Author results

1XG7
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CONSERVED HYPOTHETICAL PROTEIN PFU-877259-001 FROM PYROCOCCUS FURIOSUS
Descriptor:hypothetical protein
Authors:Chang, J., Zhao, M., Horanyi, P., Xu, H., Yang, H., Liu, Z.-J., Chen, L., Zhou, W., Habel, J., Tempel, W., Lee, D., Lin, D., Chang, S.-H., Eneh, J.C., Hopkins, R.C., Jenney Jr., F.E., Lee, H.-S., Li, T., Poole II, F.L., Shah, C., Sugar, F.J., Chen, C.-Y., Arendall III, W.B., Richardson, J.S., Richardson, D.C., Rose, J.P., Adams, M.W.W., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-09-16
Release date:2004-11-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Conserved hypothetical protein Pfu-877259-001 from Pyrococcus furiosus
To be published
1XMA
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STRUCTURE OF A TRANSCRIPTIONAL REGULATOR FROM CLOSTRIDIUM THERMOCELLUM CTH-833
Descriptor:Predicted transcriptional regulator, MERCURY (II) ION, UNKNOWN ATOM OR ION
Authors:Yang, H., Chen, L., Lee, D., Habel, J., Nguyen, J., Chang, S.-H., Kataeva, I., Xu, H., Chang, J., Zhao, M., Horanyi, P., Florence, Q., Zhou, W., Tempel, W., Lin, D., Praissman, J., Zhang, H., Arendall III, W.B., Richardson, J.S., Richardson, D.C., Ljungdahl, L., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-10-01
Release date:2004-12-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Structure of a transcriptional regulator from Clostridium thermocellum Cth-833
To be published
1XRG
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CONSERVED HYPOTHETICAL PROTEIN FROM CLOSTRIDIUM THERMOCELLUM CTH-2968
Descriptor:Putative translation initiation inhibitor, yjgF family, UNKNOWN ATOM OR ION
Authors:Zhao, M., Chang, J., Habel, J., Kataeva, I., Xu, H., Chen, L., Lee, D., Nguyen, J., Chang, S.-H., Horanyi, P., Florence, Q., Zhou, W., Tempel, W., Lin, D., Zhang, H., Arendall III, W.B., Ljundahl, L., Liu, Z.-J., Rose, J., Richardson, J.S., Richardson, D.C., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-10-14
Release date:2004-12-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conserved hypothetical protein from Clostridium thermocellum Cth-2968
To be published
1Y81
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CONSERVED HYPOTHETICAL PROTEIN PFU-723267-001 FROM PYROCOCCUS FURIOSUS
Descriptor:conserved hypothetical protein, THIOCYANATE ION, COENZYME A, ...
Authors:Zhao, M., Chang, J., Habel, J., Xu, H., Chen, L., Lee, D., Nguyen, D., Chang, S.-H., Horanyi, P., Florence, Q., Tempel, W., Zhou, W., Lin, D., Zhang, H., Praissman, J., Jenney Jr., F.E., Adams, M.W.W., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-10
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Conserved hypothetical protein Pfu-723267-001 from Pyrococcus furiosus
To be published
1YB3
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CONSERVED HYPOTHETICAL PROTEIN PFU-178653-001 FROM PYROCOCCUS FURIOSUS
Descriptor:hypothetical protein, UNKNOWN ATOM OR ION
Authors:Habel, J., Zhou, W., Chang, J., Zhao, M., Xu, H., Chen, L., Lee, D., Nguyen, D., Chang, S.-H., Horanyi, P., Florence, Q., Tempel, W., Lin, D., Zhang, H., Praissman, J., Jenney Jr., F.E., Adams, M.W.W., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-19
Release date:2005-02-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Conserved hypothetical protein Pfu-178653-001 from Pyrococcus furiosus
To be published
1YBX
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CONSERVED HYPOTHETICAL PROTEIN CTH-383 FROM CLOSTRIDIUM THERMOCELLUM
Descriptor:Conserved hypothetical protein, UNKNOWN ATOM OR ION
Authors:Tempel, W., Chang, J., Zhao, M., Habel, J., Kataeva, I., Xu, H., Chen, L., Lee, D., Nguyen, J., Chang, S.-H., Horanyi, P., Florence, Q., Zhou, W., Lin, D., Zhang, H., Ljundahl, L., Liu, Z.-J., Rose, J., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-21
Release date:2005-02-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conserved hypothetical protein Cth-383 from Clostridium thermocellum
To be published
1YBY
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CONSERVED HYPOTHETICAL PROTEIN CTH-95 FROM CLOSTRIDIUM THERMOCELLUM
Descriptor:Translation elongation factor P, UNKNOWN ATOM OR ION
Authors:Zhao, M., Zhou, W., Chang, J., Habel, J., Kataeva, I., Xu, H., Chen, L., Lee, D., Nguyen, J., Chang, S.-H., Horanyi, P., Florence, Q., Tempel, W., Lin, D., Zhang, H., Ljundahl, L., Liu, Z.-J., Rose, J., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-21
Release date:2005-02-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Conserved hypothetical protein Cth-95 from Clostridium thermocellum
To be published
1YCY
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CONSERVED HYPOTHETICAL PROTEIN PFU-1806301-001 FROM PYROCOCCUS FURIOSUS
Descriptor:Conserved hypothetical protein
Authors:Huang, L., Liu, Z.-J., Lee, D., Tempel, W., Chang, J., Zhao, M., Habel, J., Xu, H., Chen, L., Nguyen, D., Chang, S.-H., Horanyi, P., Florence, Q., Zhou, W., Lin, D., Zhang, H., Praissman, J., Jenney Jr., F.E., Adams, M.W.W., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-23
Release date:2005-02-22
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Conserved hypothetical protein Pfu-1806301-001 from Pyrococcus furiosus
To be published
1YD7
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CONSERVED HYPOTHETICAL PROTEIN PFU-1647980-001 FROM PYROCOCCUS FURIOSUS
Descriptor:2-keto acid:ferredoxin oxidoreductase subunit alpha, UNKNOWN ATOM OR ION
Authors:Horanyi, P., Florence, Q., Zhou, W., Chang, J., Zhao, M., Habel, J., Xu, H., Chen, L., Lee, D., Nguyen, D., Chang, S.-H., Tempel, W., Lin, D., Zhang, H., Praissman, J., Jenney Jr., F.E., Adams, M.W.W., Liu, Z.-J., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-23
Release date:2005-02-08
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conserved hypothetical protein Pfu-1647980-001 from Pyrococcus furiosus
To be published
1Y80
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STRUCTURE OF A CORRINOID (FACTOR IIIM)-BINDING PROTEIN FROM MOORELLA THERMOACETICA
Descriptor:Predicted cobalamin binding protein, CO-5-METHOXYBENZIMIDAZOLYLCOBAMIDE, UNKNOWN ATOM OR ION
Authors:Liu, Z.-J., Fu, Z.-Q., Tempel, W., Das, A., Habel, J., Zhou, W., Chang, J., Chen, L., Lee, D., Nguyen, D., Chang, S.-H., Ljungdahl, L., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-12-10
Release date:2005-01-25
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of a corrinoid (factor IIIm)-binding protein from Moorella thermoacetica
To be published
1ZGH
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METHIONYL-TRNA FORMYLTRANSFERASE FROM CLOSTRIDIUM THERMOCELLUM
Descriptor:Methionyl-tRNA formyltransferase, UNKNOWN ATOM OR ION
Authors:Yang, H., Kataeva, I., Xu, H., Zhao, M., Chang, J., Liu, Z., Chen, L., Tempel, W., Habel, J., Zhou, W., Lee, D., Lin, D., Chang, S., Arendall III, W.B., Richardson, J.S., Richardson, D.C., Rose, J.P., Wang, B., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-04-21
Release date:2005-05-03
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Methionyl-tRNA formyltransferase from Clostridium thermocellum
To be published
2FZF
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HYPOTHETICAL PROTEIN PFU-1136390-001 FROM PYROCOCCUS FURIOSUS
Descriptor:hypothetical protein
Authors:Fu, Z.-Q., Liu, Z.-J., Lee, D., Kelley, L., Chen, L., Tempel, W., Shah, N., Horanyi, P., Lee, H.S., Habel, J., Dillard, B.D., Nguyen, D., Chang, S.-H., Zhang, H., Chang, J., Sugar, F.J., Poole, F.L., Jenney Jr., F.E., Adams, M.W.W., Rose, J.P., Wang, B.-C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2006-02-09
Release date:2006-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Hypothetical Protein Pfu-1136390-001 From Pyrococcus furiosus
To be published
1VK1
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CONSERVED HYPOTHETICAL PROTEIN FROM PYROCOCCUS FURIOSUS PFU-392566-001
Descriptor:Conserved hypothetical protein, PHOSPHATE ION, SODIUM ION, ...
Authors:Shah, A., Liu, Z.J., Tempel, W., Chen, L., Lee, D., Yang, H., Chang, J., Zhao, M., Ng, J., Rose, J., Brereton, P.S., Izumi, M., Jenney Jr., F.E., Poole II, F.L., Shah, C., Sugar, F.J., Adams, M.W.W., Richardson, D.C., Richardson, J.S., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2004-04-13
Release date:2004-08-10
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:(NZ)CH...O contacts assist crystallization of a ParB-like nuclease.
Bmc Struct.Biol., 7, 2007
2IEL
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CRYSTAL STRUCTURE OF TT0030 FROM THERMUS THERMOPHILUS
Descriptor:Hypothetical Protein TT0030
Authors:Zhu, J., Huang, J., Stepanyuk, G., Chen, L., Chang, J., Zhao, M., Xu, H., Liu, Z.J., Rose, J.P., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2006-09-19
Release date:2006-11-14
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:CRYSTAL STRUCTURE OF TT0030 from Thermus Thermophilus AT 1.6 ANGSTROMS RESOLUTION
To be Published
5VIL
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CRYSTAL STRUCTURE OF ASK1 KINASE DOMAIN WITH A POTENT INHIBITOR (ANALOG 6)
Descriptor:Mitogen-activated protein kinase kinase kinase 5, 2-methoxy-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}-5-sulfamoylbenzamide, DIMETHYL SULFOXIDE
Authors:Jasti, J., Chang, J., Kurumbail, R.
Deposit date:2017-04-17
Release date:2018-01-17
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Rational approach to highly potent and selective apoptosis signal-regulating kinase 1 (ASK1) inhibitors.
Eur J Med Chem, 145, 2017
5VIO
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CRYSTAL STRUCTURE OF ASK1 KINASE DOMAIN WITH A POTENT INHIBITOR (ANALOG 13)
Descriptor:Mitogen-activated protein kinase kinase kinase 5, 4-methoxy-N~1~-methyl-N~3~-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}benzene-1,3-dicarboxamide
Authors:Jasti, J., Chang, J., Kurumbail, R.
Deposit date:2017-04-17
Release date:2018-01-17
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Rational approach to highly potent and selective apoptosis signal-regulating kinase 1 (ASK1) inhibitors.
Eur J Med Chem, 145, 2017
2QVO
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CRYSTAL STRUCTURE OF AF1382 FROM ARCHAEOGLOBUS FULGIDUS
Descriptor:Uncharacterized protein AF_1382
Authors:Zhu, J., Zhao, M., Fu, Z.-Q., Yang, H., Chang, J., Hao, X., Chen, L., Liu, Z.J., Rose, J.P., Wang, B.C., Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2007-08-08
Release date:2007-09-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of AF1382 from Archaeoglobus fulgidus.
To be Published
3UWK
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STRUCTURE GUIDED DEVELOPMENT OF NOVEL THYMIDINE MIMETICS TARGETING PSEUDOMONAS AERUGINOSA THYMIDYLATE KINASE: FROM HIT TO LEAD GENERATION
Descriptor:Thymidylate kinase, 1-methyl-6-phenyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one, MAGNESIUM ION
Authors:Choi, J.Y., Plummer, M.S., Starr, J., Desbonnet, C.R., Soutter, H.H., Chang, J., Miller, J.R., Dillman, K., Miller, A.A., Roush, W.R.
Deposit date:2011-12-02
Release date:2012-02-01
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structure guided development of novel thymidine mimetics targeting Pseudomonas aeruginosa thymidylate kinase: from hit to lead generation.
J.Med.Chem., 55, 2012
3UWO
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STRUCTURE GUIDED DEVELOPMENT OF NOVEL THYMIDINE MIMETICS TARGETING PSEUDOMONAS AERUGINOSA THYMIDYLATE KINASE: FROM HIT TO LEAD GENERATION
Descriptor:Thymidylate kinase, 3-(1-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-6-yl)benzamide
Authors:Choi, J.Y., Plummer, M.S., Starr, J., Desbonnet, C.R., Soutter, H.H., Chang, J., Miller, J.R., Dillman, K., Miller, A.A., Roush, W.R.
Deposit date:2011-12-02
Release date:2012-02-01
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure guided development of novel thymidine mimetics targeting Pseudomonas aeruginosa thymidylate kinase: from hit to lead generation.
J.Med.Chem., 55, 2012
3UXM
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STRUCTURE GUIDED DEVELOPMENT OF NOVEL THYMIDINE MIMETICS TARGETING PSEUDOMONAS AERUGINOSA THYMIDYLATE KINASE: FROM HIT TO LEAD GENERATION
Descriptor:Thymidylate kinase, MAGNESIUM ION, 5'-deoxy-5'-fluorothymidine
Authors:Choi, J.Y., Plummer, M.S., Starr, J., Desbonnet, C.R., Soutter, H.H., Chang, J., Miller, J.R., Dillman, K., Miller, A.A., Roush, W.R.
Deposit date:2011-12-05
Release date:2012-02-01
Last modified:2012-11-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure guided development of novel thymidine mimetics targeting Pseudomonas aeruginosa thymidylate kinase: from hit to lead generation.
J.Med.Chem., 55, 2012
5C26
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CRYSTAL STRUCTURE OF SYK IN COMPLEX WITH COMPOUND 1
Descriptor:Tyrosine-protein kinase SYK, GLU-VAL-PTR-GLU-SER-PRO, 3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}benzamide
Authors:Han, S., Chang, J.
Deposit date:2015-06-15
Release date:2015-10-07
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Imidazotriazines: Spleen Tyrosine Kinase (Syk) Inhibitors Identified by Free-Energy Perturbation (FEP).
Chemmedchem, 11, 2016
5C27
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CRYSTAL STRUCTURE OF SYK IN COMPLEX WITH COMPOUND 2
Descriptor:Tyrosine-protein kinase SYK, GLU-VAL-TYR-GLU-SER, 3-{8-[(3,4-dimethoxyphenyl)amino]imidazo[1,2-a]pyrazin-6-yl}-N-[4-(methylcarbamoyl)phenyl]benzamide, ...
Authors:Han, S., Chang, J.
Deposit date:2015-06-15
Release date:2015-10-07
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Imidazotriazines: Spleen Tyrosine Kinase (Syk) Inhibitors Identified by Free-Energy Perturbation (FEP).
Chemmedchem, 11, 2016
5XJX
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PRE-FORMED PLANT RECETOR ERL1-TMM COMPLEXE
Descriptor:Protein TOO MANY MOUTHS, LRR receptor-like serine/threonine-protein kinase ERL1
Authors:Chai, J., Lin, G., Zhang, L., Han, Z., Yang, X., Liu, W., Qi, Y., Chang, J., Li, E.
Deposit date:2017-05-04
Release date:2019-01-23
Method:X-RAY DIFFRACTION (3.055 Å)
Cite:A receptor-like protein acts as a specificity switch for the regulation of stomatal development.
Genes Dev., 31, 2017
1RQ5
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STRUCTURAL BASIS FOR THE EXOCELLULASE ACTIVITY OF THE CELLOBIOHYDROLASE CBHA FROM C. THERMOCELLUM
Descriptor:Cellobiohydrolase, CALCIUM ION, beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranose
Authors:Schubot, F.D., Kataeva, I.A., Chang, J., Shah, A.K., Ljungdahl, L.G., Rose, J.P., Wang, B.C.
Deposit date:2003-12-04
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the exocellulase activity of the cellobiohydrolase CbhA from Clostridium thermocellum
Biochemistry, 43, 2004
1UT9
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STRUCTURAL BASIS FOR THE EXOCELLULASE ACTIVITY OF THE CELLOBIOHYDROLASE CBHA FROM C. THERMOCELLUM
Descriptor:CELLULOSE 1,4-BETA-CELLOBIOSIDASE
Authors:Schubot, F.D., Kataeva, I.A., Chang, J., Shah, A.K., Ljungdahl, L.G., Rose, J.P., Wang, B.C.
Deposit date:2003-12-04
Release date:2004-02-12
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for the exocellulase activity of the cellobiohydrolase CbhA from Clostridium thermocellum.
Biochemistry, 43, 2004
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