Author results

5CNZ
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CRYSTAL STRUCTURE OF BONY FISH MHC CLASS I, PEPTIDE AND B2M II
Descriptor:MHC class I antigen, Beta-2-microglobulin, PHE-ALA-ASN-PHE-CYS-LEU-MET-MET-ILE
Authors:Chen, Z., Zhang, N., Qi, J., Li, X., Chen, R., Wang, Z., Gao, F.G., Xia, C.
Deposit date:2015-07-18
Release date:2016-10-05
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Crystal structure of bony fish MHC class I, peptide and B2m II
To Be Published
3P8C
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STRUCTURE AND CONTROL OF THE ACTIN REGULATORY WAVE COMPLEX
Descriptor:Cytoplasmic FMR1-interacting protein 1, Nck-associated protein 1, Wiskott-Aldrich syndrome protein family member 1, Probable protein BRICK1, Abl interactor 2
Authors:Chen, Z., Borek, D., Padrick, S.B., Gomez, T.S., Metlagel, Z., Ismail, A.M., Umetani, J., Billadeau, D.D., Otwinowski, Z., Rosen, M.K.
Deposit date:2010-10-13
Release date:2010-12-01
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structure and control of the actin regulatory WAVE complex.
Nature, 468, 2010
1HSG
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CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES
Descriptor:HIV-1 PROTEASE, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE
Authors:Chen, Z.
Deposit date:1995-03-31
Release date:1996-04-03
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases.
J.Biol.Chem., 269, 1994
1HSH
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CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES
Descriptor:HIV-1 PROTEASE, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE
Authors:Chen, Z.
Deposit date:1995-03-31
Release date:1996-04-03
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases.
J.Biol.Chem., 269, 1994
1HSI
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CRYSTAL STRUCTURE AT 1.9 ANGSTROMS RESOLUTION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) II PROTEASE COMPLEXED WITH L-735,524, AN ORALLY BIOAVAILABLE INHIBITOR OF THE HIV PROTEASES
Descriptor:HIV-2 PROTEASE
Authors:Chen, Z.
Deposit date:1995-03-31
Release date:1996-04-03
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure at 1.9-A resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, an orally bioavailable inhibitor of the HIV proteases.
J.Biol.Chem., 269, 1994
3NXP
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CRYSTAL STRUCTURE OF HUMAN PRETHROMBIN-1
Descriptor:Prethrombin-1 (E.C.3.4.21.5)
Authors:Chen, Z., Bush-Pelc, L.A., Di Cera, E.
Deposit date:2010-07-14
Release date:2010-11-10
Last modified:2011-01-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of prethrombin-1.
Proc.Natl.Acad.Sci.USA, 107, 2010
2GC4
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STRUCTURAL COMPARISON OF THE OXIDIZED TERNARY ELECTRON TRANSFER COMPLEX OF METHYLAMINE DEHYDROGENASE, AMICYANIN AND CYTOCHROME C551I FROM PARACOCCUS DENITRIFICANS WITH THE SUBSTRATE-REDUCED, COPPER FREE COMPLEX AT 1.9 A RESOLUTION.
Descriptor:Methylamine dehydrogenase heavy chain (E.C.1.4.99.3), Methylamine dehydrogenase light chain (E.C.1.4.99.3), Amicyanin, Cytochrome c-L
Authors:Chen, Z., Durley, R., Davidson, V.L., Mathews, F.S.
Deposit date:2006-03-13
Release date:2006-11-28
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural comparison of the oxidized ternary electron transfer complex of methylamine dehydrogenase, amicyanin and cytochrome c551i from Paracoccus denitrificans with the substrate-reduced, copper free complex at 1.9 A resolution.
To be Published
2GC7
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SUBSTRATE REDUCED, COPPER FREE COMPLEX OF METHYLAMINE DEHYDROGENASE, AMICYANIN AND CYTOCHROME C551I FROM PARACOCCUS DENITRIFICANS.
Descriptor:Methylamine dehydrogenase heavy chain (E.C.1.4.99.3), Methylamine dehydrogenase light chain (E.C.1.4.99.3), Amicyanin, Cytochrome c-L
Authors:Chen, Z., Durley, R., Davidson, V.L., Mathews, F.S.
Deposit date:2006-03-13
Release date:2007-02-06
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structral comparison of the oxidized ternary electron transfer complex of methylamine dehydrogenase, amicyanin and cytochrome c551i from Paracoccus denitrificans with the substrate-reduced, copper free complex at 1.9 A resolution.
To be Published
1AHT
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CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND P-AMIDINOPHENYLPYRUVATE AT 1.6 ANGSTROMS RESOLUTION
Descriptor:ALPHA-THROMBIN, HIRUGEN, SULFO GROUP, AMIDO PHENYL PYRUVIC ACID
Authors:Chen, Z.
Deposit date:1995-03-17
Release date:1996-03-17
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of human alpha-thrombin complexed with hirugen and p-amidinophenylpyruvate at 1.6 A resolution.
Arch.Biochem.Biophys., 322, 1995
1C6V
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SIV INTEGRASE (CATALYTIC DOMAIN + DNA BIDING DOMAIN COMPRISING RESIDUES 50-293) MUTANT WITH PHE 185 REPLACED BY HIS (F185H)
Descriptor:SIMIAN IMMUNODEFICIENCY VIRUS CONTAINING THE CORE AND C-TERMINAL DOMAIN
Authors:Chen, Z., Yan, Y., Munshi, S., Li, Y., Zruygay-Murphy, J., Xu, B., Witmer, M., Felock, P., Wolfe, A., Sardana, V., Emini, E.A., Hazuda, D., Kuo, L.C.
Deposit date:1999-12-21
Release date:2000-12-27
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform.
J.Mol.Biol., 296, 2000
1EKM
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CRYSTAL STRUCTURE AT 2.5 A RESOLUTION OF ZINC-SUBSTITUTED COPPER AMINE OXIDASE OF HANSENULA POLYMORPHA EXPRESSED IN ESCHERICHIA COLI
Descriptor:COPPER AMINE OXIDASE (E.C.1.4.3.6)
Authors:Chen, Z., Schwartz, B., Williams, N.K., Li, R., Klinman, J.P., Mathews, F.S.
Deposit date:2000-03-09
Release date:2000-08-23
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure at 2.5 A resolution of zinc-substituted copper amine oxidase of Hansenula polymorpha expressed in Escherichia coli.
Biochemistry, 39, 2000
1FVY
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SOLUTION STRUCTURE OF THE OSTEOGENIC 1-31 FRAGMENT OF THE HUMAN PARATHYROID HORMONE
Descriptor:PARATHYROID HORMONE
Authors:Chen, Z.
Deposit date:2000-09-20
Release date:2000-11-22
Last modified:2009-02-24
Method:SOLUTION NMR
Cite:Solution structure of the osteogenic 1-31 fragment of the human parathyroid hormone.
Biochemistry, 39, 2000
1SHZ
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CRYSTAL STRUCTURE OF THE P115RHOGEF RGRGS DOMAIN IN A COMPLEX WITH GALPHA(13):GALPHA(I1) CHIMERA
Descriptor:Guanine Nucleotide-Binding Protein Galpha(13):Galpha(i1) Chimera, Rho guanine nucleotide exchange factor 1
Authors:Chen, Z., Singer, W.D., Sternweis, P.C., Sprang, S.R.
Deposit date:2004-02-26
Release date:2005-01-18
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of the p115RhoGEF rgRGS domain-Galpha13/i1 chimera complex suggests convergent evolution of a GTPase activator.
Nat.Struct.Mol.Biol., 12, 2005
2GF3
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STRUCTURE OF THE COMPLEX OF MONOMERIC SARCOSINE WITH ITS SUBSTRATE ANALOGUE INHIBITOR 2-FUROIC ACID AT 1.3 A RESOLUTION.
Descriptor:Monomeric sarcosine oxidase (E.C.1.5.3.1)
Authors:Chen, Z., Trickey, P., Jorns, M.S., Mathews, F.S.
Deposit date:2006-03-21
Release date:2007-02-06
Last modified:2012-03-28
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of the complex of monomeric sarcosine with its substrate analogue inhibitor 2-furoic acid at 1.3 A resolution.
TO BE PUBLISHED
2GP3
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CRYSTAL STRUCTURE OF THE CATALYTIC CORE DOMAIN OF JMJD2A
Descriptor:Jumonji domain-containing protein 2A
Authors:Chen, Z., Zang, J., Whetstine, J., Hong, X., Davrazou, F., Kutateladze, T.G., Simpson, M., Dai, S., Hagman, J., Shi, Y., Zhang, G.
Deposit date:2006-04-16
Release date:2006-05-23
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural insights into histone demethylation by JMJD2 family members
Cell(Cambridge,Mass.), 125, 2006
2GP5
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CRYSTAL STRUCTURE OF CATALYTIC CORE DOMAIN OF JMJD2A COMPLEXED WITH ALPHA-KETOGLUTARATE
Descriptor:Jumonji domain-containing protein 2A
Authors:Chen, Z., Zang, J., Whetstine, J., Hong, X., Davrazou, F., Kutateladze, T.G., Simpson, M., Dai, S., Hagman, J., Shi, Y., Zhang, G.
Deposit date:2006-04-16
Release date:2006-05-23
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural insights into histone demethylation by JMJD2 family members
Cell(Cambridge,Mass.), 125, 2006
2PXJ
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THE COMPLEX STRUCTURE OF JMJD2A AND MONOMETHYLATED H3K36 PEPTIDE
Descriptor:JmjC domain-containing histone demethylation protein 3A (E.C.1.14.11.-)/monomethylated Histone H3K36 peptide
Authors:Chen, Z., Zang, J., Kappler, J., Hong, X., Crawford, F., Zhang, G.
Deposit date:2007-05-14
Release date:2007-06-12
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of the recognition of a methylated histone tail by JMJD2A
Proc.Natl.Acad.Sci.Usa, 104, 2007
3CMT
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MECHANISM OF HOMOLOGOUS RECOMBINATION FROM THE RECA-SSDNA/DSDNA STRUCTURES
Descriptor:PROTEIN recA/DNA Complex
Authors:Chen, Z., Yang, H., Pavletich, N.P.
Deposit date:2008-03-24
Release date:2008-05-20
Last modified:2009-02-24
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.
Nature, 453, 2008
3DXT
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CRYSTAL STRUCTURE OF THE CATALYTIC CORE DOMAIN OF JMJD2D
Descriptor:JmjC domain-containing histone demethylation protein 3D (E.C.1.14.11.-)
Authors:Chen, Z., Zhang, G.
Deposit date:2008-07-25
Release date:2009-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the catalytic core domain of jmjd2d
To be Published
3DXU
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THE CRYSTAL STRUCTURE OF CORE JMJD2D COMPLEXED WITH FE AND N-OXALYLGLYCINE
Descriptor:JmjC domain-containing histone demethylation protein 3D (E.C.1.14.11.-)
Authors:Chen, Z., Zhang, G.
Deposit date:2008-07-25
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of Core Jmjd2D
To be Published
3KZ1
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CRYSTAL STRUCTURE OF THE COMPLEX OF PDZ-RHOGEF DH/PH DOMAINS WITH GTP-GAMMA-S ACTIVATED RHOA
Descriptor:Rho guanine nucleotide exchange factor 11, Transforming protein RhoA
Authors:Chen, Z., Sternweis, P.C., Sprang, S.R.
Deposit date:2009-12-07
Release date:2010-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation.
J.Biol.Chem., 285, 2010
3ODO
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CRYSTAL STRUCTURE OF THE DH/PH DOMAINS OF P115-RHOGEF
Descriptor:Rho guanine nucleotide exchange factor 1
Authors:Chen, Z., Guo, L., Sprang, S.R., Sternweis, P.C.
Deposit date:2010-08-11
Release date:2011-01-05
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3ODW
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CRYSTAL STRUCTURE OF THE LINKER-DH/PH DOMAINS OF P115-RHOGEF
Descriptor:Rho guanine nucleotide exchange factor 1
Authors:Chen, Z., Guo, L., Sprang, S.R., Sternweis, P.C.
Deposit date:2010-08-11
Release date:2011-01-05
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3ODX
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CRYSTAL STRUCTURE OF AN N-TERMINALLY TRUNCATED LINKER-DH/PH DOMAINS OF P115-RHOGEF
Descriptor:Rho guanine nucleotide exchange factor 1
Authors:Chen, Z., Guo, L., Sprang, S.R., Sternweis, P.C.
Deposit date:2010-08-12
Release date:2011-01-05
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
3P6A
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CRYSTAL STRUCTURE OF THE DH/PH DOMAINS OF P115-RHOGEF (R399E MUTANT)
Descriptor:Rho guanine nucleotide exchange factor 1
Authors:Chen, Z., Guo, L., Sprang, S.R., Sternweis, P.C.
Deposit date:2010-10-11
Release date:2011-01-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoREF
Protein Sci., 20, 2011
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