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6YE4
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BU of 6ye4 by Molmil
Structure of ExbB pentamer from Serratia marcescens by single particle cryo electron microscopy
Descriptor: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Biopolymer transport protein ExbB
Authors:Biou, V, Delepelaire, P, Coureux, P.D, Chami, M.
Deposit date:2020-03-24
Release date:2021-03-31
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural and molecular determinants for the interaction of ExbB from Serratia marcescens and HasB, a TonB paralog.
Commun Biol, 5, 2022
7ZNQ
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BU of 7znq by Molmil
ABC transporter complex NosDFYL in GDN
Descriptor: COPPER (II) ION, Copper-binding lipoprotein NosL, MAGNESIUM ION, ...
Authors:Zhang, L, Mueller, C, Zipfel, S, Chami, M, Einsle, O.
Deposit date:2022-04-21
Release date:2022-08-03
Last modified:2022-10-26
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Molecular interplay of an assembly machinery for nitrous oxide reductase.
Nature, 608, 2022
7AA5
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BU of 7aa5 by Molmil
Human TRPV4 structure in presence of 4a-PDD
Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily V member 4,Green fluorescent protein
Authors:Botte, M, Ulrich, A.K.G, Adaixo, R, Gnutt, D, Brockmann, A, Bucher, D, Chami, M, Bocquet, M, Ebbinghaus-Kintscher, U, Puetter, V, Becker, A, Egner, U, Stahlberg, H, Hennig, M, Holton, S.J.
Deposit date:2020-09-03
Release date:2021-08-18
Method:ELECTRON MICROSCOPY (4.18 Å)
Cite:Cryo-EM structural studies of the agonist complexed human TRPV4 ion-channel reveals novel structural rearrangements resulting in an open-conformation
To Be Published
7AJQ
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BU of 7ajq by Molmil
cryo-EM structure of ExbBD from Serratia Marcescens
Descriptor: Biopolymer transport protein ExbB, Biopolymer transport protein ExbD
Authors:Biou, V, Adaixo, R, Coureux, P.D, Delepelaire, P, Chami, M.
Deposit date:2020-09-29
Release date:2021-10-06
Last modified:2022-05-04
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural and molecular determinants for the interaction of ExbB from Serratia marcescens and HasB, a TonB paralog.
Commun Biol, 5, 2022
4CHW
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BU of 4chw by Molmil
The electron crystallography structure of the cAMP-free potassium channel MloK1
Descriptor: CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION
Authors:Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H.
Deposit date:2013-12-04
Release date:2014-01-15
Last modified:2019-04-24
Method:ELECTRON CRYSTALLOGRAPHY (7 Å)
Cite:Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1.
Nat Commun, 5, 2014
4CHV
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BU of 4chv by Molmil
The electron crystallography structure of the cAMP-bound potassium channel MloK1
Descriptor: CYCLIC NUCLEOTIDE-GATED POTASSIUM CHANNEL MLL3241, POTASSIUM ION
Authors:Kowal, J, Chami, M, Baumgartner, P, Arheit, M, Chiu, P.L, Rangl, M, Scheuring, S, Schroeder, G.F, Nimigean, C.M, Stahlberg, H.
Deposit date:2013-12-04
Release date:2014-01-15
Last modified:2019-04-24
Method:ELECTRON CRYSTALLOGRAPHY (7 Å)
Cite:Ligand-Induced Structural Changes in the Cyclic Nucleotide-Modulated Potassium Channel Mlok1
Nat.Commun., 5, 2014
2N1F
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BU of 2n1f by Molmil
Structure and assembly of the mouse ASC filament by combined NMR spectroscopy and cryo-electron microscopy
Descriptor: Apoptosis-associated speck-like protein
Authors:Sborgi, L, Ravotti, F, Dandey, V, Dick, M, Mazur, A, Reckel, S, Chami, M, Scherer, S, Bockmann, A, Egelman, E, Stahlberg, H, Broz, P, Meier, B, Hiller, S.
Deposit date:2015-04-01
Release date:2015-10-14
Last modified:2023-06-14
Method:ELECTRON MICROSCOPY (4 Å), SOLID-STATE NMR
Cite:Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy.
Proc.Natl.Acad.Sci.USA, 112, 2015
6G2H
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BU of 6g2h by Molmil
Filament of acetyl-CoA carboxylase and BRCT domains of BRCA1 (ACC-BRCT) core at 4.6 A resolution
Descriptor: Acetyl-CoA carboxylase 1
Authors:Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T.
Deposit date:2018-03-23
Release date:2018-06-13
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis for regulation of human acetyl-CoA carboxylase.
Nature, 558, 2018
6G2I
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BU of 6g2i by Molmil
Filament of acetyl-CoA carboxylase and BRCT domains of BRCA1 (ACC-BRCT) at 5.9 A resolution
Descriptor: Acetyl-CoA carboxylase 1, Breast cancer type 1 susceptibility protein
Authors:Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T.
Deposit date:2018-03-23
Release date:2018-06-13
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Structural basis for regulation of human acetyl-CoA carboxylase.
Nature, 558, 2018
6G2D
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BU of 6g2d by Molmil
Citrate-induced acetyl-CoA carboxylase (ACC-Cit) filament at 5.4 A resolution
Descriptor: Acetyl-CoA carboxylase 1
Authors:Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T.
Deposit date:2018-03-23
Release date:2018-06-13
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Structural basis for regulation of human acetyl-CoA carboxylase.
Nature, 558, 2018
6TY3
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BU of 6ty3 by Molmil
FAK structure from single particle analysis of 2D crystals
Descriptor: Focal adhesion kinase 1
Authors:Acebron, I, Righetto, R, Biyani, N, Chami, M, Boskovic, J, Stahlberg, H, Lietha, D.
Deposit date:2020-01-15
Release date:2020-08-19
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (6.32 Å)
Cite:Structural basis of Focal Adhesion Kinase activation on lipid membranes.
Embo J., 39, 2020
6TY4
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BU of 6ty4 by Molmil
FAK structure with AMP-PNP from single particle analysis of 2D crystals
Descriptor: Focal adhesion kinase 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Acebron, I, Righetto, R, Biyani, N, Chami, M, Boskovic, J, Stahlberg, H, Lietha, D.
Deposit date:2020-01-15
Release date:2020-08-19
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (5.96 Å)
Cite:Structural basis of Focal Adhesion Kinase activation on lipid membranes.
Embo J., 39, 2020
6EO1
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BU of 6eo1 by Molmil
The electron crystallography structure of the cAMP-bound potassium channel MloK1 (PCO-refined)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Kowal, J, Biyani, N, Chami, M, Scherer, S, Rzepiela, A, Baumgartner, P, Upadhyay, V, Nimigean, C, Stahlberg, H.
Deposit date:2017-10-08
Release date:2017-12-27
Last modified:2018-01-10
Method:ELECTRON CRYSTALLOGRAPHY (4.5 Å)
Cite:High-Resolution Cryoelectron Microscopy Structure of the Cyclic Nucleotide-Modulated Potassium Channel MloK1 in a Lipid Bilayer.
Structure, 26, 2018
6I9D
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BU of 6i9d by Molmil
MloK1 consensus structure from single particle analysis of 2D crystals
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-11-23
Release date:2019-04-24
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
6IAX
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BU of 6iax by Molmil
MloK1 model from single particle analysis of 2D crystals, class 1 (extended conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-11-27
Release date:2019-04-24
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
6QCY
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BU of 6qcy by Molmil
MloK1 model from single particle analysis of 2D crystals, class 2 (intermediate conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
6QD2
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BU of 6qd2 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 6 (intermediate compact conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
6QD0
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BU of 6qd0 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 4 (compact/open conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
6QCZ
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BU of 6qcz by Molmil
MloK1 model from single particle analysis of 2D crystals, class 3 (intermediate extended conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
6QD3
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BU of 6qd3 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 7 (intermediate conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
6QD1
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BU of 6qd1 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 5 (intermediate compact conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
6QD4
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BU of 6qd4 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 8 (intermediate conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
7OMM
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BU of 7omm by Molmil
Cryo-EM structure of N. gonorhoeae LptDE in complex with ProMacrobodies (MBPs have not been built de novo)
Descriptor: LPS-assembly lipoprotein LptE, LPS-assembly protein LptD, ProMacrobody 21,Maltodextrin-binding protein, ...
Authors:Botte, M, Ni, D, Schenck, S, Zimmermann, I, Chami, M, Bocquet, N, Egloff, P, Bucher, D, Trabuco, M, Cheng, R.K.Y, Brunner, J.D, Seeger, M.A, Stahlberg, H, Hennig, M.
Deposit date:2021-05-24
Release date:2022-05-04
Last modified:2022-05-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of a LptDE transporter in complex with Pro-macrobodies offer insight into lipopolysaccharide translocation.
Nat Commun, 13, 2022
7OMT
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BU of 7omt by Molmil
Crystal structure of ProMacrobody 21 with bound maltose
Descriptor: HEXAETHYLENE GLYCOL, MAGNESIUM ION, ProMacrobody 21, ...
Authors:Botte, M, Ni, D, Schenck, S, Zimmermann, I, Chami, M, Bocquet, N, Egloff, P, Bucher, D, Trabuco, M, Cheng, R.K.Y, Brunner, J.D, Seeger, M.A, Stahlberg, H, Hennig, M.
Deposit date:2021-05-24
Release date:2022-05-04
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cryo-EM structures of a LptDE transporter in complex with Pro-macrobodies offer insight into lipopolysaccharide translocation.
Nat Commun, 13, 2022
7PQT
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BU of 7pqt by Molmil
Apo human Kv3.1 cryo-EM structure
Descriptor: POTASSIUM ION, Potassium voltage-gated channel subfamily C member 1
Authors:Botte, M, Huber, S, Bucher, D, Klint, J.K, Rodriguez, D, Tagmose, L, Chami, M, Cheng, R, Hennig, M, Abdul Rhaman, W.
Deposit date:2021-09-20
Release date:2022-08-17
Last modified:2023-02-15
Method:ELECTRON MICROSCOPY (2.65 Å)
Cite:Apo and ligand-bound high resolution Cryo-EM structures of the human Kv3.1 channel reveal a novel binding site for positive modulators.
Pnas Nexus, 1, 2022

 

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