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1SNT
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STRUCTURE OF THE HUMAN CYTOSOLIC SIALIDASE NEU2
Descriptor:Sialidase 2
Authors:Chavas, L.M.G., Fusi, P., Tringali, C., Venerando, B., Tettamanti, G., Kato, R., Monti, E., Wakatsuki, S.
Deposit date:2004-03-12
Release date:2004-11-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal Structure of the Human Cytosolic Sialidase Neu2: EVIDENCE FOR THE DYNAMIC NATURE OF SUBSTRATE RECOGNITION
J.Biol.Chem., 280, 2005
1SO7
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MALTOSE-INDUCED STRUCTURE OF THE HUMAN CYTOLSOLIC SIALIDASE NEU2
Descriptor:Sialidase 2, CHLORIDE ION
Authors:Chavas, L.M.G., Fusi, P., Tringali, C., Venerando, B., Tettamanti, G., Kato, R., Monti, E., Wakatsuki, S.
Deposit date:2004-03-12
Release date:2004-11-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Crystal Structure of the Human Cytosolic Sialidase Neu2: EVIDENCE FOR THE DYNAMIC NATURE OF SUBSTRATE RECOGNITION
J.Biol.Chem., 280, 2005
1VCU
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STRUCTURE OF THE HUMAN CYTOSOLIC SIALIDASE NEU2 IN COMPLEX WITH THE INHIBITOR DANA
Descriptor:Sialidase 2, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Chavas, L.M.G., Fusi, P., Tringali, C., Venerando, B., Tettamanti, G., Kato, R., Monti, E., Wakatsuki, S.
Deposit date:2004-03-12
Release date:2004-11-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal Structure of the Human Cytosolic Sialidase Neu2: EVIDENCE FOR THE DYNAMIC NATURE OF SUBSTRATE RECOGNITION
J.Biol.Chem., 280, 2005
2F0Z
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CRYSTAL STRUCTURE OF THE HUMAN SIALIDASE NEU2 IN COMPLEX WITH ZANAMIVIR INHIBITOR
Descriptor:Sialidase 2, ZANAMIVIR
Authors:Chavas, L.M.G., Kato, R., McKimm-Breschkin, J., Colman, P.M., Fusi, P., Tringali, C., Venerando, B., Tettamanti, G., Monti, E., Wakatsuki, S.
Deposit date:2005-11-14
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of the Human Sialidase Neu2 in Complex with Zanamivir inhibitor
To be Published
2F10
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CRYSTAL STRUCTURE OF THE HUMAN SIALIDASE NEU2 IN COMPLEX WITH PERAMIVIR INHIBITOR
Descriptor:Sialidase 2, PHOSPHATE ION, 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID
Authors:Chavas, L.M.G., Kato, R., McKimm-Breschkin, J., Colman, P.M., Fusi, P., Tringali, C., Venerando, B., Tettamanti, G., Monti, E., Wakatsuki, S.
Deposit date:2005-11-14
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of the Human Sialidase Neu2 in Complex with Peramivir inhibitor
To be Published
2F11
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CRYSTAL STRUCTURE OF THE HUMAN SIALIDASE NEU2 IN COMPLEX WITH ISOBUTYL ETHER MIMETIC INHIBITOR
Descriptor:Sialidase 2, PHOSPHATE ION, 5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID
Authors:Chavas, L.M.G., Kato, R., Mann, M.C., Thomson, R.J., Dyason, J.C., von Itzstein, M., Fusi, P., Tringali, C., Venerando, B., Tettamanti, G., Monti, E., Wakatsuki, S.
Deposit date:2005-11-14
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Crystal Structure of the Human Sialidase Neu2 in Complex with isobutyl ether mimetic Inhibitor
To be Published
2F12
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CRYSTAL STRUCTURE OF THE HUMAN SIALIDASE NEU2 IN COMPLEX WITH 3- HYDROXYPROPYL ETHER MIMETIC INHIBITOR
Descriptor:Sialidase 2, PHOSPHATE ION, 6-(3-HYDROXYPROPOXY)-5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-4H-PYRAN-2-CARBOXYLIC ACID
Authors:Chavas, L.M.G., Kato, R., Mann, M.C., Thomson, R.J., Dyason, J.C., von Itzstein, M., Fusi, P., Tringali, C., Venerando, B., Tettamanti, G., Monti, E., Wakatsuki, S.
Deposit date:2005-11-14
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal Structure of the Human Sialidase Neu2 in Complex with 3- hydroxypropyl ether mimetic Inhibitor
To be Published
2F13
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CRYSTAL STRUCTURE OF THE HUMAN SIALIDASE NEU2 IN COMPLEX WITH 2',3'- DIHYDROXYPROPYL ETHER MIMETIC INHIBITOR
Descriptor:Sialidase 2, PHOSPHATE ION, 6-(2,3-DIHYDROXYPROPOXY)-5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-4H-PYRAN-2-CARBOXYLIC ACID
Authors:Chavas, L.M.G., Kato, R., Mann, M.C., Thomson, R.J., Dyason, J.C., von Itzstein, M., Fusi, P., Tringali, C., Venerando, B., Tettamanti, G., Monti, E., Wakatsuki, S.
Deposit date:2005-11-14
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Crystal Structure of the Human Sialidase Neu2 in Complex with 2',3'- dihydroxypropyl ether mimetic Inhibitor
To be Published
2F24
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CRYSTAL STRUCTURE OF THE HUMAN SIALIDASE NEU2 E111Q MUTANT
Descriptor:Sialidase 2, CHLORIDE ION
Authors:Chavas, L.M.G., Kato, R., Fusi, P., Tringali, C., Venerando, B., Tettamanti, G., Monti, E., Wakatsuki, S.
Deposit date:2005-11-15
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Crystal Structure of the Human Sialidase Neu2 E111Q Mutant
To be Published
2F25
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CRYSTAL STRUCTURE OF THE HUMAN SIALIDASE NEU2 E111Q MUTANT IN COMPLEX WITH DANA INHIBITOR
Descriptor:Sialidase 2, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Chavas, L.M.G., Kato, R., Fusi, P., Tringali, C., Venerando, B., Tettamanti, G., Monti, E., Wakatsuki, S.
Deposit date:2005-11-15
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of the Human Sialidase Neu2 E111Q Mutant in Complex with DANA Inhibitor
To be Published
2F26
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CRYSTAL STRUCTURE OF THE HUMAN SIALIDASE NEU2 E111Q-Q112E DOUBLE MUTANT
Descriptor:Sialidase 2, CHLORIDE ION
Authors:Chavas, L.M.G., Kato, R., Fusi, P., Tringali, C., Venerando, B., Tettamanti, G., Monti, E., Wakatsuki, S.
Deposit date:2005-11-15
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant
To be Published
2F27
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CRYSTAL STRUCTURE OF THE HUMAN SIALIDASE NEU2 E111Q-Q112E DOUBLE MUTANT IN COMPLEX WITH DANA INHIBITOR
Descriptor:Sialidase 2, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Chavas, L.M.G., Kato, R., Fusi, P., Tringali, C., Venerando, B., Tettamanti, G., Monti, E., Wakatsuki, S.
Deposit date:2005-11-15
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant in Complex with DANA Inhibitor
To be Published
2F28
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CRYSTAL STRUCTURE OF THE HUMAN SIALIDASE NEU2 Q116E MUTANT
Descriptor:Sialidase 2, CHLORIDE ION
Authors:Chavas, L.M.G., Kato, R., Fusi, P., Tringali, C., Venerando, B., Tettamanti, G., Monti, E., Wakatsuki, S.
Deposit date:2005-11-15
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Crystal Structure of the Human Sialidase Neu2 Q116E Mutant
To be Published
2F29
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CRYSTAL STRUCTURE OF THE HUMAN SIALIDASE NEU2 Q116E MUTANT IN COMPLEX WITH DANA INHIBITOR
Descriptor:Sialidase 2, 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
Authors:Chavas, L.M.G., Kato, R., Fusi, P., Tringali, C., Venerando, B., Tettamanti, G., Monti, E., Wakatsuki, S.
Deposit date:2005-11-15
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.921 Å)
Cite:Crystal Structure of the Human Sialidase Neu2 Q116E Mutant in Complex with DANA Inhibitor
To be Published
2IEY
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CRYSTAL STRUCTURE OF MOUSE RAB27B BOUND TO GDP IN HEXAGONAL SPACE GROUP
Descriptor:Ras-related protein Rab-27B, GUANOSINE-5'-DIPHOSPHATE
Authors:Chavas, L.M.G., Torii, S., Kamikubo, H., Kawasaki, M., Ihara, K., Kato, R., Kataoka, M., Izumi, T., Wakatsuki, S.
Deposit date:2006-09-19
Release date:2007-05-01
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Structure of the small GTPase Rab27b shows an unexpected swapped dimer
Acta Crystallogr.,Sect.D, 63, 2007
2IEZ
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CRYSTAL STRUCTURE OF MOUSE RAB27B BOUND TO GDP IN MONOCLINIC SPACE GROUP
Descriptor:Ras-related protein Rab-27B, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Chavas, L.M.G., Torii, S., Kamikubo, H., Kawasaki, M., Ihara, K., Kato, R., Kataoka, M., Izumi, T., Wakatsuki, S.
Deposit date:2006-09-19
Release date:2007-05-01
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the small GTPase Rab27b shows an unexpected swapped dimer
Acta Crystallogr.,Sect.D, 63, 2007
2IF0
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CRYSTAL STRUCTURE OF MOUSE RAB27B BOUND TO GDP IN MONOCLINIC SPACE GROUP
Descriptor:Ras-related protein Rab-27B, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Chavas, L.M.G., Torii, S., Kamikubo, H., Kawasaki, M., Ihara, K., Kato, R., Kataoka, M., Izumi, T., Wakatsuki, S.
Deposit date:2006-09-19
Release date:2007-05-01
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the small GTPase Rab27b shows an unexpected swapped dimer
Acta Crystallogr.,Sect.D, 63, 2007
3BC1
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CRYSTAL STRUCTURE OF THE COMPLEX RAB27A-SLP2A
Descriptor:Ras-related protein Rab-27A, Synaptotagmin-like protein 2, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Chavas, L.M.G., Ihara, K., Kawasaki, M., Wakatsuki, S.
Deposit date:2007-11-12
Release date:2008-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/Slp2-a
Structure, 16, 2008
4NYQ
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IN-VIVO CRYSTALLISATION (MIDGUTS OF A VIVIPAROUS COCKROACH) AND STRUCTURE AT 1.2 A RESOLUTION OF A GLYCOSYLATED, LIPID-BINDING, LIPOCALIN-LIKE PROTEIN
Descriptor:Milk protein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Coussens, N.P., Gallat, F.-X., Ramaswamy, S., Yagi, K., Tobe, S.S., Stay, B., Chavas, L.M.G.
Deposit date:2013-12-11
Release date:2014-01-01
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure of a heterogeneous, glycosylated, lipid-bound, in vivo-grown protein crystal at atomic resolution from the viviparous cockroach Diploptera punctata
IUCRJ, 3, 2016
4NYR
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IN-VIVO CRYSTALLISATION (MIDGUTS OF A VIVIPAROUS COCKROACH) AND STRUCTURE AT 2.5 A RESOLUTION OF A GLYCOSYLATED, LIPID-BINDING, LIPOCALIN-LIKE PROTEIN
Descriptor:Milk protein, N-ACETYL-D-GLUCOSAMINE, GLYCEROL
Authors:Coussens, N.P., Gallat, F.-X., Ramaswamy, S., Yagi, K., Tobe, S.S., Stay, B., Chavas, L.M.G.
Deposit date:2013-12-11
Release date:2014-01-01
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structure of a heterogeneous, glycosylated, lipid-bound, in vivo-grown protein crystal at atomic resolution from the viviparous cockroach Diploptera punctata
IUCRJ, 3, 2016
5EPQ
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STRUCTURE AT 1.75 A RESOLUTION OF A GLYCOSYLATED, LIPID-BINDING, LIPOCALIN-LIKE PROTEIN
Descriptor:Milk protein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Banerjee, S., Chavas, L.M.G., Ramaswamy, S.
Deposit date:2015-11-12
Release date:2015-12-02
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Structure of a heterogeneous, glycosylated, lipid-bound, in vivo-grown protein crystal at atomic resolution from the viviparous cockroach Diploptera punctata
Iucrj, 3, 2016
5KV8
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CRYSTAL STRUCTURE OF A HPIV HAEMAGGLUTININ-NEURAMINIDASE-INHIBITOR COMPLEX
Descriptor:Hemagglutinin-neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Dirr, L., El-Deeb, I.M., Chavas, L.M.G., Guillon, P., von Itzstein, M.
Deposit date:2016-07-13
Release date:2017-07-12
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design.
Sci Rep, 7, 2017
5KV9
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CRYSTAL STRUCTURE OF A HPIV HAEMAGGLUTININ-NEURAMINIDASE-INHIBITOR COMPLEX
Descriptor:Hemagglutinin-neuraminidase, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Dirr, L., El-Deeb, I.M., Chavas, L.M.G., Guillon, P., von Itzstein, M.
Deposit date:2016-07-13
Release date:2017-07-12
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design.
Sci Rep, 7, 2017
2ZMC
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CRYSTAL STRUCTURE OF HUMAN MITOTIC CHECKPOINT KINASE MPS1 CATALYTIC DOMAIN APO FORM
Descriptor:Dual specificity protein kinase TTK, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL
Authors:Chu, M.L.H., Chavas, L.M.G., Douglas, K.T., Eyers, P.A., Tabernero, L.
Deposit date:2008-04-16
Release date:2008-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.14 Å)
Cite:Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125.
J.Biol.Chem., 283, 2008
2ZMD
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CRYSTAL STRUCTURE OF HUMAN MPS1 CATALYTIC DOMAIN T686A MUTANT IN COMPLEX WITH SP600125 INHIBITOR
Descriptor:Dual specificity protein kinase TTK, 2,6-DIHYDROANTHRA/1,9-CD/PYRAZOL-6-ONE, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL
Authors:Chu, M.L.H., Chavas, L.M.G., Douglas, K.T., Eyers, P.A., Tabernero, L.
Deposit date:2008-04-16
Release date:2008-05-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125.
J.Biol.Chem., 283, 2008
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