Author results

4HJE
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CRYSTAL STRUCTURE OF P53 CORE DOMAIN IN COMPLEX WITH DNA
Descriptor:Cellular tumor antigen p53, DNA (5'-D(*TP*CP*AP*CP*AP*AP*GP*TP*TP*AP*GP*AP*GP*AP*CP*AP*AP*GP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*CP*TP*TP*GP*TP*CP*TP*CP*TP*AP*AP*CP*TP*TP*GP*TP*GP*A)-3'), ...
Authors:Chen, Y., Chen, L.
Deposit date:2012-10-12
Release date:2013-07-17
Last modified:2013-10-09
Method:X-RAY DIFFRACTION (1.907 Å)
Cite:Structure of p53 binding to the BAX response element reveals DNA unwinding and compression to accommodate base-pair insertion.
Nucleic Acids Res., 41, 2013
4HC7
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CRYSTAL STRUCTURE OF THE FULL DNA BINDING DOMAIN OF GATA3-COMPLEX 2
Descriptor:Trans-acting T-cell-specific transcription factor GATA-3, DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), ...
Authors:Chen, Y., Bates, D.L., Dey, R., Chen, L.
Deposit date:2012-09-28
Release date:2012-12-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
4HC9
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DNA BINDING BY GATA TRANSCRIPTION FACTOR-COMPLEX 3
Descriptor:Trans-acting T-cell-specific transcription factor GATA-3, DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), ...
Authors:Chen, Y., Bates, D.L., Dey, R., Chen, L.
Deposit date:2012-09-28
Release date:2012-12-05
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
4HCA
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DNA BINDING BY GATA TRANSCRIPTION FACTOR-COMPLEX 1
Descriptor:Trans-acting T-cell-specific transcription factor GATA-3, DNA (5'-D(*AP*AP*TP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*A)-3'), ...
Authors:Chen, Y., Bates, D.L., Dey, R., Chen, L.
Deposit date:2012-09-28
Release date:2012-12-05
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
4WK8
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FOXP3 FORMS A DOMAIN-SWAPPED DIMER TO BRIDGE DNA
Descriptor:DNA (5'-D(*TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*G)-3'), DNA (5'-D(*AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*T)-3'), Forkhead box protein P3
Authors:Chen, Y., Chen, L.
Deposit date:2014-10-01
Release date:2015-01-21
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.4006 Å)
Cite:DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions.
Nucleic Acids Res., 43, 2015
3KMD
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CRYSTAL STRUCTURE OF THE P53 CORE DOMAIN BOUND TO A FULL CONSENSUS SITE AS A SELF-ASSEMBLED TETRAMER
Descriptor:Cellular tumor antigen p53, 5'-D(*GP*GP*GP*CP*AP*TP*GP*CP*CP*TP*AP*GP*GP*CP*AP*TP*GP*CP*C)-3', ZINC ION
Authors:Chen, Y., Dey, R., Chen, L.
Deposit date:2009-11-10
Release date:2010-02-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer.
Structure, 18, 2010
1J48
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CRYSTAL STRUCTURE OF APO-C1027
Descriptor:Apoprotein of C1027
Authors:Chen, Y., Li, J., Liu, Y., Bartlam, M., Gao, Y., Jin, L., Tang, H., Shao, Y., Zhen, Y., Rao, Z.
Deposit date:2001-07-30
Release date:2003-06-03
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Apo-C1027 and Computer Modeling Analysis of C1027 Chromophore- Protein Complex
To be published
5GTD
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O-SUCCINYLBENZOATE COA SYNTHETASE (MENE) FROM BACILLUS SUBTILIS IN COMPLEX WITH THE ACYL-ADENYLATE INTERMEDIATE OSB-AMP
Descriptor:2-succinylbenzoate--CoA ligase, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Chen, Y., Guo, Z.
Deposit date:2016-08-20
Release date:2017-01-04
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Mechanistic Insights from the Crystal Structure of Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase Complexed with the Adenylate Intermediate
Biochemistry, 55, 2016
2HKO
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CRYSTAL STRUCTURE OF LSD1
Descriptor:Lysine-specific histone demethylase 1, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Chen, Y., Yang, Y.T., Wang, F., Yanane, K., Zhang, Y., Lei, M.
Deposit date:2006-07-05
Release date:2006-08-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human histone lysine-specific demethylase 1 (LSD1).
Proc.Natl.Acad.Sci.Usa, 103, 2006
3OWT
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CRYSTAL STRUCTURE OF S. CEREVISIAE RAP1-SIR3 COMPLEX
Descriptor:DNA-binding protein RAP1, Regulatory protein SIR3
Authors:Chen, Y., Yang, Y., Lei, M.
Deposit date:2010-09-20
Release date:2011-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms.
Nat.Struct.Mol.Biol., 18, 2011
3RSN
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CRYSTAL STRUCTURE OF THE N-TERMINAL REGION OF HUMAN ASH2L
Descriptor:Set1/Ash2 histone methyltransferase complex subunit ASH2, ZINC ION
Authors:Chen, Y., Wan, B., Wang, K.C., Cao, F., Yang, Y., Protacio, A., Dou, Y., Chang, H.Y., Lei, M.
Deposit date:2011-05-02
Release date:2011-06-22
Last modified:2011-12-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding.
Embo Rep., 12, 2011
1CZ8
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VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH AN AFFINITY MATURED ANTIBODY
Descriptor:Vascular endothelial growth factor A, LIGHT CHAIN OF NEUTRALIZING ANTIBODY, HEAVY CHAIN OF NEUTRALIZING ANTIBODY, ...
Authors:Chen, Y., Wiesmann, C., Fuh, G., Li, B., Christinger, H.W., McKay, P., de Vos, A.M., Lowman, H.B.
Deposit date:1999-09-01
Release date:2000-03-20
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen.
J.Mol.Biol., 293, 1999
3BQO
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CRYSTAL STRUCTURE OF TRF1 TRFH DOMAIN AND TIN2 PEPTIDE COMPLEX
Descriptor:Telomeric repeat-binding factor 1, TERF1-interacting nuclear factor 2
Authors:Chen, Y., Yang, Y., van Overbeek, M., Donigian, J.R., Baciu, P., de Lange, T., Lei, M.
Deposit date:2007-12-20
Release date:2008-02-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
3BU8
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CRYSTAL STRUCTURE OF TRF2 TRFH DOMAIN AND TIN2 PEPTIDE COMPLEX
Descriptor:Telomeric repeat-binding factor 2, TERF1-interacting nuclear factor 2
Authors:Chen, Y., Yang, Y., van Overbeek, M., Donigian, J.R., Baciu, P., de Lange, T., Lei, M.
Deposit date:2008-01-02
Release date:2008-02-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
3BUA
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CRYSTAL STRUCTURE OF TRF2 TRFH DOMAIN AND APOLLO PEPTIDE COMPLEX
Descriptor:Telomeric repeat-binding factor 2, DNA cross-link repair 1B protein
Authors:Chen, Y., Yang, Y., van Overbeek, M., Donigian, J.R., Baciu, P., de Lange, T., Lei, M.
Deposit date:2008-01-02
Release date:2008-02-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
Science, 319, 2008
3K6G
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CRYSTAL STRUCTURE OF RAP1 AND TRF2 COMPLEX
Descriptor:Telomeric repeat-binding factor 2-interacting protein 1, Telomeric repeat-binding factor 2
Authors:Chen, Y., Rai, R., Yang, Y.T., Zheng, H., Chang, S., Lei, M.
Deposit date:2009-10-08
Release date:2010-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms.
Nat.Struct.Mol.Biol., 18, 2011
3TOJ
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STRUCTURE OF THE SPRY DOMAIN OF HUMAN ASH2L
Descriptor:Set1/Ash2 histone methyltransferase complex subunit ASH2
Authors:Chen, Y., Cao, F., Wan, B., Dou, Y., Lei, M.
Deposit date:2011-09-05
Release date:2012-01-25
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30.
Cell Res., 22, 2012
4IK1
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HIGH RESOLUTION STRUCTURE OF GCAMPJ AT PH 8.5
Descriptor:RCaMP, Green fluorescent protein, CALCIUM ION
Authors:Chen, Y., Song, X., Miao, L., Zhu, Y., Ji, G.
Deposit date:2012-12-25
Release date:2014-02-05
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
4IK3
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HIGH RESOLUTION STRUCTURE OF GCAMP3 AT PH 8.5
Descriptor:RCaMP, Green fluorescent protein, CALCIUM ION
Authors:Chen, Y., Song, X., Miao, L., Zhu, Y., Ji, G.
Deposit date:2012-12-25
Release date:2014-01-29
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.007 Å)
Cite:Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
4IK4
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HIGH RESOLUTION STRUCTURE OF GCAMP3 AT PH 5.0
Descriptor:RCaMP, Green fluorescent protein, CALCIUM ION
Authors:Chen, Y., Song, X., Miao, L., Zhu, Y., Ji, G.
Deposit date:2012-12-25
Release date:2014-02-05
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
4IK5
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HIGH RESOLUTION STRUCTURE OF DELTA-REST-GCAMP3
Descriptor:RCaMP, Green fluorescent protein, CALCIUM ION
Authors:Chen, Y., Song, X., Miao, L., Zhu, Y., Ji, G.
Deposit date:2012-12-25
Release date:2014-01-29
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
4IK8
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HIGH RESOLUTION STRUCTURE OF GCAMP3 DIMER FORM 1 AT PH 7.5
Descriptor:RCaMP, Green fluorescent protein, CALCIUM ION
Authors:Chen, Y., Song, X., Miao, L., Zhu, Y., Ji, G.
Deposit date:2012-12-25
Release date:2014-02-05
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
4IK9
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HIGH RESOLUTION STRUCTURE OF GCAMP3 DIMER FORM 2 AT PH 7.5
Descriptor:RCaMP, Green fluorescent protein, CALCIUM ION, ...
Authors:Chen, Y., Song, X., Miao, L., Zhu, Y., Ji, G.
Deposit date:2012-12-25
Release date:2014-01-29
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insight into enhanced calcium indicator GCaMP3 and GCaMPJ to promote further improvement.
Protein Cell, 4, 2013
4L3N
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CRYSTAL STRUCTURE OF THE RECEPTOR-BINDING DOMAIN FROM NEWLY EMERGED MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS
Descriptor:S protein, 1,2-ETHANEDIOL, N-ACETYL-D-GLUCOSAMINE
Authors:Chen, Y., Rajashankar, K.R., Yang, Y., Agnihothram, S.S., Liu, C., Lin, Y.-L., Baric, R.S., Li, F.
Deposit date:2013-06-06
Release date:2013-07-31
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Crystal structure of the receptor-binding domain from newly emerged middle East respiratory syndrome coronavirus.
J.Virol., 87, 2013
5BUQ
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UNLIGANDED FORM OF O-SUCCINYLBENZOATE COENZYME A SYNTHETASE (MENE) FROM BACILLUS SUBTILIS, SOLVED AT 1.98 ANGSTROMS
Descriptor:2-succinylbenzoate--CoA ligase, ACETATE ION, CALCIUM ION
Authors:Chen, Y., Sun, Y., Song, H., Guo, Z.
Deposit date:2015-06-04
Release date:2015-08-26
Last modified:2015-10-21
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural Basis for the ATP-dependent Configuration of Adenylation Active Site in Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase
J.Biol.Chem., 290, 2015
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