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Structure of a stapled peptide antagonist bound to Nutlin-resistant Mdm2.
Descriptor:	E3 ubiquitin-protein ligase Mdm2, M06
Authors:	Chee, S, Wongsantichon, J, Quah, S, Robinson, R.C, Verma, C, Lane, D.P, Brown, C.J, Ghadessy, F.J.
Deposit date:	2014-05-20
Release date:	2014-05-28
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (1.99 Å)
Cite:	Structure of a stapled peptide antagonist bound to nutlin-resistant Mdm2. PLoS ONE, 9, 2014

Macrocyclization of an all-D linear peptide improves target affinity and imparts cellular activity: A novel stapled alpha-helical peptide modality
Descriptor:	2JN-DAL-E03-DTY-2JN-DSG-TDF-DGL-MK8-DLE-DLE-2JN, E3 ubiquitin-protein ligase Mdm2
Authors:	Jiang, S, Brown, C.J.
Deposit date:	2019-09-25
Release date:	2019-10-16
Last modified:	2023-11-22
Method:	X-RAY DIFFRACTION (1.79 Å)
Cite:	Macrocyclization of an all-d linear alpha-helical peptide imparts cellular permeability. Chem Sci, 11, 2020