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3S8S
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BU of 3s8s by Molmil
Crystal structure of the RRM domain of human SETD1A
Descriptor: Histone-lysine N-methyltransferase SETD1A, UNKNOWN ATOM OR ION
Authors:Chao, X, Tempel, W, Bian, C, Cerovina, T, Walker, J.R, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-05-30
Release date:2011-06-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of the RRM domain of human SETD1A
to be published
3S93
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BU of 3s93 by Molmil
Crystal structure of conserved motif in TDRD5
Descriptor: Tudor domain-containing protein 5, UNKNOWN ATOM OR ION
Authors:Chao, X, Tempel, W, Bian, C, Kania, J, Wernimont, A.K, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-05-31
Release date:2011-08-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of conserved motif in TDRD5
to be published
2F9Z
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BU of 2f9z by Molmil
Complex between the chemotaxis deamidase CheD and the chemotaxis phosphatase CheC from Thermotoga maritima
Descriptor: PROTEIN (chemotaxis methylation protein), chemotaxis protein CheC
Authors:Chao, X, Park, S.Y, Bilwes, A.M, Crane, B.R.
Deposit date:2005-12-06
Release date:2006-06-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A receptor-modifying deamidase in complex with a signaling phosphatase reveals reciprocal regulation.
Cell(Cambridge,Mass.), 124, 2006
1XKR
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BU of 1xkr by Molmil
X-ray Structure of Thermotoga maritima CheC
Descriptor: chemotaxis protein CheC
Authors:Park, S.Y, Chao, X, Gonzalez-Bonet, G, Beel, B.D, Bilwes, A.M, Crane, B.R.
Deposit date:2004-09-29
Release date:2004-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure and Function of an Unusual Family of Protein Phosphatases; The Bacterial Chemotaxis Proteins CheC and CheX
Mol.Cell, 16, 2004
1XKO
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BU of 1xko by Molmil
Structure of Thermotoga maritima CheX
Descriptor: CHEMOTAXIS protein cheX
Authors:Park, S.Y, Chao, X, Gonzalez-Bonet, G, Beel, B.D, Bilwes, A.M, Crane, B.R.
Deposit date:2004-09-29
Release date:2004-12-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structure and Function of an Unusual Family of Protein Phosphatases; The Bacterial Chemotaxis Proteins CheC and CheX.
Mol.Cell, 16, 2004
4II1
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BU of 4ii1 by Molmil
Crystal structure of the zinc finger of ZGPAT
Descriptor: UNKNOWN ATOM OR ION, ZINC ION, Zinc finger CCCH-type with G patch domain-containing protein
Authors:Bian, C, Tempel, W, Dong, A, Chao, X, Fu, M, Wernimont, A.K, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2012-12-19
Release date:2013-02-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of the zinc finger of ZGPAT
to be published
4PZI
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BU of 4pzi by Molmil
Zinc finger region of MLL2 in complex with CpG DNA
Descriptor: DNA (5'-D(*GP*CP*CP*AP*CP*CP*GP*GP*TP*GP*GP*C)-3'), Histone-lysine N-methyltransferase 2B, UNKNOWN ATOM OR ION, ...
Authors:Chao, X, Tempel, W, Liu, K, Dong, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2014-03-31
Release date:2014-06-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 26, 2018
4HP3
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BU of 4hp3 by Molmil
Crystal structure of Tet3 in complex with a CpG dsDNA
Descriptor: DNA (5'-D(*GP*CP*CP*AP*AP*CP*GP*TP*TP*GP*GP*C)-3'), LOC100036628 protein, UNKNOWN ATOM OR ION, ...
Authors:Chao, X, Tempel, W, Bian, C, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2012-10-23
Release date:2012-12-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development.
Cell(Cambridge,Mass.), 151, 2012
4HP1
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BU of 4hp1 by Molmil
Crystal structure of Tet3 in complex with a non-CpG dsDNA
Descriptor: DNA (5'-D(*GP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*C)-3'), LOC100036628 protein, ZINC ION
Authors:Chao, X, Tempel, W, Bian, C, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2012-10-23
Release date:2012-12-05
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development.
Cell(Cambridge,Mass.), 151, 2012
5TEF
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BU of 5tef by Molmil
Crystal structure of Gemin5 WD40 repeats in complex with m7GpppG
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, GLYCEROL, Gem-associated protein 5, ...
Authors:Chao, X, Tempel, W, Bian, C, He, H, Cerovina, T, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2016-09-21
Release date:2016-10-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly.
Genes Dev., 30, 2016
5TEE
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BU of 5tee by Molmil
Crystal structure of Gemin5 WD40 repeats in apo form
Descriptor: GLYCEROL, Gem-associated protein 5, SODIUM ION, ...
Authors:Chao, X, Tempel, W, Bian, C, Cerovina, T, He, H, Walker, J.R, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2016-09-21
Release date:2016-10-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly.
Genes Dev., 30, 2016
5THA
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BU of 5tha by Molmil
Gemin5 WD40 repeats in complex with a guanosyl moiety
Descriptor: DIGUANOSINE-5'-TRIPHOSPHATE, Gem-associated protein 5, UNKNOWN ATOM OR ION
Authors:Chao, X, Tempel, W, Bian, C, Cerovina, T, He, H, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2016-09-29
Release date:2016-10-19
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly.
Genes Dev., 30, 2016
7X1W
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BU of 7x1w by Molmil
Cryo-EM structure of human ABCD1 E630Q in the presence of ATP in inward-facing state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 1
Authors:Chao, X, Li-Na, J, Lin, T.
Deposit date:2022-02-24
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP.
Signal Transduct Target Ther, 8, 2023
7X07
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BU of 7x07 by Molmil
Cryo-EM structure of human ABCD1 in the presence of C26:0
Descriptor: ATP-binding cassette sub-family D member 1, hexacosanoic acid
Authors:Chao, X, Li-Na, J, Lin, T.
Deposit date:2022-02-21
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP.
Signal Transduct Target Ther, 8, 2023
7X0T
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BU of 7x0t by Molmil
Cryo-EM structure of human ABCD1 E630Q in the presence of C26:0-CoA and ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 1, OCTANOYL-COENZYME A
Authors:Chao, X, Li-Na, J, Lin, T.
Deposit date:2022-02-22
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP.
Signal Transduct Target Ther, 8, 2023
7X0Z
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BU of 7x0z by Molmil
Cryo-EM structure of human ABCD1 E630Q in the presence of ATP and Magnesium in outward-facing state
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 1, MAGNESIUM ION
Authors:Chao, X, Li-Na, J, Lin, T.
Deposit date:2022-02-22
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP.
Signal Transduct Target Ther, 8, 2023
7XEC
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BU of 7xec by Molmil
Cryo-EM structure of human ABCD1 E630Q in the presence of ATP in inward-facing state 2
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family D member 1
Authors:Chao, X, Li-Na, J, Lin, T.
Deposit date:2022-03-30
Release date:2023-03-29
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP.
Signal Transduct Target Ther, 8, 2023
7YRQ
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BU of 7yrq by Molmil
Cryo-EM structure of human Peroxisomal ABC Transporter ABCD1
Descriptor: ATP-binding cassette sub-family D member 1, [(2~{R})-1-hexadecanoyloxy-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-propan-2-yl] octadec-9-enoate
Authors:Chao, X, Li-Na, J, Lin, T.
Deposit date:2022-08-10
Release date:2023-03-22
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP.
Signal Transduct Target Ther, 8, 2023
3UXG
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BU of 3uxg by Molmil
Crystal structure of RFXANK
Descriptor: DNA-binding protein RFXANK, Histone deacetylase 4, UNKNOWN ATOM OR ION
Authors:Tempel, W, Chao, X, Bian, C, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-12-05
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
4NW3
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BU of 4nw3 by Molmil
Crystal structure of MLL CXXC domain in complex with a CpG DNA
Descriptor: 5'-D(*GP*CP*CP*AP*TP*CP*GP*AP*TP*GP*GP*C)-3', Histone-lysine N-methyltransferase 2A, ZINC ION
Authors:Bian, C, Tempel, W, Chao, X, Walker, J.R, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2013-12-05
Release date:2014-04-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.
Structure, 26, 2018
4O61
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BU of 4o61 by Molmil
Structure of human ALKBH5 crystallized in the presence of citrate
Descriptor: CITRIC ACID, GLYCEROL, RNA demethylase ALKBH5, ...
Authors:Tempel, W, Chao, X, Liu, K, Dong, A, Cerovina, T, He, H, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2013-12-20
Release date:2014-02-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation.
J.Biol.Chem., 289, 2014
4OCT
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BU of 4oct by Molmil
Crystal structure of human ALKBH5 crystallized in the presence of Mn^{2+} and 2-oxoglutarate
Descriptor: 2-OXOGLUTARIC ACID, MANGANESE (II) ION, RNA demethylase ALKBH5, ...
Authors:Tempel, W, Chao, X, Liu, K, Dong, A, Cerovina, T, He, H, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2014-01-09
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structures of human ALKBH5 demethylase reveal a unique binding mode for specific single-stranded N6-methyladenosine RNA demethylation.
J.Biol.Chem., 289, 2014
3OW8
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BU of 3ow8 by Molmil
Crystal Structure of the WD repeat-containing protein 61
Descriptor: UNKNOWN ATOM OR ION, WD repeat-containing protein 61
Authors:Tempel, W, Li, Z, Chao, X, Lam, R, Wernimont, A.K, He, H, Seitova, A, Pan, P.W, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2010-09-17
Release date:2010-09-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and function of WD40 domain proteins.
Protein Cell, 2, 2011
3Q1J
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BU of 3q1j by Molmil
Crystal structure of tudor domain 1 of human PHD finger protein 20
Descriptor: PHD finger protein 20, UNKNOWN ATOM OR ION
Authors:Tempel, W, Li, Z, Wernimont, A.K, Chao, X, Bian, C, Lam, R, Crombet, L, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2010-12-17
Release date:2011-02-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structures of the Tudor domains of human PHF20 reveal novel structural variations on the Royal Family of proteins.
Febs Lett., 586, 2012
3QII
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BU of 3qii by Molmil
Crystal structure of tudor domain 2 of human PHD finger protein 20
Descriptor: PHD finger protein 20, UNKNOWN ATOM OR ION
Authors:Li, Z, Tempel, W, Wernimont, A.K, Chao, X, Bian, C, Lam, R, Crombet, L, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2011-01-27
Release date:2011-02-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of the Tudor domains of human PHF20 reveal novel structural variations on the Royal Family of proteins.
Febs Lett., 586, 2012

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