor 2
著者Chen, Y., Yang, Y., van Overbeek, M., Donigian, J.R., Baciu, P., de Lange, T., Lei, M.
登録日2008-01-02
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
3BUA
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CRYSTAL STRUCTURE OF TRF2 TRFH DOMAIN AND APOLLO PEPTIDE COMPLEX
分子名称:Telomeric repeat-binding factor 2, DNA cross-link repair 1B protein
著者Chen, Y., Yang, Y., van Overbeek, M., Donigian, J.R., Baciu, P., de Lange, T., Lei, M.
登録日2008-01-02
公開日2008-02-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
3K6G
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CRYSTAL STRUCTURE OF RAP1 AND TRF2 COMPLEX
分子名称:Telomeric repeat-binding factor 2-interacting protein 1, Telomeric repeat-binding factor 2
著者Chen, Y., Rai, R., Yang, Y.T., Zheng, H., Chang, S., Lei, M.
登録日2009-10-08
公開日2010-10-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms.
Nat.Struct.Mol.Biol., 18, 2011
3TOJ
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STRUCTURE OF THE SPRY DOMAIN OF HUMAN ASH2L
分子名称:Set1/Ash2 histone methyltransferase complex subunit ASH2
著者Chen, Y., Cao, F., Wan, B., Dou, Y., Lei, M.
登録日2011-09-05
公開日2012-01-25
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30.
Cell Res., 22, 2012
4IK1
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HIGH RESOLUTION STRUCTURE OF GCAMPJ AT PH 8.5
分子名称:RCaMP, Green fluorescent protein, CALCIUM ION
著者Chen, Y., Song, X., Miao, L., Zhu, Y., Ji, G.
登録日2012-12-25
公開日2014-02-05
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
4IK3
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HIGH RESOLUTION STRUCTURE OF GCAMP3 AT PH 8.5
分子名称:RCaMP, Green fluorescent protein, CALCIUM ION
著者Chen, Y., Song, X., Miao, L., Zhu, Y., Ji, G.
登録日2012-12-25
公開日2014-01-29
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (2.007 Å)
主引用文献Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
4IK4
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HIGH RESOLUTION STRUCTURE OF GCAMP3 AT PH 5.0
分子名称:RCaMP, Green fluorescent protein, CALCIUM ION
著者Chen, Y., Song, X., Miao, L., Zhu, Y., Ji, G.
登録日2012-12-25
公開日2014-02-05
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
4IK5
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HIGH RESOLUTION STRUCTURE OF DELTA-REST-GCAMP3
分子名称:RCaMP, Green fluorescent protein, CALCIUM ION
著者Chen, Y., Song, X., Miao, L., Zhu, Y., Ji, G.
登録日2012-12-25
公開日2014-01-29
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
4IK8
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HIGH RESOLUTION STRUCTURE OF GCAMP3 DIMER FORM 1 AT PH 7.5
分子名称:RCaMP, Green fluorescent protein, CALCIUM ION
著者Chen, Y., Song, X., Miao, L., Zhu, Y., Ji, G.
登録日2012-12-25
公開日2014-02-05
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
4IK9
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HIGH RESOLUTION STRUCTURE OF GCAMP3 DIMER FORM 2 AT PH 7.5
分子名称:RCaMP, Green fluorescent protein, CALCIUM ION, ...
著者Chen, Y., Song, X., Miao, L., Zhu, Y., Ji, G.
登録日2012-12-25
公開日2014-01-29
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
4L3N
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CRYSTAL STRUCTURE OF THE RECEPTOR-BINDING DOMAIN FROM NEWLY EMERGED MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS
分子名称:S protein, 1,2-ETHANEDIOL, N-ACETYL-D-GLUCOSAMINE
著者Chen, Y., Rajashankar, K.R., Yang, Y., Agnihothram, S.S., Liu, C., Lin, Y.-L., Baric, R.S., Li, F.
登録日2013-06-06
公開日2013-07-31
最終更新日2013-09-25
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Crystal structure of the receptor-binding domain from newly emerged middle East respiratory syndrome coronavirus.
J.Virol., 87, 2013
5BUQ
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UNLIGANDED FORM OF O-SUCCINYLBENZOATE COENZYME A SYNTHETASE (MENE) FROM BACILLUS SUBTILIS, SOLVED AT 1.98 ANGSTROMS
分子名称:2-succinylbenzoate--CoA ligase, ACETATE ION, CALCIUM ION
著者Chen, Y., Sun, Y., Song, H., Guo, Z.
登録日2015-06-04
公開日2015-08-26
最終更新日2015-10-21
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural Basis for the ATP-dependent Configuration of Adenylation Active Site in Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase
J.Biol.Chem., 290, 2015