Author results

4IQ2
  • Download 4iq2
  • View 4iq2
Molmil generated image of 4iq2
P21 CRYSTAL FORM OF FKBP12.6
分子名称:Peptidyl-prolyl cis-trans isomerase FKBP1B, MALONIC ACID
著者Chen, H., Mustafi, S.M., Li, H.M., LeMaster, D.M., Hernandez, G.
登録日2013-01-10
公開日2014-01-15
最終更新日2015-04-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6.
Acta Crystallogr.,Sect.D, 70, 2014
4IQC
  • Download 4iqc
  • View 4iqc
Molmil generated image of 4iqc
P3121 CRYSTAL FORM OF FKBP12.6
分子名称:Peptidyl-prolyl cis-trans isomerase FKBP1B
著者Chen, H., Mustafi, S.M., Li, H.M., LeMaster, D.M., Hernandez, G.
登録日2013-01-11
公開日2014-01-15
最終更新日2014-09-24
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Crystal structure and conformational flexibility of the unligated FK506-binding protein FKBP12.6.
Acta Crystallogr.,Sect.D, 70, 2014
202D
  • Download 202d
  • View 202d
Molmil generated image of 202d
SOLUTION STRUCTURE OF THE MENOGARIL-DNA COMPLEX
分子名称:DNA (5'-D(*GP*AP*CP*AP*TP*GP*TP*C)-3'), MENOGARIL
著者Chen, H., Patel, D.J.
登録日1995-03-29
公開日1995-06-03
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution Structure of the Menogaril-DNA Complex
J.Am.Chem.Soc., 117, 1995
193D
  • Download 193d
  • View 193d
Molmil generated image of 193d
SOLUTION STRUCTURE OF A QUINOMYCIN BISINTERCALATOR-DNA COMPLEX
分子名称:DNA (5'-D(*AP*CP*AP*CP*GP*TP*GP*T)-3'), QUINOMYCIN, 3-HYDROXYQUINALDIC ACID
著者Chen, H., Patel, D.J.
登録日1994-09-30
公開日1995-02-27
最終更新日2017-11-01
実験手法SOLUTION NMR
主引用文献Solution Structure of a Quinomycin Bisintercalator-DNA Complex.
J.Mol.Biol., 246, 1995
1FJA
  • Download 1fja
  • View 1fja
Molmil generated image of 1fja
NMR STUDY OF DEOXYRIBONUCLEIC ACID COMPLEXED WITH ACTINOMYCIN D
分子名称:DNA (5'-D(*AP*AP*GP*CP*GP*CP*TP*T)-3'), ACTINOMYCIN D
著者Chen, H., Liu, X., Patel, D.J.
登録日1995-12-15
公開日1996-06-10
最終更新日2012-12-12
実験手法SOLUTION NMR
主引用文献DNA Bending and Unwinding Associated with Actinomycin D Antibiotics Bound to Partially Overlapping Sites on DNA.
J.Mol.Biol., 258, 1996
1FJB
  • Download 1fjb
  • View 1fjb
Molmil generated image of 1fjb
NMR STUDY OF AN 11-MER DNA DUPLEX CONTAINING 7,8-DIHYDRO-8-OXOADENINE (AOXO) OPPOSITE THYMINE
分子名称:DNA (5'-D(*GP*CP*AP*TP*GP*TP*GP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*AP*CP*(A38)P*CP*AP*TP*GP*C)-3')
著者Chen, H., Johnson, F., Grollman, A.P., Patel, D.J.
登録日1995-12-15
公開日1996-06-10
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structural Studies of the Ionizing Radiation Adduct 7,8-Dihydro-8-Oxoadenine (A Oxo) Positioned Opposite Thymine and Guanine in DNA Duplexes
MAGN.RESON.CHEM., 34, 1996
2PSQ
  • Download 2psq
  • View 2psq
Molmil generated image of 2psq
CRYSTAL STRUCTURE OF UNPHOSPHORYLATED UNACTIVATED WILD TYPE FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN
分子名称:Fibroblast growth factor receptor 2, SULFATE ION
著者Chen, H., Mohammadi, M.
登録日2007-05-07
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PVF
  • Download 2pvf
  • View 2pvf
Molmil generated image of 2pvf
CRYSTAL STRUCTURE OF TYROSINE PHOSPHORYLATED ACTIVATED FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN IN COMPLEX WITH ATP ANALOG AND SUBSTRATE PEPTIDE
分子名称:Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
著者Chen, H., Mohammadi, M.
登録日2007-05-09
公開日2007-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PVY
  • Download 2pvy
  • View 2pvy
Molmil generated image of 2pvy
CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE PATHOGENIC K659N MUTATION RESPONSIBLE FOR AN UNCLASSIFIED CRANIOSYNOSTOSIS SYNDROME.
分子名称:Fibroblast growth factor receptor 2, SULFATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
著者Chen, H., Mohammadi, M.
登録日2007-05-10
公開日2007-09-25
最終更新日2016-12-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PWL
  • Download 2pwl
  • View 2pwl
Molmil generated image of 2pwl
CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE PATHOGENIC N549H MUTATION RESPONSIBLE FOR CROUZON SYNDROME.
分子名称:Fibroblast growth factor receptor 2, SULFATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
著者Chen, H., Mohammadi, M.
登録日2007-05-11
公開日2007-09-25
最終更新日2016-12-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PY3
  • Download 2py3
  • View 2py3
Molmil generated image of 2py3
CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE PATHOGENIC E565G MUTATION RESPONSIBLE FOR PFEIFFER SYNDROME
分子名称:Fibroblast growth factor receptor 2, SULFATE ION, MAGNESIUM ION, ...
著者Chen, H., Mohammadi, M.
登録日2007-05-15
公開日2007-09-25
最終更新日2016-12-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PZ5
  • Download 2pz5
  • View 2pz5
Molmil generated image of 2pz5
CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE PATHOGENIC N549T MUTATION RESPONSIBLE FOR PFEIFFER SYNDROME
分子名称:Fibroblast growth factor receptor 2, SULFATE ION, MAGNESIUM ION, ...
著者Chen, H., Mohammadi, M.
登録日2007-05-17
公開日2007-09-25
最終更新日2016-12-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PZP
  • Download 2pzp
  • View 2pzp
Molmil generated image of 2pzp
CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE PATHOGENIC K526E MUTATION RESPONSIBLE FOR CROUZON SYNDROME
分子名称:Fibroblast growth factor receptor 2, SULFATE ION, MAGNESIUM ION, ...
著者Chen, H., Mohammadi, M.
登録日2007-05-18
公開日2007-09-25
最終更新日2016-12-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2PZR
  • Download 2pzr
  • View 2pzr
Molmil generated image of 2pzr
CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE PATHOGENIC K641R MUTATION RESPONSIBLE FOR PFEIFFER SYNDROME
分子名称:Fibroblast growth factor receptor 2, SULFATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
著者Chen, H., Mohammadi, M.
登録日2007-05-18
公開日2007-09-25
最終更新日2016-12-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
2Q0B
  • Download 2q0b
  • View 2q0b
Molmil generated image of 2q0b
CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE PATHOGENIC E565A MUTATION RESPONSIBLE FOR PFEIFFER SYNDROME
分子名称:Fibroblast growth factor receptor 2, SULFATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
著者Chen, H., Mohammadi, M.
登録日2007-05-21
公開日2007-09-25
最終更新日2016-12-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
3CLY
  • Download 3cly
  • View 3cly
Molmil generated image of 3cly
CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAINS TRAPPED IN TRANS-PHOSPHORYLATION REACTION
分子名称:Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
著者Chen, H., Mohammadi, M.
登録日2008-03-20
公開日2009-02-03
最終更新日2012-03-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A crystallographic snapshot of tyrosine trans-phosphorylation in action
Proc.Natl.Acad.Sci.USA, 105, 2008
3E17
  • Download 3e17
  • View 3e17
Molmil generated image of 3e17
CRYSTAL STRUCTURE OF THE SECOND PDZ DOMAIN FROM HUMAN ZONA OCCLUDENS-2
分子名称:Tight junction protein ZO-2
著者Chen, H., Tong, S.L., Teng, M.K., Niu, L.W.
登録日2008-08-01
公開日2009-07-21
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of the second PDZ domain from human zonula occludens 2
Acta Crystallogr.,Sect.F, 65, 2009
3MEX
  • Download 3mex
  • View 3mex
Molmil generated image of 3mex
CRYSTAL STRUCTURE OF MEXR IN OXIDIZED STATE
分子名称:Multidrug resistance operon repressor
著者Chen, H., Yi, C., Zhang, J., Zhang, W., Yang, C.-G., He, C.
登録日2010-04-01
公開日2010-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insight into the oxidation-sensing mechanism of the antibiotic resistance of regulator MexR
Embo Rep., 11, 2010
4DM4
  • Download 4dm4
  • View 4dm4
Molmil generated image of 4dm4
THE CONSERVED DOMAIN OF YEAST CDC73
分子名称:Cell division control protein 73
著者Chen, H., Shi, N., Gao, Y., Li, X., Niu, L., Teng, M.
登録日2012-02-06
公開日2012-08-22
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Crystallographic analysis of the conserved C-terminal domain of transcription factor Cdc73 from Saccharomyces cerevisiae reveals a GTPase-like fold.
Acta Crystallogr.,Sect.D, 68, 2012
4J95
  • Download 4j95
  • View 4j95
Molmil generated image of 4j95
CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE PATHOGENIC K659N MUTATION RESPONSIBLE FOR AN UNCLASSIFIED CRANIOSYNOSTOSIS SYNDROME IN SPACE GROUP C2.
分子名称:Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
著者Chen, H., Mohammadi, M.
登録日2013-02-15
公開日2013-08-07
最終更新日2016-12-28
実験手法X-RAY DIFFRACTION (2.3767 Å)
主引用文献Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations.
Cell Rep, 4, 2013
4J96
  • Download 4j96
  • View 4j96
Molmil generated image of 4j96
CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE PATHOGENIC GAIN-OF-FUNCTION K659M MUTATION IDENTIFIED IN CERVICAL CANCER.
分子名称:Fibroblast growth factor receptor 2, SULFATE ION, CITRATE ANION, ...
著者Chen, H., Mohammadi, M.
登録日2013-02-15
公開日2013-08-07
最終更新日2016-12-28
実験手法X-RAY DIFFRACTION (2.2972 Å)
主引用文献Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations.
Cell Rep, 4, 2013
4J97
  • Download 4j97
  • View 4j97
Molmil generated image of 4j97
CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE PATHOGENIC GAIN-OF-FUNCTION K659E MUTATION IDENTIFIED IN ENDOMETRIAL CANCER.
分子名称:Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
著者Chen, H., Mohammadi, M.
登録日2013-02-15
公開日2013-08-07
最終更新日2016-12-28
実験手法X-RAY DIFFRACTION (2.5482 Å)
主引用文献Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations.
Cell Rep, 4, 2013
4J99
  • Download 4j99
  • View 4j99
Molmil generated image of 4j99
CRYSTAL STRUCTURE OF FGF RECEPTOR 2 (FGFR2) KINASE DOMAIN HARBORING THE GAIN-OF-FUNCTION K659T MUTATION.
分子名称:Fibroblast growth factor receptor 2, SULFATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Chen, H., Mohammadi, M.
登録日2013-02-15
公開日2013-08-07
最終更新日2016-12-28
実験手法X-RAY DIFFRACTION (1.8474 Å)
主引用文献Cracking the Molecular Origin of Intrinsic Tyrosine Kinase Activity through Analysis of Pathogenic Gain-of-Function Mutations.
Cell Rep, 4, 2013
5BYY
  • Download 5byy
  • View 5byy
Molmil generated image of 5byy
ERK5 IN COMPLEX WITH SMALL MOLECULE
分子名称:Mitogen-activated protein kinase 7, 2-{[2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
著者Chen, H., Tucker, J., Wang, X., Gavine, P.R., Philips, C., Augustin, M.A., Schreiner, P., Steinbacher, S., Preston, M., Ogg, D.
登録日2015-06-11
公開日2016-05-04
最終更新日2016-05-11
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Discovery of a novel allosteric inhibitor-binding site in ERK5: comparison with the canonical kinase hinge ATP-binding site.
Acta Crystallogr D Struct Biol, 72, 2016
5BYZ
  • Download 5byz
  • View 5byz
Molmil generated image of 5byz
ERK5 IN COMPLEX WITH SMALL MOLECULE
分子名称:Mitogen-activated protein kinase 7, 4-({5-fluoro-4-[2-methyl-1-(propan-2-yl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)-N-[2-(piperidin-1-yl)ethyl]benzamide, GLYCEROL
著者Chen, H., Tucker, J., Wang, X., Gavine, P.R., Philips, C., Augustin, M.A., Schreiner, P., Steinbacher, S., Preston, M., Ogg, D.
登録日2015-06-11
公開日2016-05-04
最終更新日2016-05-11
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Discovery of a novel allosteric inhibitor-binding site in ERK5: comparison with the canonical kinase hinge ATP-binding site.
Acta Crystallogr D Struct Biol, 72, 2016