Author results

6E6I
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CRYSTAL STRUCTURE OF 4-METHYL HOPDA BOUND TO LIGY FROM SPHINGOBIUM SP. STRAIN SYK-6
Descriptor:2,2',3-trihydroxy-3'-methoxy-5,5'-dicarboxybiphenyl meta-cleavage compound hydrolase, ZINC ION, (1Z,3E)-5-carboxy-3-methyl-5-oxo-1-phenylpenta-1,3-dien-1-olate
Authors:Kuatsjah, E., Chan, A.C., Hurst, T.E., Snieckus, V., Murphy, M.E., Eltis, L.D.
Deposit date:2018-07-24
Release date:2019-01-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Metal- and Serine-Dependent Meta-Cleavage Product Hydrolases Utilize Similar Nucleophile-Activation Strategies
Acs Catalysis, 8, 2018
5VMM
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STAPHYLOCOCCUS AUREUS ISDB BOUND TO HUMAN HEMOGLOBIN
Descriptor:Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated cell wall-anchored protein, ...
Authors:Bowden, C.F., Chan, A.C., Murphy, M.E.
Deposit date:2017-04-27
Release date:2017-11-15
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure-function analyses reveal key features in Staphylococcus aureus IsdB-associated unfolding of the heme-binding pocket of human hemoglobin.
J. Biol. Chem., 293, 2018
5I0V
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IRON AND COPPER-BOUND P19 FROM CAMPYLOBACTER JEJUNI UNDER OXIDIZING CONDITIONS
Descriptor:Protein P19, FE (III) ION, COPPER (II) ION, ...
Authors:Chan, A.C., Murphy, M.E.
Deposit date:2016-02-04
Release date:2017-02-08
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Metal-handling and Receptor Recognition by FetP and P19 from Uropathogenic Escherichia coli and Campylobacter jejuni
TO BE PUBLISHED
5I0W
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IRON AND COPPER-BOUND P19 FROM CAMPYLOBACTER JEJUNI UNDER REDUCING CONDITIONS
Descriptor:P19, TRIS(HYDROXYETHYL)AMINOMETHANE, COPPER (I) ION, ...
Authors:Chan, A.C., Murphy, M.E.
Deposit date:2016-02-04
Release date:2017-02-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Metal-handling and Receptor Recognition by FetP and P19 from Uropathogenic Escherichia coli and Campylobacter jejuni
TO BE PUBLISHED
5I0X
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COPPER-BOUND M90I VARIANT OF UROPATHOGENIC ESCHERICHIA COLI STRAIN F11 FETP
Descriptor:Periplasmic protein-probably involved in high-affinity Fe2+ transport, COPPER (II) ION
Authors:Chan, A.C., Murphy, M.E.
Deposit date:2016-02-04
Release date:2017-02-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Metal-handling and Receptor Recognition by FetP and P19 from Uropathogenic Escherichia coli and Campylobacter jejuni
TO BE PUBLISHED
5I0Y
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COPPER-BOUND E46Q VARIANT OF UROPATHOGENIC ESCHERICHIA COLI STRAIN F11 FETP
Descriptor:Periplasmic protein-probably involved in high-affinity Fe2+ transport, COPPER (II) ION
Authors:Chan, A.C., Murphy, M.E.
Deposit date:2016-02-04
Release date:2017-02-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Metal-handling and Receptor Recognition by FetP and P19 from Uropathogenic Escherichia coli and Campylobacter jejuni
TO BE PUBLISHED
5D2R
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INHIBITOR BOUND CELL SHAPE DETERMINANT PROTEIN CSD4 FROM HELICOBACTER PYLORI
Descriptor:Conserved hypothetical secreted protein, ZINC ION, IODIDE ION, ...
Authors:Chan, A.C., Murphy, M.E.
Deposit date:2015-08-06
Release date:2016-01-20
Last modified:2016-04-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Bacterial Cell Shape-Determining Inhibitor.
Acs Chem.Biol., 11, 2016
4WCK
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CRYSTAL STRUCTURE OF APO CELL SHAPE DETERMINANT PROTEIN CSD4 FROM HELICOBACTER PYLORI
Descriptor:Conserved hypothetical secreted protein, IODIDE ION, 2,6-DIAMINOPIMELIC ACID
Authors:Chan, A.C., Murphy, M.E.
Deposit date:2014-09-05
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Helical Shape of Helicobacter pylori Requires an Atypical Glutamine as a Zinc Ligand in the Carboxypeptidase Csd4.
J.Biol.Chem., 290, 2015
4WCL
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CRYSTAL STRUCTURE OF PRODUCT BOUND CELL SHAPE DETERMINANT PROTEIN CSD4 FROM HELICOBACTER PYLORI
Descriptor:Conserved hypothetical secreted protein, ZINC ION, IODIDE ION, ...
Authors:Chan, A.C., Murphy, M.E.
Deposit date:2014-09-05
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Helical Shape of Helicobacter pylori Requires an Atypical Glutamine as a Zinc Ligand in the Carboxypeptidase Csd4.
J.Biol.Chem., 290, 2015
4WCM
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CRYSTAL STRUCTURE OF CELL SHAPE DETERMINANT PROTEIN CSD4 GLN46HIS VARIANT FROM HELICOBACTER PYLORI
Descriptor:Conserved hypothetical secreted protein, IODIDE ION, ZINC ION, ...
Authors:Chan, A.C., Murphy, M.E.
Deposit date:2014-09-05
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Helical Shape of Helicobacter pylori Requires an Atypical Glutamine as a Zinc Ligand in the Carboxypeptidase Csd4.
J.Biol.Chem., 290, 2015
4WCN
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CRYSTAL STRUCTURE OF TRIPEPTIDE BOUND CELL SHAPE DETERMINANT CSD4 PROTEIN FROM HELICOBACTER PYLORI
Descriptor:Conserved hypothetical secreted protein, IODIDE ION, ZINC ION, ...
Authors:Chan, A.C., Murphy, M.E.
Deposit date:2014-09-05
Release date:2014-12-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Helical Shape of Helicobacter pylori Requires an Atypical Glutamine as a Zinc Ligand in the Carboxypeptidase Csd4.
J.Biol.Chem., 290, 2015
4MHG
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CRYSTAL STRUCTURE OF ETV6 BOUND TO A SPECIFIC DNA SEQUENCE
Descriptor:Specific 14 bp DNA, Complementary Specific 14 bp DNA, Transcription factor ETV6
Authors:Chan, A.C., De, S., Coyne III, H.J., Okon, M., Murphy, M.E., Graves, B.J., McIntosh, L.P.
Deposit date:2013-08-29
Release date:2014-01-08
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6.
J.Mol.Biol., 426, 2014
2MD5
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STRUCTURE OF UNINHIBITED ETV6 ETS DOMAIN
Descriptor:Transcription factor ETV6
Authors:De, S., Mcintosh, L.P., Chan, A.C., Coyne, H.J., Okon, M., Graves, B.J., Murphy, M.E.
Deposit date:2013-08-29
Release date:2013-12-25
Last modified:2014-04-02
Method:SOLUTION NMR
Cite:Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6.
J.Mol.Biol., 426, 2014
3NRP
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CRYSTAL STRUCTURE OF 'AS ISOLATED' UROPATHOGENIC E. COLI STRAIN F11 FETP RECOMBINANTLY EXPRESSED IN THE PERIPLASM OF E. COLI BL21(DE3)
Descriptor:Periplasmic protein-probably involved in high-affinity Fe2+ transport
Authors:Chan, A.C.K., Murphy, M.E.P.
Deposit date:2010-06-30
Release date:2011-05-18
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Characterization of a Dipartite Iron Uptake System from Uropathogenic Escherichia coli Strain F11.
J.Biol.Chem., 286, 2011
3NRQ
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CRYSTAL STRUCTURE OF COPPER-RECONSTITUTED FETP FROM UROPATHOGENIC ESCHERICHIA COLI STRAIN F11
Descriptor:Periplasmic protein-probably involved in high-affinity Fe2+ transport, COPPER (II) ION
Authors:Chan, A.C.K., Murphy, M.E.P.
Deposit date:2010-06-30
Release date:2011-05-18
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Characterization of a Dipartite Iron Uptake System from Uropathogenic Escherichia coli Strain F11.
J.Biol.Chem., 286, 2011
3LZL
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CRYSTAL STRUCTURE ANALYSIS OF THE AS-SOLATED P19 PROTEIN FROM CAMPYLOBACTER JEJUNI AT 1.45 A AT PH 9.0
Descriptor:P19 protein, COPPER (II) ION, SULFATE ION
Authors:Doukov, T.I., Chan, A.C.K., Scofield, M., Ramin, A.B., Tom-Yew, S.A.L., Murphy, M.E.P.
Deposit date:2010-03-01
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure and Function of P19, a High-Affinity Iron Transporter of the Human Pathogen Campylobacter jejuni.
J.Mol.Biol., 401, 2010
3LZN
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CRYSTAL STRUCTURE ANALYSIS OF THE APO P19 PROTEIN FROM CAMPYLOBACTER JEJUNI AT 1.59 A AT PH 9
Descriptor:P19 protein, ZINC ION, SULFATE ION
Authors:Doukov, T.I., Chan, A.C.K., Scofield, M., Ramin, A.B., Tom-Yew, S.A.L., Murphy, M.E.P.
Deposit date:2010-03-01
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structure and Function of P19, a High-Affinity Iron Transporter of the Human Pathogen Campylobacter jejuni.
J.Mol.Biol., 401, 2010
3LZO
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CRYSTAL STRUCTURE ANALYSIS OF THE COPPER-RECONSTITUTED P19 PROTEIN FROM CAMPYLOBACTER JEJUNI AT 1.65 A AT PH 10.0
Descriptor:P19 protein, COPPER (II) ION, SULFATE ION
Authors:Doukov, T.I., Chan, A.C.K., Scofield, M., Ramin, A.B., Tom-Yew, S.A.L., Murphy, M.E.P.
Deposit date:2010-03-01
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and Function of P19, a High-Affinity Iron Transporter of the Human Pathogen Campylobacter jejuni.
J.Mol.Biol., 401, 2010
3LZP
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CRYSTAL STRUCTURE ANALYSIS OF THE 'AS-ISOLATED' P19 PROTEIN FROM CAMPYLOBACTER JEJUNI AT 1.65 A AT PH 9.0
Descriptor:P19 protein, COPPER (II) ION, SULFATE ION
Authors:Doukov, T.I., Chan, A.C.K., Scofield, M., Ramin, A.B., Tom-Yew, S.A.L., Murphy, M.E.P.
Deposit date:2010-03-01
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure and Function of P19, a High-Affinity Iron Transporter of the Human Pathogen Campylobacter jejuni.
J.Mol.Biol., 401, 2010
3LZQ
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CRYSTAL STRUCTURE ANALYSIS OF MANGANESE TREATED P19 PROTEIN FROM CAMPYLOBACTER JEJUNI AT 1.41 A AT PH 9
Descriptor:P19 protein, COPPER (II) ION, MANGANESE (II) ION, ...
Authors:Doukov, T.I., Chan, A.C.K., Scofield, M., Ramin, A.B., Tom-Yew, S.A.L., Murphy, M.E.P.
Deposit date:2010-03-01
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structure and Function of P19, a High-Affinity Iron Transporter of the Human Pathogen Campylobacter jejuni.
J.Mol.Biol., 401, 2010
3LZR
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CRYSTAL STRUCTURE ANALYSIS OF MANGANESE TREATED P19 PROTEIN FROM CAMPYLOBACTER JEJUNI AT 2.73 A AT PH 9 AND MANGANESE PEAK WAVELENGTH (1.893 A)
Descriptor:P19 protein, COPPER (II) ION, MANGANESE (II) ION, ...
Authors:Doukov, T.I., Chan, A.C.K., Scofield, M., Ramin, A.B., Tom-Yew, S.A.L., Murphy, M.E.P.
Deposit date:2010-03-01
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Structure and Function of P19, a High-Affinity Iron Transporter of the Human Pathogen Campylobacter jejuni.
J.Mol.Biol., 401, 2010
2G5G
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COFACIAL HEME BINDING TO CHAN OF CAMPYLOBACTER JEJUNI
Descriptor:putative lipoprotein, PROTOPORPHYRIN IX CONTAINING FE
Authors:Chan, A.C., Murphy, M.E.
Deposit date:2006-02-22
Release date:2006-10-03
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Cofacial Heme Binding is Linked to Dimerization by a Bacterial Heme Transport Protein.
J.Mol.Biol., 362, 2006
1A81
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CRYSTAL STRUCTURE OF THE TANDEM SH2 DOMAIN OF THE SYK KINASE BOUND TO A DUALLY TYROSINE-PHOSPHORYLATED ITAM
Descriptor:SYK KINASE, T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN
Authors:Fuetterer, K., Waksman, G.
Deposit date:1998-03-31
Release date:1998-10-21
Last modified:2016-05-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide.
J.Mol.Biol., 281, 1998