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3P8C
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STRUCTURE AND CONTROL OF THE ACTIN REGULATORY WAVE COMPLEX
分子名称:Cytoplasmic FMR1-interacting protein 1, Nck-associated protein 1, Wiskott-Aldrich syndrome protein family member 1, ...
著者Chen, Z., Borek, D., Padrick, S.B., Gomez, T.S., Metlagel, Z., Ismail, A.M., Umetani, J., Billadeau, D.D., Otwinowski, Z., Rosen, M.K.
登録日2010-10-13
公開日2010-12-01
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structure and control of the actin regulatory WAVE complex.
Nature, 468, 2010
5H5Z
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CRYSTAL STRUCTURE OF BONY FISH MHC CLASS I, PEPTIDE AND B2M II
分子名称:MHC class I antigen, Beta-2-microglobulin, peptide chain
著者Chen, Z., Zhang, N., Qi, J., Li, X., Chen, R., Wang, Z., Gao, F.G., Xia, C.
登録日2016-11-10
公開日2017-11-22
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural Definition Of Bony Fish MHC Class I Illuminates Several Characteristics Of Peptide-Presentation And Light Chain Binding
To be published
5VF3
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BACTERIOPHAGE T4 ISOMETRIC CAPSID
分子名称:Capsid vertex protein gp24, Major capsid protein, Small outer capsid protein, ...
著者Chen, Z., Sun, L., Zhang, Z., Fokine, A., Padilla-Sanchez, V., Hanein, D., Jiang, W., Rossmann, M.G., Rao, V.B.
登録日2017-04-06
公開日2017-09-13
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of the bacteriophage T4 isometric head at 3.3- angstrom resolution and its relevance to the assembly of icosahedral viruses.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1HSG
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CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES
分子名称:HIV-1 PROTEASE, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE
著者Chen, Z.
登録日1995-03-31
公開日1996-04-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases.
J.Biol.Chem., 269, 1994
1HSH
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CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES
分子名称:HIV-II PROTEASE, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE
著者Chen, Z.
登録日1995-03-31
公開日1996-04-03
最終更新日2014-07-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases.
J.Biol.Chem., 269, 1994
1HSI
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CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES
分子名称:HIV-2 PROTEASE
著者Chen, Z.
登録日1995-03-31
公開日1996-04-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases.
J.Biol.Chem., 269, 1994
3NXP
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CRYSTAL STRUCTURE OF HUMAN PRETHROMBIN-1
分子名称:Prethrombin-1, N-ACETYL-D-GLUCOSAMINE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Chen, Z., Bush-Pelc, L.A., Di Cera, E.
登録日2010-07-14
公開日2010-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of prethrombin-1.
Proc.Natl.Acad.Sci.USA, 107, 2010
2GC4
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STRUCTURAL COMPARISON OF THE OXIDIZED TERNARY ELECTRON TRANSFER COMPLEX OF METHYLAMINE DEHYDROGENASE, AMICYANIN AND CYTOCHROME C551I FROM PARACOCCUS DENITRIFICANS WITH THE SUBSTRATE-REDUCED, COPPER FREE COMPLEX AT 1.9 A RESOLUTION.
分子名称:Methylamine dehydrogenase heavy chain, Methylamine dehydrogenase light chain, Amicyanin, ...
著者Chen, Z., Durley, R., Davidson, V.L., Mathews, F.S.
登録日2006-03-13
公開日2006-11-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural comparison of the oxidized ternary electron transfer complex of methylamine dehydrogenase, amicyanin and cytochrome c551i from Paracoccus denitrificans with the substrate-reduced, copper free complex at 1.9 A resolution.
To be Published
2GC7
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SUBSTRATE REDUCED, COPPER FREE COMPLEX OF METHYLAMINE DEHYDROGENASE, AMICYANIN AND CYTOCHROME C551I FROM PARACOCCUS DENITRIFICANS.
分子名称:Methylamine dehydrogenase heavy chain, Methylamine dehydrogenase light chain, Amicyanin, ...
著者Chen, Z., Durley, R., Davidson, V.L., Mathews, F.S.
登録日2006-03-13
公開日2007-02-06
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structral comparison of the oxidized ternary electron transfer complex of methylamine dehydrogenase, amicyanin and cytochrome c551i from Paracoccus denitrificans with the substrate-reduced, copper free complex at 1.9 A resolution.
To be Published
1AHT
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CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND P-AMIDINOPHENYLPYRUVATE AT 1.6 ANGSTROMS RESOLUTION
分子名称:ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRUGEN, ...
著者Chen, Z.
登録日1995-03-17
公開日1996-03-17
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of human alpha-thrombin complexed with hirugen and p-amidinophenylpyruvate at 1.6 A resolution.
Arch.Biochem.Biophys., 322, 1995
1C6V
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SIV INTEGRASE (CATALYTIC DOMAIN + DNA BIDING DOMAIN COMPRISING RESIDUES 50-293) MUTANT WITH PHE 185 REPLACED BY HIS (F185H)
分子名称:PROTEIN (SIV INTEGRASE), PROTEIN (SIU89134)
著者Chen, Z., Yan, Y., Munshi, S., Li, Y., Zruygay-Murphy, J., Xu, B., Witmer, M., Felock, P., Wolfe, A., Sardana, V., Emini, E.A., Hazuda, D., Kuo, L.C.
登録日1999-12-21
公開日2000-12-27
最終更新日2018-03-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform.
J.Mol.Biol., 296, 2000
1EKM
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CRYSTAL STRUCTURE AT 2.5 A RESOLUTION OF ZINC-SUBSTITUTED COPPER AMINE OXIDASE OF HANSENULA POLYMORPHA EXPRESSED IN ESCHERICHIA COLI
分子名称:COPPER AMINE OXIDASE, ZINC ION
著者Chen, Z., Schwartz, B., Williams, N.K., Li, R., Klinman, J.P., Mathews, F.S.
登録日2000-03-09
公開日2000-08-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure at 2.5 A resolution of zinc-substituted copper amine oxidase of Hansenula polymorpha expressed in Escherichia coli.
Biochemistry, 39, 2000
1FVY
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SOLUTION STRUCTURE OF THE OSTEOGENIC 1-31 FRAGMENT OF THE HUMAN PARATHYROID HORMONE
分子名称:PARATHYROID HORMONE
著者Chen, Z.
登録日2000-09-20
公開日2000-11-22
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Solution structure of the osteogenic 1-31 fragment of the human parathyroid hormone.
Biochemistry, 39, 2000
1SHZ
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CRYSTAL STRUCTURE OF THE P115RHOGEF RGRGS DOMAIN IN A COMPLEX WITH GALPHA(13):GALPHA(I1) CHIMERA
分子名称:Guanine Nucleotide-Binding Protein Galpha(13):Galpha(i1) Chimera, Rho guanine nucleotide exchange factor 1, MAGNESIUM ION, ...
著者Chen, Z., Singer, W.D., Sternweis, P.C., Sprang, S.R.
登録日2004-02-26
公開日2005-01-18
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure of the p115RhoGEF rgRGS domain-Galpha13/i1 chimera complex suggests convergent evolution of a GTPase activator.
Nat.Struct.Mol.Biol., 12, 2005
2GF3
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STRUCTURE OF THE COMPLEX OF MONOMERIC SARCOSINE WITH ITS SUBSTRATE ANALOGUE INHIBITOR 2-FUROIC ACID AT 1.3 A RESOLUTION.
分子名称:Monomeric sarcosine oxidase, CHLORIDE ION, PHOSPHATE ION, ...
著者Chen, Z., Trickey, P., Jorns, M.S., Mathews, F.S.
登録日2006-03-21
公開日2007-02-06
最終更新日2012-03-28
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure of the complex of monomeric sarcosine with its substrate analogue inhibitor 2-furoic acid at 1.3 A resolution.
TO BE PUBLISHED
2GP3
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CRYSTAL STRUCTURE OF THE CATALYTIC CORE DOMAIN OF JMJD2A
分子名称:Jumonji domain-containing protein 2A, ZINC ION, FE (II) ION
著者Chen, Z., Zang, J., Whetstine, J., Hong, X., Davrazou, F., Kutateladze, T.G., Simpson, M., Dai, S., Hagman, J., Shi, Y., Zhang, G.
登録日2006-04-16
公開日2006-05-23
最終更新日2013-11-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural insights into histone demethylation by JMJD2 family members
Cell(Cambridge,Mass.), 125, 2006
2GP5
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CRYSTAL STRUCTURE OF CATALYTIC CORE DOMAIN OF JMJD2A COMPLEXED WITH ALPHA-KETOGLUTARATE
分子名称:Jumonji domain-containing protein 2A, ZINC ION, FE (II) ION, ...
著者Chen, Z., Zang, J., Whetstine, J., Hong, X., Davrazou, F., Kutateladze, T.G., Simpson, M., Dai, S., Hagman, J., Shi, Y., Zhang, G.
登録日2006-04-16
公開日2006-05-23
最終更新日2013-11-27
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural insights into histone demethylation by JMJD2 family members
Cell(Cambridge,Mass.), 125, 2006
2PXJ
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THE COMPLEX STRUCTURE OF JMJD2A AND MONOMETHYLATED H3K36 PEPTIDE
分子名称:JmjC domain-containing histone demethylation protein 3A, monomethylated Histone H3K36 peptide, ZINC ION, ...
著者Chen, Z., Zang, J., Kappler, J., Hong, X., Crawford, F., Zhang, G.
登録日2007-05-14
公開日2007-06-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of the recognition of a methylated histone tail by JMJD2A
Proc.Natl.Acad.Sci.Usa, 104, 2007
3CMT
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MECHANISM OF HOMOLOGOUS RECOMBINATION FROM THE RECA-SSDNA/DSDNA STRUCTURES
分子名称:DNA (5'-D(*DTP*DTP*DTP*DTP*DTP*DCP*DCP*DCP*DAP*DCP*DCP*DTP*DTP*DTP*DT)-3'), DNA (5'-D(P*DGP*DGP*DTP*DGP*DGP*DG)-3'), Protein recA, ...
著者Chen, Z., Yang, H., Pavletich, N.P.
登録日2008-03-24
公開日2008-05-20
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.
Nature, 453, 2008
3DXT
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CRYSTAL STRUCTURE OF THE CATALYTIC CORE DOMAIN OF JMJD2D
分子名称:JmjC domain-containing histone demethylation protein 3D, ZINC ION, SULFATE ION, ...
著者Chen, Z., Zhang, G.
登録日2008-07-25
公開日2009-10-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the catalytic core domain of jmjd2d
To be Published
3DXU
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THE CRYSTAL STRUCTURE OF CORE JMJD2D COMPLEXED WITH FE AND N-OXALYLGLYCINE
分子名称:JmjC domain-containing histone demethylation protein 3D, ZINC ION, FE (II) ION, ...
著者Chen, Z., Zhang, G.
登録日2008-07-25
公開日2009-07-28
最終更新日2018-07-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Crystal Structure of Core Jmjd2D
To be Published
3KZ1
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CRYSTAL STRUCTURE OF THE COMPLEX OF PDZ-RHOGEF DH/PH DOMAINS WITH GTP-GAMMA-S ACTIVATED RHOA
分子名称:Rho guanine nucleotide exchange factor 11, Transforming protein RhoA, MAGNESIUM ION, ...
著者Chen, Z., Sternweis, P.C., Sprang, S.R.
登録日2009-12-07
公開日2010-04-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation.
J.Biol.Chem., 285, 2010
3ODO
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CRYSTAL STRUCTURE OF THE DH/PH DOMAINS OF P115-RHOGEF
分子名称:Rho guanine nucleotide exchange factor 1
著者Chen, Z., Guo, L., Sprang, S.R., Sternweis, P.C.
登録日2010-08-11
公開日2011-01-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3ODW
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CRYSTAL STRUCTURE OF THE LINKER-DH/PH DOMAINS OF P115-RHOGEF
分子名称:Rho guanine nucleotide exchange factor 1
著者Chen, Z., Guo, L., Sprang, S.R., Sternweis, P.C.
登録日2010-08-11
公開日2011-01-05
最終更新日2014-02-19
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3ODX
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CRYSTAL STRUCTURE OF AN N-TERMINALLY TRUNCATED LINKER-DH/PH DOMAINS OF P115-RHOGEF
分子名称:Rho guanine nucleotide exchange factor 1
著者Chen, Z., Guo, L., Sprang, S.R., Sternweis, P.C.
登録日2010-08-12
公開日2011-01-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011