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5ZEN
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BU of 5zen by Molmil
Crystal structure of human topoisomerase II beta in complex with DNA: a new quaternary conformation showing opening of the protein-linked DNA-gate
Descriptor: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ...
Authors:Chen, S.F, Wang, Y.R, Chan, N.L.
Deposit date:2018-02-27
Release date:2018-08-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural insights into the gating of DNA passage by the topoisomerase II DNA-gate.
Nat Commun, 9, 2018
5ZQF
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BU of 5zqf by Molmil
Crystal structure of human topoisomerase II beta in complex with 5-iodouridine-containing-DNA in space group P3221
Descriptor: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA topoisomerase 2-beta, DNA/RNA (5'-D(P*AP*GP*C)-R(P*(IU))-D(P*CP*GP*GP*C)-R(P*(IU))-3'), ...
Authors:Chen, S.F, Wang, Y.R, Chan, N.L.
Deposit date:2018-04-18
Release date:2018-08-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.873 Å)
Cite:Structural insights into the gating of DNA passage by the topoisomerase II DNA-gate.
Nat Commun, 9, 2018
5ZRF
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BU of 5zrf by Molmil
Crystal structure of human topoisomerase II beta in complex with 5-iodouridine-containing-DNA and etoposide in space group p21
Descriptor: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA topoisomerase 2-beta, ...
Authors:Chen, S.F, Wang, Y.R, Wu, C.C, Chan, N.L.
Deposit date:2018-04-24
Release date:2018-08-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the gating of DNA passage by the topoisomerase II DNA-gate.
Nat Commun, 9, 2018
4ZGZ
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BU of 4zgz by Molmil
STRUCTURE OF HUMAN ANTIZYME INHIBITOR IN COMPLEX WITH A C-TERMINAL FRAGMENT OF ANTIZYME
Descriptor: Antizyme inhibitor 1, Ornithine decarboxylase antizyme 1
Authors:Chen, S.F, Wu, H.Y, Chan, N.L.
Deposit date:2015-04-24
Release date:2015-09-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (5.81 Å)
Cite:Structural basis of antizyme-mediated regulation of polyamine homeostasis
Proc.Natl.Acad.Sci.USA, 112, 2015
5GWI
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BU of 5gwi by Molmil
Structure of a Human topoisomerase IIbeta fragment in complex with DNA and E7873R
Descriptor: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ...
Authors:Wang, Y.R, Chen, S.F, Wu, C.C, Chan, N.L.
Deposit date:2016-09-12
Release date:2017-08-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.737 Å)
Cite:Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Nucleic Acids Res., 45, 2017
5GWJ
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BU of 5gwj by Molmil
Structure of a Human topoisomerase IIbeta fragment in complex with DNA and E7873S
Descriptor: DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), DNA topoisomerase 2-beta, ...
Authors:Wang, Y.R, Chen, S.F, Wu, C.C, Chan, N.L.
Deposit date:2016-09-12
Release date:2017-08-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.566 Å)
Cite:Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Nucleic Acids Res., 45, 2017
7KPW
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BU of 7kpw by Molmil
Structure of the H-lobe of yeast CKM
Descriptor: Mediator of RNA polymerase II transcription subunit 12
Authors:Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L.
Deposit date:2020-11-12
Release date:2021-01-27
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module.
Sci Adv, 7, 2021
7KPV
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BU of 7kpv by Molmil
Structure of kinase and Central lobes of yeast CKM
Descriptor: Mediator of RNA polymerase II transcription subunit 12, Mediator of RNA polymerase II transcription subunit 13, Meiotic mRNA stability protein kinase SSN3, ...
Authors:Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L.
Deposit date:2020-11-12
Release date:2021-01-27
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module.
Sci Adv, 7, 2021
7KPX
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BU of 7kpx by Molmil
Structure of the yeast CKM
Descriptor: Mediator of RNA polymerase II transcription subunit 12, Mediator of RNA polymerase II transcription subunit 13, Meiotic mRNA stability protein kinase SSN3, ...
Authors:Li, Y.C, Chao, T.C, Kim, H.J, Cholko, T, Chen, S.F, Nakanishi, K, Chang, C.E, Murakami, K, Garcia, B.A, Boyer, T.G, Tsai, K.L.
Deposit date:2020-11-12
Release date:2021-01-27
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure and noncanonical Cdk8 activation mechanism within an Argonaute-containing Mediator kinase module.
Sci Adv, 7, 2021
5GWK
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BU of 5gwk by Molmil
Human topoisomerase IIalpha in complex with DNA and etoposide
Descriptor: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ...
Authors:Wang, Y.R, Wu, C.C, Chan, N.L.
Deposit date:2016-09-12
Release date:2017-08-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.152 Å)
Cite:Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Nucleic Acids Res., 45, 2017
4ZGY
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BU of 4zgy by Molmil
STRUCTURE of HUMAN ORNITHINE DECARBOXYLASE IN COMPLEX WITH A C-TERMINAL FRAGMENT OF ANTIZYME
Descriptor: MAGNESIUM ION, Ornithine decarboxylase, Ornithine decarboxylase antizyme 1, ...
Authors:Wu, H.Y, Chan, N.L.
Deposit date:2015-04-24
Release date:2015-09-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Structural basis of antizyme-mediated regulation of polyamine homeostasis
Proc.Natl.Acad.Sci.USA, 112, 2015
7UIG
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BU of 7uig by Molmil
Mediator-PIC Early (Mediator A)
Descriptor: DNA-directed RNA polymerase II subunit RPB1, Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, ...
Authors:Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
Deposit date:2022-03-29
Release date:2023-02-15
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIL
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BU of 7uil by Molmil
Mediator-PIC Early (Tail A/B Dimer)
Descriptor: Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 14, Mediator of RNA polymerase II transcription subunit 15, ...
Authors:Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
Deposit date:2022-03-29
Release date:2023-02-15
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIC
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BU of 7uic by Molmil
Mediator-PIC Early (Tail A)
Descriptor: Mediator of RNA polymerase II transcription subunit 14, Mediator of RNA polymerase II transcription subunit 15, Mediator of RNA polymerase II transcription subunit 16, ...
Authors:Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
Deposit date:2022-03-29
Release date:2023-02-15
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UI9
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BU of 7ui9 by Molmil
Core Mediator-PICearly (Copy A)
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
Deposit date:2022-03-28
Release date:2023-02-15
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIF
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BU of 7uif by Molmil
Mediator-PIC Early (Core B)
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
Deposit date:2022-03-29
Release date:2023-02-15
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIK
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BU of 7uik by Molmil
Mediator-PIC Early (Tail A + Upstream DNA & Activator)
Descriptor: DNA (37-MER), DNA (38-MER), Mediator of RNA polymerase II transcription subunit 14, ...
Authors:Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
Deposit date:2022-03-29
Release date:2023-03-01
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
7UIO
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BU of 7uio by Molmil
Mediator-PIC Early (Composite Model)
Descriptor: ALANINE, ASPARTIC ACID, DNA (37-MER), ...
Authors:Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
Deposit date:2022-03-29
Release date:2023-03-01
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023

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PDB entries from 2024-03-27

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